Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

Cross Reference

Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Acute Kidney Injury D058186 34 associated lipids
Airway Remodeling D056151 3 associated lipids
Acute Coronary Syndrome D054058 11 associated lipids
Hypoalphalipoproteinemias D052456 5 associated lipids
Atherosclerosis D050197 85 associated lipids
Dyslipidemias D050171 7 associated lipids
Cholecystitis, Acute D041881 1 associated lipids
Pulmonary Disease, Chronic Obstructive D029424 16 associated lipids
Metabolic Syndrome D024821 44 associated lipids
Coronary Stenosis D023921 6 associated lipids
Hypoxia-Ischemia, Brain D020925 22 associated lipids
Stroke D020521 32 associated lipids
Latex Hypersensitivity D020315 1 associated lipids
Intracranial Hemorrhage, Hypertensive D020299 1 associated lipids
Ventricular Remodeling D020257 28 associated lipids
Venous Thrombosis D020246 11 associated lipids
Infarction, Middle Cerebral Artery D020244 35 associated lipids
Carotid Artery Injuries D020212 8 associated lipids
Sleep Apnea, Obstructive D020181 9 associated lipids
Basal Ganglia Hemorrhage D020145 1 associated lipids
Thrombophilia D019851 6 associated lipids
Endotoxemia D019446 27 associated lipids
Pancreatitis, Acute Necrotizing D019283 18 associated lipids
Atrial Premature Complexes D018880 1 associated lipids
Sepsis D018805 11 associated lipids
Systemic Inflammatory Response Syndrome D018746 4 associated lipids
Ventricular Dysfunction, Left D018487 33 associated lipids
Osteoblastoma D018215 1 associated lipids
Aortic Aneurysm, Abdominal D017544 5 associated lipids
Hypertrophy, Left Ventricular D017379 12 associated lipids
beta-Thalassemia D017086 5 associated lipids
Carotid Stenosis D016893 15 associated lipids
Death, Sudden, Cardiac D016757 12 associated lipids
Yang Deficiency D016711 3 associated lipids
Diabetes, Gestational D016640 8 associated lipids
Bronchial Hyperreactivity D016535 15 associated lipids
Peripheral Vascular Diseases D016491 8 associated lipids
Helicobacter Infections D016481 21 associated lipids
Bacteremia D016470 9 associated lipids
Leukemia, Myeloid, Acute D015470 19 associated lipids
Glomerulonephritis, Membranous D015433 6 associated lipids
Weight Loss D015431 56 associated lipids
Weight Gain D015430 101 associated lipids
Myocardial Reperfusion Injury D015428 20 associated lipids
Reperfusion Injury D015427 65 associated lipids
Zellweger Syndrome D015211 39 associated lipids
Wounds and Injuries D014947 20 associated lipids
Weil Disease D014895 2 associated lipids
Granulomatosis with Polyangiitis D014890 5 associated lipids
Vitamin E Deficiency D014811 29 associated lipids
Per page 10 20 50 100 | Total 293

PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

Download all related citations
Per page 10 20 50 100 | Total 6367
Authors Title Published Journal PubMed Link
Persico N et al. Transdermal hormone replacement therapy and Doppler findings in normal and overweight postmenopausal patients. 2004 Gynecol. Endocrinol. pmid:15726916
He J et al. Treatment of unstable angina pectoris with modified nuan gan jian--a report of 33 cases. 2004 J Tradit Chin Med pmid:15688691
Arruzazabala ML et al. Effects of d-003, a new substance purified from sugar cane wax, on platelet aggregation and plasma levels of arachidonic acid metabolites in healthy volunteers. 2004 Int J Clin Pharmacol Res pmid:15689052
Gross GJ and Moore J Effect of COX-1/COX-2 inhibition versus selective COX-2 inhibition on coronary vasodilator responses to arachidonic acid and acetylcholine. 2004 Pharmacology pmid:15161995
Suzuki N et al. Quantitative liquid chromatography-tandem mass spectrometric analysis of 11-dehydro TXB2 in urine. 2004 Prostaglandins Other Lipid Mediat. pmid:15165035
