| MeSH term | MeSH ID | Detail |
|---|---|---|
| Gastritis | D005756 | 27 associated lipids |
| Gastrointestinal Diseases | D005767 | 20 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Glomerulonephritis | D005921 | 35 associated lipids |
| Glomerulonephritis, IGA | D005922 | 7 associated lipids |
| Glomerulosclerosis, Focal Segmental | D005923 | 4 associated lipids |
| Graft Occlusion, Vascular | D006083 | 11 associated lipids |
| Rhinitis, Allergic, Seasonal | D006255 | 7 associated lipids |
| Heart Defects, Congenital | D006330 | 20 associated lipids |
| Heart Failure | D006333 | 36 associated lipids |
Thromboxane b2
Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
Cross Reference
Introduction
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Thromboxane b2?
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Thromboxane b2
PubChem Associated disorders and diseases
What pathways are associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Thromboxane b2?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Thromboxane b2?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
What genes are associated with Thromboxane b2?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Thromboxane b2
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Zhou W et al. | Lipid mediator production in acute and chronic pancreatitis in the rat. | 1994 | J. Surg. Res. | pmid:8277767 |
| Smith SR et al. | Chronic thromboxane synthase inhibition with CGS 12970 in human cyclosporine nephrotoxicity. | 1993 | Transplantation | pmid:8279014 |
| Johnson BF et al. | Thromboxane and prostacyclin synthesis in experimental pancreas transplantation. Changes in parenchymal and vascular prostanoids. | 1993 | Transplantation | pmid:8279018 |
| Mück AO et al. | The effect of 17 beta-estradiol and endothelin 1 on prostacyclin and thromboxane production in human endothelial cell cultures. | 1993 | Clin Exp Obstet Gynecol | pmid:8281701 |
| Li Q et al. | Suppression of S-antigen-induced experimental autoimmune uveoretinitis in Lewis rats by oral administration with CGS-13080, a thromboxane synthetase inhibitor. | 1993 | Exp. Eye Res. | pmid:8282047 |
| Szczapa J et al. | [Effect of intraventricular hemorrhage in newborns on levels of certain prostanoids in blood plasma]. | 1993 | Ginekol. Pol. | pmid:8282238 |
| Textor SC et al. | Systemic and renal effects of nifedipine in cyclosporine-associated hypertension. | 1994 | Hypertension | pmid:8282363 |
| Iioka H et al. | Studies on placental inhibition of platelet aggregation: a comparison of human syncytiotrophoblast brush border and basal plasma membranes. | 1993 Sep-Oct | Placenta | pmid:8290492 |
| Semrad SD et al. | Effects of concurrent administration of phenylbutazone and flunixin meglumine on pharmacokinetic variables and in vitro generation of thromboxane B2 in mares. | 1993 | Am. J. Vet. Res. | pmid:8291770 |
| Semrad SD et al. | Pharmacokinetics and effects of repeated administration of phenylbutazone in neonatal calves. | 1993 | Am. J. Vet. Res. | pmid:8291771 |
| Rabinovici R et al. | Interleukin-2-induced lung injury. The role of complement. | 1994 | Circ. Res. | pmid:8293571 |
| Furuzono T et al. | A novel biomaterial: poly(dimethylsiloxane)-polyamide multiblock copolymer I. Synthesis and evaluation of blood compatibility. | 1993 | J Biomater Sci Polym Ed | pmid:8297834 |
| Salerno F et al. | Effects of imidazole-salicylate on renal function and the diuretic action of furosemide in cirrhotic patients with ascites. | 1993 | J. Hepatol. | pmid:8301062 |
| Hofmann D et al. | Evidence for sustained platelet activation in patients with early postinfarction angina. | 1993 | Thromb. Res. | pmid:8303651 |
