Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Acute Kidney Injury D058186 34 associated lipids
Airway Remodeling D056151 3 associated lipids
Acute Coronary Syndrome D054058 11 associated lipids
Hypoalphalipoproteinemias D052456 5 associated lipids
Atherosclerosis D050197 85 associated lipids
Dyslipidemias D050171 7 associated lipids
Cholecystitis, Acute D041881 1 associated lipids
Pulmonary Disease, Chronic Obstructive D029424 16 associated lipids
Metabolic Syndrome D024821 44 associated lipids
Coronary Stenosis D023921 6 associated lipids
Hypoxia-Ischemia, Brain D020925 22 associated lipids
Stroke D020521 32 associated lipids
Latex Hypersensitivity D020315 1 associated lipids
Intracranial Hemorrhage, Hypertensive D020299 1 associated lipids
Ventricular Remodeling D020257 28 associated lipids
Venous Thrombosis D020246 11 associated lipids
Infarction, Middle Cerebral Artery D020244 35 associated lipids
Carotid Artery Injuries D020212 8 associated lipids
Sleep Apnea, Obstructive D020181 9 associated lipids
Basal Ganglia Hemorrhage D020145 1 associated lipids
Thrombophilia D019851 6 associated lipids
Endotoxemia D019446 27 associated lipids
Pancreatitis, Acute Necrotizing D019283 18 associated lipids
Atrial Premature Complexes D018880 1 associated lipids
Sepsis D018805 11 associated lipids
Systemic Inflammatory Response Syndrome D018746 4 associated lipids
Ventricular Dysfunction, Left D018487 33 associated lipids
Osteoblastoma D018215 1 associated lipids
Aortic Aneurysm, Abdominal D017544 5 associated lipids
Hypertrophy, Left Ventricular D017379 12 associated lipids
beta-Thalassemia D017086 5 associated lipids
Carotid Stenosis D016893 15 associated lipids
Death, Sudden, Cardiac D016757 12 associated lipids
Yang Deficiency D016711 3 associated lipids
Diabetes, Gestational D016640 8 associated lipids
Bronchial Hyperreactivity D016535 15 associated lipids
Peripheral Vascular Diseases D016491 8 associated lipids
Helicobacter Infections D016481 21 associated lipids
Bacteremia D016470 9 associated lipids
Leukemia, Myeloid, Acute D015470 19 associated lipids
Glomerulonephritis, Membranous D015433 6 associated lipids
Weight Loss D015431 56 associated lipids
Weight Gain D015430 101 associated lipids
Myocardial Reperfusion Injury D015428 20 associated lipids
Reperfusion Injury D015427 65 associated lipids
Zellweger Syndrome D015211 39 associated lipids
Wounds and Injuries D014947 20 associated lipids
Weil Disease D014895 2 associated lipids
Granulomatosis with Polyangiitis D014890 5 associated lipids
Vitamin E Deficiency D014811 29 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

Download all related citations
Per page 10 20 50 100 | Total 6367
Authors Title Published Journal PubMed Link
Düsing R et al. Dietary linoleic acid deprivation: effects on blood pressure and PGI2 synthesis. 1983 Am. J. Physiol. pmid:6337507
Saldeen P et al. Increased synthesis of thromboxane B2 and 6-keto-PGF1 alpha in hand veins from patients with deep venous thrombosis. 1983 Thromb. Res. pmid:6658723
McManus LM et al. Thromboxane B2 (TxB2) release following acetyl glyceryl ether phosphorylcholine (AGEPC) infusion in the rabbit. 1983 Immunopharmacology pmid:6832960
Martin JL et al. Effect of atrial pacing on intracoronary thromboxane production in coronary artery disease. 1983 J. Am. Coll. Cardiol. pmid:6833660
Ferraris VA and Swanson E Aspirin usage and perioperative blood loss in patients undergoing unexpected operations. 1983 Surg Gynecol Obstet pmid:6836459
Margotat A et al. A rapid and simple assay for the study of thromboxane B2 synthesis by intact human platelets. 1983 J Pharmacol Methods pmid:6843139
Rotmensch HH et al. Plasma platelet products and exercise-induced myocardial ischemia. 1983 J. Lab. Clin. Med. pmid:6854135
Hamelin SS and Chan AC Modulation of platelet thromboxane and malonaldehyde by dietary vitamin E and linoleate. 1983 Lipids pmid:6855486
Menys VC and Davies JA Inhibitory effects of ZK 36374, a stable prostacyclin analogue, on adhesion of rabbit platelets to damaged aorta and serotonin release by adherent platelets. 1983 Clin. Sci. pmid:6190604
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Deckmyn H et al. Prostacyclin production by whole blood from children: impairment in the hemolytic uremic syndrome and excessive formation in chronic renal failure. 1983 Thromb. Res. pmid:6344317
Ylikorkala O and Viinikka L Prostaglandins and endometriosis. 1983 Acta Obstet Gynecol Scand Suppl pmid:6344540
Ylikorkala O Prostacyclin and thromboxane during human pregnancy. 1983 Acta Obstet Gynecol Scand Suppl pmid:6344543
Qvist R and Larkins RG Diminished production of thromboxane B2 and prostaglandin E by stimulated polymorphonuclear leukocytes from insulin-treated diabetic subjects. 1983 Diabetes pmid:6345241
Newman JH et al. Effects of 100% oxygen on lung vascular function in awake sheep. 1983 J Appl Physiol Respir Environ Exerc Physiol pmid:6345493
