| MeSH term | MeSH ID | Detail |
|---|---|---|
| Enteritis | D004751 | 8 associated lipids |
| Fetal Diseases | D005315 | 8 associated lipids |
| Salmonella Infections, Animal | D012481 | 9 associated lipids |
| Hypertension, Renal | D006977 | 9 associated lipids |
| Coronary Vasospasm | D003329 | 9 associated lipids |
| Magnesium Deficiency | D008275 | 9 associated lipids |
| Leukopenia | D007970 | 9 associated lipids |
| Tooth, Impacted | D014095 | 9 associated lipids |
| Thrombocythemia, Essential | D013920 | 9 associated lipids |
| Carbon Monoxide Poisoning | D002249 | 9 associated lipids |
Thromboxane b2
Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
Cross Reference
Introduction
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Thromboxane b2?
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Thromboxane b2
PubChem Associated disorders and diseases
What pathways are associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Thromboxane b2?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Thromboxane b2?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
What genes are associated with Thromboxane b2?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Thromboxane b2
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Badesch DB et al. | Decreased arterial wall prostaglandin production in neonatal calves with severe chronic pulmonary hypertension. | 1989 | Am. J. Respir. Cell Mol. Biol. | pmid:2517777 |
| Shellito J and Sniezek M | Altered release of eicosanoids by rat alveolar macrophages during granulomatous pulmonary inflammation. | 1990 | Am. J. Respir. Cell Mol. Biol. | pmid:2155633 |
| Sayers BC et al. | Role of cyclooxygenase-2 in exacerbation of allergen-induced airway remodeling by multiwalled carbon nanotubes. | 2013 | Am. J. Respir. Cell Mol. Biol. | pmid:23642096 |
| Ciabattoni G et al. | In vivo lipid peroxidation and platelet activation in cystic fibrosis. | 2000 | Am. J. Respir. Crit. Care Med. | pmid:11029317 |
| Mitra A et al. | Thromboxane-mediated alveolar responses to acute obstruction of the pulmonary vasculature. | 1997 | Am. J. Respir. Crit. Care Med. | pmid:9117035 |
| Vass G et al. | Comparison of nasal and oral inhalation during exhaled breath condensate collection. | 2003 | Am. J. Respir. Crit. Care Med. | pmid:12493648 |
| Okazawa A et al. | 8-Epi-PGF2alpha induces airflow obstruction and airway plasma exudation in vivo. | 1997 | Am. J. Respir. Crit. Care Med. | pmid:9032175 |
| Pavord ID et al. | Induced sputum eicosanoid concentrations in asthma. | 1999 | Am. J. Respir. Crit. Care Med. | pmid:10588604 |
| Kataoka M et al. | A long-acting prostacyclin agonist with thromboxane inhibitory activity for pulmonary hypertension. | 2005 | Am. J. Respir. Crit. Care Med. | pmid:16192456 |
| Snapper JR et al. | Role of endothelin in endotoxin-induced sustained pulmonary hypertension in sheep. | 1998 | Am. J. Respir. Crit. Care Med. | pmid:9445282 |
| Chen CR et al. | Platelet-activating factor potentiates protamine-induced lung edema. Role of eicosanoids. | 1994 | Am. J. Respir. Crit. Care Med. | pmid:8111595 |
| Jankov RP et al. | Thromboxane A(2) receptors mediate pulmonary hypertension in 60% oxygen-exposed newborn rats by a cyclooxygenase-independent mechanism. | 2002 | Am. J. Respir. Crit. Care Med. | pmid:12119234 |
| Gust R et al. | Role of cyclooxygenase-2 in oleic acid-induced acute lung injury. | 1999 | Am. J. Respir. Crit. Care Med. | pmid:10508803 |
