Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Body Weight D001835 333 associated lipids
Lung Neoplasms D008175 171 associated lipids
Adenocarcinoma D000230 166 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Edema D004487 152 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Hemolysis D006461 131 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Inflammation D007249 119 associated lipids
Hypertension D006973 115 associated lipids
Glioma D005910 112 associated lipids
Weight Gain D015430 101 associated lipids
Hypercholesterolemia D006937 91 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Brain Ischemia D002545 89 associated lipids
Seizures D012640 87 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Arteriosclerosis D001161 86 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Atherosclerosis D050197 85 associated lipids
Stomach Ulcer D013276 75 associated lipids
Hyperlipidemias D006949 73 associated lipids
Carcinoma, Non-Small-Cell Lung D002289 72 associated lipids
Coronary Disease D003327 70 associated lipids
Colitis D003092 69 associated lipids
Mammary Neoplasms, Experimental D008325 67 associated lipids
Liver Cirrhosis D008103 67 associated lipids
Reperfusion Injury D015427 65 associated lipids
Pain D010146 64 associated lipids
Weight Loss D015431 56 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Leukemia, Myeloid D007951 52 associated lipids
Asthma D001249 52 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Thrombosis D013927 49 associated lipids
Fatty Liver D005234 48 associated lipids
Coronary Artery Disease D003324 47 associated lipids
Metabolic Syndrome D024821 44 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Ischemic Attack, Transient D002546 42 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Hyperalgesia D006930 42 associated lipids
Hypotension D007022 41 associated lipids
Arthritis D001168 41 associated lipids
Zellweger Syndrome D015211 39 associated lipids
Diabetic Nephropathies D003928 39 associated lipids
Diabetic Retinopathy D003930 39 associated lipids
Lung Diseases D008171 37 associated lipids
Liver Cirrhosis, Experimental D008106 36 associated lipids
Heart Failure D006333 36 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

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Per page 10 20 50 100 | Total 6367
Authors Title Published Journal PubMed Link
Simmons PM et al. The release of leukotriene B4 during experimental inflammation. 1983 Biochem. Pharmacol. pmid:6305369
Mäkilä UM et al. Relation between umbilical prostacyclin production and blood-flow in the fetus. 1983 Lancet pmid:6132081
Thorngren M et al. Thromboxane A2 in skin-bleeding-time blood and in clotted venous blood before and after administration of acetylsalicylic acid. 1983 Lancet pmid:6133107
Drake TS et al. Peritoneal fluid prostanoids in unexplained infertility. 1983 Am. J. Obstet. Gynecol. pmid:6614085
Stenson WF and Lobos E Inhibition of platelet thromboxane synthetase by sulfasalazine. 1983 Biochem. Pharmacol. pmid:6135423
Chang J et al. Effects of thiazinamium chloride, promethazine and chlorpromazine on thromboxane B2 synthesis, phagocytosis and respiratory burst by rat alveolar macrophages. 1983 Biochem. Pharmacol. pmid:6138040
Deckmyn H et al. Manipulation of the local thromboxane and prostacyclin balance in vivo by the antithrombotic compounds dazoxiben, acetylsalicylic acid and nafazatrom. 1983 Biochem. Pharmacol. pmid:6578796
Goetzl EJ et al. Enhancement of human neutrophil adherence by synthetic leukotriene constituents of the slow-reacting substance of anaphylaxis. 1983 Immunology pmid:6193056
