Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Cheng Y and Li ZK | [Changes of neurotransmitter endothelin, thromboxance B2 and 6-keto-prostaglandin F1 alpha in patients with chronic pulmonary heart disease]. | 2010 | Nan Fang Yi Ke Da Xue Xue Bao | pmid:20584647 |
Boutaud O and Oates JA | Study of inhibitors of the PGH synthases for which potency is regulated by the redox state of the enzymes. | 2010 | Methods Mol. Biol. | pmid:20645166 |
Kawaguchi T et al. | The human megakaryocytic cell line UT-7/TPO expresses functional platelet agonist signals mediated through GPVI and thromboxane receptor. | 2010 | Cell Biol. Int. | pmid:20522022 |
Huntjens DR et al. | Impact of chronic inflammation on the pharmacokinetic-pharmacodynamic relationship of naproxen. | 2010 | Eur J Pain | pmid:19679500 |
Dołegowska B et al. | Dynamics of thromboxane level changes during early phase of allograft reperfusion. | 2009 Sep-Oct | Clin Transplant | pmid:19298388 |
Tantry US et al. | Aspirin resistance. | 2009 Sep-Oct | Prog Cardiovasc Dis | pmid:19732606 |
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Seta F et al. | Renal and cardiovascular characterization of COX-2 knockdown mice. | 2009 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:19357295 |
Pettinella C et al. | Cyclooxygenase-1 haplotype C50T/A-842G does not affect platelet response to aspirin. | 2009 | Thromb. Haemost. | pmid:19350112 |
Basselin M et al. | Imaging elevated brain arachidonic acid signaling in unanesthetized serotonin transporter (5-HTT)-deficient mice. | 2009 | Neuropsychopharmacology | pmid:19145225 |
Guagnano MT et al. | Determinants of platelet activation in hypertensives with microalbuminuria. | 2009 | Free Radic. Biol. Med. | pmid:19280705 |
Lo HM et al. | 2'-Ethoxy-5'-methoxy-2-(5-methylthienyl)chalcone inhibits collagen-induced protein tyrosine phosphorylation and thromboxane formation during platelet aggregation and adhesion. | 2009 | Pharmacology | pmid:19690443 |
Struthmann L et al. | Prothrombotic effects of diclofenac on arteriolar platelet activation and thrombosis in vivo. | 2009 | J. Thromb. Haemost. | pmid:19691487 |
Mayer K et al. | Acute lung injury is reduced in fat-1 mice endogenously synthesizing n-3 fatty acids. | 2009 | Am. J. Respir. Crit. Care Med. | pmid:19136374 |
Zhang X et al. | Effect of baicalin on inflammatory mediator levels and microcirculation disturbance in rats with severe acute pancreatitis. | 2009 | Pancreas | pmid:19657312 |
Liu FC et al. | A new insight of anti-platelet effects of sirtinol in platelets aggregation via cyclic AMP phosphodiesterase. | 2009 | Biochem. Pharmacol. | pmid:19426675 |
Peng CY et al. | Dietary soy protein selectively reduces renal prostanoids and cyclooxygenases in polycystic kidney disease. | 2009 | Exp. Biol. Med. (Maywood) | pmid:19429858 |
Li H et al. | [Effect of an integrative medical regimen on levels of vascular endothelial function and hypersensitive C-reactive protein in elderly patients with isolated systolic hypertension]. | 2009 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:19382469 |