| Mayer K et al. | Acute lung injury is reduced in fat-1 mice endogenously synthesizing n-3 fatty acids. | 2009 | Am. J. Respir. Crit. Care Med. | pmid:19136374 |
| Gust R et al. | Synergistic hemodynamic effects of low-dose endotoxin and acute lung injury. | 1998 | Am. J. Respir. Crit. Care Med. | pmid:9620928 |
| O'Connor BJ et al. | Inhibitory effect of UK,74505, a potent and specific oral platelet activating factor (PAF) receptor antagonist, on airway and systemic responses to inhaled PAF in humans. | 1994 | Am. J. Respir. Crit. Care Med. | pmid:8025768 |
| Davì G et al. | Enhanced thromboxane biosynthesis in patients with chronic obstructive pulmonary disease. The Chronic Obstructive Bronchitis and Haemostasis Study Group. | 1997 | Am. J. Respir. Crit. Care Med. | pmid:9412557 |
| Jiang XW et al. | Effects of low-dose Beraprost sodium, a stable prostaglandin I2 analogue, on reperfusion injury to rabbit lungs. | 1998 | Am. J. Respir. Crit. Care Med. | pmid:9817723 |
| Praticò D et al. | Chronic obstructive pulmonary disease is associated with an increase in urinary levels of isoprostane F2alpha-III, an index of oxidant stress. | 1998 | Am. J. Respir. Crit. Care Med. | pmid:9847257 |
| Gust R et al. | Response to inhaled nitric oxide in acute lung injury depends on distribution of pulmonary blood flow prior to its administration. | 1999 | Am. J. Respir. Crit. Care Med. | pmid:9927374 |
| Imai Y et al. | Inflammatory chemical mediators during conventional ventilation and during high frequency oscillatory ventilation. | 1994 | Am. J. Respir. Crit. Care Med. | pmid:7952613 |
| Degges RD et al. | Pulmonary hypertensive effect of heparin and protamine interaction: evidence for thromboxane B2 release from the lung. | 1987 | Am. J. Surg. | pmid:3425821 |
| Myers SI and Hernandez R | Leukotriene C4 regulation of splanchnic blood flow during ischemia. | 1994 | Am. J. Surg. | pmid:8209929 |
| O'Neill PA et al. | Role of renal sympathetic nerve activity in renal failure associated with obstructive jaundice in the rat. | 1991 | Am. J. Surg. | pmid:1862825 |
| Tanowitz HB et al. | Enhanced platelet adherence and aggregation in Chagas' disease: a potential pathogenic mechanism for cardiomyopathy. | 1990 | Am. J. Trop. Med. Hyg. | pmid:2121055 |
| Bottoms GD et al. | Thromboxane, prostaglandin I2 (epoprostenol), and the hemodynamic changes in equine endotoxin shock. | 1982 | Am. J. Vet. Res. | pmid:7049018 |
| MacKay RJ et al. | Effect of a conjugate of polymyxin B-dextran 70 in horses with experimentally induced endotoxemia. | 1999 | Am. J. Vet. Res. | pmid:9918150 |
| Giraudel JM et al. | Development of in vitro assays for the evaluation of cyclooxygenase inhibitors and predicting selectivity of nonsteroidal anti-inflammatory drugs in cats. | 2005 | Am. J. Vet. Res. | pmid:15900953 |
| Grauer GF et al. | Effects of dietary n-3 fatty acid supplementation versus thromboxane synthetase inhibition on gentamicin-induced nephrotoxicosis in healthy male dogs. | 1996 | Am. J. Vet. Res. | pmid:8725828 |
| Morris DD et al. | Proadifen-induced production of prostacyclin by equine peritoneal macrophages. | 1989 | Am. J. Vet. Res. | pmid:2499232 |
| Morris DD et al. | Endotoxin-induced changes in plasma concentrations of thromboxane and prostacyclin in neonatal calves given antiserum to a mutant Escherichia coli (J-5). | 1986 | Am. J. Vet. Res. | pmid:3541703 |
