Thromboxane b2
Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
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Introduction
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Thromboxane b2?
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Thromboxane b2
PubChem Associated disorders and diseases
What pathways are associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Thromboxane b2?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Thromboxane b2?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
What genes are associated with Thromboxane b2?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Thromboxane b2
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Feldman M and Cryer B | Aspirin absorption rates and platelet inhibition times with 325-mg buffered aspirin tablets (chewed or swallowed intact) and with buffered aspirin solution. | 1999 | Am. J. Cardiol. | pmid:10468077 |
| Gurbel PA et al. | Plasma thromboxane and prostacyclin are linear related and increased in patients presenting with acute myocardial infarction. | 1999 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10477035 |
| Li D et al. | The association of diet and thrombotic risk factors in healthy male vegetarians and meat-eaters. | 1999 | Eur J Clin Nutr | pmid:10477247 |
| Fujimoto Y et al. | Sphingomyelin inhibits platelet 12-lipoxygenase activity. | 1999 | Eur. J. Pharmacol. | pmid:10478636 |
| Zaitsu M et al. | Induction of cytosolic phospholipase A2 and prostaglandin H2 synthase-2 by lipopolysaccharide in human polymorphonuclear leukocytes. | 1999 | Eur. J. Haematol. | pmid:10480288 |
| Nawarskas JJ et al. | Effect of aspirin on blood pressure in hypertensive patients taking enalapril or losartan. | 1999 | Am. J. Hypertens. | pmid:10480471 |
| Nishimaki S and Seki K | An imbalance between prostacyclin and thromboxane in relation to cerebral blood flow in neonates with maternal preeclampsia. | 1999 | Prostaglandins Other Lipid Mediat. | pmid:10482286 |
| Obata T et al. | Simultaneous assay of prostaglandins and thromboxane in the cerebrospinal fluid by gas chromatography-mass spectrometry-selected ion monitoring. | 1999 | J. Chromatogr. B Biomed. Sci. Appl. | pmid:10491991 |
| Fuglsang J et al. | Intravenous acetylsalicylic acid, magnesium and their combination in experimental arterial thrombosis in rats. | 1999 | Blood Coagul. Fibrinolysis | pmid:10493216 |
| Fruzzetti F et al. | Platelet-vessel wall interactions with third-generation oral contraceptives: no evidence of detrimental effects. | 1999 | Thromb. Haemost. | pmid:10494782 |
| Barchasz E et al. | Interleukin-1beta-induced hyperresponsiveness to [Sar9,Met(O2)11]substance P in isolated human bronchi. | 1999 | Eur. J. Pharmacol. | pmid:10499376 |
| Tanus-Santos JE et al. | Inhaled nitric oxide improves hemodynamics during a venous air infusion (VAI) in dogs. | 1999 | Intensive Care Med | pmid:10501756 |
| Gonchar M et al. | Kinetics of prostanoid synthesis by macrophages is regulated by arachidonic acid sources. | 1999 | Eur. J. Biochem. | pmid:10504410 |
| Gust R et al. | Role of cyclooxygenase-2 in oleic acid-induced acute lung injury. | 1999 | Am. J. Respir. Crit. Care Med. | pmid:10508803 |
| Thakur V et al. | Antihypertensive effect of the combination of fosinopril and HCTZ is resistant to interference by nonsteroidal antiinflammatory drugs. | 1999 | Am. J. Hypertens. | pmid:10509552 |
| Yang SY and Gao ZX | Determination and clinical significance of plasma levels of prostaglandins in patients with acute brain injury. | 1999 | Surg Neurol | pmid:10511080 |
