Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Okamatsu S et al. | Effect of calcium channel blockers on arachidonate-induced sudden death in rabbits. | 1981 | Proc. Soc. Exp. Biol. Med. | pmid:6261265 |
Rao GH et al. | Modification of human platelet response to sodium arachidonate by membrane modulation. | 1981 | Prostaglandins Med | pmid:6261286 |
di Minno G et al. | Effects of any epoxymethano stable analogue of prostaglandin endoperoxides (U-46619) on human platelets. | 1981 | Thromb. Haemost. | pmid:6266066 |
Hyman AL et al. | Prostaglandins and the lung. | 1981 | Med. Clin. North Am. | pmid:7024664 |
Ylikorkala O et al. | Effect of cytostatics on prostaglandin F2 alpha prostacyclin, and thromboxane in patients with gynecologic malignancies. | 1981 | Obstet Gynecol | pmid:7024882 |
Siess W et al. | Stimulated platelet aggregation, thromboxane B2 formation and platelet sensitivity to prostacyclin - a critical evaluation. | 1981 | Thromb. Haemost. | pmid:7025338 |
Gonzalez-Crussi F et al. | Prostaglandins in histiocytosis-X. PG synthesis by histiocytosis-X cells. | 1981 | Am. J. Clin. Pathol. | pmid:6970520 |
Webb PJ et al. | Do prostacyclin and thromboxane play a role in endotoxic shock? | 1981 | Br J Surg | pmid:7025959 |
Araki H et al. | Mechanism of protection against arachidonate induced sudden death by glucocorticoid. | 1981 | Prostaglandins | pmid:7232764 |
Parks WM et al. | Comparative effect of ibuprofen on endothelial and platelet prostaglandin synthesis. | 1981 | J. Pharmacol. Exp. Ther. | pmid:7026767 |
Roy AC et al. | Effect of intravenous infusion of OKY-1581 (sodium-(E)-3-[4-(3-pyridylmethyl)phenyl] -2-methylacrylate) on circulatory thromboxane A2 and prostacyclin levels in anaesthetized baboon. | 1981 | Prostaglandins Med | pmid:7029585 |
Roselló J et al. | Quantitative profiling of the metabolic cascade of arachidonic acid by capillary gas chromatography mass spectrometry. | 1981 | Biomed. Mass Spectrom. | pmid:7236862 |
Stuart MJ | Effect of endotoxin on arachidonic acid release and thromboxane B2 production by human platelets. | 1981 | Am. J. Hematol. | pmid:7030066 |
Cook JA et al. | Sensitization of essential fatty acid-deficient rats to endotoxin by arachidonate pretreatment: role of thromboxane A2. | 1981 | Circ. Shock | pmid:7237685 |
Lorenz R et al. | Effects of very low versus standard dose acetyl salicylic acid, dipyridamole and sulfinpyrazone on platelet function and thromboxane formation in man. | 1981 | Eur. J. Pharmacol. | pmid:7238575 |
Polley MJ et al. | Human complement in the arachidonic acid transformation pathway in platelets. | 1981 | J. Exp. Med. | pmid:7241047 |
Greenberg S et al. | Pulmonary vascular smooth muscle function in porcine splanchnic arterial occlusion shock. | 1981 | Am. J. Physiol. | pmid:7246787 |
Townsend ER et al. | Preservation of platelets during extracorporeal circulation in sheep. A comparison between aspirin and sulfinpyrazone. | 1981 | Circ. Res. | pmid:7249281 |
Vermylen J et al. | Thromboxane synthetase inhibition as antithrombotic strategy. | 1981 | Lancet | pmid:6112447 |
Feuerstein N et al. | 3-deazaadenosine, a transmethylase inhibitor, suppresses the effect of lipopolysaccharide on release of prostacyclin and thromboxane. | 1981 | J. Pharm. Pharmacol. | pmid:6115021 |
Foegh ML et al. | Urine i-TXB2 in renal allograft rejection. | 1981 | Lancet | pmid:6115199 |
Utsunomiya T et al. | Maintenance of cardiodynamics with aspirin during abdominal aortic aneurysmectomy (AAA). | 1981 | Ann. Surg. | pmid:6117260 |
Mahoney DA et al. | Urinary thromboxane B2 on allograft rejection. | 1981 | Lancet | pmid:6118500 |
Allen JB et al. | Irradiation decreases vascular prostacyclin formation with no concomitant effect on platelet thromboxane production. | 1981 | Lancet | pmid:6118629 |
Stenson WF et al. | Metabolism of exogenous arachidonic acid by murine macrophage-like tumor cell lines. | 1981 | Prostaglandins | pmid:6803301 |
