| MeSH term | MeSH ID | Detail |
|---|---|---|
| Gastritis | D005756 | 27 associated lipids |
| Gastrointestinal Diseases | D005767 | 20 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Glomerulonephritis | D005921 | 35 associated lipids |
| Glomerulonephritis, IGA | D005922 | 7 associated lipids |
| Glomerulosclerosis, Focal Segmental | D005923 | 4 associated lipids |
| Graft Occlusion, Vascular | D006083 | 11 associated lipids |
| Rhinitis, Allergic, Seasonal | D006255 | 7 associated lipids |
| Heart Defects, Congenital | D006330 | 20 associated lipids |
| Heart Failure | D006333 | 36 associated lipids |
Thromboxane b2
Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
Cross Reference
Introduction
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Thromboxane b2?
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Thromboxane b2
PubChem Associated disorders and diseases
What pathways are associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Thromboxane b2?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Thromboxane b2?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
What genes are associated with Thromboxane b2?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Thromboxane b2
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Lazarewicz JW et al. | Effects of MK-801 and ganglioside GM1 on postischemic prostanoid release and hippocampal lesion in gerbil brain. | 1994 | Acta Neurobiol Exp (Wars) | pmid:7887181 |
| Wilkes BM et al. | Reduced thromboxane receptor affinity and vasoconstrictor responses in placentae from diabetic pregnancies. | 1994 | Placenta | pmid:7886025 |
| Baker AJ and Fuller RW | Loss of response to beta-adrenoceptor agonists during the maturation of human monocytes to macrophages in vitro. | 1995 | J. Leukoc. Biol. | pmid:7884310 |
| Nakamura H et al. | Heparin-enhanced plasma phospholipase A2 activity and prostacyclin synthesis in patients undergoing cardiac surgery. | 1995 | J. Clin. Invest. | pmid:7883954 |
| Canale P et al. | Beneficial effects of BAY u3405, a novel thromboxane A2 receptor antagonist, in splanchnic artery occlusion shock. | 1994 | Pharmacology | pmid:7878075 |
| Roumen RM et al. | Inflammatory mediators in relation to the development of multiple organ failure in patients after severe blunt trauma. | 1995 | Crit. Care Med. | pmid:7874897 |
| Hotter G et al. | Nitric oxide and arachidonate metabolism in ischemia-reperfusion associated with pancreas transplantation. | 1995 | Transplantation | pmid:7871573 |
| Diczfalusy U | Beta-oxidation of eicosanoids. | 1994 | Prog. Lipid Res. | pmid:7870740 |
| Fels LM et al. | Early urinary markers of target nephron segments as studied in cadmium toxicity. | 1994 | Kidney Int. Suppl. | pmid:7869678 |
| Charan NB et al. | Streptococcus pneumoniae-induced pulmonary hypertension and systemic hypotension in anesthetized sheep. | 1994 | J. Appl. Physiol. | pmid:7868418 |
| Wang CH et al. | [Clinical and experimental study on effect of Chinese herbal drugs on producing prostaglandin in gastric mucosa]. | 1994 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:7865999 |
| Faure P et al. | Influence of a long-term zinc-deficient diet on rat platelet function and fatty acid composition. | 1995 | Biometals | pmid:7865995 |
| Cardinali DP et al. | The effects of melatonin in human platelets. | 1993 | Acta Physiol Pharmacol Ther Latinoam | pmid:7865868 |
| Cole AT et al. | Low dose aspirin: selective inhibition of rectal dialysis thromboxane B2 in healthy volunteers. | 1994 | Aliment. Pharmacol. Ther. | pmid:7865644 |
| Kilby MD | Neonatal platelet reactivity and serum thromboxane B2 production in whole blood: the effect of maternal low dose aspirin and platelet activation in normotensive and hypertensive pregnancies complicated by intrauterine growth retardation. | 1994 | Br J Obstet Gynaecol | pmid:7864999 |
