Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Cathcart MC et al. | Thromboxane synthase expression and correlation with VEGF and angiogenesis in non-small cell lung cancer. | 2014 | Biochim. Biophys. Acta | pmid:24480048 |
Chou YI et al. | Correlations of platelet-derived microparticles with thromboxane B2, platelet-activating factor, endothelin-1, and neutrophil to lymphocyte ratio in patients with coronary intermediate lesions. | 2014 | Biomarkers | pmid:25391885 |
Fuentes E et al. | A novel role of Eruca sativa Mill. (rocket) extract: antiplatelet (NF-κB inhibition) and antithrombotic activities. | 2014 | Nutrients | pmid:25514563 |
John F et al. | Elevated levels of leukotriene B4 and thromboxane B2 distinguish chest pain of cardiac and non cardiac origin. | 2013 May-Jun | Indian Heart J | pmid:23809385 |
Dudley A et al. | Cyclooxygenase expression and platelet function in healthy dogs receiving low-dose aspirin. | 2013 Jan-Feb | J. Vet. Intern. Med. | pmid:23278865 |
Maenthaisong R et al. | Clinical pharmacology of cyclooxygenase inhibition and pharmacodynamic interaction with aspirin by floctafenine in Thai healthy subjects. | 2013 Apr-Jun | Int J Immunopathol Pharmacol | pmid:23755755 |
Wu G et al. | Pravastatin inhibits plaque rupture and subsequent thrombus formation in atherosclerotic rabbits with hyperlipidemia. | 2013 | Chem. Pharm. Bull. | pmid:23207681 |
Shi JJ and Huang LF | [Effects of transcutaneous electrical acupoint stimulation of "Zusanli" (ST 36) on gastric mucosal injury in exercise stress-induced gastric ulcer rats]. | 2013 | Zhen Ci Yan Jiu | pmid:24006661 |
Steib CJ et al. | Functional relevance of the cannabinoid receptor 2 - heme oxygenase pathway: a novel target for the attenuation of portal hypertension. | 2013 | Life Sci. | pmid:24007798 |
DeFilippis AP et al. | Thromboxane A(2) generation, in the absence of platelet COX-1 activity, in patients with and without atherothrombotic myocardial infarction. | 2013 | Circ. J. | pmid:23985963 |
Siennicka A et al. | Haemostatic factors and intraluminal thrombus thickness in abdominal aortic aneurysm. Is secondary fibrinolysis relevant? | 2013 | J. Physiol. Pharmacol. | pmid:23959729 |
Kleinbongard P et al. | Aspirate from human stented native coronary arteries vs. saphenous vein grafts: more endothelin but less particulate debris. | 2013 | Am. J. Physiol. Heart Circ. Physiol. | pmid:23934849 |
Chen LB et al. | [Coagulation and prothrombotic state parameters: clinical analysis in early pregnancy]. | 2013 | Zhonghua Yi Xue Za Zhi | pmid:24284247 |
Santilli F et al. | Effects of high-amount-high-intensity exercise on in vivo platelet activation: modulation by lipid peroxidation and AGE/RAGE axis. | 2013 | Thromb. Haemost. | pmid:24030807 |
Kapłon-Cieślicka A et al. | Predictors of high platelet reactivity during aspirin treatment in patients with type 2 diabetes. | 2013 | Kardiol Pol | pmid:24065375 |
Jastrzębska M et al. | Factors influencing multiplate whole blood impedance platelet aggregometry measurements, during aspirin treatment in acute ischemic stroke: a pilot study. | 2013 | Blood Coagul. Fibrinolysis | pmid:24071649 |
Lv GY et al. | Combined antihypertensive effect of luteolin and buddleoside enriched extracts in spontaneously hypertensive rats. | 2013 | J Ethnopharmacol | pmid:24080032 |
Li H et al. | Select dietary phytochemicals function as inhibitors of COX-1 but not COX-2. | 2013 | PLoS ONE | pmid:24098505 |
Hau CS et al. | Suppressive effects of antimycotics on thymic stromal lymphopoietin production in human keratinocytes. | 2013 | J. Dermatol. Sci. | pmid:23688403 |
Drew RC et al. | Aspirin augments carotid-cardiac baroreflex sensitivity during muscle mechanoreflex and metaboreflex activation in humans. | 2013 | J. Appl. Physiol. | pmid:23970529 |
Leclerc P et al. | Characterization of a human and murine mPGES-1 inhibitor and comparison to mPGES-1 genetic deletion in mouse models of inflammation. | 2013 | Prostaglandins Other Lipid Mediat. | pmid:24045148 |
Yamamoto M et al. | Effects of continuous ingestion of hesperidin and glucosyl hesperidin on vascular gene expression in spontaneously hypertensive rats. | 2013 | J. Nutr. Sci. Vitaminol. | pmid:24418882 |
Sun Y et al. | Yeast exposure in the preparation of steamed rehmannia root improving its effects on alloxan-induced diabetic rats. | 2013 | J Ethnopharmacol | pmid:24041459 |
d'Emmanuele di Villa Bianca R et al. | Hydrogen sulphide pathway contributes to the enhanced human platelet aggregation in hyperhomocysteinemia. | 2013 | Proc. Natl. Acad. Sci. U.S.A. | pmid:24019484 |