| van Kooten F et al. | Evidence for episodic platelet activation in acute ischemic stroke. | 1994 | Stroke | pmid:8303731 |
| Nukina S et al. | Glycogenolytic effect of adenosine involves ATP from hepatocytes and eicosanoids from Kupffer cells. | 1994 | Am. J. Physiol. | pmid:8304463 |
| Smith SR et al. | Effect of low-dose aspirin on thromboxane production and the antihypertensive effect of captopril. | 1993 | J. Am. Soc. Nephrol. | pmid:8305640 |
| Schuster DP et al. | Thromboxane receptor stimulation/inhibition and perfusion redistribution after acute lung injury. | 1993 | J. Appl. Physiol. | pmid:8307861 |
| Foegh ML et al. | Urinary thromboxane A2 metabolites in patients presenting in the emergency room with acute chest pain. | 1994 | J. Intern. Med. | pmid:8308478 |
| Suckfüll MM et al. | The contribution of endothelial cells to hyperacute rejection in xenogeneic perfused working hearts. | 1994 | Transplantation | pmid:8310518 |
| Bashakin NF et al. | [The functional characteristics of the prostacyclin-thromboxane system in newborn infants with a history of acute and chronic intrauterine hypoxia]. | 1993 | Akush Ginekol (Mosk) | pmid:8311150 |
| Edwin SS et al. | Cyclosporin A attenuates increased prostaglandin and thromboxane production in response to various stimuli in human decidua. | 1993 Sep-Oct | Am. J. Reprod. Immunol. | pmid:8311924 |
| Wang XP et al. | [Therapeutic effects and mechanisms of tetramethylpyrazine on lung injury in acute haemorrhagic necrotizing pancreatitis in rats]. | 1993 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:8312699 |
| Napolov IuK et al. | [The effect of x-ray contrast media on the amount of thromboxane and prostacyclin in the blood of man and rats in vivo and in vitro]. | 1993 Sep-Oct | Eksp Klin Farmakol | pmid:8312809 |
| Huang YS | [Thromboxane and prostacyclin imbalance in the pathogenesis of early damage after severe burns]. | 1993 | Zhonghua Yi Xue Za Zhi | pmid:8313186 |
| Yuan W | [Changes in renal cortical thromboxane A2, prostaglandin F1 alpha and effects of dazoxiben, chuan xiong on in situ immune complex glomerulonephritis in rats]. | 1993 | Zhonghua Yi Xue Za Zhi | pmid:8313194 |
| Randomized trial of ridogrel, a combined thromboxane A2 synthase inhibitor and thromboxane A2/prostaglandin endoperoxide receptor antagonist, versus aspirin as adjunct to thrombolysis in patients with acute myocardial infarction. The Ridogrel Versus Aspirin Patency Trial (RAPT). | 1994 | Circulation | pmid:8313547 | |
| Schumacher WA et al. | Comparison of a thromboxane receptor antagonist and aspirin in experimental arterial thrombosis. | 1993 Jul-Aug | Haemostasis | pmid:8314172 |
| Hudson N et al. | Effect of Helicobacter pylori colonisation on gastric mucosal eicosanoid synthesis in patients taking non-steroidal anti-inflammatory drugs. | 1993 | Gut | pmid:8314505 |
| Romero R et al. | The relationship between spontaneous rupture of membranes, labor, and microbial invasion of the amniotic cavity and amniotic fluid concentrations of prostaglandins and thromboxane B2 in term pregnancy. | 1993 | Am. J. Obstet. Gynecol. | pmid:8317506 |
| Li JX et al. | Capsular type-specific polysaccharide partially inhibits group B Streptococcus-induced pulmonary hypertension. | 1993 | Am. Rev. Respir. Dis. | pmid:8317791 |
| Swaim SF et al. | The greyhound dog as a model for studying pressure ulcers. | 1993 | Decubitus | pmid:8318156 |
| Olson RW et al. | Beneficial effects of combined thromboxane synthase inhibition/receptor blockade with CGS 22652 in a canine model of coronary thrombosis. | 1993 | Eur. J. Pharmacol. | pmid:8319746 |
| van Pampus EC et al. | Influence of aspirin on human megakaryocyte prostaglandin synthesis. | 1993 | Eur. J. Haematol. | pmid:8319788 |
