Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Burch RM and Halushka PV | Thromboxane and stable prostaglandin endoperoxide analogs stimulate water permeability in the toad urinary bladder. | 1980 | J. Clin. Invest. | pmid:6777398 |
Galli C et al. | Dietary essential fatty acids, tissue fatty acids and prostaglandin synthesis. | 1980 | Prog Food Nutr Sci | pmid:6779348 |
Best LC et al. | Studies on the role of calcium in the control of thromboxane B2 production. | 1980 | Artery | pmid:6783015 |
Challis JR and Patrick JE | The production of prostaglandins and thromboxanes in the feto-placental unit and their effects on the developing fetus. | 1980 | Semin. Perinatol. | pmid:6992278 |
Patrono C et al. | Radioimmunoassay measurement of stable metabolites of platelet arachidonic acid: a convenient method for the in vitro and ex vivo evaluation of cyclo-oxygenase inhibitors. | 1980 | Agents Actions Suppl. | pmid:6787852 |
Salmon JA | Analysis of arachidonic acid metabolites by radioimmunoassay and physicochemical methods. | 1980 | Mater Med Pol | pmid:7019588 |
Mathé AA et al. | Increased content of immunoreactive prostaglandin E in cerebrospinal fluid of patients with schizophrenia. | 1980 | Lancet | pmid:6101355 |
Mestel F et al. | Severe bleeding associated with defective thromboxane synthetase. | 1980 | Lancet | pmid:6101498 |
Ohuchi K et al. | Prostaglandin production by minced carrageenin granuloma tissue of rats and its inhibition by dexamethasone and cycloheximide. | 1980 | Prostaglandins Med | pmid:6893750 |
Chiabrando C et al. | Quantitative determination of 6-keto-PGF1 alpha released by rat aorta: comparison of mass fragmentography and high resolution gas chromatography with electron capture detection. | 1980 | Prostaglandins | pmid:6894036 |
Ellwood DA et al. | Specific changes in the in vitro production of prostanoids by the ovine cervix at parturition. | 1980 | Prostaglandins | pmid:7384553 |
Lagarde M et al. | Nicergoline, an anti-aggregating agent which inhibits release of arachidonic acid from human platelet phospholipids. | 1980 | Prostaglandins | pmid:7384555 |
Patrono C et al. | Radioimmunoassay of serum thromboxane B2: a simple method of assessing pharmacologic effects on platelet function. | 1980 | Adv Prostaglandin Thromboxane Res | pmid:7386257 |
Langs DA et al. | Thromboxane molecules are not hairpin conformers. | 1980 | Adv Prostaglandin Thromboxane Res | pmid:7386281 |
Bailey JM | Essential fatty acid requirements and metabolism of cells in tissue culture. | 1980 | Adv Prostaglandin Thromboxane Res | pmid:7386288 |
Moretti RL and Lin CY | Coronary vasoconstrictor extracted from blood plasma stimulates platelet lipoxidase activity. | 1980 | Prostaglandins | pmid:6770419 |
Maggi FM et al. | Prostaglandin synthetase activity in vascular tissue of male and female rats. | 1980 | Prostaglandins | pmid:6770422 |
Feinstein MB et al. | Serine-esterase (protease) inhibitors block stimulus-induced mobilization of arachidonate in platelets. | 1980 | Adv Prostaglandin Thromboxane Res | pmid:6770602 |
Bone EA et al. | The effects of strontium and calcium ions on 5-hydroxytryptamine secretion and thromboxane B2 biosynthesis in washed human platelets. | 1980 | Biochem. Soc. Trans. | pmid:7450206 |
Mitchell MD | Prostaglandins at parturition and in the neonatal infant. | 1980 | Biochem. Soc. Trans. | pmid:7450282 |