Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

Cross Reference

Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Airway Obstruction D000402 13 associated lipids
Uremia D014511 33 associated lipids
Stomach Ulcer D013276 75 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Hypoxia D000860 23 associated lipids
Graft Occlusion, Vascular D006083 11 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Adenocarcinoma D000230 166 associated lipids
Ovarian Neoplasms D010051 10 associated lipids
Pain D010146 64 associated lipids
Contusions D003288 3 associated lipids
Autoimmune Diseases D001327 27 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Lung Diseases D008171 37 associated lipids
Lung Neoplasms D008175 171 associated lipids
Wounds and Injuries D014947 20 associated lipids
Pleurisy D010998 20 associated lipids
Burns D002056 34 associated lipids
Inflammation D007249 119 associated lipids
Reperfusion Injury D015427 65 associated lipids
Colitis D003092 69 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Diabetic Nephropathies D003928 39 associated lipids
Diabetic Retinopathy D003930 39 associated lipids
Cattle Diseases D002418 24 associated lipids
Fatty Liver D005234 48 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Mammary Neoplasms, Experimental D008325 67 associated lipids
Body Weight D001835 333 associated lipids
Edema D004487 152 associated lipids
Arthritis D001168 41 associated lipids
Arthritis, Experimental D001169 24 associated lipids
Hypotension D007022 41 associated lipids
Acute Kidney Injury D058186 34 associated lipids
Gastritis D005756 27 associated lipids
Heart Failure D006333 36 associated lipids
Pulmonary Edema D011654 23 associated lipids
Pulmonary Embolism D011655 5 associated lipids
Coronary Disease D003327 70 associated lipids
Liver Cirrhosis, Experimental D008106 36 associated lipids
Hypersensitivity D006967 22 associated lipids
Hypothyroidism D007037 32 associated lipids
Rhinitis D012220 10 associated lipids
Hypercapnia D006935 5 associated lipids
Arterial Occlusive Diseases D001157 12 associated lipids
Pain, Postoperative D010149 13 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

Download all related citations
Per page 10 20 50 100 | Total 6367
Authors Title Published Journal PubMed Link
Patrono C et al. Thromboxane-dependent platelet activation as a transducer of enhanced risk of coronary and cerebral thrombosis. 1991 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:1825389
Zhao Y et al. Thromboxane and leukotriene generation by mononuclearcytes from cardiac transplant patients. 1991 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:1825392
Vial JH et al. Rebound elevation in urinary thromboxane B2 and 6-keto-PGF1 alpha excretion after aspirin withdrawal. 1991 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:1825534
Ritter JM et al. On the mechanism of the prolonged action in man of GR32191, a thromboxane receptor antagonist. 1991 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:1825568
Hayashi Y et al. Radioimmunoassay of 11-dehydro-thromboxane B2 using monoclonal antibody. 1989 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:2526561
Knospe J et al. Derivatization of prostaglandins to corresponding anilides and analysis by HPLC. 1989 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:2526562
Samhoun MN et al. Differential effect of vasoactive intestinal peptide on contractions induced by leukotriene D4, histamine, and acetylcholine in guinea pig lung parenchyma in vitro. 1987 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:2960144
Granström E and Kumlin M Assay of thromboxane production in biological systems: reliability of TXB2 versus 11-dehydro-TXB2 as targets for measurement. 1987 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:2960161
Lecompte T et al. Radioimmunoassay for 11-dehydro-thromboxane B2 using an iodinated ligand: preliminary applications to human fluids. 1987 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:2960162
Catella F et al. Analysis of multiple thromboxane metabolites in plasma and urine. 1987 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:2960166
Alessandrini P et al. Eicosanoid biosynthesis in human diabetes mellitus. 1987 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:2960175
Nihei C et al. Clinical study on effect of thromboxane A2 synthetase inhibitor (OKY-046) to clarify the regulation of cerebral blood flow in cerebral thrombosis. 1987 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:2960210
Miyazaki H et al. Microdetermination of prostaglandins and thromboxane B2 by gas chromatography/high-resolution selected-ion monitoring. 1985 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:2936139
Kobayashi N et al. Effect of changes in prostaglandin synthesis by platelets and vessel wall on the formation of arterial thrombosis in rabbits. 1985 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:2936159
Nishikawa K et al. (E)-7-Phenyl-7-(3-pyridyl)-6-heptenoic acid (CV-4151): a potent, specific thromboxane A2 synthetase inhibitor. 1985 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:2936160
Takagi S and Den K Prostacyclin and thromboxane A2 in preeclamptic umbilical circulation. 1985 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:2936183
Granström E et al. Monitoring thromboxane production in vivo: metabolic and analytical aspects. 1985 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:2936194
FitzGerald GA et al. Analysis of urinary metabolites of thromboxane and prostacyclin by negative-ion chemical-ionization gas chromatography/mass spectrometry. 1985 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:2936207
Kuzuya T et al. Determination of plasma thromboxane B2 by radioimmunoassay: methodological problems and accuracy. 1985 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:2936210
Patrignani P et al. Characterization of the cyclooxygenase activity of human blood prostaglandin endoperoxide synthases. 1995 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:7732817