Kelly KL and Laychock SG | Prostaglandin synthesis and metabolism in isolated pancreatic islets of the rat. | 1981 | Prostaglandins | pmid:6803305 |
Livio M et al. | Differential effects of itanoxone--a new hypolipidemic and hypouricemic drug--on platelet and vascular prostaglandin generation in rats. | 1981 | Atherosclerosis | pmid:7259827 |
Sterin-Borda L et al. | Stimulating effect of thromboxane B2 on isolated rat atria. | 1981 | Experientia | pmid:7262286 |
Roberts LJ et al. | Metabolism of thromboxane B2 in man. Identification of twenty urinary metabolites. | 1981 | J. Biol. Chem. | pmid:7263660 |
Zijlstra FJ and Vincent JE | Contractile characteristics of the rat stomach strip and the rabbit aorta and mesenteric artery. | 1981 | J Pharmacol Methods | pmid:7265989 |
Gilani SH and Persaud TV | Embryopathic effects of thromboxane B2 in the chick. | 1981 | Prostaglandins Med | pmid:7267828 |
Anderson CB et al. | Thromboxane-B2 and renovascular resistance during hypothermic pulsatile perfusion. | 1981 | Transplant. Proc. | pmid:7268892 |
Allan G and Levi R | Thromboxane and prostacyclin release during cardiac immediate hypersensitivity reactions in vitro. | 1981 | J. Pharmacol. Exp. Ther. | pmid:6894166 |
Malemud CJ et al. | Prostaglandin biosynthesis by lapine articular chondrocytes in culture. | 1981 | Biochim. Biophys. Acta | pmid:6894251 |
Ohnishi H et al. | Effects of trapidil on thromboxane A2-induced aggregation of platelets, ischemic changes in heart and biosynthesis of thromboxane A2. | 1981 | Prostaglandins Med | pmid:6894333 |
Coker SJ et al. | Thromboxane and prostacyclin release from ischaemic myocardium in relation to arrhythmias. | 1981 | Nature | pmid:6894485 |
Bishai I and Coceani F | Transformations of prostaglandin H2 in the cat brain. | 1981 | Biochim. Biophys. Acta | pmid:6894549 |
Drake TS et al. | Peritoneal fluid thromboxane B2 and 6-keto-prostaglandin F1 alpha in endometriosis. | 1981 | Am. J. Obstet. Gynecol. | pmid:6894667 |
Halushka PV et al. | Protective effects of aspirin in endotoxic shock. | 1981 | J. Pharmacol. Exp. Ther. | pmid:6894770 |
Feuerstein N et al. | Leukotrienes C4 and D4 induce prostaglandin and thromboxane release from rat peritoneal macrophages. | 1981 | Br. J. Pharmacol. | pmid:6894882 |
Ylikorkala O and Viinikka L | Prostacyclin, thromboxane, and prostaglandin F2 alpha in maternal plasma during breast-feeding. | 1981 | Am. J. Obstet. Gynecol. | pmid:7011034 |
Seitz M et al. | The influence of synovial fluid from patients with rheumatoid arthritis on the proliferation of peripheral blood lymphocytes and the prostanoid release from monocytes. | 1981 | Agents Actions | pmid:7340450 |
Prancan A et al. | Platelet thromboxane production during endotoxin shock. | 1981 | Agents Actions | pmid:7340458 |
Hwang DH | Characteristics of the aggregation of platelets and the formation of prostaglandins (PGs) in rat. | 1981 | Prog. Lipid Res. | pmid:7342108 |
Morrison AR et al. | Thromboxane A2 is the major arachidonic acid metabolite of human cortical hydronephrotic tissue. | 1981 | Prostaglandins | pmid:6894498 |
She HS et al. | Metabolism of prostaglandin endoperoxide by microsomes from cat lung. | 1981 | Prostaglandins | pmid:6894797 |
Russell NH et al. | Platelet adenine nucleotides and arachidonic acid metabolism in the myeloproliferative disorders. | 1981 | Thromb. Res. | pmid:6794179 |
Honn KV and Meyer J | Thromboxanes and prostacyclin: positive and negative modulators of tumor growth. | 1981 | Biochem. Biophys. Res. Commun. | pmid:6274330 |
Shaw JO | Effects of extracellular Ca2+ and the intracellular Ca2+ antagonist 8-(n,n-diethylamino)octyl-3,4,5-trimethoxybenzoate on rabbit platelet conversion of arachidonic acid into thromboxane. | 1981 | Prostaglandins | pmid:6789402 |
Ingerman-Wojenski C et al. | Prostacyclin production in rabbit arteries in situ: inhibition by arachidonic acid-induced endothelial cell damage or by low-dose aspirin. | 1981 | Prostaglandins | pmid:6789404 |