Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Airway Obstruction D000402 13 associated lipids
Uremia D014511 33 associated lipids
Stomach Ulcer D013276 75 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Hypoxia D000860 23 associated lipids
Graft Occlusion, Vascular D006083 11 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Adenocarcinoma D000230 166 associated lipids
Ovarian Neoplasms D010051 10 associated lipids
Pain D010146 64 associated lipids
Contusions D003288 3 associated lipids
Autoimmune Diseases D001327 27 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Lung Diseases D008171 37 associated lipids
Lung Neoplasms D008175 171 associated lipids
Wounds and Injuries D014947 20 associated lipids
Pleurisy D010998 20 associated lipids
Burns D002056 34 associated lipids
Inflammation D007249 119 associated lipids
Reperfusion Injury D015427 65 associated lipids
Colitis D003092 69 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Diabetic Nephropathies D003928 39 associated lipids
Diabetic Retinopathy D003930 39 associated lipids
Cattle Diseases D002418 24 associated lipids
Fatty Liver D005234 48 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Mammary Neoplasms, Experimental D008325 67 associated lipids
Body Weight D001835 333 associated lipids
Edema D004487 152 associated lipids
Arthritis D001168 41 associated lipids
Arthritis, Experimental D001169 24 associated lipids
Hypotension D007022 41 associated lipids
Acute Kidney Injury D058186 34 associated lipids
Gastritis D005756 27 associated lipids
Heart Failure D006333 36 associated lipids
Pulmonary Edema D011654 23 associated lipids
Pulmonary Embolism D011655 5 associated lipids
Coronary Disease D003327 70 associated lipids
Liver Cirrhosis, Experimental D008106 36 associated lipids
Hypersensitivity D006967 22 associated lipids
Hypothyroidism D007037 32 associated lipids
Rhinitis D012220 10 associated lipids
Hypercapnia D006935 5 associated lipids
Arterial Occlusive Diseases D001157 12 associated lipids
Pain, Postoperative D010149 13 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

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Per page 10 20 50 100 | Total 6367
Authors Title Published Journal PubMed Link
Greer IA et al. Inhibition of thromboxane and prostacyclin production in whole blood by adrenoceptor antagonists. 1985 Prostaglandins Leukot Med pmid:2865745
Mikhailidis DP et al. The effect of non-specific beta-blockade on metabolic and haemostatic variables during hypoglycaemia. 1985 Diabetes Res. pmid:2866057
Mehta J et al. Increase in human platelet alpha 2-adrenergic receptor affinity for agonist in unstable angina. 1985 J. Lab. Clin. Med. pmid:2866219
Greer IA et al. A comparative study of the effects of adrenoceptor antagonists on platelet aggregation and thromboxane generation. 1985 Thromb. Haemost. pmid:2867620
Habenicht AJ et al. Human platelet-derived growth factor stimulates prostaglandin synthesis by activation and by rapid de novo synthesis of cyclooxygenase. 1985 J. Clin. Invest. pmid:3921570
Gragnoli G et al. Effects of somatostatin on the behaviour of thromboxane B2 and beta-thromboglobulin in type I diabetes. 1985 Acta Endocrinol. pmid:2408435
Yardumian DA et al. Platelet hyperaggregability occurring during prolonged continuous intravenous infusions of prostacyclin analogue ZK 36374. 1985 Br. J. Haematol. pmid:2408653
Patrassi GM et al. Contact phase of coagulation in diabetes mellitus after aspirin administration. 1985 Folia Haematol. Int. Mag. Klin. Morphol. Blutforsch. pmid:2410343
Schlondorff D and Satriano JA Interactions of vasopressin, cAMP, and prostaglandins in toad urinary bladder. 1985 Am. J. Physiol. pmid:2579584