| Lai LJ et al. | Trilinolein inhibits epinephrine-induced human platelet aggregation. | 1994 | Thromb. Res. | pmid:7863478 |
| Schmitz PG et al. | Acquired essential fatty acid depletion in the remnant kidney: amelioration with U-63557A. | 1994 | Kidney Int. | pmid:7861715 |
| Madan ZM and Sainani GS | Changes in 6 keto PGF1 alpha and TXB2 in patients with myocardial infarction. | 1994 | J Assoc Physicians India | pmid:7860468 |
| Edwards JS and Ritter JM | Effect of cytoplasmic pH on Ca(2+)-stimulated eicosanoid biosynthesis in human platelets. | 1994 | Br. J. Pharmacol. | pmid:7858887 |
| Grassi-Kassisse DM et al. | Modulation by endogenous prostanoids of the vasoconstrictor activity of endothelin-1 in the canine isolated, perfused spleen. | 1994 | Br. J. Pharmacol. | pmid:7858855 |
| Depin JC et al. | Pharmacodynamics and antithrombotic effects after intravenous administration of the new thromboxane A2 receptor antagonist sodium 4-[[1-[[[(4-chlorophenyl)sulfonyl]amino]methyl]cyclopentyl] methyl]benzeneacetate. | 1994 | Arzneimittelforschung | pmid:7848332 |
| Ingram AJ et al. | Effects of flaxseed and flax oil diets in a rat-5/6 renal ablation model. | 1995 | Am. J. Kidney Dis. | pmid:7847360 |
| Andersen PH et al. | Endotoxin and arachidonic acid metabolites in portal, hepatic and arterial blood of cattle with acute ruminal acidosis. | 1994 | Acta Vet. Scand. | pmid:7847191 |
| Rizk M and Abdel-Rahman MS | Salicylamide reverses the aspirin-antagonistic effect of salicylic acid on rat platelet cyclooxygenase. | 1994 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:7846108 |
| Norman JF and Miller CW | Prostacyclin, thromboxane A2, and atherosclerosis in young hypercholesterolemic swine. | 1994 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:7846098 |
| Neuer A et al. | The effect of zearalenone and 17 beta-estradiol on prostacyclin and thromboxane production in cell cultures from human umbilical cord veins. | 1994 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:7846091 |
| Peredo HA et al. | Prostanoid production in hypoxic rat isolated atria: influence of acute diabetes. | 1994 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:7846089 |
| Closa D et al. | Prostanoid generation in early stages of acute pancreatitis: a role for nitric oxide. | 1994 | Inflammation | pmid:7843792 |
| Wang ZG et al. | [Experimental study and clinical application of endothelium seeded vena caval prostheses]. | 1994 | Zhonghua Wai Ke Za Zhi | pmid:7842898 |
| Shao CR et al. | [Clinical and experimental study on Ligusticum wallichii mixture in preventing and treating bronchial asthma]. | 1994 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:7841753 |
| Kubo K et al. | Effects of ONO-5046, a specific neutrophil elastase inhibitor, on endotoxin-induced lung injury in sheep. | 1994 | J. Appl. Physiol. | pmid:7836137 |
| Kurrek MM et al. | Platelet factor 4 injection produces acute pulmonary hypertension in the awake lamb. | 1995 | Anesthesiology | pmid:7832299 |
| Edwards AT et al. | Systemic responses in patients with intermittent claudication after treadmill exercise. | 1994 | Br J Surg | pmid:7827927 |
| Pratico D et al. | Cyclooxygenase-dependent formation of the isoprostane 8-epi prostaglandin F2 alpha. | 1994 | Ann. N. Y. Acad. Sci. | pmid:7825834 |
| Kernacki KA and Berk RS | Characterization of arachidonic acid metabolism and the polymorphonuclear leukocyte response in mice infected intracorneally with Pseudomonas aeruginosa. | 1995 | Invest. Ophthalmol. Vis. Sci. | pmid:7822143 |
