Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Düsing R et al. | Dietary linoleic acid deprivation: effects on blood pressure and PGI2 synthesis. | 1983 | Am. J. Physiol. | pmid:6337507 |
Saldeen P et al. | Increased synthesis of thromboxane B2 and 6-keto-PGF1 alpha in hand veins from patients with deep venous thrombosis. | 1983 | Thromb. Res. | pmid:6658723 |
McManus LM et al. | Thromboxane B2 (TxB2) release following acetyl glyceryl ether phosphorylcholine (AGEPC) infusion in the rabbit. | 1983 | Immunopharmacology | pmid:6832960 |
Martin JL et al. | Effect of atrial pacing on intracoronary thromboxane production in coronary artery disease. | 1983 | J. Am. Coll. Cardiol. | pmid:6833660 |
Ferraris VA and Swanson E | Aspirin usage and perioperative blood loss in patients undergoing unexpected operations. | 1983 | Surg Gynecol Obstet | pmid:6836459 |
Margotat A et al. | A rapid and simple assay for the study of thromboxane B2 synthesis by intact human platelets. | 1983 | J Pharmacol Methods | pmid:6843139 |
Rotmensch HH et al. | Plasma platelet products and exercise-induced myocardial ischemia. | 1983 | J. Lab. Clin. Med. | pmid:6854135 |
Hamelin SS and Chan AC | Modulation of platelet thromboxane and malonaldehyde by dietary vitamin E and linoleate. | 1983 | Lipids | pmid:6855486 |
Menys VC and Davies JA | Inhibitory effects of ZK 36374, a stable prostacyclin analogue, on adhesion of rabbit platelets to damaged aorta and serotonin release by adherent platelets. | 1983 | Clin. Sci. | pmid:6190604 |
Hartung HP and Toyka KV | Activation of macrophages by substance P: induction of oxidative burst and thromboxane release. | 1983 | Eur. J. Pharmacol. | pmid:6191998 |
Tanganelli I et al. | [Thromboxane, beta-thromboglobulin and the degree of blood sugar control in type 1 diabetes mellitus]. | 1983 | Boll. Soc. Ital. Biol. Sper. | pmid:6194801 |
Kangasaho M et al. | Formation of thromboxane B2 by platelets and concentrations of thromboxane B2 and 6-keto-prostaglandin F1 alpha in plasma after acute ethanol ingestion. | 1983 | Adv. Prostaglandin Thromboxane Leukot. Res. | pmid:6303086 |
Wientroub S et al. | Changes in tissue concentration of prostaglandins during endochondral bone differentiation. | 1983 | Biochem. Biophys. Res. Commun. | pmid:6582850 |
Deckmyn H et al. | Prostacyclin production by whole blood from children: impairment in the hemolytic uremic syndrome and excessive formation in chronic renal failure. | 1983 | Thromb. Res. | pmid:6344317 |
Ylikorkala O and Viinikka L | Prostaglandins and endometriosis. | 1983 | Acta Obstet Gynecol Scand Suppl | pmid:6344540 |
Ylikorkala O | Prostacyclin and thromboxane during human pregnancy. | 1983 | Acta Obstet Gynecol Scand Suppl | pmid:6344543 |
Qvist R and Larkins RG | Diminished production of thromboxane B2 and prostaglandin E by stimulated polymorphonuclear leukocytes from insulin-treated diabetic subjects. | 1983 | Diabetes | pmid:6345241 |
Newman JH et al. | Effects of 100% oxygen on lung vascular function in awake sheep. | 1983 | J Appl Physiol Respir Environ Exerc Physiol | pmid:6345493 |
Eldor A et al. | Effects of dipyrone on prostaglandin production by human platelets and cultured bovine aortic endothelial cells. | 1983 | Thromb. Haemost. | pmid:6346571 |
Menys VC and Davies JA | Selective inhibition of thromboxane synthetase with dazoxiben - basis of its inhibitory effect on platelet adhesion. | 1983 | Thromb. Haemost. | pmid:6346575 |
Reeves WC et al. | The release of thromboxane A2 and prostacyclin following experimental acute pulmonary embolism. | 1983 | Prostaglandins Leukot Med | pmid:6348800 |
Aznavoorian SA et al. | Prostacyclin inhibits 5-hydroxytryptamine release but stimulates thromboxane synthesis during cardiopulmonary bypass. | 1983 | Prostaglandins | pmid:6348886 |
Kiff PS et al. | Haemodynamic and metabolic effects of dazoxiben at rest and during atrial pacing. | 1983 | Br J Clin Pharmacol | pmid:6681708 |
Hutton I et al. | Effects of dazoxiben on transcardiac thromboxane levels and haemodynamics in coronary heart disease. | 1983 | Br J Clin Pharmacol | pmid:6681709 |
Zijlstra FJ et al. | Thrombotic thrombocytopenic purpura and plasma thromboxane B2 levels. | 1983 | Thromb. Res. | pmid:6684333 |