Lord A et al. Leukotriene F4 and the release of arachidonic acid metabolites from perfused guinea pig lungs in vitro. 1985 Prostaglandins pmid:3923570
Shorr RI et al. In vitro effects of acetaminophen and its analogues on human platelet aggregation and thromboxane B2 synthesis. 1985 Thromb. Res. pmid:3923647
Francos GC et al. Dialysis-induced hypoxemia: membrane dependent and membrane independent causes. 1985 Am. J. Kidney Dis. pmid:3919574
Ylitalo P et al. Inhibition of prostaglandin synthesis by indomethacin interacts with the antihypertensive effect of atenolol. 1985 Clin. Pharmacol. Ther. pmid:3899459
Packham MA et al. Duration of the effect of aspirin on the synthesis of thromboxane by density subpopulations of rabbit platelets stimulated with thrombin. 1985 Blood pmid:3926022
Cattaneo M et al. Human platelet aggregation and release reaction induced by platelet activating factor (PAF-acether)--effects of acetylsalicylic acid and external ionized calcium. 1985 Thromb. Haemost. pmid:3927505
Mobley A and Tai HH Synergistic stimulation of thromboxane biosynthesis by calcium ionophore and phorbol ester or thrombin in human platelets. 1985 Biochem. Biophys. Res. Commun. pmid:3927908
Jakubowski JA et al. Cumulative antiplatelet effect of low-dose enteric coated aspirin. 1985 Br. J. Haematol. pmid:3927970
Mehta J et al. Influence of selective thromboxane synthetase blocker CGS-13080 on thromboxane and prostacyclin biosynthesis in whole blood: evidence for synthesis of prostacyclin by leukocytes from platelet-derived endoperoxides. 1985 J. Lab. Clin. Med. pmid:3928780
Brown CG and Poyser NL Further studies on prostaglandin and thromboxane production by the rat uterus during the oestrous cycle. 1985 J. Reprod. Fertil. pmid:3857345
Callahan KS et al. Enhancement of the antiaggregatory activity of prostacyclin by propranolol in human platelets. 1985 Circulation pmid:2986877
Sawada M et al. Enzyme-immunoassay of thromboxane B2 at the picogram level. 1985 Prostaglandins pmid:3929333
De Caterina R et al. Low-dose aspirin in patients recovering from myocardial infarction. Evidence for a selective inhibition of thromboxane-related platelet function. 1985 Eur. Heart J. pmid:3930246
Beatty CH et al. Metabolism of arachidonic acid by macaque platelets. Implications for studies on atherosclerosis. 1985 Atherosclerosis pmid:3924062
Apprill P et al. Cyclic blood flow variations induced by platelet-activating factor in stenosed canine coronary arteries despite inhibition of thromboxane synthetase, serotonin receptors, and alpha-adrenergic receptors. 1985 Circulation pmid:2988822
Fukuda Y [Plasma prostaglandin and thromboxane levels in asthmatic children]. 1985 Arerugi pmid:2992423
Gorczynska E et al. [Effect of various stimulators on cyclooxygenase activity, platelet aggregation and TxB2 synthesis after using a platelet inhibitor (Aspro Clear) in vivo and in vitro]. 1985 Wiad. Lek. pmid:3933184
Berman B et al. Interferon enhancement of HLA-DR antigen expression on epidermal Langerhans cells. 1985 J. Invest. Dermatol. pmid:2578172
Honda M et al. Effects of purified hog pancreatic kallikrein on the kinin-prostaglandin system and renin-angiotensin-aldosterone system. 1985 Nephron pmid:2993934
Shayevitz JR et al. Inhalation anesthetics augment oxidant-induced pulmonary vasoconstriction: evidence for a membrane effect. 1985 Anesthesiology pmid:3933385
Mehta P et al. Plasma concentrations of thromboxane and prostacyclin metabolites in patients with bone tumors. 1985 Am J Pediatr Hematol Oncol pmid:2994511