McManus LM et al. Thromboxane B2 (TxB2) release following acetyl glyceryl ether phosphorylcholine (AGEPC) infusion in the rabbit. 1983 Immunopharmacology pmid:6832960
Martin JL et al. Effect of atrial pacing on intracoronary thromboxane production in coronary artery disease. 1983 J. Am. Coll. Cardiol. pmid:6833660
Ferraris VA and Swanson E Aspirin usage and perioperative blood loss in patients undergoing unexpected operations. 1983 Surg Gynecol Obstet pmid:6836459
Margotat A et al. A rapid and simple assay for the study of thromboxane B2 synthesis by intact human platelets. 1983 J Pharmacol Methods pmid:6843139
Rotmensch HH et al. Plasma platelet products and exercise-induced myocardial ischemia. 1983 J. Lab. Clin. Med. pmid:6854135
Palmer RM and Salmon JA Release of leukotriene B4 from human neutrophils and its relationship to degranulation induced by N-formyl-methionyl-leucyl-phenylalanine, serum-treated zymosan and the ionophore A23187. 1983 Immunology pmid:6309653
Ditter H et al. Effects of prostacyclin during cardiopulmonary bypass in men on plasma levels of beta-thromboglobulin, platelet factor 4, thromboxane B2, 6-keto-prostaglandin F1 alpha and heparin. 1983 Thromb. Res. pmid:6197766
Kangasaho M et al. Formation of thromboxane B2 by platelets and concentrations of thromboxane B2 and 6-keto-prostaglandin F1 alpha in plasma after acute ethanol ingestion. 1983 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:6303086
Samuelsson B From studies of biochemical mechanism to novel biological mediators: prostaglandin endoperoxides, thromboxanes, and leukotrienes. Nobel Lecture, 8 December 1982. 1983 Biosci. Rep. pmid:6315101
Lismonde M et al. [The presence of 6-oxo-PGF1alpha and thromboxane B2 in peritoneal exudates released by iota-carrageenan in the rat]. 1983 Arch. Int. Physiol. Biochim. pmid:6198994
Gorman RR et al. Inhibition of platelet thromboxane A2 synthase activity by sodium 5-(3'-pyridinylmethyl)benzofuran-2-carboxylate. 1983 Prostaglandins pmid:6316421
Salmon JA et al. Synthesis of arachidonate cyclo-oxygenase products by rheumatoid and nonrheumatoid synovial lining in nonproliferative organ culture. 1983 Ann. Rheum. Dis. pmid:6402992
Bloch MH et al. Prostaglandin production by the pregnant and non-pregnant rabbit uterus. 1983 Prostaglandins pmid:6415760
McDaniel HG et al. Platelet function abnormalities in response to arachidonic acid in the acute phase of myocardial infarction. 1983 Am. J. Cardiol. pmid:6416046
Marcella JJ et al. Exercise-induced myocardial ischemia in patients with coronary artery disease: lack of evidence for platelet activation or fibrin formation in peripheral venous blood. 1983 J. Am. Coll. Cardiol. pmid:6339591
Brox JH et al. Effects of cod liver oil on platelets and coagulation in familial hypercholesterolemia (type IIa). 1983 Acta Med Scand pmid:6340424
Mest HJ et al. The influence of linseed oil diet on fatty acid pattern in phospholipids and thromboxane formation in platelets in man. 1983 Klin. Wochenschr. pmid:6341702
Hartung HP et al. Stimulation of prostaglandin E and thromboxane synthesis in macrophages by purified C3b. 1983 J. Immunol. pmid:6343486
Deckmyn H et al. Prostacyclin production by whole blood from children: impairment in the hemolytic uremic syndrome and excessive formation in chronic renal failure. 1983 Thromb. Res. pmid:6344317
Ylikorkala O and Viinikka L Prostaglandins and endometriosis. 1983 Acta Obstet Gynecol Scand Suppl pmid:6344540
Ylikorkala O Prostacyclin and thromboxane during human pregnancy. 1983 Acta Obstet Gynecol Scand Suppl pmid:6344543
Qvist R and Larkins RG Diminished production of thromboxane B2 and prostaglandin E by stimulated polymorphonuclear leukocytes from insulin-treated diabetic subjects. 1983 Diabetes pmid:6345241