| Cryer B et al. | Effects of cutaneous aspirin on the human stomach and duodenum. | 1999 Sep-Oct | Proc. Assoc. Am. Physicians | pmid:10519166 |
| Véricel E et al. | The influence of low intake of n-3 fatty acids on platelets in elderly people. | 1999 | Atherosclerosis | pmid:10525140 |
| Serebruany VL et al. | Effects of a novel Mac-1 inhibitor, NPC 15669, on hemostatic parameters during preconditioned myocardial infarction. | 1999 | Life Sci. | pmid:10530802 |
| Chou TC et al. | Antiplatelet effect of amlodipine: a possible mechanism through a nitric oxide-mediated process. | 1999 | Biochem. Pharmacol. | pmid:10535758 |
| Pearl JM et al. | Effect of modified ultrafiltration on plasma thromboxane B2, leukotriene B4, and endothelin-1 in infants undergoing cardiopulmonary bypass. | 1999 | Ann. Thorac. Surg. | pmid:10543508 |
| de Meijer A et al. | Meloxicam, 15 mg/day, spares platelet function in healthy volunteers. | 1999 | Clin. Pharmacol. Ther. | pmid:10546927 |
| Reeves JH et al. | Continuous plasmafiltration in sepsis syndrome. Plasmafiltration in Sepsis Study Group. | 1999 | Crit. Care Med. | pmid:10548188 |
| Nemcova S et al. | Cyclic nucleotides and production of prostanoids in human varicose veins. | 1999 | J. Vasc. Surg. | pmid:10550185 |
| Hirakata H et al. | Propofol has both enhancing and suppressing effects on human platelet aggregation in vitro. | 1999 | Anesthesiology | pmid:10551587 |
| Heller A et al. | Pancreatitis-associated protein protects the lung from leukocyte-induced injury. | 1999 | Anesthesiology | pmid:10551593 |
| Titos E et al. | Hepatocytes are a rich source of novel aspirin-triggered 15-epi-lipoxin A(4). | 1999 | Am. J. Physiol. | pmid:10564079 |
| Castellani S et al. | Impaired renal adaptation to stress in the elderly with isolated systolic hypertension. | 1999 | Hypertension | pmid:10567190 |
| Vijaya Kumar M et al. | The anhydrous milk fat, ghee, lowers serum prostaglandins and secretion of leukotrienes by rat peritoneal macrophages. | 1999 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10574649 |
| Gallery ED et al. | In vitro human decidual endothelial cell thromboxane secretion in preeclampsia is not abnormal. | 1999 | Hypertens Pregnancy | pmid:10586525 |
| Pirich C et al. | Effects of fish oil supplementation on platelet survival and ex vivo platelet function in hypercholesterolemic patients. | 1999 | Thromb. Res. | pmid:10588465 |
| Pavord ID et al. | Induced sputum eicosanoid concentrations in asthma. | 1999 | Am. J. Respir. Crit. Care Med. | pmid:10588604 |
| Mizugaki M et al. | Monitoring of the thromboxane A2/prostacyclin ratio in the urine of patients with retinal vascular occlusion through the low-dose-aspirin therapy using the gas chromatography/selected ion monitoring method. | 1999 | Prostaglandins Other Lipid Mediat. | pmid:10593167 |
| Hishinuma T et al. | Urinary thromboxane A2/prostacyclin balance reflects the pathological state of a diabetic. | 1999 | Prostaglandins Other Lipid Mediat. | pmid:10593168 |
| Hoch B and Bernhard M | Reduced prostacyclin to thromboxane A2 ratio is correlated with central apneas in preterm infants. | 1999 | Prostaglandins Other Lipid Mediat. | pmid:10593170 |
| Kohda N et al. | Effect of cilostazol, a phosphodiesterase III inhibitor, on experimental thrombosis in the porcine carotid artery. | 1999 | Thromb. Res. | pmid:10593428 |
| Chou TC and Li CY | Inhibitory mechanisms of dantrolene on platelet aggregation. | 1999 | Thromb. Res. | pmid:10593433 |
| De La Cruz JP et al. | Antiplatelet effect of the anaesthetic drug propofol: influence of red blood cells and leucocytes. | 1999 | Br. J. Pharmacol. | pmid:10602334 |
