Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Body Weight D001835 333 associated lipids
Lung Neoplasms D008175 171 associated lipids
Adenocarcinoma D000230 166 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Edema D004487 152 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Hemolysis D006461 131 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Inflammation D007249 119 associated lipids
Hypertension D006973 115 associated lipids
Glioma D005910 112 associated lipids
Weight Gain D015430 101 associated lipids
Hypercholesterolemia D006937 91 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Brain Ischemia D002545 89 associated lipids
Seizures D012640 87 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Arteriosclerosis D001161 86 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Atherosclerosis D050197 85 associated lipids
Stomach Ulcer D013276 75 associated lipids
Hyperlipidemias D006949 73 associated lipids
Carcinoma, Non-Small-Cell Lung D002289 72 associated lipids
Coronary Disease D003327 70 associated lipids
Colitis D003092 69 associated lipids
Liver Cirrhosis D008103 67 associated lipids
Mammary Neoplasms, Experimental D008325 67 associated lipids
Reperfusion Injury D015427 65 associated lipids
Pain D010146 64 associated lipids
Weight Loss D015431 56 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Asthma D001249 52 associated lipids
Leukemia, Myeloid D007951 52 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Thrombosis D013927 49 associated lipids
Fatty Liver D005234 48 associated lipids
Coronary Artery Disease D003324 47 associated lipids
Metabolic Syndrome D024821 44 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Ischemic Attack, Transient D002546 42 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Hyperalgesia D006930 42 associated lipids
Arthritis D001168 41 associated lipids
Hypotension D007022 41 associated lipids
Diabetic Nephropathies D003928 39 associated lipids
Diabetic Retinopathy D003930 39 associated lipids
Zellweger Syndrome D015211 39 associated lipids
Lung Diseases D008171 37 associated lipids
Liver Cirrhosis, Experimental D008106 36 associated lipids
Heart Failure D006333 36 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

Download all related citations
Per page 10 20 50 100 | Total 6367
Authors Title Published Journal PubMed Link
Davì G et al. Diabetes mellitus, hypercholesterolemia, and hypertension but not vascular disease per se are associated with persistent platelet activation in vivo. Evidence derived from the study of peripheral arterial disease. 1997 Circulation pmid:9236419
Rautanen M et al. Experimental fat embolism induces urine 2,3-dinor-6-ketoprostaglandin F1alpha and 11-dehydrothromboxane B2 excretion in pigs. 1997 Crit. Care Med. pmid:9233750
Desideri N et al. N-omega-carbethoxypentyl-4-quinolones: a new class of leukotriene biosynthesis inhibitors. 1997 Arch. Pharm. (Weinheim) pmid:9230527
Calzada C et al. Low concentrations of lipid hydroperoxides prime human platelet aggregation specifically via cyclo-oxygenase activation. 1997 Biochem. J. pmid:9230133
Hansen TN and Brockbank KG Increased platelet aggregation due to chilling to 20 degrees C is not related to increased sensitivity to agonists. 1997 Transfusion pmid:9225932
Inui Y et al. Platelet volume and urinary prostanoid metabolites in non-insulin-dependent diabetes mellitus. 1994 J. Atheroscler. Thromb. pmid:9222878
Matsumata T et al. Urinary excretion of prostaglandins and renal function after hepatic resection. 1997 May-Jun Hepatogastroenterology pmid:9222688
De la Cruz JP et al. Effect of erythrocytes and prostacyclin production in the effect of fructose and sorbitol on platelet activation in human whole blood in vitro. 1997 Thromb. Res. pmid:9219331
Fenner H Differentiating among nonsteroidal antiinflammatory drugs by pharmacokinetic and pharmacodynamic profiles. 1997 Semin. Arthritis Rheum. pmid:9219317
Ansley DM et al. Platelet activating factor and thromboxane B2 production after cardiopulmonary bypass. 1997 May-Jun J Invest Surg pmid:9219083
Malini PL et al. Thromboxane antagonism and cough induced by angiotensin-converting-enzyme inhibitor. 1997 Lancet pmid:9217714
Nanji AA et al. Cholesterol supplementation prevents necrosis and inflammation but enhances fibrosis in alcoholic liver disease in the rat. 1997 Hepatology pmid:9214456
Yan Y et al. [Study on mechanism of eye-signs in blood stasis syndrome]. 1996 Zhongguo Zhong Xi Yi Jie He Za Zhi pmid:9206243
Hellyer PW et al. Effect of NG-nitro-L-arginine-methyl-ester on cardiopulmonary function and biosynthesis of cyclooxygenase products during porcine endotoxemia. 1997 Crit. Care Med. pmid:9201060
Carty TJ et al. Tenidap inhibits 5-lipoxygenase product formation in vitro, but this activity is not observed in three animal models. 1997 Inflamm. Res. pmid:9197987
Hato T et al. Outside-in signaling from integrin alpha IIb beta 3 into platelets in the absence of agonist-induced signaling. 1997 Int. J. Hematol. pmid:9195778
Cook ME et al. Comparative effects of nabumetone, sulindac, and ibuprofen on renal function. 1997 J. Rheumatol. pmid:9195523
Fujinishi A et al. Effects of nisoldipine on cytosolic calcium, platelet aggregation, and coagulation/fibrinolysis in patients with coronary artery disease. 1997 Angiology pmid:9194537
Ali M et al. Synthesis of prostaglandin D2 and thromboxane B2 by human platelets. 1977 Thromb. Res. pmid:918907
Oosaki R et al. Urinary leukotriene E4 and 11-dehydrothromboxane B2 in patients with aspirin-sensitive asthma. 1997 Allergy pmid:9188934