Newman JH et al. Effects of 100% oxygen on lung vascular function in awake sheep. 1983 J Appl Physiol Respir Environ Exerc Physiol pmid:6345493
Eldor A et al. Effects of dipyrone on prostaglandin production by human platelets and cultured bovine aortic endothelial cells. 1983 Thromb. Haemost. pmid:6346571
Sheng WY et al. Kinetic comparison and regulation of the cascade of microsomal enzymes involved in renal arachidonate and endoperoxide metabolism. 1983 J. Biol. Chem. pmid:6401732
Menys VC and Davies JA Selective inhibition of thromboxane synthetase with dazoxiben - basis of its inhibitory effect on platelet adhesion. 1983 Thromb. Haemost. pmid:6346575
Reeves WC et al. The release of thromboxane A2 and prostacyclin following experimental acute pulmonary embolism. 1983 Prostaglandins Leukot Med pmid:6348800
Aznavoorian SA et al. Prostacyclin inhibits 5-hydroxytryptamine release but stimulates thromboxane synthesis during cardiopulmonary bypass. 1983 Prostaglandins pmid:6348886
Buchanan MR et al. The sex-related differences in aspirin pharmacokinetics in rabbits and man and its relationship to antiplatelet effects. 1983 Thromb. Res. pmid:6221436
Yamamoto S et al. Enzyme immunoassay of thromboxane B2 and 6-keto-prostaglandin F1 alpha as a substitute for radioimmunoassay. 1983 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:6221523
Weerasekera DA et al. Chemiluminescence immunoassay of thromboxane B2. 1983 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:6221524
Kawaguchi H Thromboxane synthesis in hypercholesterolemic platelets--on the mechanism of increased thromboxane synthesis. 1983 Hokkaido Igaku Zasshi pmid:6618425
Ito T et al. Effects of a selective inhibitor of thromboxane synthetase (OKY-1581) in humans. 1983 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:6221531
FitzGerald GA et al. Aspirin inhibits endogenous prostacyclin and thromboxane biosynthesis in man. 1983 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:6221534
Dubin NH et al. Thromboxane production in the pregnant rat: differential recovery by platelets and uterus following aspirin administration. 1983 Biol. Reprod. pmid:6626652
van der Giessen WJ et al. Acute effect of cigarette smoking on cardiac prostaglandin synthesis and platelet behavior in patients with coronary heart disease. 1983 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:6221546
Nuotto E et al. Effect of acetylsalicylic acid on plasma thromboxane B2 and platelet aggregation in man. 1983 Eur. J. Clin. Pharmacol. pmid:6628518
Bach MK et al. In vivo and in vitro actions of a new selective inhibitor of leukotriene C and D synthesis. 1983 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:6221551
Grose JH et al. Imbalanced prostacyclin and thromboxane A2 production in essential hypertension. 1983 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:6221555
Hornych A et al. Thromboxane B2 in borderline and essential hypertension. 1983 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:6221556
MacIntyre DE et al. Role of endogenous arachidonate metabolites in phospholipid-induced human platelet activation. 1983 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:6221557
Kiff PS et al. Haemodynamic and metabolic effects of dazoxiben at rest and during atrial pacing. 1983 Br J Clin Pharmacol pmid:6681708
Hutton I et al. Effects of dazoxiben on transcardiac thromboxane levels and haemodynamics in coronary heart disease. 1983 Br J Clin Pharmacol pmid:6681709
Zijlstra FJ et al. Thrombotic thrombocytopenic purpura and plasma thromboxane B2 levels. 1983 Thromb. Res. pmid:6684333