| Reis F et al. | The peripheral serotonergic system and platelet aggregation in cyclosporin A-induced hypertensive rats. | 1999 | Thromb. Res. | pmid:10605951 |
| Eldor A et al. | A chronic hypercoagulable state in patients with beta-thalassaemia major is already present in childhood. | 1999 | Br. J. Haematol. | pmid:10606878 |
| Ferro D et al. | Determinants of enhanced thromboxane biosynthesis in patients with systemic lupus erythematosus. | 1999 | Arthritis Rheum. | pmid:10616019 |
| Uriu K et al. | Effect of acute thromboxane A2 inhibition on the renal hemodynamics in a spontaneously non-insulin-dependent diabetic rat, Otsuka Long-Evans Tokushima Fatty rat. | 1999 Jul-Aug | J. Diabetes Complicat. | pmid:10616856 |
| Tanus-Santos JE et al. | The hemodynamic effects of endothelin receptor antagonism during a venous air infusion in dogs. | 2000 | Anesth. Analg. | pmid:10624986 |
| Dahlin KL et al. | Amitriptyline-induced release of endothelin-1 in isolated perfused and ventilated rat lungs. | 1999 | Pharmacol. Toxicol. | pmid:10628905 |
| Perneby C et al. | Optimization of an enzyme immunoassay for 11-dehydro-thromboxane B(2) in urine: comparison with GC-MS. | 1999 | Thromb. Res. | pmid:10632465 |
| Miura M and Kurimoto F | [Thromboxane B2 (TXB2)]. | 1999 | Nippon Rinsho | pmid:10635957 |
| González E et al. | Evolution of streptozotocin-pancreatic damage in the rat: modulatory effect of endothelins on the nitridergic and prostanoid pathway. | 1999 | Nitric Oxide | pmid:10637124 |
| Stewart KG et al. | Estrogen decreases prostaglandin H synthase products from endothelial cells. | 1999 Nov-Dec | J. Soc. Gynecol. Investig. | pmid:10643586 |
| Gajdos M et al. | [The effect of monotherapy with ciprofibrate and in combination with acetylsalicylic acid on the spectrum of lipids, thromboxane and fibrinogen in patients with atherosclerosis and hyperlipoproteinemia]. | 1999 | Bratisl Lek Listy | pmid:10645034 |
| Montini G et al. | Renal glomerular response to the inhibition of prostaglandin E2 synthesis and protein loading after the relief of unilateral ureteropelvic junction obstruction. | 2000 | J. Urol. | pmid:10647684 |
| Chou TC et al. | Mechanism of inhibition of platelet aggregation by HCL-31D. | 2000 | Eur. J. Pharmacol. | pmid:10650152 |
| Landoni MF et al. | Enantiospecific pharmacokinetics and pharmacodynamics of ketoprofen in sheep. | 1999 | J. Vet. Pharmacol. Ther. | pmid:10651463 |
| Hansen JM et al. | Effects of nitric oxide blockade and cyclosporin A on cardiovascular and renal function in normal man. | 1999 | J. Hypertens. | pmid:10658936 |
| Matsumoto H and Nakao T | Elevated urinary excretion of thromboxane B2 in adults with minimal-change nephrotic syndrome. | 2000 | Clin. Nephrol. | pmid:10661487 |
| Leese PT et al. | Effects of celecoxib, a novel cyclooxygenase-2 inhibitor, on platelet function in healthy adults: a randomized, controlled trial. | 2000 | J Clin Pharmacol | pmid:10664917 |
| Okumura M et al. | Renal production of thromboxane and prostaglandins in a rat model of type 2 diabetes. | 2000 | Life Sci. | pmid:10670825 |
| Wu TM et al. | Inhibitory effect of hexapeptide (RGRHGD) on platelet aggregation. | 2000 | Thromb. Res. | pmid:10674405 |
| De La Cruz JP et al. | Effect of DT-TX 30, a combined thromboxane synthase inhibitor and thromboxane receptor antagonist, on retinal vascularity in experimental diabetes mellitus. | 2000 | Thromb. Res. | pmid:10680643 |
| Zeng W et al. | [Relationship between PGI2, TXA2 and threatened preterm]. | 1998 | Hua Xi Yi Ke Da Xue Xue Bao | pmid:10684102 |
| Nagano K et al. | Prostanoids regulate proliferation of vascular smooth muscle cells induced by arginine vasopressin. | 2000 | Eur. J. Pharmacol. | pmid:10686292 |
