Thromboxane b2
Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
Cross Reference
Introduction
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Thromboxane b2?
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Thromboxane b2
PubChem Associated disorders and diseases
What pathways are associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Thromboxane b2?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Thromboxane b2?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
What genes are associated with Thromboxane b2?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Thromboxane b2
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Sheu JR et al. | Mechanisms involved in the antiplatelet activity of Escherichia coli lipopolysaccharide in human platelets. | 1998 | Br. J. Haematol. | pmid:9792285 |
| Smith CJ et al. | Pharmacological analysis of cyclooxygenase-1 in inflammation. | 1998 | Proc. Natl. Acad. Sci. U.S.A. | pmid:9789085 |
| Thomson M et al. | Prostanoid synthesis in whole blood cells from fish of the Arabian Gulf. | 1998 | Comp. Biochem. Physiol. B, Biochem. Mol. Biol. | pmid:9787758 |
| John H et al. | Development and review of radioimmunoassay of 12-S-hydroxyheptadecatrienoic acid. | 1998 | Prostaglandins Other Lipid Mediat. | pmid:9785378 |
| Lindström T et al. | The effect of unreamed and reamed intramedullary nailing on the urinary excretion of prostacyclin and thromboxane A2 metabolites in patients with tibial shaft fractures. | 1998 | J Trauma | pmid:9783614 |
| Chen MF et al. | Vitamin E supplementation attenuates myointimal proliferation of the abdominal aorta after balloon injury in diet-induced hypercholesterolemic rabbits. | 1998 | Prostaglandins Other Lipid Mediat. | pmid:9777654 |
| Chavali SR et al. | Increased production of TNF-alpha and decreased levels of dienoic eicosanoids, IL-6 and IL-10 in mice fed menhaden oil and juniper oil diets in response to an intraperitoneal lethal dose of LPS. | 1998 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:9774171 |
| Power I et al. | Effects of ketorolac and dextran-70 alone and in combination on haemostasis. | 1998 | Acta Anaesthesiol Scand | pmid:9773144 |
| Brinkmann A et al. | Vasopressor hormone response following mesenteric traction during major abdominal surgery. | 1998 | Acta Anaesthesiol Scand | pmid:9773140 |
| Yan DH et al. | [Study on experimental parameters for diagnosing ganyang huafeng syndrome of cerebral infarction]. | 1996 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:9772617 |
| van Dijk AP et al. | Transdermal nicotine inhibits interleukin 2 synthesis by mononuclear cells derived from healthy volunteers. | 1998 | Eur. J. Clin. Invest. | pmid:9767362 |
| Oosaki R et al. | Correlation among urinary eosinophil protein X, leukotriene E4, and 11-dehydrothromboxane B2 in patients with spontaneous asthmatic attack. | 1998 | Clin. Exp. Allergy | pmid:9761018 |
| Gajdos M et al. | Effective long-term inhibition of thromboxane production but not of serotonin release in patients with coronary heart disease by 30 mg/d acetylsalicylic acid dosage. | 1998 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:9758203 |
| Simon LS et al. | Preliminary study of the safety and efficacy of SC-58635, a novel cyclooxygenase 2 inhibitor: efficacy and safety in two placebo-controlled trials in osteoarthritis and rheumatoid arthritis, and studies of gastrointestinal and platelet effects. | 1998 | Arthritis Rheum. | pmid:9751091 |
| Gonchar MV et al. | Lack of direct connection between arachidonic acid release and prostanoid synthesis upon differentiation of U937 cell. | 1998 | Biochem. Biophys. Res. Commun. | pmid:9731221 |
| Roberts LJ et al. | Metabolism of thromboxane B2 in the monkey. | 1978 | J. Biol. Chem. | pmid:97291 |
| Jain SK et al. | Relationship of blood thromboxane-B2 (TxB2) with lipid peroxides and effect of vitamin E and placebo supplementation on TxB2 and lipid peroxide levels in type 1 diabetic patients. | 1998 | Diabetes Care | pmid:9727900 |
| Takami M and Tsukada W | In vitro effect of DP-1904, a novel anti-asthma agent, against antigen-induced constriction and TXB2 release from the isolated guinea-pig lung parenchymal tissue. | 1998 | Pharmacol. Res. | pmid:9721602 |
| Takami M and Tsukada W | Correlative alteration of thromboxane A2 with antigen-induced bronchoconstriction and the role of platelets as a source of TXA2 synthesis in guinea pigs: effect of DP-1904, an inhibitor of thromboxane synthetase. | 1998 | Pharmacol. Res. | pmid:9721601 |
| Saareks V et al. | Nicotine stereoisomers and cotinine stimulate prostaglandin E2 but inhibit thromboxane B2 and leukotriene E4 synthesis in whole blood. | 1998 | Eur. J. Pharmacol. | pmid:9721044 |