| Klockenbusch W et al. | Excretion of prostacyclin and thromboxane metabolites before, during, and after pregnancy-induced hypertension. | 1994 | Eur. J. Obstet. Gynecol. Reprod. Biol. | pmid:7821503 |
| Andrus PK et al. | Effects of the lipid peroxidation inhibitor tirilazad mesylate (U-74006F) on gerbil brain eicosanoid levels following ischemia and reperfusion. | 1994 | Brain Res. | pmid:7820653 |
| Adatia I et al. | Effect of intracardiac repair on biosynthesis of thromboxane A2 and prostacyclin in children with a left to right shunt. | 1994 | Br Heart J | pmid:7818962 |
| Nakano T et al. | Role of pulmonary intravascular macrophages in anti-platelet serum-induced pulmonary hypertension in sheep. | 1994 | Respir Physiol | pmid:7817044 |
| Fauler J et al. | Impaired degradation of prostaglandins and thromboxane in Zellweger syndrome. | 1994 | Pediatr. Res. | pmid:7816519 |
| Kushiku K et al. | Activation of endogenous thromboxane A2 biosynthesis mediates presynaptic inhibition by endothelin-3 of dog stellate ganglionic transmission. | 1995 | J. Pharmacol. Exp. Ther. | pmid:7815366 |
| Orlandi M et al. | Thromboxane A2 synthase activity in platelet free human monocytes. | 1994 | Biochim. Biophys. Acta | pmid:7811713 |
| Kauser K and Rubanyi GM | Gender difference in bioassayable endothelium-derived nitric oxide from isolated rat aortae. | 1994 | Am. J. Physiol. | pmid:7810731 |
| Hollenberg SM et al. | Eicosanoid production by human aortic endothelial cells in response to endothelin. | 1994 | Am. J. Physiol. | pmid:7810729 |
| Lane NJ et al. | Inhibition of leukotriene B4 synthesis does not prevent development of acute renal failure following storage and transplantation. | 1994 | Transplantation | pmid:7809921 |
| Goulet JL et al. | Altered inflammatory responses in leukotriene-deficient mice. | 1994 | Proc. Natl. Acad. Sci. U.S.A. | pmid:7809134 |
| Meng XJ and Wang JL | Arachidonic acid metabolism in galactosamine/endotoxin induced acute liver injury in rats. | 1994 | J. Tongji Med. Univ. | pmid:7807604 |
| Gibson RL et al. | Group B streptococci (GBS) injure lung endothelium in vitro: GBS invasion and GBS-induced eicosanoid production is greater with microvascular than with pulmonary artery cells. | 1995 | Infect. Immun. | pmid:7806366 |
| Faili A et al. | Dissociation between the phospholipases C and A2 activities in stimulated platelets and their involvement in the arachidonic acid liberation. | 1994 | Br. J. Haematol. | pmid:7803237 |
| Cartwright IJ et al. | A haemorrhagic platelet disorder associated with altered stimulus-response coupling and abnormal membrane phospholipid composition. | 1994 | Br. J. Haematol. | pmid:7803235 |
| Siler-Khodr TM et al. | Dose-related effect of IGF-I on placental prostanoid release. | 1995 | Prostaglandins | pmid:7792387 |
| Guh JH et al. | Antiplatelet effect of gingerol isolated from Zingiber officinale. | 1995 | J. Pharm. Pharmacol. | pmid:7791032 |
| Wu JF and Liu TP | [Effects of berberine on platelet aggregation and plasma levels of TXB2 and 6-keto-PGF1 alpha in rats with reversible middle cerebral artery occlusion]. | 1995 | Yao Xue Xue Bao | pmid:7785438 |
| Salvati P et al. | Long-term thromboxane-synthase inhibition prolongs survival in murine lupus nephritis. | 1995 | Kidney Int. | pmid:7783415 |
| Kotamäki M | Smoking induced differences in autonomic responses in military pilot candidates. | 1995 | Clin. Auton. Res. | pmid:7780288 |
| Iwata M | Pathophysiology of dogs after 84% hepatectomy with emphasis on prostaglandin metabolites and the effect of a thromboxane A2 synthesis inhibitor and a prostaglandin I2 analog. | 1994 | Surg. Today | pmid:7780227 |
| Kawamura M et al. | Evaluation of plasma 11-dehydro-thromboxane B2 as an indicator for thromboxane A2 synthesis in vivo in laboratory animals. | 1995 | Thromb. Res. | pmid:7778061 |