| Tegeder I et al. | Effects of selective and unselective cyclooxygenase inhibitors on prostanoid release from various rat organs. | 2000 | J. Pharmacol. Exp. Ther. | pmid:10688636 |
| Nosál R and Jancinová V | Nonreceptor interactions in the pharmacology of blood platelets. | 1999 | Gen. Physiol. Biophys. | pmid:10703730 |
| Suntres ZE and Shek PN | Prophylaxis against lipopolysaccharide-induced lung injuries by liposome-entrapped dexamethasone in rats. | 2000 | Biochem. Pharmacol. | pmid:10704946 |
| Weber AA et al. | 40 mg of aspirin are not sufficient to inhibit platelet function under conditions of limited compliance. | 2000 | Thromb. Res. | pmid:10709913 |
| Okada S et al. | Perfusion of the hypothalamic paraventricular nucleus with N-methyl-D-aspartate produces thromboxane A2 and centrally activates adrenomedullary outflow in rats. | 2000 | Neuroscience | pmid:10717438 |
| Zaitsu M et al. | Ulinastatin, an elastase inhibitor, inhibits the increased mRNA expression of prostaglandin H2 synthase-type 2 in Kawasaki disease. | 2000 | J. Infect. Dis. | pmid:10720537 |
| Pärsson HN et al. | Maintaining carotid flow by shunting during carotid endarterectomy diminishes the inflammatory response mediating ischaemic brain injury. | 2000 | Eur J Vasc Endovasc Surg | pmid:10727360 |
| Jacobi K et al. | Plasma levels of eicosanoids after transfusion of intraoperatively salvaged blood. | 2000 | Vox Sang. | pmid:10729809 |
| Homoncik M et al. | Monitoring of aspirin (ASA) pharmacodynamics with the platelet function analyzer PFA-100. | 2000 | Thromb. Haemost. | pmid:10739392 |
| Schweizer A et al. | Aprotinin does not impair renal haemodynamics and function after cardiac surgery. | 2000 | Br J Anaesth | pmid:10740541 |
| Nenci GG and Paliani U | [Diabetes, coagulation and vascular events]. | 2000 | Recenti Prog Med | pmid:10748654 |
| Bailey SR et al. | Actions and interactions of ADP, 5- HT, histamine and PAF on equine platelets. | 2000 | Res. Vet. Sci. | pmid:10756136 |
| Liao CH et al. | Antiplatelet effect of marchantinquinone, isolated from Reboulia hemisphaerica, in rabbit washed platelets. | 2000 | J. Pharm. Pharmacol. | pmid:10757426 |
| Prieto MA et al. | Influence of triflusal on platelet activation after coronary artery bypass graft. | 2000 | Blood Coagul. Fibrinolysis | pmid:10759013 |
| Heller A et al. | The complement regulators C1 inhibitor and soluble complement receptor 1 attenuate acute lung injury in rabbits. | 2000 | Shock | pmid:10774617 |
| Agnoli GC et al. | Renal synthesis of prostacyclin and thromboxane in healthy women: differential effects of a short-term saline loading. | 2000 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10780876 |
| Jacobs C et al. | 1-imidazolyl(alkyl)-substituted di- and tetrahydroquinolines and analogues: syntheses and evaluation of dual inhibitors of thromboxane A(2) synthase and aromatase. | 2000 | J. Med. Chem. | pmid:10794700 |
| Zhao S et al. | Glioma prostaglandin levels correlate with brain edema. | 1998 | J. Tongji Med. Univ. | pmid:10806839 |
| Wakitani K et al. | JTE-522 selectively inhibits cyclooxygenase-2-derived prostaglandin production in inflammatory tissues. | 2000 | Inflamm. Res. | pmid:10807499 |
| Gardan B et al. | Vasoconstrictor effects of iso-prostaglandin F2alpha type-III (8-iso-prostaglandin F2alpha) on human saphenous veins. | 2000 | J. Cardiovasc. Pharmacol. | pmid:10813374 |
| Jacobi KE et al. | Determination of eicosanoid and cytokine production in salvaged blood, stored red blood cell concentrates, and whole blood. | 2000 | J Clin Anesth | pmid:10818321 |
