Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Schelzig H et al. | Role of recombinant hirudin in a pig-to-human lung transplantation model. | 2002 | Transplant. Proc. | pmid:12270449 |
López-Boado MA et al. | Free radical ablation prevents ischemic injury after long periods of cold storage in rat pancreas transplantation. | 1990 | Transplant. Proc. | pmid:2219357 |
Anderson CB et al. | Thromboxane-B2 and renovascular resistance during hypothermic pulsatile perfusion. | 1981 | Transplant. Proc. | pmid:7268892 |
Odor-Morales A et al. | In vivo thromboxane production by different organs in the rat: its implication in organ transplant failure. | 1987 | Transplant. Proc. | pmid:3617213 |
Kanji VK et al. | Vitamin E suppresses cyclosporine A-induced increase in the urinary excretion of arachidonic acid metabolites including F2-isoprostanes in the rat model. | 1999 | Transplant. Proc. | pmid:10331052 |
GarcÃa-Valdecasas JC et al. | Prostaglandin metabolism and hemodynamic alterations during human liver transplantation. | 1993 | Transplant. Proc. | pmid:8470202 |
Uchiyama M et al. | Comparison between nonpulsatile and pulsatile machine perfusion preservation in liver transplantation from non-heart-beating donors. | 2001 Feb-Mar | Transplant. Proc. | pmid:11267136 |
Norio K et al. | Eicosanoids and delayed graft function in human renal transplantation. | 2001 | Transplant. Proc. | pmid:11406239 |
WÅ‚odarczyk Z et al. | Effects of pentoxifylline treatment on delayed graft function in cadaveric kidney recipients. | 2000 | Transplant. Proc. | pmid:10995988 |
Schultze G et al. | Effect of cyclosporine on the generation of prostanoids by cultured peripheral lymphocytes. | 1984 | Transplant. Proc. | pmid:6592863 |
Nakache R et al. | Pancreatic juice immunoreactive thromboxane B2 in pancreas allograft rejection. | 1990 | Transplant. Proc. | pmid:1691546 |
Odor-Morales A et al. | Urinary amylase, urinary insulin, or urinary thromboxane: which is the best predictor of pancreatic allograft rejection in the dog? | 1990 | Transplant. Proc. | pmid:1691549 |
Oikawa K et al. | Elimination of Kupffer cells suppresses activation of nuclear factor kappa B and production of cytokines and eicosanoids in non-heart-beating donors. | 2001 Feb-Mar | Transplant. Proc. | pmid:11267090 |
Lim LK et al. | Fine needle aspiration biopsy, serum beta 2-microglobulin, and urine thromboxane in renal allografts. | 1989 | Transplant. Proc. | pmid:2669249 |
Odor-Morales A et al. | Urinary thromboxane B2 as indicator of pancreatic allograft rejection in nonimmunosuppressed dogs. | 1989 | Transplant. Proc. | pmid:2669272 |
Santillan-Doherty P et al. | Thromboxane B2 and lung transplantation: correlation of rejection with levels detected in bronchoalveolar lavage. | 1989 | Transplant. Proc. | pmid:2669273 |
Zhao Y et al. | Feasibility of serial fine needle aspiration biopsies to monitor dog single lung allografts. | 1989 | Transplant. Proc. | pmid:2669274 |
Foegh ML et al. | Urine thromboxane as an immunologic monitor in kidney transplant patients. | 1984 | Transplant. Proc. | pmid:6390872 |
Foegh ML et al. | Monitoring of rat heart allograft rejection by urinary thromboxane. | 1984 | Transplant. Proc. | pmid:6390873 |
Kagawa K et al. | Prolongation of rat cardiac allograft survival with arachidonic acid metabolism inhibitor. | 1987 | Transplant. Proc. | pmid:3103286 |
Quereda C et al. | Urinary thromboxane B2 and cyclic AMP in cyclosporine-A-treated kidney transplantation. | 1994 | Transplant. Proc. | pmid:7940810 |
Lim LK et al. | Effect of the 5-lipoxygenase inhibitors EP 10045 and EP 10161 on cardiac graft cellular infiltrate and thromboxane formation. | 1988 | Transplant. Proc. | pmid:3284052 |
Lim LK et al. | Correlation of renal inflammatory cell infiltrate with thromboxane. | 1988 | Transplant. Proc. | pmid:3284053 |
Häyry P et al. | Role of thromboxane in the generation of allograft arteriosclerosis in chronic rejection. | 1993 | Transplant. Proc. | pmid:8438433 |
Weir MR et al. | Acute effects of intravenous cyclosporine on blood pressure, renal hemodynamics, and urine prostaglandin production of healthy humans. | 1990 | Transplantation | pmid:2301025 |
