Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

Cross Reference

Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Frostbite D005627 1 associated lipids
Strongyle Infections, Equine D013319 1 associated lipids
Basal Ganglia Hemorrhage D020145 1 associated lipids
Osteoblastoma D018215 1 associated lipids
Edema, Cardiac D004489 1 associated lipids
Radiculopathy D011843 1 associated lipids
Oligomenorrhea D009839 1 associated lipids
Erythromelalgia D004916 1 associated lipids
Intracranial Hemorrhage, Hypertensive D020299 1 associated lipids
Cholecystitis, Acute D041881 1 associated lipids
Bluetongue D001819 1 associated lipids
Atrial Premature Complexes D018880 1 associated lipids
Gastric Dilatation D013271 1 associated lipids
Latex Hypersensitivity D020315 1 associated lipids
Stomach Volvulus D013277 1 associated lipids
Foot Rot D005535 1 associated lipids
Aortic Arch Syndromes D001015 2 associated lipids
Tachycardia, Paroxysmal D013614 2 associated lipids
Mixed Connective Tissue Disease D008947 2 associated lipids
Fibromuscular Dysplasia D005352 2 associated lipids
Heart Septal Defects D006343 2 associated lipids
Retinal Vein Occlusion D012170 2 associated lipids
Weil Disease D014895 2 associated lipids
Drowning D004332 2 associated lipids
Pulmonary Heart Disease D011660 2 associated lipids
Angina Pectoris, Variant D000788 3 associated lipids
Jejunal Diseases D007579 3 associated lipids
Pneumonia, Viral D011024 3 associated lipids
Platelet Storage Pool Deficiency D010981 3 associated lipids
Takayasu Arteritis D013625 3 associated lipids
Tachycardia, Supraventricular D013617 3 associated lipids
Pneumonia, Aspiration D011015 3 associated lipids
Infertility D007246 3 associated lipids
Macular Edema D008269 3 associated lipids
Hydatidiform Mole D006828 3 associated lipids
Contusions D003288 3 associated lipids
Yang Deficiency D016711 3 associated lipids
Aortic Rupture D001019 3 associated lipids
Hemorrhagic Fever with Renal Syndrome D006480 3 associated lipids
Bronchopulmonary Sequestration D001998 3 associated lipids
Airway Remodeling D056151 3 associated lipids
Chest Pain D002637 4 associated lipids
Chediak-Higashi Syndrome D002609 4 associated lipids
Heart Valve Diseases D006349 4 associated lipids
Streptococcal Infections D013290 4 associated lipids
Retinal Diseases D012164 4 associated lipids
Leiomyosarcoma D007890 4 associated lipids
Thromboangiitis Obliterans D013919 4 associated lipids
Embolism, Fat D004620 4 associated lipids
Bronchopulmonary Dysplasia D001997 4 associated lipids
Per page 10 20 50 100 | Total 293

PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

Download all related citations
Per page 10 20 50 100 | Total 6367
Authors Title Published Journal PubMed Link
Guerrero MD et al. Anti-inflammatory and analgesic activity of a novel inhibitor of microsomal prostaglandin E synthase-1 expression. 2009 Eur. J. Pharmacol. pmid:19686718
Hu Y et al. Chinese herbal medicinal ingredients inhibit secretion of IL-6, IL-8, E-selectin and TXB2 in LPS-induced rat intestinal microvascular endothelial cells. 2009 Immunopharmacol Immunotoxicol pmid:19874221
Dietrich-Muszalska A and Olas B Isoprostenes as indicators of oxidative stress in schizophrenia. 2009 World J. Biol. Psychiatry pmid:19673085
Lowe FJ et al. Evaluation of biomarkers of exposure and potential harm in smokers, former smokers and never-smokers. 2009 Clin. Chem. Lab. Med. pmid:19676143
Stanke-Labesque F et al. Increased urinary leukotriene E4 excretion in obstructive sleep apnea: effects of obesity and hypoxia. 2009 J. Allergy Clin. Immunol. pmid:19596146
Huntjens DR et al. Differences in the sensitivity of behavioural measures of pain to the selectivity of cyclo-oxygenase inhibitors. 2009 Eur J Pain pmid:18774319
