Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Chong ZZ and Feng YP | Effects of dl-3-n-butylphthalide on production of TXB2 and 6-keto-PGF1 alpha in rat brain during focal cerebral ischemia and reperfusion. | 1997 | Zhongguo Yao Li Xue Bao | pmid:10322905 |
Hanaoka M et al. | Interferon-alpha elevates pulmonary blood pressure in sheep--the role of thromboxane cascade. | 1999 | Eur. J. Pharmacol. | pmid:10323263 |
Heindl B et al. | The volatile anesthetic sevoflurane mitigates cardiodepressive effects of platelets in reperfused hearts. | 1999 | Basic Res. Cardiol. | pmid:10326658 |
Agnoli GC et al. | Renal function and urinary prostanoid excretions in salt-depleted women: comparative effects of enalapril and indomethacin treatments. | 1999 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10328327 |
Chahine R et al. | The anti-thromboxane A2 synthetase activity of myocardial tissue and its variation during ischemia and reperfusion in isolated rabbit heart. | 1999 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10328329 |
Peredo HA and Filinger EJ | Effect of dipyridamole on prostanoid production in rat isolated atria. | 1999 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10328333 |
Denizot Y et al. | Are lipid mediators implicated in the production of pro- and anti-inflammatory cytokines during cardiopulmonary bypass graft with extracorporeal circulation? | 1999 | Cytokine | pmid:10328869 |
Kanji VK et al. | Vitamin E suppresses cyclosporine A-induced increase in the urinary excretion of arachidonic acid metabolites including F2-isoprostanes in the rat model. | 1999 | Transplant. Proc. | pmid:10331052 |
Salomon P and Halawa B | [Levels of neuropeptide Y and thromboxane B2 in patients with variant angina]. | 1998 | Pol. Arch. Med. Wewn. | pmid:10335040 |
Liguori A et al. | Loop diuretics enhance the secretion of prostacyclin in vitro, in healthy persons, and in patients with chronic heart failure. | 1999 | Eur. J. Clin. Pharmacol. | pmid:10335906 |