| Hoh CM et al. | Evaluation of effects of low-dose aspirin administration on urinary thromboxane metabolites in healthy dogs. | 2011 | Am. J. Vet. Res. | pmid:21801060 |
| Semrad SD et al. | Pharmacokinetics of and serum thromboxane suppression by flunixin meglumine in healthy foals during the first month of life. | 1993 | Am. J. Vet. Res. | pmid:8116942 |
| Gerros TC et al. | Effect of dose and method of administration of endotoxin on cell mediator release in neonatal calves. | 1993 | Am. J. Vet. Res. | pmid:8116949 |
| Semrad SD et al. | Hypertension in bulls and steers anesthetized with guaifenesin-thiobarbiturate-halothane combination. | 1986 | Am. J. Vet. Res. | pmid:3740628 |
| Streppa HK et al. | Cyclooxygenase selectivity of nonsteroidal anti-inflammatory drugs in canine blood. | 2002 | Am. J. Vet. Res. | pmid:16206787 |
| Longhofer SL et al. | Effects of a specific thromboxane synthetase inhibitor on thromboxane generation and excretion in healthy dogs. | 1990 | Am. J. Vet. Res. | pmid:2240799 |
| Pratt HL et al. | Platelet aggregation, storage pool deficiency, and protein phosphorylation in mice with Chediak-Higashi syndrome. | 1991 | Am. J. Vet. Res. | pmid:1652907 |
| Ward DS et al. | Equine endotoxemia: cardiovascular, eicosanoid, hematologic, blood chemical, and plasma enzyme alterations. | 1987 | Am. J. Vet. Res. | pmid:3307560 |
| Baskett A et al. | Effect of pentoxifylline, flunixin meglumine, and their combination on a model of endotoxemia in horses. | 1997 | Am. J. Vet. Res. | pmid:9361895 |
| Barton MH et al. | Effects of pentoxifylline infusion on response of horses to in vivo challenge exposure with endotoxin. | 1997 | Am. J. Vet. Res. | pmid:9361896 |
| Kay-Mugford T and Conlon P | Possible inconsistencies in study on cyclooxygenase. | 1999 | Am. J. Vet. Res. | pmid:10188806 |
| Gershwin LJ and Giri SN | Effects of allergen challenge on plasma concentrations of prostaglandins, thromboxane B2, and histamine in calves infected with bovine respiratory syncytial virus. | 1992 | Am. J. Vet. Res. | pmid:1416375 |
| Semrad SD et al. | Effects of concurrent administration of phenylbutazone and flunixin meglumine on pharmacokinetic variables and in vitro generation of thromboxane B2 in mares. | 1993 | Am. J. Vet. Res. | pmid:8291770 |
| Semrad SD et al. | Pharmacokinetics and effects of repeated administration of phenylbutazone in neonatal calves. | 1993 | Am. J. Vet. Res. | pmid:8291771 |
| Wooten JG et al. | Cyclooxygenase expression and prostanoid production in pyloric and duodenal mucosae in dogs after administration of nonsteroidal anti-inflammatory drugs. | 2008 | Am. J. Vet. Res. | pmid:18380576 |
| Cargile JL et al. | Effects of tumor necrosis factor blockade on interleukin 6, lactate, thromboxane, and prostacyclin responses in miniature horses given endotoxin. | 1995 | Am. J. Vet. Res. | pmid:8585654 |
| Baxter GM and Moore JN | Effect of aspirin on ex vivo generation of thromboxane in healthy horses. | 1987 | Am. J. Vet. Res. | pmid:3826831 |
| Grauer GF et al. | Effects of a thromboxane synthetase inhibitor on established immune complex glomerulonephritis in dogs. | 1992 | Am. J. Vet. Res. | pmid:1388004 |
| Ricketts AP et al. | Evaluation of selective inhibition of canine cyclooxygenase 1 and 2 by carprofen and other nonsteroidal anti-inflammatory drugs. | 1998 | Am. J. Vet. Res. | pmid:9829404 |