Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Snapper JR et al. | Role of endothelin in endotoxin-induced sustained pulmonary hypertension in sheep. | 1998 | Am. J. Respir. Crit. Care Med. | pmid:9445282 |
Dent G et al. | Protein kinase C inhibition enhances platelet-activating factor-induced eicosanoid production in human eosinophils. | 1998 | Am. J. Respir. Cell Mol. Biol. | pmid:9448055 |
Moore RM et al. | Effect of platelet-activating factor antagonist L-691,880 on low-flow ischemia-reperfusion injury of the large colon in horses. | 1998 Jan-Feb | Vet Surg | pmid:9449176 |
Parra T et al. | Cyclosporine A nephrotoxicity: role of thromboxane and reactive oxygen species. | 1998 | J. Lab. Clin. Med. | pmid:9452128 |
Yanagisawa H et al. | Ureteral obstruction enhances eicosanoid production in cortical and medullary tubules of rat kidneys. | 1997 | Kidney Blood Press. Res. | pmid:9453451 |
Erez E et al. | Thromboxane production in human lung during cardiopulmonary bypass: beneficial effect of aspirin? | 1998 | Ann. Thorac. Surg. | pmid:9456103 |
Chiba Y et al. | Effects of depletion of leukocytes and platelets on cardiac dysfunction after cardiopulmonary bypass. | 1998 | Ann. Thorac. Surg. | pmid:9456104 |
Hanaoka M et al. | Effect of post-treatment with granulocyte colony-stimulating factor on endotoxin-induced lung injury in sheep. | 1998 Jan-Feb | Exp. Lung Res. | pmid:9457466 |
Robbins DL et al. | Effect of anticardiolipin/beta2-glycoprotein I complexes on production of thromboxane A2 by platelets from patients with the antiphospholipid syndrome. | 1998 | J. Rheumatol. | pmid:9458202 |
Forastiero R et al. | Anti-beta2 glycoprotein I antibodies and platelet activation in patients with antiphospholipid antibodies: association with increased excretion of platelet-derived thromboxane urinary metabolites. | 1998 | Thromb. Haemost. | pmid:9459320 |