VanRollins M et al. Metabolism of 7,10,13,16-docosatetraenoic acid to dihomo-thromboxane, 14-hydroxy-7,10,12-nonadecatrienoic acid and hydroxy fatty acids by human platelets. 1985 Biochim. Biophys. Acta pmid:3918572
Baud L et al. Lipoxygenase products mediate the attachment of rat macrophages to glomeruli in vitro. 1985 Kidney Int. pmid:3927056
Benigni A et al. Inhibition of human platelet aggregation by parathyroid hormone. Is cyclic AMP implicated? 1985 Am. J. Nephrol. pmid:2996352
Leslie JB and Watkins WD Eicosanoids in the central nervous system. 1985 J. Neurosurg. pmid:2997413
Wilson TW and Tan LK Low plasma renin activity in diabetes. Relation to urine prostaglandin excretion. 1985 Diabetes pmid:3881302
Longenecker GL et al. Kinetics of ibuprofen effect on platelet and endothelial prostanoid release. 1985 Clin. Pharmacol. Ther. pmid:3882308
Mitchell JA et al. Effects of high frequency oscillatory ventilation compared to conventional ventilation upon pulmonary vascular prostanoid production in neonatal piglets. 1985 Prostaglandins Leukot Med pmid:3883366
Wenger H et al. Pulmonary dysfunction secondary to soft-tissue endotoxin. 1985 Arch Surg pmid:3883949
Schambelan M et al. Increased prostaglandin production by glomeruli isolated from rats with streptozotocin-induced diabetes mellitus. 1985 J. Clin. Invest. pmid:3156147
Schafer AI and Adelman B Plasmin inhibition of platelet function and of arachidonic acid metabolism. 1985 J. Clin. Invest. pmid:3156149
Sirois P et al. Role of cyclooxygenase products in the lung action of leukotrienes A4, B4, C4, D4 and E4. 1985 Pharmacology pmid:2997811
de Lorgeril M et al. Acute influence of cigarette smoke in platelets, catecholamines and neurophysins in the normal conditions of daily life. 1985 Eur. Heart J. pmid:2937635
Paajanen H and Kormano M Prostacyclin (PGI2) and thromboxane (TXA2) levels during intravenous contrast medium administration in CT. 1985 Eur J Radiol pmid:3896802
Yui Y et al. A new stable prostacyclin analogue OP41483 (15-cyclopentyl-omega-pentanor-5(E)-carbacyclin). 1985 Jpn. Circ. J. pmid:3897597
Túri S et al. [Changes in serum prostaglandin metabolites in Schönlein-Henoch purpura]. 1985 Orv Hetil pmid:3897944
Farias LR et al. Effect of prostaglandin blockers on ascites fluid in pancreatitis. 1985 Surgery pmid:3898455
Kubo K and Kobayashi T Effects of OKY-046, a selective thromboxane synthetase inhibitor, on endotoxin-induced lung injury in unanesthetized sheep. 1985 Am. Rev. Respir. Dis. pmid:3898941
Barst RJ and Stalcup SA Endothelial function in clinical pulmonary hypertension. 1985 Chest pmid:3899537
Pediconi M et al. Effects of acute and chronic ethanol administration on thromboxane and prostacyclin levels and release in rat brain cortex. 1985 Prostaglandins pmid:3901122
Neri Serneri GG et al. Abnormal cardiocoronary thromboxane A2 production in patients with unstable angina. 1985 Am. Heart J. pmid:3984828
Vesterqvist O et al. In vivo production of thromboxane in acute human myocardial infarction: a preliminary study. 1985 Thromb. Res. pmid:3992528
O'Byrne PM et al. Leukotriene B4 induces airway hyperresponsiveness in dogs. 1985 J. Appl. Physiol. pmid:3001017
Mayfield RK et al. Platelet function during continuous insulin infusion treatment in insulin-dependent diabetic patients. 1985 Diabetes pmid:3930325
Tanaka M and Shibata Y The different response of guinea pig peritoneal macrophages to various stimulators. 1985 Gen. Pharmacol. pmid:3930344
Preud'homme Y et al. Metabolism of arachidonic acid in rabbit iris and retina. 1985 Invest. Ophthalmol. Vis. Sci. pmid:3930417