Correa JA et al. Virgin olive oil polyphenol hydroxytyrosol acetate inhibits in vitro platelet aggregation in human whole blood: comparison with hydroxytyrosol and acetylsalicylic acid. 2009 Br. J. Nutr. pmid:18775097
Hynninen VV et al. Oral voriconazole and miconazole oral gel produce comparable effects on the pharmacokinetics and pharmacodynamics of etoricoxib. 2009 Eur. J. Clin. Pharmacol. pmid:18777173
Muir AR et al. Assessment of aspirin resistance varies on a temporal basis in patients with ischaemic heart disease. 2009 Heart pmid:18697805
Foudi N et al. Selective cyclooxygenase-2 inhibition directly increases human vascular reactivity to norepinephrine during acute inflammation. 2009 Cardiovasc. Res. pmid:18952694
Rogers LK et al. Differential responses in the lungs of newborn mouse pups exposed to 85% or >95% oxygen. 2009 Pediatr. Res. pmid:18703992
Fernández-Arche A et al. Long-chain fatty alcohols from pomace olive oil modulate the release of proinflammatory mediators. 2009 J. Nutr. Biochem. pmid:18555679
Chen SS et al. Elevated plasma prostaglandins and acetylated histone in monocytes in Type 1 diabetes patients. 2009 Diabet. Med. pmid:19236624
Kanazawa S et al. Effect of low-dose aspirin for skin rash associated with erlotinib therapy in patients with lung cancer. 2009 Platelets pmid:19172526
Calapai G et al. Cardiovascular biomarkers in groups of established smokers after a decade of smoking. 2009 Basic Clin. Pharmacol. Toxicol. pmid:19175368
Kapetanovic IM et al. Comparison of pharmacokinetic and pharmacodynamic profiles of aspirin following oral gavage and diet dosing in rats. 2009 Chem. Biol. Interact. pmid:18992230
Seta F et al. Renal and cardiovascular characterization of COX-2 knockdown mice. 2009 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:19357295
Pettinella C et al. Cyclooxygenase-1 haplotype C50T/A-842G does not affect platelet response to aspirin. 2009 Thromb. Haemost. pmid:19350112
Guagnano MT et al. Determinants of platelet activation in hypertensives with microalbuminuria. 2009 Free Radic. Biol. Med. pmid:19280705
Lo HM et al. 2'-Ethoxy-5'-methoxy-2-(5-methylthienyl)chalcone inhibits collagen-induced protein tyrosine phosphorylation and thromboxane formation during platelet aggregation and adhesion. 2009 Pharmacology pmid:19690443
Struthmann L et al. Prothrombotic effects of diclofenac on arteriolar platelet activation and thrombosis in vivo. 2009 J. Thromb. Haemost. pmid:19691487
Omura Y et al. Severe asthma with markedly increased asbestos of 2 types & TXB2, and markedly reduced acetylcholine, DHEA & drug uptake in parts of upper lungs, & similar abnormalities at respiratory & cardiac center of medulla oblongata: complete elimination of this asthma within 15 days using one optimal dose of astragalus & application of strong red light & EMF neutralizer on respiratory centers of abnormal medulla oblongata. 2009 Acupunct Electrother Res pmid:19711774
Lauring B et al. Laropiprant in combination with extended-release niacin does not alter urine 11-dehydrothromboxane B2, a marker of in vivo platelet function, in healthy, hypercholesterolemic, and diabetic subjects. 2009 J Clin Pharmacol pmid:19833861
Eriksson AC et al. Static platelet adhesion, flow cytometry and serum TXB2 levels for monitoring platelet inhibiting treatment with ASA and clopidogrel in coronary artery disease: a randomised cross-over study. 2009 J Transl Med pmid:19508722
Cattaneo M Letter by cattaneo regarding article, "incomplete inhibition of thromboxane biosynthesis by acetylsalicylic Acid: determinants and effect on cardiovascular risk". 2009 Circulation pmid:19546394
Schiff M et al. Platelet inhibitory effects of OTC doses of naproxen sodium compared with prescription dose naproxen sodium and low-dose aspirin. 2009 Curr Med Res Opin pmid:19678751
Cook VL et al. Effect of firocoxib or flunixin meglumine on recovery of ischemic-injured equine jejunum. 2009 Am. J. Vet. Res. pmid:19645580
