Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Darien BJ et al. | Low molecular weight heparin prevents the pulmonary hemodynamic and pathomorphologic effects of endotoxin in a porcine acute lung injury model. | 1998 | Shock | pmid:9565256 |
Muscará MN et al. | Effect of a nitric oxide-releasing naproxen derivative on hypertension and gastric damage induced by chronic nitric oxide inhibition in the rat. | 1998 | Life Sci. | pmid:9566780 |
Davì G et al. | Increased thromboxane metabolites excretion in liver cirrhosis. | 1998 | Thromb. Haemost. | pmid:9569186 |
Kosugi T et al. | Glomerular thromboxane contributes to pressor response in deoxycorticosterone acetate-salt hypertension. | 1998 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:9578151 |
Failli P et al. | Effect of some cyclooxygenase inhibitors on the increase in guanosine 3':5'-cyclic monophosphate induced by NO-donors in human whole platelets. | 1998 | Br. J. Pharmacol. | pmid:9579743 |
Fuse S et al. | Plasma thromboxane B2 concentration in patients with ventricular septal defect and pulmonary hypertension. | 1998 | Jpn. Circ. J. | pmid:9583446 |
Stamler A et al. | Low-dose dopexamine's effect on lung and gut function after CPB in a sheep model. | 1998 | J. Surg. Res. | pmid:9587356 |
Inoue H et al. | Changes in endothelin-1, 6-keto-PG-F1 alpha, and TX-B2 in random pattern flaps. | 1998 | J. Cardiovasc. Pharmacol. | pmid:9595517 |
Kalgutkar AS et al. | Aspirin-like molecules that covalently inactivate cyclooxygenase-2. | 1998 | Science | pmid:9596581 |
Heller DA et al. | Mortality and biomarkers of aging in heterogeneous stock (HS) mice. | 1998 | J. Gerontol. A Biol. Sci. Med. Sci. | pmid:9597046 |
Komarevtseva IA et al. | [Change in prostanoid metabolism in cystic kidney lesion]. | 1997 Sep-Dec | Ukr. Biokhim. Zh. | pmid:9606841 |
Cignarella A et al. | Platelet activation supports the development of venous thrombosis in hyperlipidemic rats. | 1998 | Blood Coagul. Fibrinolysis | pmid:9607118 |
van der Weiden RM et al. | Which prostanoid metabolites should be determined for the study of reproductive processes? | 1998 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:9610843 |
Beitz A | Influence of diet-modified lipoprotein fractions from rabbits on eicosanoid production and on proliferation of rabbit skin fibroblasts. | 1998 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:9610847 |
Agnoli GC et al. | Effects of experimental salt depletion on urinary prostanoid excretions in normal women. | 1998 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:9610848 |
Tsai WJ et al. | Characterization of the antiplatelet effects of (2S)-5-methoxy-6-methylflavan-7-ol from Draconis Resina. | 1998 | Eur. J. Pharmacol. | pmid:9617759 |
DeVries A et al. | Ketoconazole in the prevention of acute respiratory distress syndrome. | 1998 May-Jun | Pharmacotherapy | pmid:9620108 |
Bassiouny HS et al. | Low flow enhances platelet activation after acute experimental arterial injury. | 1998 | J. Vasc. Surg. | pmid:9620144 |
Gust R et al. | Synergistic hemodynamic effects of low-dose endotoxin and acute lung injury. | 1998 | Am. J. Respir. Crit. Care Med. | pmid:9620928 |
Ozyazgan I et al. | Eicosanoids and inflammatory cells in frostbitten tissue: prostacyclin, thromboxane, polymorphonuclear leukocytes, and mast cells. | 1998 | Plast. Reconstr. Surg. | pmid:9623831 |
Franconi F et al. | Further insights into the anti-aggregating activity of NMDA in human platelets. | 1998 | Br. J. Pharmacol. | pmid:9630340 |
Cadroy Y et al. | Arachidonic acid enhances the tissue factor expression of mononuclear cells by the cyclo-oxygenase-1 pathway: beneficial effect of n-3 fatty acids. | 1998 | J. Immunol. | pmid:9637532 |
Lees P et al. | Pharmacodynamics and pharmacokinetics of tolfenamic acid in ruminating calves: evaluation in models of acute inflammation. | 1998 | Vet. J. | pmid:9638074 |
Tu Y et al. | Effect of intra-arachnoid space perfusion on thromboxane A and prostacycline in experimental spinal cord injury. | 1997 | J. Tongji Med. Univ. | pmid:9639784 |
Bereczki C et al. | Increased platelet thromboxane release in focal segmental glomerulosclerosis. | 1998 | Nephrol. Dial. Transplant. | pmid:9641208 |
Li S and Tian H | [Oral low-dose magnesium gluconate preventing pregnancy induced hypertension]. | 1997 | Zhonghua Fu Chan Ke Za Zhi | pmid:9642379 |