Abiko Y et al. The stimulation of macrophage prostaglandin E2 and thromboxane B2 secretion by Streptococcus mutans insoluble glucans. 1983 FEBS Lett. pmid:6403385
Morita I et al. Stimulation of eicosapentaenoic acid metabolism in washed human platelets by 12-hydroperoxyeicosatetraenoic acid. 1983 J. Biol. Chem. pmid:6309794
Gordon PR et al. Platelet arachidonate metabolism and platelet function in zinc-deficient rats. 1983 J. Nutr. pmid:6403678
Okegawa T et al. Endotoxin induces chronic prostaglandin and thromboxane synthesis from ureter-obstructed kidneys: role of inflammatory cells. 1983 J. Pharmacol. Exp. Ther. pmid:6403696
Han P et al. Verapamil and collagen-induced platelet reactions--evidence for a role for intracellular calcium in platelet activation. 1983 Thromb. Haemost. pmid:6415847
Barnhart MI et al. DDAVP: does the drug have a direct effect on the vessel wall? 1983 Thromb. Res. pmid:6415852
Wallis RB Mechanisms of action of sulphinpyrazone. 1983 Thromb. Res. Suppl. pmid:6415857
Di Minno G et al. Monitoring the entry of new platelets into the circulation after ingestion of aspirin. 1983 Blood pmid:6404326
Gurtner GH et al. Oxidant- and lipid-induced pulmonary vasoconstriction mediated by arachidonic acid metabolites. 1983 J Appl Physiol Respir Environ Exerc Physiol pmid:6688802
van Rijk GL et al. Long-term myocardial preservation: thromboxane production and coronary resistance. 1983 J. Surg. Res. pmid:6688844
Miller JB et al. Alterations in plasma and tissue prostaglandin levels in rabbits during luteal regression. 1983 Biol. Reprod. pmid:6688954
Hidaka T et al. Thromboxane formation from arachidonic acid and prostaglandin H2 in rabbit spleen. 1983 J. Biochem. pmid:6404897
Davì G et al. The effect of two low doses of aspirin on whole blood thromboxane and prostacyclin generation in healthy subjects. 1983 Thromb. Haemost. pmid:6417815
Muccitelli RM et al. Effect of inhibition of thromboxane production on the leukotriene D4-mediated bronchoconstriction in the guinea pig. 1983 Prostaglandins pmid:6689082
Gerozissis K and Dray F In-vitro prostanoid production by the rat vas deferens. 1983 J. Reprod. Fertil. pmid:6572721
Dale J et al. The effect of a thromboxane synthetase inhibitor, dazoxiben, and acetylsalicylic acid on platelet function and prostaglandin metabolism. 1983 Thromb. Haemost. pmid:6689091
Schleimer RP et al. Effects of dexamethasone on mediator release from human lung fragments and purified human lung mast cells. 1983 J. Clin. Invest. pmid:6134755
Liu J [Effect of Paeonia obovata 801 on metabolism of thromboxane B2 and arachidonic acid and on platelet aggregation in patients with coronary heart disease and cerebral thrombosis]. 1983 Zhonghua Yi Xue Za Zhi pmid:6418338
Aehringhaus U et al. Effect of inhibition of synthesis and receptor antagonism of SRS-A in cardiac anaphylaxis. 1983 Br. J. Pharmacol. pmid:6689134
Kurata M [Relation between mouse peritoneal macrophage functions and prostaglandins]. 1983 Rinsho Byori pmid:6689184
Maguire ED and Wallis RB In vivo redirection of prostaglandin endoperoxides into 6-keto PGF1 alpha formation by thromboxane synthetase inhibitors in the rat. 1983 Thromb. Res. pmid:6689221
McDonald JW and Ali M Recovery of cyclooxygenase activity after aspirin in populations of platelets separated on stractan density gradients. 1983 Prostaglandins Leukot Med pmid:6419234
Zijlstra FJ and Vincent JE Comparison of the determination of thromboxane A2 by bioassay on the rabbit mesenteric artery and in the form of TxB2 by radioimmunoassay. 1983 J Pharmacol Methods pmid:6632924
Bryant RW and Hwang DH Development of a radioimmunoassay for 15-HETE and its application to 15-HETE production by reticulocytes. 1983 Prostaglandins pmid:6419285