Eldor A et al. Effects of dipyrone on prostaglandin production by human platelets and cultured bovine aortic endothelial cells. 1983 Thromb. Haemost. pmid:6346571
Menys VC and Davies JA Selective inhibition of thromboxane synthetase with dazoxiben - basis of its inhibitory effect on platelet adhesion. 1983 Thromb. Haemost. pmid:6346575
Reeves WC et al. The release of thromboxane A2 and prostacyclin following experimental acute pulmonary embolism. 1983 Prostaglandins Leukot Med pmid:6348800
Aznavoorian SA et al. Prostacyclin inhibits 5-hydroxytryptamine release but stimulates thromboxane synthesis during cardiopulmonary bypass. 1983 Prostaglandins pmid:6348886
Kiff PS et al. Haemodynamic and metabolic effects of dazoxiben at rest and during atrial pacing. 1983 Br J Clin Pharmacol pmid:6681708
Hutton I et al. Effects of dazoxiben on transcardiac thromboxane levels and haemodynamics in coronary heart disease. 1983 Br J Clin Pharmacol pmid:6681709
Zijlstra FJ et al. Thrombotic thrombocytopenic purpura and plasma thromboxane B2 levels. 1983 Thromb. Res. pmid:6684333
Lianos EA et al. Glomerular prostaglandin and thromboxane synthesis in rat nephrotoxic serum nephritis. Effects on renal hemodynamics. 1983 J. Clin. Invest. pmid:6685136
Sakamoto T [Studies on platelet function in toxemia of pregnancy]. 1983 Nippon Sanka Fujinka Gakkai Zasshi pmid:6223964
Winchester JF et al. Early indicators of renal allograft rejection. 1983 Kidney Int. Suppl. pmid:6224041
Westwick J et al. Platelet activation during steady state sickle cell disease. 1983 J Med pmid:6224876
Muccitelli RM et al. Effect of inhibition of thromboxane production on the leukotriene D4-mediated bronchoconstriction in the guinea pig. 1983 Prostaglandins pmid:6689082
Dale J et al. The effect of a thromboxane synthetase inhibitor, dazoxiben, and acetylsalicylic acid on platelet function and prostaglandin metabolism. 1983 Thromb. Haemost. pmid:6689091
Liu J [Effect of Paeonia obovata 801 on metabolism of thromboxane B2 and arachidonic acid and on platelet aggregation in patients with coronary heart disease and cerebral thrombosis]. 1983 Zhonghua Yi Xue Za Zhi pmid:6418338
Aehringhaus U et al. Effect of inhibition of synthesis and receptor antagonism of SRS-A in cardiac anaphylaxis. 1983 Br. J. Pharmacol. pmid:6689134
Kurata M [Relation between mouse peritoneal macrophage functions and prostaglandins]. 1983 Rinsho Byori pmid:6689184
Maguire ED and Wallis RB In vivo redirection of prostaglandin endoperoxides into 6-keto PGF1 alpha formation by thromboxane synthetase inhibitors in the rat. 1983 Thromb. Res. pmid:6689221
McDonald JW and Ali M Recovery of cyclooxygenase activity after aspirin in populations of platelets separated on stractan density gradients. 1983 Prostaglandins Leukot Med pmid:6419234
Zijlstra FJ and Vincent JE Comparison of the determination of thromboxane A2 by bioassay on the rabbit mesenteric artery and in the form of TxB2 by radioimmunoassay. 1983 J Pharmacol Methods pmid:6632924
Bryant RW and Hwang DH Development of a radioimmunoassay for 15-HETE and its application to 15-HETE production by reticulocytes. 1983 Prostaglandins pmid:6419285
Wilson L Effects of estradiol and progesterone on uterine prostaglandin levels in the pregnant rat. 1983 Prostaglandins pmid:6635211
Sanders TA and Hochland MC A comparison of the influence on plasma lipids and platelet function of supplements of omega 3 and omega 6 polyunsaturated fatty acids. 1983 Br. J. Nutr. pmid:6639916
Mehta JL Prostaglandins: regulatory role in cardiovascular system and implications in ischemic heart disease. 1983 Int. J. Cardiol. pmid:6642760
Zipser RD et al. Urinary thromboxane B2 and prostaglandin E2 in the hepatorenal syndrome: evidence for increased vasoconstrictor and decreased vasodilator factors. 1983 Gastroenterology pmid:6572162
Schenkelaars EJ and Bonta IL Effect of leukotriene C4 on the release of secretory products by elicited populations of rat peritoneal macrophages. 1983 Eur. J. Pharmacol. pmid:6572592
Rocklin RE et al. Augmentation of prostaglandin and thromboxane production in vitro by monocytes exposed to histamine-induced suppressor factor (HSF). 1983 Cell. Immunol. pmid:6573232
Ouwendijk RJ et al. Raised plasma thromboxane B2 levels in alcoholic liver disease. 1983 Prostaglandins Leukot Med pmid:6573682
Hornych A et al. Thromboxane B2 in borderline and essential hypertensive patients. 1983 Prostaglandins Leukot Med pmid:6573683
Flynn JT et al. Effects of anesthesia and surgery on prostanoid concentrations in plasma and pulmonary lymph. 1983 Prostaglandins Leukot Med pmid:6573688
Patel K and Bakhle YS Thromboxane B2 (TxB2) metabolism in rat isolated lung and its inhibition by drugs. 1983 Prostaglandins Leukot Med pmid:6573689
Davì G et al. Plasmatic TXB2 and 6-keto-PGF1 alpha levels during charcoal hemoperfusion in chronic renal failure patients. 1983 Prostaglandins Leukot Med pmid:6573692
Lieb J et al. Elevated levels of prostaglandin E2 and thromboxane B2 in depression. 1983 Prostaglandins Leukot Med pmid:6574523