Zahavi J and Zahavi M Enhanced platelet release reaction, shortened platelet survival time and increased platelet aggregation and plasma thromboxane B2 in chronic obstructive arterial disease. 1985 Thromb. Haemost. pmid:3158092
Martin JL et al. Effect of high dose aspirin on coronary hemodynamics during pacing-induced myocardial ischemia. 1985 J. Am. Coll. Cardiol. pmid:3968305
Roy L et al. Lack of efficacy of nafazatrom, a novel anti-thrombotic compound, in patients with coronary artery disease. 1985 Am. Heart J. pmid:3158183
De Caterina R et al. Inhibition of platelet aggregation and thromboxane B2 production during aspirin treatment: dependence on the dose of the aggregating agent. 1985 Thromb. Res. pmid:3975876
Pedrinelli R et al. The influence of selective and nonselective prostaglandin inhibition on renin. 1985 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:3159197
Cook JA et al. Exchange transfusions in rats with a perfluorated blood substitute: effect on thromboxane B2 levels during endotoxemia. 1985 Circ. Shock pmid:3978769
Reines HD et al. Dazoxiben in human sepsis and adult respiratory distress syndrome. 1985 Clin. Pharmacol. Ther. pmid:3979000
Greco NJ et al. Action of platelet-activating factor on type 1 diabetic human platelets. 1985 J. Lab. Clin. Med. pmid:3981054
Patterson GA et al. Effects of imidazole and indomethacin on fluid balance in isolated sheep lungs. 1985 J. Appl. Physiol. pmid:3884582
Kelley VE et al. A fish oil diet rich in eicosapentaenoic acid reduces cyclooxygenase metabolites, and suppresses lupus in MRL-lpr mice. 1985 J. Immunol. pmid:3918111
Schrör K et al. [Inhibition of platelet aggregation and thromboxane formation by the calcium antagonist nisoldipine following a single oral dose of 10 mg. A double-blind study in healthy probands]. 1985 Klin. Wochenschr. pmid:3838352
Bult H et al. Modification of endotoxin-induced haemodynamic and haematological changes in the rabbit by methylprednisolone, F(ab')2 fragments and rosmarinic acid. 1985 Br. J. Pharmacol. pmid:3838489
Prosdocimi M et al. Coronary and systemic 6-ketoprostaglandin F1 alpha and thromboxane B2 during myocardial ischemia in dog. 1985 Am. J. Physiol. pmid:3838623
Krieger BP et al. Mechanisms of interaction between oxygen and granulocytes in hyperoxic lung injury. 1985 J. Appl. Physiol. pmid:3838744
Valentovic MA and Lubawy WC Elevated glucose in vivo and in vitro adversely alters prostaglandin generation in rat aortas and platelets. 1985 Prostaglandins Leukot Med pmid:3903777
Bergqvist D et al. The effect of inhibition of thromboxane synthesis in experimental thrombosis and hemostasis. 1985 Thromb. Res. pmid:3838828
Stuart MJ et al. Prostanoids in hemolytic uremic syndrome. 1985 J. Pediatr. pmid:3839015
Nigam S et al. The concentrations of 6-keto-PGF1 alpha and TXB2 in plasma samples from patients with benign and malignant tumours of the breast. 1985 Prostaglandins pmid:3839084
Hamilton TA et al. gamma-Interferon enhances the secretion of arachidonic acid metabolites from murine peritoneal macrophages stimulated with phorbol diesters. 1985 J. Immunol. pmid:3919102
Petroni A et al. Differential effects of various vasoactive drugs on basal and stimulated levels of TXB2 and 6-keto-PGF1 alpha in rat brain. 1985 Prostaglandins pmid:3839085
Zipser RD Effects of selective inhibition of thromboxane synthesis on renal function in humans. 1985 Am. J. Physiol. pmid:3839111
Kimura Y et al. Effects of stilbene derivatives on arachidonate metabolism in leukocytes. 1985 Biochim. Biophys. Acta pmid:3931689
Wargovich T et al. Reduction in blood flow in normal and narrowed coronary arteries of dogs by leukotriene C4. 1985 J. Am. Coll. Cardiol. pmid:4045029