Lianos EA et al. | Glomerular prostaglandin and thromboxane synthesis in rat nephrotoxic serum nephritis. Effects on renal hemodynamics. | 1983 | J. Clin. Invest. | pmid:6685136 |
Sakamoto T | [Studies on platelet function in toxemia of pregnancy]. | 1983 | Nippon Sanka Fujinka Gakkai Zasshi | pmid:6223964 |
Winchester JF et al. | Early indicators of renal allograft rejection. | 1983 | Kidney Int. Suppl. | pmid:6224041 |
Westwick J et al. | Platelet activation during steady state sickle cell disease. | 1983 | J Med | pmid:6224876 |
Muccitelli RM et al. | Effect of inhibition of thromboxane production on the leukotriene D4-mediated bronchoconstriction in the guinea pig. | 1983 | Prostaglandins | pmid:6689082 |
Dale J et al. | The effect of a thromboxane synthetase inhibitor, dazoxiben, and acetylsalicylic acid on platelet function and prostaglandin metabolism. | 1983 | Thromb. Haemost. | pmid:6689091 |
Liu J | [Effect of Paeonia obovata 801 on metabolism of thromboxane B2 and arachidonic acid and on platelet aggregation in patients with coronary heart disease and cerebral thrombosis]. | 1983 | Zhonghua Yi Xue Za Zhi | pmid:6418338 |
Aehringhaus U et al. | Effect of inhibition of synthesis and receptor antagonism of SRS-A in cardiac anaphylaxis. | 1983 | Br. J. Pharmacol. | pmid:6689134 |
Kurata M | [Relation between mouse peritoneal macrophage functions and prostaglandins]. | 1983 | Rinsho Byori | pmid:6689184 |
Maguire ED and Wallis RB | In vivo redirection of prostaglandin endoperoxides into 6-keto PGF1 alpha formation by thromboxane synthetase inhibitors in the rat. | 1983 | Thromb. Res. | pmid:6689221 |
McDonald JW and Ali M | Recovery of cyclooxygenase activity after aspirin in populations of platelets separated on stractan density gradients. | 1983 | Prostaglandins Leukot Med | pmid:6419234 |
Zijlstra FJ and Vincent JE | Comparison of the determination of thromboxane A2 by bioassay on the rabbit mesenteric artery and in the form of TxB2 by radioimmunoassay. | 1983 | J Pharmacol Methods | pmid:6632924 |
Bryant RW and Hwang DH | Development of a radioimmunoassay for 15-HETE and its application to 15-HETE production by reticulocytes. | 1983 | Prostaglandins | pmid:6419285 |
Wilson L | Effects of estradiol and progesterone on uterine prostaglandin levels in the pregnant rat. | 1983 | Prostaglandins | pmid:6635211 |
Sanders TA and Hochland MC | A comparison of the influence on plasma lipids and platelet function of supplements of omega 3 and omega 6 polyunsaturated fatty acids. | 1983 | Br. J. Nutr. | pmid:6639916 |
Mehta JL | Prostaglandins: regulatory role in cardiovascular system and implications in ischemic heart disease. | 1983 | Int. J. Cardiol. | pmid:6642760 |
Zipser RD et al. | Urinary thromboxane B2 and prostaglandin E2 in the hepatorenal syndrome: evidence for increased vasoconstrictor and decreased vasodilator factors. | 1983 | Gastroenterology | pmid:6572162 |
Schenkelaars EJ and Bonta IL | Effect of leukotriene C4 on the release of secretory products by elicited populations of rat peritoneal macrophages. | 1983 | Eur. J. Pharmacol. | pmid:6572592 |
Rocklin RE et al. | Augmentation of prostaglandin and thromboxane production in vitro by monocytes exposed to histamine-induced suppressor factor (HSF). | 1983 | Cell. Immunol. | pmid:6573232 |
Ouwendijk RJ et al. | Raised plasma thromboxane B2 levels in alcoholic liver disease. | 1983 | Prostaglandins Leukot Med | pmid:6573682 |
Hornych A et al. | Thromboxane B2 in borderline and essential hypertensive patients. | 1983 | Prostaglandins Leukot Med | pmid:6573683 |
Flynn JT et al. | Effects of anesthesia and surgery on prostanoid concentrations in plasma and pulmonary lymph. | 1983 | Prostaglandins Leukot Med | pmid:6573688 |
Patel K and Bakhle YS | Thromboxane B2 (TxB2) metabolism in rat isolated lung and its inhibition by drugs. | 1983 | Prostaglandins Leukot Med | pmid:6573689 |
Davì G et al. | Plasmatic TXB2 and 6-keto-PGF1 alpha levels during charcoal hemoperfusion in chronic renal failure patients. | 1983 | Prostaglandins Leukot Med | pmid:6573692 |
Lieb J et al. | Elevated levels of prostaglandin E2 and thromboxane B2 in depression. | 1983 | Prostaglandins Leukot Med | pmid:6574523 |