Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Disseminated Intravascular Coagulation D004211 7 associated lipids
Glomerulonephritis, IGA D005922 7 associated lipids
Coronary Thrombosis D003328 7 associated lipids
Femoral Fractures D005264 7 associated lipids
Varicose Veins D014648 7 associated lipids
Behcet Syndrome D001528 7 associated lipids
Rhinitis, Allergic, Seasonal D006255 7 associated lipids
Agranulocytosis D000380 7 associated lipids
Aortic Aneurysm D001014 8 associated lipids
Lupus Nephritis D008181 8 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

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Per page 10 20 50 100 | Total 6367
Authors Title Published Journal PubMed Link
Burch RM and Halushka PV Thromboxane and stable prostaglandin endoperoxide analogs stimulate water permeability in the toad urinary bladder. 1980 J. Clin. Invest. pmid:6777398
Galli C et al. Dietary essential fatty acids, tissue fatty acids and prostaglandin synthesis. 1980 Prog Food Nutr Sci pmid:6779348
Best LC et al. Studies on the role of calcium in the control of thromboxane B2 production. 1980 Artery pmid:6783015
Silver MJ et al. A model system for studying initial events in atherosclerosis. 1980 Artery pmid:7000044
Fitzpatrick TM et al. Tromboxane B2 inhibits the pulmonary inactivation of prostaglandin E2 in the dog. 1980 Br. J. Pharmacol. pmid:7000216
Poyser NL and Scott FM Prostaglandin and thromboxane production by the rat uterus and ovary in vitro during the oestrous cycle. 1980 J. Reprod. Fertil. pmid:7001011
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Subbiah MT et al. Enhancement of thrombocyte aggregation and thromboxane B2 synthesis by diethylstilbestrol. 1980 Pharmacology pmid:7220591
Ali AE et al. Prostaglandin and thromboxane production by fibroblasts and vascular endothelial cells. 1980 Prostaglandins pmid:7008090
Ohtsu E and Matsuzawa T Metabolic alterations in the endogenous formation of 6 keto-prostaglandin F1 alpha, thromboxane B2 and prostaglandin E2 in the brain-stem of stroke-resistant spontaneously hypertensive rats. 1980 J. Nutr. Sci. Vitaminol. pmid:7229740
Vargaftig BB et al. Activation of guinea-pig platelets induced by convulxin, a substance extracted from the venom of Crotalus durissus cascavella. 1980 Eur. J. Pharmacol. pmid:7009169
Giri SN and Krishna GA Development of a dual isotopes techniques and two-stage column chromatography to characterize the prostaglandin F2alpha, E2 and Thromboxane B2 formed by the guinea pig lung. 1980 J Pharmacol Methods pmid:7009992
Mathé AA et al. Increased content of immunoreactive prostaglandin E in cerebrospinal fluid of patients with schizophrenia. 1980 Lancet pmid:6101355
Harris RH et al. Relationship of TXB2 and 6-keto PGF1 alpha to the hemodynamic changes during baboon endotoxic shock. 1980 Adv Prostaglandin Thromboxane Res pmid:6768234
Jécsai G and Bagdány S Quantitative determination of thromboxane synthesis in blood samples by video-densitometry. 1980 Acta Biochim. Biophys. Acad. Sci. Hung. pmid:7282294
Hwang DH Aggregation and inhibition of rat platelets, and the formation of endoperoxide metabolites. 1980 Prostaglandins Med pmid:7413850
Cerskus AL et al. Thromboxane B2 and 6-keto-prostaglandin F1 alpha synthesis during infusion of collagen and arachidonic acid in rabbits: inhibition by aspirin and sulfinpyrazone. 1980 Thromb. Res. pmid:7414555
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Davies GC et al. Elevated plasma fibrinopeptide A and thromboxane B2 levels during cardiopulmonary bypass. 1980 Circulation pmid:6965618
Kennedy MS et al. In vitro synthesis of prostaglandins and related lipids by populations of human peripheral blood mononuclear cells. 1980 Prostaglandins pmid:6967616
Galli C et al. Modulation of prostaglandin production in tissues by dietary essential fatty acids. 1980 Acta Med. Scand. Suppl. pmid:6935943
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Rao GH et al. Influence of epinephrine on the aggregation response of aspirin-treated platelets. 1980 Prostaglandins Med pmid:7403340