Coffman TM et al. | Effect of dietary fish oil supplementation on eicosanoid production by rat renal allografts. | 1988 | Transplantation | pmid:3125638 |
Fan TP et al. | Mechanism of action of cyclosporine in preventing cardiac allograft rejection. II. Graft tissue levels of prostacyclin and thromboxane. | 1987 | Transplantation | pmid:3547787 |
Kawaguchi A et al. | Urinary thromboxane excretion in cardiac allograft rejection in immunosuppressed rats. | 1987 | Transplantation | pmid:3547788 |
Capitanio A et al. | Detection of circulating released platelets after renal transplantation. | 1982 | Transplantation | pmid:6461116 |
Gibbons CP et al. | Cortical and vascular prostaglandin synthesis during renal allograft rejection in the rat. | 1987 | Transplantation | pmid:3554639 |
Balkhy HH et al. | Comparison of Eurocollins and University of Wisconsin solution in single flush preservation of the ischemic reperfused lung: an in vivo rabbit model. | 1995 | Transplantation | pmid:7732552 |
Markewitz A et al. | Reduction of cyclosporine-induced nephrotoxicity by cilastatin following clinical heart transplantation. | 1994 | Transplantation | pmid:8154033 |
Kim YI et al. | Hepatoprotection by a PGI2 analogue in complete warm ischemia of the pig liver. Prostanoid release from the reperfused liver. | 1994 | Transplantation | pmid:7940729 |
Textor SC et al. | Systemic and renal hemodynamic differences between FK506 and cyclosporine in liver transplant recipients. | 1993 | Transplantation | pmid:7685934 |
Petric R et al. | Amelioration of experimental cyclosporine nephrotoxicity by calcium channel inhibition. | 1992 | Transplantation | pmid:1465778 |
Johnson BF et al. | Urinary thromboxane and 6-keto-prostaglandin F1 alpha are early markers of acute rejection in experimental pancreas transplantation. | 1994 | Transplantation | pmid:7518618 |
Smith SR et al. | Chronic thromboxane synthase inhibition with CGS 12970 in human cyclosporine nephrotoxicity. | 1993 | Transplantation | pmid:8279014 |
Johnson BF et al. | Thromboxane and prostacyclin synthesis in experimental pancreas transplantation. Changes in parenchymal and vascular prostanoids. | 1993 | Transplantation | pmid:8279018 |
Proppe DG et al. | Diagnostic value of urinary thromboxane B2 concentration in detection of initial acute rejection reactions in human renal allografts. | 1995 | Transplantation | pmid:7709445 |
Youngelman DF et al. | Effects of chronic cyclosporine administration on renal blood flow and intrarenal blood flow distribution. | 1991 | Transplantation | pmid:1994546 |
Elzinga L et al. | Modification of experimental nephrotoxicity with fish oil as the vehicle for cyclosporine. | 1987 | Transplantation | pmid:3810835 |
Coffman TM et al. | Evidence that renal prostaglandin and thromboxane production is stimulated in chronic cyclosporine nephrotoxicity. | 1987 | Transplantation | pmid:3810836 |
Post S et al. | Rapid increase in the activity of enzymes of eicosanoid synthesis in hepatic and extrahepatic tissues after experimental liver transplantation. | 1991 | Transplantation | pmid:1903222 |
GarcÃa-Valdecasas JC et al. | Prostacyclin, thromboxane, and oxygen free radicals and postoperative liver function in human liver transplantation. | 1995 | Transplantation | pmid:7570973 |
Hotter G et al. | Nitric oxide and arachidonate metabolism in ischemia-reperfusion associated with pancreas transplantation. | 1995 | Transplantation | pmid:7871573 |
Moore TC et al. | Depression of peripheral lymph node lymphocyte traffic in sheep following central venous allogeneic whole-blood transfusion. | 1990 | Transplantation | pmid:1970202 |
Suckfüll MM et al. | The contribution of endothelial cells to hyperacute rejection in xenogeneic perfused working hearts. | 1994 | Transplantation | pmid:8310518 |
Post S et al. | Prostanoid release in experimental liver transplantation. | 1990 | Transplantation | pmid:2316009 |
Schnabel FR et al. | The relationship of urinary thromboxane excretion to cyclosporine nephrotoxicity. | 1991 | Transplantation | pmid:2006526 |
Ruiz P et al. | Evidence that pretransplant donor blood transfusion prevents rat renal allograft dysfunction but not the in situ cellular alloimmune or morphologic manifestations of rejection. | 1988 | Transplantation | pmid:3276038 |