| Anfossi G et al. | Studies on in vitro effect of picotamide on human platelet aggregation in platelet-rich plasma and whole blood. | 1995 | Thromb. Res. | pmid:7778055 |
| VanderMeer TJ et al. | Protective effects of a novel 32-amino acid C-terminal fragment of CAP18 in endotoxemic pigs. | 1995 | Surgery | pmid:7778029 |
| Verheij M et al. | Amelioration of radiation nephropathy by acetylsalicylic acid. | 1995 | Int. J. Radiat. Biol. | pmid:7775834 |
| Walsh SW and Wang Y | Trophoblast and placental villous core production of lipid peroxides, thromboxane, and prostacyclin in preeclampsia. | 1995 | J. Clin. Endocrinol. Metab. | pmid:7775637 |
| VanderMeer TJ et al. | Acute lung injury in endotoxemic pigs: role of leukotriene B4. | 1995 | J. Appl. Physiol. | pmid:7775306 |
| Ichihara T et al. | The effects of using a leukocyte removal filter during cold blood cardioplegia. | 1994 | Surg. Today | pmid:7772907 |
| Menys VC et al. | Spontaneous platelet aggregation in whole blood is increased in non-insulin-dependent diabetes mellitus and in female but not male patients with primary dyslipidemia. | 1995 | Atherosclerosis | pmid:7772062 |
| Schönberger JP et al. | Systemic blood activation with open and closed venous reservoirs. | 1995 | Ann. Thorac. Surg. | pmid:7771838 |
| Rauramo I et al. | Prostacyclin and thromboxane in pregnant and nonpregnant women in response to exercise. | 1995 | Obstet Gynecol | pmid:7770249 |
| Sinzinger H et al. | Arterial wall rather than platelets is responsible for diminished thrombogenicity during isradipine therapy. | 1995 | J. Cardiovasc. Pharmacol. | pmid:7769812 |
| Dodam JR and Olson NC | Effect of fluoride on cardiopulmonary function and release of eicosanoids in pigs. | 1995 | J. Appl. Physiol. | pmid:7759426 |
| Nosál R et al. | [The effect of antihistamines on stimulated blood platelet functions]. | 1995 | Cesk Fysiol | pmid:7758143 |
| Okano S et al. | Effect of platelet activating factor antagonist (CV-3988) on 6-keto-PGF1 alpha and thromboxane B2 in dogs with experimental endotoxin-induced shock. | 1995 | J. Vet. Med. Sci. | pmid:7756431 |
| Prisco D et al. | Effect of n-3 fatty acid ethyl ester supplementation on fatty acid composition of the single platelet phospholipids and on platelet functions. | 1995 | Metab. Clin. Exp. | pmid:7752902 |
| Arribas-Gómez I et al. | A possible role for platelet-activating factor in the hydrogen peroxide-induced TXB2 and PGE2 glomerular synthesis. | 1995 | J. Lipid Res. | pmid:7751813 |
| Schlit AF et al. | Large increase in plasmatic 11-dehydro-TxB2 levels due to oral contraceptives. | 1995 | Contraception | pmid:7750285 |
| Chen WP et al. | In vitro effects of interleukins on human mesangial cells: implications for glomerulonephritis. | 1995 | J. Pathol. | pmid:7745500 |
| Wollert PS et al. | Prior exposure to endotoxin exacerbates lipopolysaccharide-induced hypoxemia and alveolitis in anesthetized swine. | 1994 | Shock | pmid:7743363 |
| Chen H et al. | Endotoxin tolerance: effects on lethality and macrophage thromboxane (B2) and interleukin 6 production. | 1994 | Shock | pmid:7743340 |
| Thunus L et al. | Anti-inflammatory properties of copper, gold and silver, individually and as mixtures. | 1995 | Analyst | pmid:7741265 |
| Ding YA et al. | Antiplatelet actions of 2-(4-[1-(2-chlorophenyl) piperazinyl]) methyl-2,3-dihydroimidazo[1,2-c]quinazolin-5(6H)-one compound. | 1995 | Thromb. Res. | pmid:7740521 |
| Landolfi R et al. | Effects of unfractionated and low molecular weight heparins on platelet thromboxane biosynthesis "in vivo". | 1994 | Thromb. Haemost. | pmid:7740468 |
