Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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De Servi S et al. | Coronary vasoconstrictor response to cold pressor test in variant angina: lack of relation to intracoronary thromboxane concentrations. | 1987 | Am. Heart J. | pmid:3630891 |
Takase B et al. | Effects of bepridil on silent myocardial ischemia and eicosanoid metabolism in chronic stable angina pectoris after healing of myocardial infarction. | 1994 | Am. J. Cardiol. | pmid:8198031 |
Fulton DR et al. | Effects of current therapy of Kawasaki disease on eicosanoid metabolism. | 1988 | Am. J. Cardiol. | pmid:2454025 |
Catella-Lawson F et al. | Oral glycoprotein IIb/IIIa antagonism in patients with coronary artery disease. | 2001 | Am. J. Cardiol. | pmid:11472700 |
Hanet C et al. | Myocardial protection by intracoronary nicardipine administration during percutaneous transluminal coronary angioplasty. | 1987 | Am. J. Cardiol. | pmid:2953226 |
Faraday N et al. | Relation between atherosclerosis risk factors and aspirin resistance in a primary prevention population. | 2006 | Am. J. Cardiol. | pmid:16950183 |
Yasu T et al. | Effects of aspirin DL-lysine on thrombin generation in unstable angina pectoris. | 1993 | Am. J. Cardiol. | pmid:8480641 |
Willerson JT et al. | Potential usefulness of combined thromboxane A2 and serotonin receptor blockade for preventing the conversion from chronic to acute coronary artery disease syndromes. | 1990 | Am. J. Cardiol. | pmid:2146868 |
McDaniel HG et al. | Platelet function abnormalities in response to arachidonic acid in the acute phase of myocardial infarction. | 1983 | Am. J. Cardiol. | pmid:6416046 |
De Caterina R et al. | Inhibition of platelet function by injectable isosorbide dinitrate. | 1984 | Am. J. Cardiol. | pmid:6428211 |
Eldar M et al. | Bradykinin level in the great cardiac vein during balloon angioplasty of the left anterior descending coronary artery. | 1992 | Am. J. Cardiol. | pmid:1466338 |
Dabaghi SF et al. | Effects of low-dose aspirin on in vitro platelet aggregation in the early minutes after ingestion in normal subjects. | 1994 | Am. J. Cardiol. | pmid:7942533 |
Graziani F et al. | Thromboxane production in morbidly obese subjects. | 2011 | Am. J. Cardiol. | pmid:21439532 |
Théroux P et al. | Hemodynamic, platelet and clinical responses to prostacyclin in unstable angina pectoris. | 1990 | Am. J. Cardiol. | pmid:2109927 |
Willerson JT et al. | Conversion from chronic to acute coronary artery disease: speculation regarding mechanisms. | 1984 | Am. J. Cardiol. | pmid:6391133 |
Shen H et al. | Aspirin Resistance in healthy drug-naive men versus women (from the Heredity and Phenotype Intervention Heart Study). | 2009 | Am. J. Cardiol. | pmid:19660620 |
Lam JY et al. | Platelet aggregation, coronary artery disease progression and future coronary events. | 1994 | Am. J. Cardiol. | pmid:8109546 |
Timmermans C et al. | Ridogrel in the setting of percutaneous transluminal coronary angioplasty. | 1991 | Am. J. Cardiol. | pmid:1872272 |
Mason PJ et al. | Plasma, serum, and platelet expression of CD40 ligand in adults with cardiovascular disease. | 2005 | Am. J. Cardiol. | pmid:16275179 |
Rehr RB et al. | Mechanism of nitroglycerin-induced coronary dilatation: lack of relation to intracoronary thromboxane concentrations. | 1984 | Am. J. Cardiol. | pmid:6437206 |