| Peredo HA and Enero MA | Effect of endothelium removal on basal and muscarinic cholinergic stimulated rat mesenteric vascular bed prostanoid synthesis. | 1993 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:8321873 |
| Chiabrando C et al. | Urinary excretion and origin of 11-dehydro-2,3-dinor-thromboxane B2 in man. | 1993 | Prostaglandins | pmid:8321910 |
| Ohara N et al. | Tissue eicosanoids and vascular permeability in rats with chronic biliary obstruction. | 1993 | Hepatology | pmid:8325602 |
| Lemne C et al. | Plasma growth factor activity and cardiac wall thickness. | 1993 | J. Intern. Med. | pmid:8326295 |
| Patterson WR et al. | Aggregation of killer whale platelets. | 1993 | Thromb. Res. | pmid:8327987 |
| Weiss HJ and Lages B | Studies of thromboxane B2, platelet factor 4, and fibrinopeptide A in bleeding-time blood of patients deficient in von Willebrand factor, platelet glycoproteins Ib and IIb-IIIa, and storage granules. | 1993 | Blood | pmid:8329704 |
| Rouse DJ et al. | Midpregnancy serum thromboxane B2 determinations do not predict subsequent adverse pregnancy outcomes. | 1993 | Am. J. Obstet. Gynecol. | pmid:8333431 |
| Kraayenbrink AA et al. | Endothelial vasoactive mediators in preeclampsia. | 1993 | Am. J. Obstet. Gynecol. | pmid:8333445 |
| Vollmar B et al. | Heparin-protamine reactions in pigs: role of oxygen-derived free radicals. | 1993 | J. Appl. Physiol. | pmid:8335575 |
| Mahmoud TZ et al. | Correlation between umbilical artery resistance index, 6 ketoprostaglandin F1 alpha and thromboxane B2 in the fetoplacental compartment in patients with pregnancy induced hypertension. | 1993 | Prostaglandins | pmid:8337411 |
| Myers SI et al. | Burn injury decreased splanchnic PGI2 release is restored by treatment with lazaroid. | 1993 | Prostaglandins | pmid:8337413 |
| Keith JC et al. | Effects of ridogrel on the prostacyclin-thromboxane ratio in nulliparous third trimester-pregnant rhesus monkeys. | 1993 | Prostaglandins | pmid:8337414 |
| Wetzka B et al. | Eicosanoid production by intrauterine tissues before and after labor in short-term tissue culture. | 1993 | Prostaglandins | pmid:8337416 |
| Gu YJ et al. | Biocompatibility of leukocyte removal filters during leukocyte filtration of cardiopulmonary bypass perfusate. | 1993 | Artif Organs | pmid:8338443 |
| Ford I et al. | Mechanisms of platelet aggregation by Streptococcus sanguis, a causative organism in infective endocarditis. | 1993 | Br. J. Haematol. | pmid:8338784 |
| Wang SR et al. | [Experimental study on effects of 18 kinds of Chinese herbal medicine for synthesis of thromboxane A2 and PGI2]. | 1993 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:8339039 |
| Keimowitz RM et al. | Transdermal modification of platelet function. A dermal aspirin preparation selectively inhibits platelet cyclooxygenase and preserves prostacyclin biosynthesis. | 1993 | Circulation | pmid:8339418 |
| Tesson F et al. | Cell-associated and soluble phospholipases A2 increase during carrageenan and zymosan-induced pleurisy in rat. | 1993 | Eur. J. Pharmacol. | pmid:8339752 |
| Loick HM et al. | Thromboxane receptor blockade with BM 13,177 following toxic airway damage by smoke inhalation in sheep. | 1993 | Eur. J. Pharmacol. | pmid:8339755 |
| Ritter JM et al. | Thromboxane A2 receptor antagonism and synthase inhibition in essential hypertension. | 1993 | Hypertension | pmid:8340155 |
| Beitz A et al. | Lipoproteins from normolipidemic and dyslipidemic subjects modify the thromboxane A2 generation by platelets in clotting human blood. | 1993 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:8341726 |
| Vissinger H et al. | Platelet-derived growth factor release and antiplatelet treatment with low-dose acetylsalicylic acid. | 1993 | Angiology | pmid:8342880 |