| Tanus-Santos JE et al. | Endothelin ET(A) receptor antagonism attenuates the pressor effects of nicotine in rats. | 2000 | Eur. J. Pharmacol. | pmid:10822051 |
| Turpeinen AM et al. | Similar responses in hemostatic factors after consumption of wholemeal rye bread and low-fiber wheat bread. | 2000 | Eur J Clin Nutr | pmid:10822290 |
| Romano M et al. | Fluvastatin reduces soluble P-selectin and ICAM-1 levels in hypercholesterolemic patients: role of nitric oxide. | 2000 | J. Investig. Med. | pmid:10822898 |
| Sheu JR et al. | Mechanisms involved in the antiplatelet activity of Staphylococcus aureus lipoteichoic acid in human platelets. | 2000 | Thromb. Haemost. | pmid:10823277 |
| Nosál' R et al. | Chloroquine: a multipotent inhibitor of human platelets in vitro. | 2000 | Thromb. Res. | pmid:10828481 |
| Maccarrone M et al. | Activation of different lipoxygenase isozymes induces apoptosis in human erythroleukemia and neuroblastoma cells. | 2000 | Biochem. Biophys. Res. Commun. | pmid:10833416 |
| Semenov AV et al. | [Soluble P-selectin - a marker of platelet activation and vessel wall injury: increase of soluble P-selectin in plasma of patients with myocardial infarction, massive atherosclerosis and primary pulmonary hypertension]. | 2000 | Ter. Arkh. | pmid:10833791 |
| Numminen H et al. | The effect of acute ingestion of a large dose of alcohol on the hemostatic system and its circadian variation. | 2000 | Stroke | pmid:10835443 |
| Sakamoto K et al. | An imbalance in plasma prostanoids in patients with Raynaud's phenomenon and pulmonary vasospasm. | 1999 | Eur. Respir. J. | pmid:10836338 |
| Cracowski JL et al. | Human internal mammary artery contraction by isoprostaglandin f(2alpha) type-III [8-iso-prostaglandin F(2alpha)]. | 2000 | Eur. J. Pharmacol. | pmid:10844110 |
| Rioja I et al. | An anti-inflammatory ditriazine inhibiting leukocyte functions and expression of inducible nitric oxide synthase and cyclo-oxygenase-2. | 2000 | Eur. J. Pharmacol. | pmid:10844115 |
| Tran HS et al. | The cardiovascular hemodynamics and leukotriene kinetics during prostacyclin and anti-prostacyclin antibody infusions in septic shock. | 2000 | Shock | pmid:10847636 |
| Carty E et al. | Ridogrel, a dual thromboxane synthase inhibitor and receptor antagonist: anti-inflammatory profile in inflammatory bowel disease. | 2000 | Aliment. Pharmacol. Ther. | pmid:10848666 |
| Theriot JA et al. | Dietary chloride does not correlate with urinary thromboxane in deoxycorticosterone acetate-treated rats. | 2000 | J. Lab. Clin. Med. | pmid:10850649 |
| Mizugaki M | [Microdetermination of eicosanoids using mass spectrometry]. | 2000 | Nippon Yakurigaku Zasshi | pmid:10876809 |
| Depré M et al. | Pharmacokinetics, COX-2 specificity, and tolerability of supratherapeutic doses of rofecoxib in humans. | 2000 | Eur. J. Clin. Pharmacol. | pmid:10877012 |
| Moon CH et al. | Mechanism for antiplatelet effect of onion: AA release inhibition, thromboxane A(2)synthase inhibition and TXA(2)/PGH(2)receptor blockade. | 2000 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10883058 |
| Lasserre B et al. | Modifications in the TXA(2) and PGI(2) plasma levels and some other biochemical parameters during the initiation and development of non-insulin-dependent diabetes mellitus (NIDDM) syndrome in the rabbit. | 2000 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10883059 |
| Bereczki C et al. | The roles of platelet function, thromboxane, blood lipids and nitric oxide in hypertension of children and adolescents. | 2000 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10883060 |