Thromboxane b2
Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
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Introduction
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Thromboxane b2?
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Thromboxane b2
PubChem Associated disorders and diseases
What pathways are associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Thromboxane b2?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Thromboxane b2?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
What genes are associated with Thromboxane b2?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Thromboxane b2
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Thorngren M et al. | Thromboxane A2 in skin-bleeding-time blood and in clotted venous blood before and after administration of acetylsalicylic acid. | 1983 | Lancet | pmid:6133107 |
| Drake TS et al. | Peritoneal fluid prostanoids in unexplained infertility. | 1983 | Am. J. Obstet. Gynecol. | pmid:6614085 |
| Stenson WF and Lobos E | Inhibition of platelet thromboxane synthetase by sulfasalazine. | 1983 | Biochem. Pharmacol. | pmid:6135423 |
| Chang J et al. | Effects of thiazinamium chloride, promethazine and chlorpromazine on thromboxane B2 synthesis, phagocytosis and respiratory burst by rat alveolar macrophages. | 1983 | Biochem. Pharmacol. | pmid:6138040 |
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| Goetzl EJ et al. | Enhancement of human neutrophil adherence by synthetic leukotriene constituents of the slow-reacting substance of anaphylaxis. | 1983 | Immunology | pmid:6193056 |
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| Brox JH et al. | Effects of cod liver oil on platelets and coagulation in familial hypercholesterolemia (type IIa). | 1983 | Acta Med Scand | pmid:6340424 |
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| Buchanan MR et al. | The sex-related differences in aspirin pharmacokinetics in rabbits and man and its relationship to antiplatelet effects. | 1983 | Thromb. Res. | pmid:6221436 |
| Yamamoto S et al. | Enzyme immunoassay of thromboxane B2 and 6-keto-prostaglandin F1 alpha as a substitute for radioimmunoassay. | 1983 | Adv. Prostaglandin Thromboxane Leukot. Res. | pmid:6221523 |
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| Ito T et al. | Effects of a selective inhibitor of thromboxane synthetase (OKY-1581) in humans. | 1983 | Adv. Prostaglandin Thromboxane Leukot. Res. | pmid:6221531 |
| FitzGerald GA et al. | Aspirin inhibits endogenous prostacyclin and thromboxane biosynthesis in man. | 1983 | Adv. Prostaglandin Thromboxane Leukot. Res. | pmid:6221534 |
| Dubin NH et al. | Thromboxane production in the pregnant rat: differential recovery by platelets and uterus following aspirin administration. | 1983 | Biol. Reprod. | pmid:6626652 |
| van der Giessen WJ et al. | Acute effect of cigarette smoking on cardiac prostaglandin synthesis and platelet behavior in patients with coronary heart disease. | 1983 | Adv. Prostaglandin Thromboxane Leukot. Res. | pmid:6221546 |
| Nuotto E et al. | Effect of acetylsalicylic acid on plasma thromboxane B2 and platelet aggregation in man. | 1983 | Eur. J. Clin. Pharmacol. | pmid:6628518 |
| Abiko Y et al. | The stimulation of macrophage prostaglandin E2 and thromboxane B2 secretion by Streptococcus mutans insoluble glucans. | 1983 | FEBS Lett. | pmid:6403385 |
| Barnhart MI et al. | DDAVP: does the drug have a direct effect on the vessel wall? | 1983 | Thromb. Res. | pmid:6415852 |
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| Muccitelli RM et al. | Effect of inhibition of thromboxane production on the leukotriene D4-mediated bronchoconstriction in the guinea pig. | 1983 | Prostaglandins | pmid:6689082 |
| Dale J et al. | The effect of a thromboxane synthetase inhibitor, dazoxiben, and acetylsalicylic acid on platelet function and prostaglandin metabolism. | 1983 | Thromb. Haemost. | pmid:6689091 |
| Schleimer RP et al. | Effects of dexamethasone on mediator release from human lung fragments and purified human lung mast cells. | 1983 | J. Clin. Invest. | pmid:6134755 |
| Liu J | [Effect of Paeonia obovata 801 on metabolism of thromboxane B2 and arachidonic acid and on platelet aggregation in patients with coronary heart disease and cerebral thrombosis]. | 1983 | Zhonghua Yi Xue Za Zhi | pmid:6418338 |
| Aehringhaus U et al. | Effect of inhibition of synthesis and receptor antagonism of SRS-A in cardiac anaphylaxis. | 1983 | Br. J. Pharmacol. | pmid:6689134 |
| Kurata M | [Relation between mouse peritoneal macrophage functions and prostaglandins]. | 1983 | Rinsho Byori | pmid:6689184 |
| Maguire ED and Wallis RB | In vivo redirection of prostaglandin endoperoxides into 6-keto PGF1 alpha formation by thromboxane synthetase inhibitors in the rat. | 1983 | Thromb. Res. | pmid:6689221 |
| McDonald JW and Ali M | Recovery of cyclooxygenase activity after aspirin in populations of platelets separated on stractan density gradients. | 1983 | Prostaglandins Leukot Med | pmid:6419234 |
| Bryant RW and Hwang DH | Development of a radioimmunoassay for 15-HETE and its application to 15-HETE production by reticulocytes. | 1983 | Prostaglandins | pmid:6419285 |
| Chong KP et al. | Vasopressin stimulates thromboxane synthesis in isolated hamster hepatocytes: relation to hepatocyte calcium content. | 1983 | Prostaglandins | pmid:6419286 |
| Hartung HP et al. | Induction of thromboxane release from macrophages by anaphylatoxic peptide C3a of complement and synthetic hexapeptide C3a 72-77. | 1983 | J. Immunol. | pmid:6600482 |
| Sautebin L et al. | Preferential utilization of endogenous arachidonate by cyclo-oxygenase in incubations of human platelets. | 1983 | FEBS Lett. | pmid:6407867 |
| Zipser RD et al. | Urinary thromboxane B2 and prostaglandin E2 in the hepatorenal syndrome: evidence for increased vasoconstrictor and decreased vasodilator factors. | 1983 | Gastroenterology | pmid:6572162 |
| Schenkelaars EJ and Bonta IL | Effect of leukotriene C4 on the release of secretory products by elicited populations of rat peritoneal macrophages. | 1983 | Eur. J. Pharmacol. | pmid:6572592 |
| Rocklin RE et al. | Augmentation of prostaglandin and thromboxane production in vitro by monocytes exposed to histamine-induced suppressor factor (HSF). | 1983 | Cell. Immunol. | pmid:6573232 |
| Walinsky P et al. | Beneficial effects of ibuprofen in pacing-induced myocardial ischemia. | 1983 | Am. J. Cardiol. | pmid:6829434 |
| Gimenez T et al. | Fetal-maternal secretion of prostaglandins in the cow. | 1983 | Prostaglandins | pmid:6576447 |
| Snapper JR et al. | Effects of cyclooxygenase inhibitors on the alterations in lung mechanics caused by endotoxemia in the unanesthetized sheep. | 1983 | J. Clin. Invest. | pmid:6409930 |