Schrör K et al. Preservation of ischemic myocardium by pinane thromboxane A2. 1980 Am. J. Physiol. pmid:7356037
Hassid A and Dunn MJ Microsomal prostaglandin biosynthesis of human kidney. 1980 J. Biol. Chem. pmid:7358683
Kadowitz PJ and Hyman AL Comparative effects of thromboxane B2 on the canine and feline pulmonary vascular bed. 1980 J. Pharmacol. Exp. Ther. pmid:7365689
Schlondorff D and Folkert VW Prostaglandin synthesis in glomeruli from rats with unilateral ureteral obstruction. 1980 Adv Prostaglandin Thromboxane Res pmid:7369028
Powell WS Rapid extraction of oxygenated metabolites of arachidonic acid from biological samples using octadecylsilyl silica. 1980 Prostaglandins pmid:6258197
Kent L et al. Differential response of articular chondrocyte populations to thromboxane B2 and analogs of prostaglandin cyclic endoperoxides. 1980 Prostaglandins pmid:7384546
Pace-Asciak CR and Edwards NS Tetranor thromboxane B2 is the principal urinary catabolite formed after i.v. infusion of thromboxane B2 in the rat. 1980 Biochem. Biophys. Res. Commun. pmid:7458943
Viinikka L and Ylikorkala O Measurement of thromboxane B2 in human plasma or serum by radioimmunoassay. 1980 Prostaglandins pmid:7465865
Lagarde M et al. Increase of platelet thromboxane A2 formation and of its plasmatic half-life in diabetes mellitus. 1980 Thromb. Res. pmid:7466751
Kosaki G et al. The mechanism of the inhibitory effect of protease inhibitors on platelet aggregation and cellular synthesis of prostaglandins. I. The effect on the release of arachidonic acid from phospholipids. 1980 Dec 1-15 Thromb. Res. pmid:6785893
Patrono C et al. Low dose aspirin and inhibition of thromboxane B2 production in healthy subjects. 1980 Feb 1-15 Thromb. Res. pmid:7368167
Koh H et al. A radioimmunoassay of thromboxane B2 with thromboxane B2-125I-tyramide and its application to the study on the thromboxane B2 formation during platelet aggregation. 1980 Feb 1-15 Thromb. Res. pmid:7368170
Boyd JA and Eling TE Prostaglandin release and the interaction of platelets with the pulmonary vasculature of rat and guinea pig. 1980 Jul 1-15 Thromb. Res. pmid:7003800
Strand JC et al. Effect of imidazole on renal function in unilateral ureteral-obstructed rat kidneys. 1981 Am. J. Physiol. pmid:6787931
Stuart MJ et al. Abnormal platelet function and arachidonate metabolism in chronic idiopathic thrombocytopenic purpura. 1981 Blood pmid:6788109
Handin RI and Alexander RW Humoral heartache -- do platelets have a role? 1981 N. Engl. J. Med. pmid:7010170
Robertson RM et al. Thromboxane A2 in vasotonic angina pectoris: evidence from direct measurements and inhibitor trials. 1981 N. Engl. J. Med. pmid:7010173
Fasce L et al. [Effects of glucocorticoids on the gastrointestinal tract of normal rats and rats deficient in endogenous prostaglandins]. 1981 Boll. Soc. Ital. Biol. Sper. pmid:7295403
Tada M et al. Elevation of thromboxane B2 levels in patients with classic and variant angina Pectoris. 1981 Circulation pmid:7296786
McManus LM et al. Acetyl glyceryl ether phosphorylcholine. Intravascular alterations following intravenous infusion into the baboon. 1981 Lab. Invest. pmid:7300244
Mehta J and Mehta P Significance of platelet function and thromboxane B2 levels across the human myocardial vascular bed. 1981 Acta Med. Scand. Suppl. pmid:6948499
Capitanio A et al. Platelet abnormalities in renal transplantation. 1981 Proc Eur Dial Transplant Assoc pmid:6460244
Williamson EM et al. Studies on the mechanism of action of 12-deoxyphorbolphenylacetate, a potent platelet aggregating tigliane ester. 1981 Biochem. Pharmacol. pmid:6794576
Ylikorkala O et al. Prostacyclin and thromboxane in diabetes. 1981 Br Med J (Clin Res Ed) pmid:6794795
Feuerstein N and Ramwell PW OKY-1581, a potential selective thromboxane synthetase inhibitor. 1981 Eur. J. Pharmacol. pmid:7195815
Satoh H et al. Influence of angiotensins (I, II & III) on prostaglandin production by minced rat renal medulla. 1981 Prostaglandins pmid:7197382