Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

Cross Reference

Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Airway Obstruction D000402 13 associated lipids
Uremia D014511 33 associated lipids
Stomach Ulcer D013276 75 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Hypoxia D000860 23 associated lipids
Graft Occlusion, Vascular D006083 11 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Adenocarcinoma D000230 166 associated lipids
Ovarian Neoplasms D010051 10 associated lipids
Pain D010146 64 associated lipids
Contusions D003288 3 associated lipids
Autoimmune Diseases D001327 27 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Lung Diseases D008171 37 associated lipids
Lung Neoplasms D008175 171 associated lipids
Wounds and Injuries D014947 20 associated lipids
Pleurisy D010998 20 associated lipids
Burns D002056 34 associated lipids
Inflammation D007249 119 associated lipids
Reperfusion Injury D015427 65 associated lipids
Colitis D003092 69 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Diabetic Nephropathies D003928 39 associated lipids
Diabetic Retinopathy D003930 39 associated lipids
Cattle Diseases D002418 24 associated lipids
Fatty Liver D005234 48 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Mammary Neoplasms, Experimental D008325 67 associated lipids
Body Weight D001835 333 associated lipids
Edema D004487 152 associated lipids
Arthritis D001168 41 associated lipids
Arthritis, Experimental D001169 24 associated lipids
Hypotension D007022 41 associated lipids
Acute Kidney Injury D058186 34 associated lipids
Gastritis D005756 27 associated lipids
Heart Failure D006333 36 associated lipids
Pulmonary Edema D011654 23 associated lipids
Pulmonary Embolism D011655 5 associated lipids
Coronary Disease D003327 70 associated lipids
Liver Cirrhosis, Experimental D008106 36 associated lipids
Hypersensitivity D006967 22 associated lipids
Hypothyroidism D007037 32 associated lipids
Rhinitis D012220 10 associated lipids
Hypercapnia D006935 5 associated lipids
Arterial Occlusive Diseases D001157 12 associated lipids
Pain, Postoperative D010149 13 associated lipids
Per page 10 20 50 100 | Total 293

PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

Download all related citations
Per page 10 20 50 100 | Total 6367
Authors Title Published Journal PubMed Link
Malini PL et al. Thromboxane antagonism and cough induced by angiotensin-converting-enzyme inhibitor. 1997 Lancet pmid:9217714
Nanji AA et al. Cholesterol supplementation prevents necrosis and inflammation but enhances fibrosis in alcoholic liver disease in the rat. 1997 Hepatology pmid:9214456
Yan Y et al. [Study on mechanism of eye-signs in blood stasis syndrome]. 1996 Zhongguo Zhong Xi Yi Jie He Za Zhi pmid:9206243
Hellyer PW et al. Effect of NG-nitro-L-arginine-methyl-ester on cardiopulmonary function and biosynthesis of cyclooxygenase products during porcine endotoxemia. 1997 Crit. Care Med. pmid:9201060
Carty TJ et al. Tenidap inhibits 5-lipoxygenase product formation in vitro, but this activity is not observed in three animal models. 1997 Inflamm. Res. pmid:9197987
Hato T et al. Outside-in signaling from integrin alpha IIb beta 3 into platelets in the absence of agonist-induced signaling. 1997 Int. J. Hematol. pmid:9195778
Cook ME et al. Comparative effects of nabumetone, sulindac, and ibuprofen on renal function. 1997 J. Rheumatol. pmid:9195523
Fujinishi A et al. Effects of nisoldipine on cytosolic calcium, platelet aggregation, and coagulation/fibrinolysis in patients with coronary artery disease. 1997 Angiology pmid:9194537
Ali M et al. Synthesis of prostaglandin D2 and thromboxane B2 by human platelets. 1977 Thromb. Res. pmid:918907
Oosaki R et al. Urinary leukotriene E4 and 11-dehydrothromboxane B2 in patients with aspirin-sensitive asthma. 1997 Allergy pmid:9188934
Murthy S et al. Ischemia/reperfusion injury in the rat colon. 1997 Inflammation pmid:9187961
Bräutigam R et al. Arachidonic acid of platelet phospholipids is decreased after extracorporeal removal of plasma low density lipoproteins in patients with familial hypercholesterolemia. 1997 Atherosclerosis pmid:9180250
Vila V et al. Fibrinopeptide A release from intraplatelet fibrinogen is related to thrombin platelet activation. 1997 Thromb. Res. pmid:9175247
Barbieri B et al. p-Aminobenzoic acid, but not its metabolite p-acetamidobenzoic acid, inhibits thrombin induced thromboxane formation in human platelets in a non NSAID like manner. 1997 Thromb. Res. pmid:9175234
Oguogho A et al. Chloroquine minimizes sampling artefacts for radioimmunological determination of thromboxane B2 in plasma. 1997 Prostaglandins Leukot. Essent. Fatty Acids pmid:9175176
Klosterhalfen B et al. The influence of heat shock protein 70 induction on hemodynamic variables in a porcine model of recurrent endotoxemia. 1997 Shock pmid:9165671
Low-dose aspirin in polycythaemia vera: a pilot study. Gruppo Italiano Studio Policitemia (GISP). 1997 Br. J. Haematol. pmid:9163613
Shimada Y et al. Role of platelets in myocardial ischemia-reperfusion injury in dogs. 1997 Jpn. Circ. J. pmid:9152773
Closa D et al. Prostanoids and free radicals in Cl4C-induced hepatotoxicity in rats: effect of astilbin. 1997 Prostaglandins Leukot. Essent. Fatty Acids pmid:9150380
Sinzinger H et al. PGE1-induced arterial thromboresistance is a vascular property as identified by cross-perfusion technique. 1997 Prostaglandins Leukot. Essent. Fatty Acids pmid:9150379
Zhang T et al. Effects of the incubation of long-chain polyunsaturated fatty acids on platelet lipids and thromboxane release. 1997 Prostaglandins Leukot. Essent. Fatty Acids pmid:9150370
Kraft M et al. The effect of salmeterol on nocturnal symptoms, airway function, and inflammation in asthma. 1997 Chest pmid:9149578
Roberts LJ et al. Metabolism of thromboxane B2 in man. Identification of the major urinary metabolite. 1977 J. Biol. Chem. pmid:914816
Bishop-Bailey D et al. Characterization of the induction of nitric oxide synthase and cyclo-oxygenase in rat aorta in organ culture. 1997 Br. J. Pharmacol. pmid:9146896
Riendeau D et al. Biochemical and pharmacological profile of a tetrasubstituted furanone as a highly selective COX-2 inhibitor. 1997 Br. J. Pharmacol. pmid:9146894
Henrion D et al. Alteration of flow-induced dilatation in mesenteric resistance arteries of L-NAME treated rats and its partial association with induction of cyclo-oxygenase-2. 1997 Br. J. Pharmacol. pmid:9146891
Todd MK et al. Comparison of methods for evaluating exercise-induced changes in thromboxane B2 and beta-thromboglobulin. 1997 Med Sci Sports Exerc pmid:9140910
Olson KR et al. Cardiovascular effects of homologous bradykinin in rainbow trout. 1997 Am. J. Physiol. pmid:9140009
Oelkers R et al. Disposition and effects of flurbiprofen enantiomers in human serum and blister fluid. 1997 Br J Clin Pharmacol pmid:9131946
He CF et al. Postural vasoregulation and mediators of reperfusion injury in venous ulceration. 1997 J. Vasc. Surg. pmid:9129619
Cheng Z et al. Pharmacokinetic and pharmacodynamic studies on phenylbutazone and oxyphenbutazone in goats. 1997 Vet. Rec. pmid:9123796
Yagi T et al. Hepatropic soluble vitamin E derivative EPC-K1 prevents warm ischemia/reperfusion injury of non-heart-beating donor liver transplantation in pigs. 1997 Feb-Mar Transplant. Proc. pmid:9123352
Suehiro T et al. Value of caval effluent in predicting early graft function after orthotopic liver transplantation. 1997 Feb-Mar Transplant. Proc. pmid:9123086
Ishine N et al. Hemodynamic analysis of post-reperfusion syndrome and the effect of preventing this syndrome using thromboxane A2 synthetase inhibitor (OKY-046) in swine liver transplantation. 1997 Feb-Mar Transplant. Proc. pmid:9123045
Teraoka S et al. Multicenter trial of the therapeutic effect of a newly developed antiplatelet agent, satigrel, on biopsy-proven chronic rejection after kidney transplantation. 1997 Feb-Mar Transplant. Proc. pmid:9122990
Shinohara M et al. [Responses to surgical stress in blood coagulation and fibrinolysis, platelet counts and thromboxane B2 after esophageal cancer operation]. 1997 Rinsho Byori pmid:9121003
Aibiki M and Cook JA Ulinastatin, a human trypsin inhibitor, inhibits endotoxin-induced thromboxane B2 production in human monocytes. 1997 Crit. Care Med. pmid:9118658
Murota SI et al. The effects of thromboxane B2 and 6-ketoprostaglandin F1alpha on cultured fibroblasts. 1977 Biochim. Biophys. Acta pmid:911847
Cambridge H et al. Plasma thromboxane B2 levels in horses experimentally infected with Strongylus vulgaris. 1989 Equine Vet J Suppl pmid:9118097
Mitra A et al. Thromboxane-mediated alveolar responses to acute obstruction of the pulmonary vasculature. 1997 Am. J. Respir. Crit. Care Med. pmid:9117035
Hayball PJ et al. The influence of renal function on the enantioselective pharmacokinetics and pharmacodynamics of ketoprofen in patients with rheumatoid arthritis. 1993 Br J Clin Pharmacol pmid:9114902
Brus F et al. Number and activation of circulating polymorphonuclear leukocytes and platelets are associated with neonatal respiratory distress syndrome severity. 1997 Pediatrics pmid:9113943
Barry MC et al. Immunological and physiological responses to aortic surgery: effect of reperfusion on neutrophil and monocyte activation and pulmonary function. 1997 Br J Surg pmid:9112905
Zeltsman D et al. Pathophysiologic plasma levels of leukotriene C4 in relation to the hemodynamic dysfunction and mediator release of graded bacteremia. 1997 Shock pmid:9110414
Tomas-Barberan S et al. Effect of diclofenac on prostaglandin liberation in the rabbit after photorefractive keratectomy. 1997 Mar-Apr J Refract Surg pmid:9109071
Yasui K et al. Involvement of thromboxane A2 in antigen-induced nasal blockage in guinea pigs. 1997 Int. Arch. Allergy Immunol. pmid:9104797
Cueto SM et al. beta-Carotene attenuates peroxide-induced vasoconstriction in the human placenta. 1997 Mar-Apr J. Soc. Gynecol. Investig. pmid:9101463
Shellhaas CS et al. Intravillous eicosanoid compartmentalization and regulation of placental blood flow. 1997 Mar-Apr J. Soc. Gynecol. Investig. pmid:9101462
Rocha FA et al. PAF modulates eicosanoids and TNF release in immune-complex arthritis in rats. 1997 J Lipid Mediat Cell Signal pmid:9101418
Kume S [Evaluation and problems on platelet function tests]. 1997 Nippon Rinsho pmid:9097565