| Mertz-Nielsen A et al. | Misoprostol inhibits gastric mucosal release of endogenous prostaglandin E2 and thromboxane B2 in healthy volunteers. | 1995 | Gut | pmid:7737555 |
| Noda H et al. | Left ventricular dysfunction and acute lung injury induced by continuous administration of endotoxin in sheep. | 1994 | Shock | pmid:7735964 |
| Kohout M et al. | Cool perfusion solutions for skin flaps: a new mixture of pharmacological agents which improves skin flap viability. | 1995 | Br J Plast Surg | pmid:7735675 |
| Foegh ML et al. | Urinary thromboxane has diagnostic value in myocardial infarction. | 1995 | Adv. Prostaglandin Thromboxane Leukot. Res. | pmid:7732879 |
| Patrignani P et al. | Characterization of the cyclooxygenase activity of human blood prostaglandin endoperoxide synthases. | 1995 | Adv. Prostaglandin Thromboxane Leukot. Res. | pmid:7732817 |
| Balkhy HH et al. | Comparison of Eurocollins and University of Wisconsin solution in single flush preservation of the ischemic reperfused lung: an in vivo rabbit model. | 1995 | Transplantation | pmid:7732552 |
| Pratico D et al. | Cyclooxygenase-dependent formation of the isoprostane, 8-epi prostaglandin F2 alpha. | 1995 | J. Biol. Chem. | pmid:7730359 |
| Billings PC et al. | Effect of modifiers of arachidonic acid metabolism on radiation transformation and eicosanoid formation in C3H/10T1/2 cells. | 1994 | Cancer Biochem. Biophys. | pmid:7728742 |
| Li JX et al. | Effects of cholinergic blockade on hemodynamic disturbances and intestinal lesions in endotoxic shock in newborn piglets. | 1994 | Shock | pmid:7728588 |
| de Clerck F et al. | Inhibition of 5-hydroxytryptamine-induced and -amplified human platelet aggregation by ketanserin (R 41,468), a selective 5-HT2-receptor antagonist. 1982. | 1994 | Agents Actions | pmid:7725978 |
| McGill DA and Ardlie NG | Abnormal platelet reactivity in men with premature coronary heart disease. | 1994 | Coron. Artery Dis. | pmid:7719521 |
| Kalaitzis H et al. | Role of contralateral kidney in the maintenance of two-kidney, one-clip renovascular hypertension. | 1994 | Investig Urol (Berl) | pmid:7719289 |
| Wang XM et al. | [Study on advanced non-small cell lung cancer patients with Qi deficiency and blood stasis syndrome]. | 1994 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:7719106 |
| Song WD et al. | [Relationship between local effect of cortisol used by chronic bronchitis patients and syndrome differentiation in TCM]. | 1994 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:7719090 |
| Valeri CR et al. | Effects of temperature on bleeding time and clotting time in normal male and female volunteers. | 1995 | Crit. Care Med. | pmid:7712760 |
| Proppe DG et al. | Diagnostic value of urinary thromboxane B2 concentration in detection of initial acute rejection reactions in human renal allografts. | 1995 | Transplantation | pmid:7709445 |
| Yashiro M et al. | Amelioration of hypercholesterolaemia by HMG-CoA reductase inhibitor (Pravastatin) improved platelet hyperaggregability in nephrotic patients. | 1994 | Nephrol. Dial. Transplant. | pmid:7708285 |
| McKellar QA et al. | Stereospecific pharmacodynamics and pharmacokinetics of carprofen in the dog. | 1994 | J. Vet. Pharmacol. Ther. | pmid:7707490 |
| Kramer HJ et al. | Impaired renal function in obstructive jaundice: enhanced glomerular thromboxane synthesis and effects of thromboxane receptor blockade in bile duct-ligated rats. | 1995 | Clin. Sci. | pmid:7704998 |
| Baker AJ et al. | Inhibitory actions of salmeterol on human airway macrophages and blood monocytes. | 1994 | Eur. J. Pharmacol. | pmid:7698169 |
| Turi S et al. | The effect of erythropoietin on platelet function in uraemic children on haemodialysis. | 1994 | Pediatr. Nephrol. | pmid:7696114 |