| Horgan PG et al. | Extracorporeal shock wave lithotripsy induces the release of prostaglandins which increase ureteric peristalsis. | 1993 | Br J Urol | pmid:8343888 |
| Qu J and Thomas K | Prostaglandins stimulate the secretion of inhibin from human placental cells. | 1993 | J. Clin. Endocrinol. Metab. | pmid:8345062 |
| Capaz FR et al. | Effect of active sensitization on the bronchopulmonary responses to tachykinins in the guinea pig. Modulation by peptidase inhibitors. | 1993 | J. Pharmacol. Exp. Ther. | pmid:8355211 |
| Aziz SM et al. | Intrinsic microbicidal activity and pulmonary hypertension in isolated newborn piglet lungs. | 1993 | Pediatr. Res. | pmid:8356015 |
| Chu ZM and Beilin LJ | Mechanisms of vasodilatation in pregnancy: studies of the role of prostaglandins and nitric-oxide in changes of vascular reactivity in the in situ blood perfused mesentery of pregnant rats. | 1993 | Br. J. Pharmacol. | pmid:8358537 |
| Sumiya T et al. | Effects of reactive oxygen species on arachidonic acid metabolism in rabbit platelets. | 1993 | Free Radic. Biol. Med. | pmid:8359708 |
| Gow JA et al. | The effect of regular and enteric-coated aspirin on bleeding time, thromboxane, and prostacyclin. | 1993 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:8361987 |
| Mounier C et al. | Secretory phospholipase A2 is not required for arachidonic acid liberation during platelet activation. | 1993 | Eur. J. Biochem. | pmid:8365403 |
| de la Cruz JP et al. | Antiplatelet effect of pentoxifylline in human whole blood. | 1993 | Gen. Pharmacol. | pmid:8365640 |
| Takasaki W et al. | Superiority of plasma 11-dehydro-TXB2 to TXB2 as an index of in vivo TX formation in rabbits after dosing of CS-518, a TX synthase inhibitor. | 1993 | Thromb. Res. | pmid:8367836 |
| Diczfalusy U et al. | Peroxisomal chain-shortening of thromboxane B2: evidence for impaired degradation of thromboxane B2 in Zellweger syndrome. | 1993 | J. Lipid Res. | pmid:8371058 |
| Semrad SD et al. | Effect of tirilazad mesylate (U74006F) on eicosanoid and tumor necrosis factor generation in healthy and endotoxemic neonatal calves. | 1993 | Circ. Shock | pmid:8375024 |
| Chen TY et al. | Protective effects of E5, an antiendotoxin monoclonal antibody, in the ovine pulmonary circulation. | 1993 | J. Appl. Physiol. | pmid:8376269 |
| Sullivan MH et al. | Effects of a thromboxane synthetase inhibitor on platelet function; possible risks of use in pregnancy. | 1993 | Prostaglandins | pmid:8378539 |
| Klimm JL et al. | Effects of free and macromolecular-bound TXA2 receptor antagonist BM 13.505 on U46619-induced platelet aggregation. | 1993 | Prostaglandins | pmid:8378540 |
| Ko FN et al. | CIS-19, a novel platelet activating factor receptor antagonist: in vitro and in vivo studies. | 1993 | Biochim. Biophys. Acta | pmid:8380343 |
| Slama H et al. | Metabolism of arachidonic acid by caruncular and allantochorionic tissues in cows with retained fetal membranes (RFM). | 1993 | Prostaglandins | pmid:8380936 |
| Arora RR et al. | Laser-induced stimulation of thromboxane B2 synthesis in human blood platelets: role of superoxide radicals. | 1993 | Am. Heart J. | pmid:8381256 |
| Jones SA et al. | Eicosanoids in third ventricular cerebrospinal fluid of fetal and newborn sheep. | 1993 | Am. J. Physiol. | pmid:8381613 |
| Su M et al. | Lung mast cells increase in number and degranulate during pulmonary artery occlusion/reperfusion injury in dogs. | 1993 | Am. Rev. Respir. Dis. | pmid:8381632 |
| Nanji AA et al. | Severity of liver injury in experimental alcoholic liver disease. Correlation with plasma endotoxin, prostaglandin E2, leukotriene B4, and thromboxane B2. | 1993 | Am. J. Pathol. | pmid:8382006 |