Wilson L Effects of estradiol and progesterone on uterine prostaglandin levels in the pregnant rat. 1983 Prostaglandins pmid:6635211
Sanders TA and Hochland MC A comparison of the influence on plasma lipids and platelet function of supplements of omega 3 and omega 6 polyunsaturated fatty acids. 1983 Br. J. Nutr. pmid:6639916
Mehta JL Prostaglandins: regulatory role in cardiovascular system and implications in ischemic heart disease. 1983 Int. J. Cardiol. pmid:6642760
Chong KP et al. Vasopressin stimulates thromboxane synthesis in isolated hamster hepatocytes: relation to hepatocyte calcium content. 1983 Prostaglandins pmid:6419286
Hartung HP et al. Induction of thromboxane release from macrophages by anaphylatoxic peptide C3a of complement and synthetic hexapeptide C3a 72-77. 1983 J. Immunol. pmid:6600482
Sautebin L et al. Preferential utilization of endogenous arachidonate by cyclo-oxygenase in incubations of human platelets. 1983 FEBS Lett. pmid:6407867
Zipser RD et al. Urinary thromboxane B2 and prostaglandin E2 in the hepatorenal syndrome: evidence for increased vasoconstrictor and decreased vasodilator factors. 1983 Gastroenterology pmid:6572162
Schenkelaars EJ and Bonta IL Effect of leukotriene C4 on the release of secretory products by elicited populations of rat peritoneal macrophages. 1983 Eur. J. Pharmacol. pmid:6572592
Rocklin RE et al. Augmentation of prostaglandin and thromboxane production in vitro by monocytes exposed to histamine-induced suppressor factor (HSF). 1983 Cell. Immunol. pmid:6573232
Ouwendijk RJ et al. Raised plasma thromboxane B2 levels in alcoholic liver disease. 1983 Prostaglandins Leukot Med pmid:6573682
Hornych A et al. Thromboxane B2 in borderline and essential hypertensive patients. 1983 Prostaglandins Leukot Med pmid:6573683
Flynn JT et al. Effects of anesthesia and surgery on prostanoid concentrations in plasma and pulmonary lymph. 1983 Prostaglandins Leukot Med pmid:6573688
Patel K and Bakhle YS Thromboxane B2 (TxB2) metabolism in rat isolated lung and its inhibition by drugs. 1983 Prostaglandins Leukot Med pmid:6573689
Davì G et al. Plasmatic TXB2 and 6-keto-PGF1 alpha levels during charcoal hemoperfusion in chronic renal failure patients. 1983 Prostaglandins Leukot Med pmid:6573692
Lieb J et al. Elevated levels of prostaglandin E2 and thromboxane B2 in depression. 1983 Prostaglandins Leukot Med pmid:6574523
Okahara T et al. Zonal heterogeneity of prostaglandin and thromboxane release in the dog kidney. 1983 Prostaglandins pmid:6575405
Hoult JR and Robinson C Selective inhibition of thromboxane B2 accumulation and metabolism in perfused guinea-pig lung. 1983 Br. J. Pharmacol. pmid:6824820
Hirsh PD et al. Effects of provocation on transcardiac thromboxane in patients with coronary artery disease. 1983 Am. J. Cardiol. pmid:6829431
Walinsky P et al. Beneficial effects of ibuprofen in pacing-induced myocardial ischemia. 1983 Am. J. Cardiol. pmid:6829434
Gimenez T et al. Fetal-maternal secretion of prostaglandins in the cow. 1983 Prostaglandins pmid:6576447
Butler RR et al. Gentamicin and indomethacin in the treatment of septic shock: effects on prostacyclin and thromboxane A2 production. 1983 J. Pharmacol. Exp. Ther. pmid:6339712
Laitinen O et al. Plasma levels and urinary excretion of prostaglandins in patients with rheumatoid arthritis. 1983 Clin. Rheumatol. pmid:6589104
Ouwendijk RJ et al. Raised plasma levels of thromboxane B2 in systemic mastocytosis. 1983 Eur. J. Clin. Invest. pmid:6409646
Snapper JR et al. Effects of cyclooxygenase inhibitors on the alterations in lung mechanics caused by endotoxemia in the unanesthetized sheep. 1983 J. Clin. Invest. pmid:6409930