Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Davì G et al. | Diabetes mellitus, hypercholesterolemia, and hypertension but not vascular disease per se are associated with persistent platelet activation in vivo. Evidence derived from the study of peripheral arterial disease. | 1997 | Circulation | pmid:9236419 |
Rautanen M et al. | Experimental fat embolism induces urine 2,3-dinor-6-ketoprostaglandin F1alpha and 11-dehydrothromboxane B2 excretion in pigs. | 1997 | Crit. Care Med. | pmid:9233750 |
Desideri N et al. | N-omega-carbethoxypentyl-4-quinolones: a new class of leukotriene biosynthesis inhibitors. | 1997 | Arch. Pharm. (Weinheim) | pmid:9230527 |
Calzada C et al. | Low concentrations of lipid hydroperoxides prime human platelet aggregation specifically via cyclo-oxygenase activation. | 1997 | Biochem. J. | pmid:9230133 |
Hansen TN and Brockbank KG | Increased platelet aggregation due to chilling to 20 degrees C is not related to increased sensitivity to agonists. | 1997 | Transfusion | pmid:9225932 |
Inui Y et al. | Platelet volume and urinary prostanoid metabolites in non-insulin-dependent diabetes mellitus. | 1994 | J. Atheroscler. Thromb. | pmid:9222878 |
Matsumata T et al. | Urinary excretion of prostaglandins and renal function after hepatic resection. | 1997 May-Jun | Hepatogastroenterology | pmid:9222688 |
De la Cruz JP et al. | Effect of erythrocytes and prostacyclin production in the effect of fructose and sorbitol on platelet activation in human whole blood in vitro. | 1997 | Thromb. Res. | pmid:9219331 |
Fenner H | Differentiating among nonsteroidal antiinflammatory drugs by pharmacokinetic and pharmacodynamic profiles. | 1997 | Semin. Arthritis Rheum. | pmid:9219317 |
Ansley DM et al. | Platelet activating factor and thromboxane B2 production after cardiopulmonary bypass. | 1997 May-Jun | J Invest Surg | pmid:9219083 |
Malini PL et al. | Thromboxane antagonism and cough induced by angiotensin-converting-enzyme inhibitor. | 1997 | Lancet | pmid:9217714 |
Nanji AA et al. | Cholesterol supplementation prevents necrosis and inflammation but enhances fibrosis in alcoholic liver disease in the rat. | 1997 | Hepatology | pmid:9214456 |
Yan Y et al. | [Study on mechanism of eye-signs in blood stasis syndrome]. | 1996 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:9206243 |
Hellyer PW et al. | Effect of NG-nitro-L-arginine-methyl-ester on cardiopulmonary function and biosynthesis of cyclooxygenase products during porcine endotoxemia. | 1997 | Crit. Care Med. | pmid:9201060 |
Carty TJ et al. | Tenidap inhibits 5-lipoxygenase product formation in vitro, but this activity is not observed in three animal models. | 1997 | Inflamm. Res. | pmid:9197987 |
Hato T et al. | Outside-in signaling from integrin alpha IIb beta 3 into platelets in the absence of agonist-induced signaling. | 1997 | Int. J. Hematol. | pmid:9195778 |
Cook ME et al. | Comparative effects of nabumetone, sulindac, and ibuprofen on renal function. | 1997 | J. Rheumatol. | pmid:9195523 |
Fujinishi A et al. | Effects of nisoldipine on cytosolic calcium, platelet aggregation, and coagulation/fibrinolysis in patients with coronary artery disease. | 1997 | Angiology | pmid:9194537 |
Ali M et al. | Synthesis of prostaglandin D2 and thromboxane B2 by human platelets. | 1977 | Thromb. Res. | pmid:918907 |
Oosaki R et al. | Urinary leukotriene E4 and 11-dehydrothromboxane B2 in patients with aspirin-sensitive asthma. | 1997 | Allergy | pmid:9188934 |