Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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There are no associated biomedical information in the current reference collection.
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Wang W et al. | Effects of magnesium lithospermate B on aggregation and 5-HT release in rabbit washed platelets. | 2000 | Acta Pharmacol. Sin. | pmid:11501172 |
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Wang LL et al. | Effects of MN-9202 on platelet aggregation, 5-HT release, TXB2 synthesis, and calcium mobilization in rabbit platelets in vitro. | 2000 | Acta Pharmacol. Sin. | pmid:11360670 |
Peng LL et al. | Associations of MDR1, TBXA2R, PLA2G7, and PEAR1 genetic polymorphisms with the platelet activity in Chinese ischemic stroke patients receiving aspirin therapy. | 2016 | Acta Pharmacol. Sin. | pmid:27641736 |
Kapui Z et al. | The mechanism of cytoprotective effect of CHINOIN-127. | 1992 | Acta Physiol Hung | pmid:1345193 |
Nagy S et al. | A canine model of hyperdynamic sepsis induced by intestinal ischemia. | 1990 | Acta Physiol Hung | pmid:2075825 |
Nádasy GL et al. | Role of endothelium, oxygen and ionic milieu in the prostacyclin and thromboxane production of rat aortic tissue slices. | 1991 | Acta Physiol Hung | pmid:1763652 |
Somova L et al. | Pathogenesis of cardiovascular disorders in streptozotocin-induced diabetes in rat. II. Correlation between lipid peroxides, thromboxane A2/prostacyclin, and platelet aggregation in different stages of diabetes. | 1988 | Acta Physiol Pharmacol Bulg | pmid:3066112 |