| Santana AC et al. | Anti-inflammatory activities of Ph CL28A in rats in vivo. | 1993 | Eur. J. Pharmacol. | pmid:8384113 |
| Bruner G and Murphy S | Purinergic P2Y receptors on astrocytes are directly coupled to phospholipase A2. | 1993 | Glia | pmid:8384160 |
| Smith MA et al. | Changes in inflammatory mediators in experimental periodontitis in the rhesus monkey. | 1993 | Infect. Immun. | pmid:8384162 |
| Kuratomi Y et al. | Effect of a 5-lipoxygenase inhibitor on endotoxin-induced pulmonary dysfunction in awake sheep. | 1993 | J. Appl. Physiol. | pmid:8384614 |
| Gyenes M and De Groot H | Prostanoid release by Kupffer cells upon hypoxia-reoxygenation: role of pHi and Cai2+. | 1993 | Am. J. Physiol. | pmid:8384798 |
| Noronha-Blob L et al. | NPC 15669, an inhibitor of neutrophil recruitment, is efficacious in acetic acid-induced colitis in rats. | 1993 | Gastroenterology | pmid:8385041 |
| Giembycz MA et al. | Leukotriene D4 receptors are not negatively coupled to adenylyl cyclase in guinea-pig lung parenchyma. | 1993 | Br. J. Pharmacol. | pmid:8385538 |
| Carrick JB et al. | Administration of a receptor antagonist for platelet-activating factor during equine endotoxaemia. | 1993 | Equine Vet. J. | pmid:8385601 |
| Croft KD and Beilin LJ | Platelet and neutrophil function and eicosanoid release in a subject with abetalipoproteinaemia. | 1993 | Thromb. Res. | pmid:8385810 |
| Oishi K and Yamaguchi M | Regulatory effect of arachidonic acid on the calcium transport system in rat liver nuclei. | 1993 | Biochem. Pharmacol. | pmid:8385946 |
| Villanueva M et al. | Equipotent inhibition by R(-)-, S(+)- and racemic ibuprofen of human polymorphonuclear cell function in vitro. | 1993 | Br J Clin Pharmacol | pmid:8385973 |
| Boeynaems JM et al. | Enhancement of the endothelial production of prostacyclin by substituted derivatives of BAPTA-AM. | 1993 | Eur. J. Pharmacol. | pmid:8386085 |
| Kruse-Elliott KT and Olson NC | CGS 8515 and indomethacin attenuate cytokine-induced cardiopulmonary dysfunction in pigs. | 1993 | Am. J. Physiol. | pmid:8386479 |
| Closa D et al. | Cyclooxygenase and lipoxygenase metabolism in sodium taurocholate induced acute hemorrhagic pancreatitis in rats. | 1993 | Prostaglandins | pmid:8388115 |
| Faili A et al. | Reduction by arachidonic acid of prostaglandin I2-induced cyclic AMP formation. Involvement of prostaglandins E2 and F2 alpha. | 1993 | Biochem. Pharmacol. | pmid:8388209 |
| Farina PR et al. | A prodrug of a 2,6-disubstituted 4-(2-arylethenyl)phenol is a selective and orally active 5-lipoxygenase inhibitor. | 1993 | J. Pharmacol. Exp. Ther. | pmid:8388452 |
| Wiles ME et al. | Hypoxia reoxygenation-induced injury of cultured pulmonary microvessel endothelial cells. | 1993 | J. Leukoc. Biol. | pmid:8388909 |
| Brightling CE et al. | Isoprenaline inhibits thromboxane B2 release from U937 cells. | 1993 | J. Leukoc. Biol. | pmid:8388911 |
| Llopis J et al. | Eicosanoids released following inhibition of the endoplasmic reticulum Ca2+ pump stimulate Ca2+ efflux in the perfused rat liver. | 1993 | Biochem. Pharmacol. | pmid:8390834 |
| Paterson IS et al. | Reperfusion plasma contains a neutrophil activator. | 1993 | Ann Vasc Surg | pmid:8390848 |
| Chou TZ et al. | Effect of felodipine-ER on blood pressure, platelet function, and rheological properties in hypertension. | 1993 | Can J Cardiol | pmid:8394193 |
| Wang ZY et al. | Differential effects of new breviscapine on arachidonic acid metabolisms in blood cells and endothelial cells. | 1993 | Zhongguo Yao Li Xue Bao | pmid:8394637 |
| Wang ZY et al. | Effect of leukotriene B4 on arachidonate metabolism and activation of blood cells and endothelial cells. | 1993 | Zhongguo Yao Li Xue Bao | pmid:8394638 |