Brose SA and Golovko MY | Eicosanoid post-mortem induction in kidney tissue is prevented by microwave irradiation. | 2013 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:24113545 |
Sayers BC et al. | Role of cyclooxygenase-2 in exacerbation of allergen-induced airway remodeling by multiwalled carbon nanotubes. | 2013 | Am. J. Respir. Cell Mol. Biol. | pmid:23642096 |
Reyes JJ et al. | Antiplatelet effect of new lipophilic hydroxytyrosol alkyl ether derivatives in human blood. | 2013 | Eur J Nutr | pmid:22584413 |
Vasudevan C et al. | The effect of parenteral lipid emulsions on pulmonary hemodynamics and eicosanoid metabolites in preterm infants: a pilot study. | 2013 | Nutr Clin Pract | pmid:24177284 |
Sadilkova L et al. | The effect of selected pre-analytical phase variables on plasma thromboxane Aâ‚‚ measurements in humans. | 2013 | Int J Lab Hematol | pmid:22908995 |
Brentnall C et al. | Influence of oxytetracycline on carprofen pharmacodynamics and pharmacokinetics in calves. | 2013 | J. Vet. Pharmacol. Ther. | pmid:22913421 |
Yi X et al. | Platelet response to aspirin in Chinese stroke patients is independent of genetic polymorphisms of COX-1 C50T and COX-2 G765C. | 2013 | J. Atheroscler. Thromb. | pmid:22972377 |
Barillà F et al. | Clopidogrel plus indobufen in acute coronary syndrome patients with hypersensitivity to aspirin undergoing percutaneous coronary intervention. | 2013 | Platelets | pmid:22646157 |
Broekema FI et al. | In vivo hemostatic efficacy of polyurethane foam compared to collagen and gelatin. | 2013 | Clin Oral Investig | pmid:22855267 |
McMahon GS et al. | Transient heparin-induced platelet activation linked to generation of platelet 12-lipoxygenase. Findings from a randomised controlled trial. | 2013 | Thromb. Haemost. | pmid:23494053 |
Dharmasaroja PA et al. | Aspirin nonresponders in patients with ischaemic stroke. | 2013 | Blood Coagul. Fibrinolysis | pmid:23429255 |
Shiraishi M et al. | Cholesterol enrichment of rabbit platelets enhances the Ca(2+) entry pathway induced by platelet-derived secondary feedback agonists. | 2013 | Life Sci. | pmid:23499558 |
Larsen SB et al. | Reduced antiplatelet effect of aspirin is associated with low-grade inflammation in patients with coronary artery disease. | 2013 | Thromb. Haemost. | pmid:23407706 |
Fox T et al. | Dysregulated heme oxygenase-ferritin system in pterygium pathogenesis. | 2013 | Cornea | pmid:23792437 |
Borst O et al. | Skepinone-L, a novel potent and highly selective inhibitor of p38 MAP kinase, effectively impairs platelet activation and thrombus formation. | 2013 | Cell. Physiol. Biochem. | pmid:23817201 |
Zhang J et al. | Effects of an aqueous extract of Crataegus pinnatifida Bge. var. major N.E.Br. fruit on experimental atherosclerosis in rats. | 2013 | J Ethnopharmacol | pmid:23685195 |
Wei XJ et al. | Effects of carboxymethylpachymaran on signal molecules in chicken immunocytes. | 2013 | Int. J. Biol. Macromol. | pmid:23664932 |
Kang JW et al. | Anti-platelet activity of erythro-(7S,8R)-7-acetoxy-3,4,3',5'-tetramethoxy-8-O-4'-neolignan from Myristica fragrans. | 2013 | Phytother Res | pmid:23296979 |
Snider AJ et al. | Inhibition of sphingosine kinase-2 in a murine model of lupus nephritis. | 2013 | PLoS ONE | pmid:23301082 |
Xue YT et al. | Effect of anger on endothelial-derived vasoactive factors in spontaneously hypertensive rats. | 2013 | Heart Lung Circ | pmid:23261325 |
Gao H et al. | Effects of Yerba Mate tea (Ilex paraguariensis) on vascular endothelial function and liver lipoprotein receptor gene expression in hyperlipidemic rats. | 2013 | Fitoterapia | pmid:23266732 |
Carroll RC et al. | A comparison of VerifyNowR with PlateletMappingR--detected aspirin resistance and correlation with urinary thromboxane. | 2013 | Anesth. Analg. | pmid:23302970 |
Towhid ST et al. | Stimulation of platelet death by vancomycin. | 2013 | Cell. Physiol. Biochem. | pmid:23363637 |
Ren R et al. | Modulation of platelet aggregation-related eicosanoid production by dietary F-fucoidan from brown alga Laminaria japonica in human subjects. | 2013 | Br. J. Nutr. | pmid:23374164 |
Gautier-Veyret E et al. | Intermittent hypoxia-activated cyclooxygenase pathway: role in atherosclerosis. | 2013 | Eur. Respir. J. | pmid:23060635 |
Xue J et al. | Inhibitory effects of Qushuanling Capsule () on thrombus formation and platelet aggregation in rats. | 2013 | Chin J Integr Med | pmid:23001461 |