Cerletti C et al. Aspirin kinetics and inhibition of platelet thromboxane generation-relevance for a solution of the "aspirin dilemma". 1985 Thromb. Haemost. pmid:4049312
Dejana E et al. Differential salicylate-aspirin interaction on vascular prostacyclin and platelet thromboxane synthesis in patients undergoing saphenectomy. 1985 Proc. Soc. Exp. Biol. Med. pmid:3841210
Hillbom M et al. Platelet thromboxane formation and bleeding time is influenced by ethanol withdrawal but not by cigarette smoking. 1985 Thromb. Haemost. pmid:4049313
Gairola C and Tai HH Selective inhibition of leukotriene B4 biosynthesis in rat pulmonary alveolar macrophages by dietary selenium deficiency. 1985 Biochem. Biophys. Res. Commun. pmid:2998361
Fiedler VB et al. The effects of nafazatrom in an acute occlusion-reperfusion model of canine myocardial injury. 1985 Naunyn Schmiedebergs Arch. Pharmacol. pmid:3841382
Aviram M et al. Plasma lipoproteins affect platelet malondialdehyde and thromboxane B2 production. 1985 Biochem Med pmid:4052061
Simmet T et al. Modulation of eicosanoid release from anaphylactic guinea-pig heart with 5-benzoyl-a-methyl-2-thiophene acetic acid (tiaprofenic acid). 1985 Arch Int Pharmacodyn Ther pmid:3841634
Rinaldo JE and Dauber JH Effect of methylprednisolone and of ibuprofen, a nonsteroidal antiinflammatory agent, on bronchoalveolar inflammation following endotoxemia. 1985 Circ. Shock pmid:4053294
Shingu T [Prostaglandin metabolism in ischemic brain edema]. 1985 Nihon Geka Hokan pmid:3841635
Leffler CW and Busija DW Prostanoids in cortical subarachnoid cerebrospinal fluid and pial arterial diameter in newborn pigs. 1985 Circ. Res. pmid:4053302
Tobian L et al. Prostaglandin alterations in barely hypertensive Dahl S rats. 1985 Trans. Assoc. Am. Physicians pmid:3842205
Ment LR et al. Beagle puppy model of perinatal cerebral infarction. Acute changes in regional cerebral prostaglandins during hemorrhagic hypotension. 1985 J. Neurosurg. pmid:4056903
Di Minno G et al. Platelet dysfunction in uremia. Multifaceted defect partially corrected by dialysis. 1985 Am. J. Med. pmid:3933340
Numano F et al. Coronary spasm, prostaglandin and HLA factors. 1985 Jpn. Circ. J. pmid:3855470
Purkerson ML et al. Inhibition of thromboxane synthesis ameliorates the progressive kidney disease of rats with subtotal renal ablation. 1985 Proc. Natl. Acad. Sci. U.S.A. pmid:3855542
Dempsey RJ et al. Polyamine and prostaglandin markers in focal cerebral ischemia. 1985 Neurosurgery pmid:3864030
Dahl ML and Uotila P Sodium salicylate does not prevent the inhibitory effect of indomethacin on thromboxane formation in human blood ex vivo. 1985 Prostaglandins Leukot Med pmid:3856282
Kääpä P Immunoreactive thromboxane B2 and 6-keto-prostaglandin F1 alpha in neonatal hyperbilirubinemia. 1985 Prostaglandins Leukot Med pmid:3856285
Mallarkey G and Smith GM A comparative study of the involvement of the prostaglandin H2/thromboxane A2 pathway in intravascular platelet aggregation in guinea-pigs and rats. 1985 Br. J. Pharmacol. pmid:3156648
Salmon JA et al. Evaluation of inhibitors of eicosanoid synthesis in leukocytes: possible pitfall of using the calcium ionophore A23187 to stimulate 5' lipoxygenase. 1985 Prostaglandins pmid:2988019
Murphy RC et al. Surgical delay and arachidonic acid metabolites: evidence for an inflammatory mechanism: an experimental study in rats. 1985 Br J Plast Surg pmid:3921087
Sterk PJ et al. Limited maximal airway narrowing in nonasthmatic subjects. Role of neural control and prostaglandin release. 1985 Am. Rev. Respir. Dis. pmid:2864892