RogovyÄ IuE | [Beta 2-microglobulin as a criterion of dysfunction in the regulation of proximal tubular activity in mercuric chloride-induced nephropathy]. | 1998 May-Jun | Urol Nefrol (Mosk) | pmid:9644989 |
Whiteford M et al. | Effect of liposome-encapsulated hemoglobin on the development of endotoxin-induced shock in the rat. | 1998 | Shock | pmid:9645495 |
Mainwaring RD et al. | Complement activation and cytokine generation after modified Fontan procedure. | 1998 | Ann. Thorac. Surg. | pmid:9647087 |
Assaley J et al. | Effects of magnesium sulfate infusion upon clotting parameters in patients with pre-eclampsia. | 1998 | J Perinat Med | pmid:9650132 |
Nagao T et al. | Effect of lipo-prostaglandin E1 on crescentic-type anti-glomerular basement membrane nephritis in rats. | 1998 | Eur. J. Pharmacol. | pmid:9650829 |
Harada Y et al. | Differing profiles of prostaglandin formation inhibition between selective prostaglandin H synthase-2 inhibitors and conventional NSAIDs in inflammatory and non-inflammatory sites of the rat. | 1998 | Prostaglandins Other Lipid Mediat. | pmid:9653772 |
Bordia A et al. | Effect of garlic (Allium sativum) on blood lipids, blood sugar, fibrinogen and fibrinolytic activity in patients with coronary artery disease. | 1998 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:9654398 |
Schuligoi R et al. | Effects of the cyclooxygenase-2 inhibitor NS-398 on thromboxane and leukotriene synthesis in rat peritoneal cells. | 1998 | Inflamm. Res. | pmid:9657255 |
Aoki T et al. | Difference of (Ca2+)i movements in platelets stimulated by thrombin and TRAP: the involvement of alpha(IIb)beta3-mediated TXA2 synthesis. | 1998 | Thromb. Haemost. | pmid:9657446 |
Bode-Böger SM et al. | Chronic dietary supplementation with L-arginine inhibits platelet aggregation and thromboxane A2 synthesis in hypercholesterolaemic rabbits in vivo. | 1998 | Cardiovasc. Res. | pmid:9659460 |
Adler S and Bollu R | Glomerular endothelial cell injury mediated by shiga-like toxin-1. | 1998 | Kidney Blood Press. Res. | pmid:9661132 |
Geertsen PF et al. | Renal haemodynamics, sodium and water reabsorption during continuous intravenous infusion of recombinant interleukin-2. | 1998 | Clin. Sci. | pmid:9662488 |
Kunitoh H et al. | A double-blind, placebo-controlled trial of the thromboxane synthetase blocker OKY-046 on bronchial hypersensitivity in bronchial asthma patients. | 1998 | J Asthma | pmid:9669829 |
Sheu JR et al. | Inhibitory mechanisms of naloxone on human platelets. | 1998 Jul-Aug | Clin. Exp. Pharmacol. Physiol. | pmid:9673433 |
Miyamoto A et al. | The role of thromboxane A2 in regulating porcine basilar arterial tone. | 1998 | J. Vet. Pharmacol. Ther. | pmid:9673964 |
Cheng Z et al. | Measurement of cyclooxygenase inhibition in vivo: a study of two non-steroidal anti-inflammatory drugs in sheep. | 1998 | Inflammation | pmid:9675607 |
Onizuka M et al. | Suppression of prostanoid formation and regulation of peripheral circulation after surgery using thrombin inhibitor (MD805). | 1998 | Surg. Today | pmid:9681611 |
De La Cruz JP et al. | Effect of camonagrel, a selective thromboxane synthase inhibitor, on retinal vascularization in experimental diabetes. | 1998 | Eur. J. Pharmacol. | pmid:9683018 |
Tewes KS et al. | Measurement of thromboxane B2 in platelet-rich human plasma by gas chromatography-mass spectrometry and gas chromatography-tandem mass spectrometry following extractive pentafluorobenzyl esterification. | 1998 | Anal. Biochem. | pmid:9683522 |
Stephenson AH et al. | 5,6-Epoxyeicosatrienoic acid reduces increases in pulmonary vascular resistance in the dog. | 1998 | Am. J. Physiol. | pmid:9688901 |
Bell JG et al. | Growth, mortality, tissue histopathology and fatty acid compositions, eicosanoid production and response to stress, in juvenile turbot fed diets rich in gamma-linolenic acid in combination with eicosapentaenoic acid or docosahexaenoic acid. | 1998 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:9690713 |
Napoli E and Franco N | [Thromboxane A2 production in the pathogenesis of diabetic complications]. | 1998 | Minerva Endocrinol. | pmid:9691631 |
Lebel B et al. | Inhibition of mediator release from dispersed nasal polyp cells by cyclosporin A. | 1998 | Int. Arch. Allergy Immunol. | pmid:9693278 |
Ali M et al. | Urothelial synthesis of prostanoids in the ovine ureter. | 1998 | Urol. Res. | pmid:9694598 |