Blais N et al. Response to aspirin in healthy individuals. Cross-comparison of light transmission aggregometry, VerifyNow system, platelet count drop, thromboelastography (TEG) and urinary 11-dehydrothromboxane B(2). 2009 Thromb. Haemost. pmid:19652893
Zhang X et al. Effect of baicalin on inflammatory mediator levels and microcirculation disturbance in rats with severe acute pancreatitis. 2009 Pancreas pmid:19657312
Liu FC et al. A new insight of anti-platelet effects of sirtinol in platelets aggregation via cyclic AMP phosphodiesterase. 2009 Biochem. Pharmacol. pmid:19426675
Li L et al. The anti-inflammatory effects of ZLJ-6, a novel dual cyclooxygenase/5-lipoxygenase inhibitor. 2009 Eur. J. Pharmacol. pmid:19243697
Peng CY et al. Dietary soy protein selectively reduces renal prostanoids and cyclooxygenases in polycystic kidney disease. 2009 Exp. Biol. Med. (Maywood) pmid:19429858
Li H et al. [Effect of an integrative medical regimen on levels of vascular endothelial function and hypersensitive C-reactive protein in elderly patients with isolated systolic hypertension]. 2009 Zhongguo Zhong Xi Yi Jie He Za Zhi pmid:19382469
Csányi G et al. Effects of 3-aminopyridine-induced seizures on platelet eicosanoid synthesis. 2008 May-Jun Pharmacol Rep pmid:18622059
Kaneko I et al. Prostaglandin F(2alpha) regulates cytokine responses of mast cells through the receptors for prostaglandin E. 2008 Biochem. Biophys. Res. Commun. pmid:18190789
Parsons JP et al. Airway inflammation in exercise-induced bronchospasm occurring in athletes without asthma. 2008 J Asthma pmid:18569228
Natarajan G et al. Chorioamnionitis and ontogeny of circulating prostaglandin and thromboxane in preterm infants. 2008 Am J Perinatol pmid:18726836
Santilli F et al. Circulating endothelial progenitor cells and residual in vivo thromboxane biosynthesis in low-dose aspirin-treated polycythemia vera patients. 2008 Blood pmid:18541722
Mitsopoulos P et al. Effectiveness of liposomal-N-acetylcysteine against LPS-induced lung injuries in rodents. 2008 Int J Pharm pmid:18694812
Yokoyama Y et al. Up-regulated thromboxane production in the rat liver with biliary obstruction does not contribute to promote hepatic injury. 2008 Shock pmid:17885643
Aslam R et al. Lipoproteins inhibit platelet aggregation and arachidonic acid metabolism in experimental hypercholesterolaemia. 2008 Clin. Exp. Pharmacol. Physiol. pmid:18215184
Toscano CD et al. NMDA-induced seizure intensity is enhanced in COX-2 deficient mice. 2008 Neurotoxicology pmid:18834901
Lee CR et al. Cyclooxygenase polymorphisms and risk of cardiovascular events: the Atherosclerosis Risk in Communities (ARIC) study. 2008 Clin. Pharmacol. Ther. pmid:17495879
Park MK et al. Antiplatelet and antithrombotic activity of indole-3-carbinol in vitro and in vivo. 2008 Phytother Res pmid:17724769
Helgason CM et al. Platelet aggregation and recruitment with aspirin-clopidogrel therapy. 2008 Cerebrovasc. Dis. pmid:18349532
Momen A et al. Local prostaglandin blockade attenuates muscle mechanoreflex-mediated renal vasoconstriction during muscle stretch in humans. 2008 Am. J. Physiol. Heart Circ. Physiol. pmid:18326807
Skoglund C et al. C-reactive protein and C1q regulate platelet adhesion and activation on adsorbed immunoglobulin G and albumin. 2008 Immunol. Cell Biol. pmid:18332893
Menzies D et al. Effect of aspirin on airway inflammation and pulmonary function in patients with persistent asthma. 2008 J. Allergy Clin. Immunol. pmid:18313127
Hasan J et al. Early postnatal ibuprofen and indomethacin effects in suckling and weanling rat kidneys. 2008 Prostaglandins Other Lipid Mediat. pmid:18096423
Ruan KH et al. An active triple-catalytic hybrid enzyme engineered by linking cyclo-oxygenase isoform-1 to prostacyclin synthase that can constantly biosynthesize prostacyclin, the vascular protector. 2008 FEBS J. pmid:19021758