Kudolo GB et al. The ingestion of Ginkgo biloba extract (EGb 761) inhibits arachidonic acid-mediated platelet aggregation and thromboxane B2 production in healthy volunteers. 2004 J Herb Pharmacother pmid:15927922
Lam AN et al. Effect of red clover isoflavones on cox-2 activity in murine and human monocyte/macrophage cells. 2004 Nutr Cancer pmid:15456640
Zhao GR et al. [Clinical study on relationship between sluggishness of lung-defensive qi and levels of vasoactive intestinal polypeptide and thromboxane B2]. 2004 Zhong Xi Yi Jie He Xue Bao pmid:15383251
Fiorucci S et al. Co-administration of nitric oxide-aspirin (NCX-4016) and aspirin prevents platelet and monocyte activation and protects against gastric damage induced by aspirin in humans. 2004 J. Am. Coll. Cardiol. pmid:15358033
Ming HX et al. [Influence of single leaf Asarum himalaicum on renal function of rabbits]. 2004 Zhong Xi Yi Jie He Xue Bao pmid:15339444
Dey A et al. Altered kidney CYP2C and cyclooxygenase-2 levels are associated with obesity-related albuminuria. 2004 Obes. Res. pmid:15340111
Sheu JR et al. Expression of matrix metalloproteinase-9 in human platelets: regulation of platelet activation in in vitro and in vivo studies. 2004 Br. J. Pharmacol. pmid:15289295
Toth B et al. Insights into the role of interleukin-6 in the induction of hepatic injury after trauma-hemorrhagic shock. 2004 J. Appl. Physiol. pmid:15298985
Craft JA et al. Increased platelet-derived microparticles in the coronary circulation of percutaneous transluminal coronary angioplasty patients. 2004 Blood Coagul. Fibrinolysis pmid:15311156
Ferroni P et al. Platelet activation in type 2 diabetes mellitus. 2004 J. Thromb. Haemost. pmid:15304032
Di Nunno L et al. Novel synthesis of 3,4-diarylisoxazole analogues of valdecoxib: reversal cyclooxygenase-2 selectivity by sulfonamide group removal. 2004 J. Med. Chem. pmid:15369392
Mak IT et al. Cardiac pathologic effects of azidothymidine (AZT) in Mg-deficient mice. 2004 Cardiovasc. Toxicol. pmid:15371632
Valeri CR et al. In vitro effects of poly-N-acetyl glucosamine on the activation of platelets in platelet-rich plasma with and without red blood cells. 2004 J Trauma pmid:15280746
Singer P and Wirth M Can n-3 PUFA reduce cardiac arrhythmias? Results of a clinical trial. 2004 Prostaglandins Leukot. Essent. Fatty Acids pmid:15253884
Menzies-Gow NJ et al. Endotoxin-induced digital vasoconstriction in horses: associated changes in plasma concentrations of vasoconstrictor mediators. 2004 Equine Vet. J. pmid:15147137
Ghuysen A et al. Effect of BM-573 [N-terbutyl-N'-[2-(4'-methylphenylamino)-5-nitro-benzenesulfonyl]urea], a dual thromboxane synthase inhibitor and thromboxane receptor antagonist, in a porcine model of acute pulmonary embolism. 2004 J. Pharmacol. Exp. Ther. pmid:15121765
Caprani A et al. Experimental evidence of a potentially increased thrombo-embolic disease risk by domestic electromagnetic field exposure. 2004 Bioelectromagnetics pmid:15114641
Di Minno G and Violi F Aspirin resistance and diabetic angiopathy: back to the future. 2004 Thromb. Res. pmid:15115664
Torsney E et al. Thrombosis and neointima formation in vein grafts are inhibited by locally applied aspirin through endothelial protection. 2004 Circ. Res. pmid:15117816
Wang YY et al. Inhibition of platelet aggregation by polyaspartoyl L-arginine and its mechanism. 2004 Acta Pharmacol. Sin. pmid:15066215
Park HS et al. Dietary conjugated linoleic acid increases the mRNA ratio of Bax/Bcl-2 in the colonic mucosa of rats. 2004 J. Nutr. Biochem. pmid:15068816
Zhang C et al. Inhibition of inflammation contributes to organ protection of atenolol in sinoaortic-denervated rats. 2004 J. Cardiovasc. Pharmacol. pmid:15071353
Bruno A et al. Serial urinary 11-dehydrothromboxane B2, aspirin dose, and vascular events in blacks after recent cerebral infarction. 2004 Stroke pmid:14963281
Kwak SH et al. Effects of propofol on endotoxin-induced acute lung injury in rabbit. 2004 J. Korean Med. Sci. pmid:14966342
Scott G et al. Lumiracoxib: pharmacokinetic and pharmacodynamic profile when coadministered with fluconazole in healthy subjects. 2004 J Clin Pharmacol pmid:14747429
Arrebola MM et al. In vitro effects of clopidogrel on the platelet-subendothelium interaction, platelet thromboxane and endothelial prostacyclin production, and nitric oxide synthesis. 2004 J. Cardiovasc. Pharmacol. pmid:14668571
de La Puerta Vázquez R et al. Effects of different dietary oils on inflammatory mediator generation and fatty acid composition in rat neutrophils. 2004 Metab. Clin. Exp. pmid:14681843
Freitas CF et al. Role of endothelin-1 and thromboxane A2 in the pulmonary hypertension induced by heparin-protamine interaction in anesthetized dogs. 2004 J. Cardiovasc. Pharmacol. pmid:14668575
Cotter G et al. Lack of aspirin effect: aspirin resistance or resistance to taking aspirin? 2004 Am. Heart J. pmid:14760328
Wang MS et al. [The effects of lupus anticoagulant on pulmonary thromboembolism]. 2004 Zhonghua Jie He He Hu Xi Za Zhi pmid:15634384
Franz KB A functional biological marker is needed for diagnosing magnesium deficiency. 2004 J Am Coll Nutr pmid:15637224
Cardoni RL and Antúnez MI Circulating levels of cyclooxygenase metabolites in experimental Trypanosoma cruzi infections. 2004 Mediators Inflamm. pmid:15545053
Wu JX et al. Changes in somatostatin receptor expression of the pancreas and effectiveness of octreotide in rats with acute necrotizing pancreatitis. 2004 Chin J Dig Dis pmid:15612670
Berrougui H et al. Argan (Argania spinosa) oil lowers blood pressure and improves endothelial dysfunction in spontaneously hypertensive rats. 2004 Br. J. Nutr. pmid:15613254
Fan JG et al. [Dynamic changes of plasma levels of prostacycline and thromboxane A2 and their correlation with the severity of hepatic injury in rats with nonalcoholic fatty liver disease]. 2004 Zhonghua Gan Zang Bing Za Zhi pmid:15623379
Véricel E et al. Diabetic patients without vascular complications display enhanced basal platelet activation and decreased antioxidant status. 2004 Diabetes pmid:15047620
Yugar-Toledo JC et al. Uncontrolled hypertension, uncompensated type II diabetes, and smoking have different patterns of vascular dysfunction. 2004 Chest pmid:15006938
Vega-Ostertag M et al. Intracellular events in platelet activation induced by antiphospholipid antibodies in the presence of low doses of thrombin. 2004 Arthritis Rheum. pmid:15457460
Noverr MC and Huffnagle GB Regulation of Candida albicans morphogenesis by fatty acid metabolites. 2004 Infect. Immun. pmid:15501745
Tanigawa T et al. Anti-inflammatory effect of two isoforms of COX in H. pylori-induced gastritis in mice: possible involvement of PGE2. 2004 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:12958020
Rocca B et al. Modulation of the expression and activity of cyclooxygenases in normal and accelerated erythropoiesis. 2004 Exp. Hematol. pmid:15504548
Chou DS et al. Low concentration of oxidized low density lipoprotein suppresses platelet reactivity in vitro: an intracellular study. 2004 Lipids pmid:15506238
He W et al. Effects of the Chinese drugs for activating blood circulation on plasma TXB2 and 6-keto-PGF1alpha contents in rabbits with glucocorticoid-induced femoral head necrosis. 2004 J Tradit Chin Med pmid:15510809
Chiang N et al. Aspirin triggers antiinflammatory 15-epi-lipoxin A4 and inhibits thromboxane in a randomized human trial. 2004 Proc. Natl. Acad. Sci. U.S.A. pmid:15471991
Park WH et al. Inhibitory effect of GBH on platelet aggregation through inhibition of intracellular Ca2+ mobilization in activated human platelets. 2004 Life Sci. pmid:15474558