Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Escherichia coli Infections D004927 17 associated lipids
Scleroderma, Systemic D012595 16 associated lipids
Ulcer D014456 16 associated lipids
Atrial Fibrillation D001281 16 associated lipids
Blister D001768 16 associated lipids
Pulmonary Disease, Chronic Obstructive D029424 16 associated lipids
Adenomatous Polyposis Coli D011125 16 associated lipids
Celiac Disease D002446 16 associated lipids
Vascular Diseases D014652 16 associated lipids
Choline Deficiency D002796 16 associated lipids
Per page 10 20 50 100 | Total 293

PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

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Per page 10 20 50 100 | Total 6367
Authors Title Published Journal PubMed Link
Hsu MF et al. Blockade of cytosolic phospholipase A(2) and 5-lipoxygenase activation in neutrophils by a natural isoflavanquinone abruquinone A. 2008 Eur. J. Pharmacol. pmid:18834875
Kaneko I et al. Prostaglandin F(2alpha) regulates cytokine responses of mast cells through the receptors for prostaglandin E. 2008 Biochem. Biophys. Res. Commun. pmid:18190789
Parsons JP et al. Airway inflammation in exercise-induced bronchospasm occurring in athletes without asthma. 2008 J Asthma pmid:18569228
Natarajan G et al. Chorioamnionitis and ontogeny of circulating prostaglandin and thromboxane in preterm infants. 2008 Am J Perinatol pmid:18726836
Santilli F et al. Circulating endothelial progenitor cells and residual in vivo thromboxane biosynthesis in low-dose aspirin-treated polycythemia vera patients. 2008 Blood pmid:18541722
Mitsopoulos P et al. Effectiveness of liposomal-N-acetylcysteine against LPS-induced lung injuries in rodents. 2008 Int J Pharm pmid:18694812
Yokoyama Y et al. Up-regulated thromboxane production in the rat liver with biliary obstruction does not contribute to promote hepatic injury. 2008 Shock pmid:17885643
Meen O et al. No case of COX-1-related aspirin resistance found in 289 patients with symptoms of stable CHD remitted for coronary angiography. 2008 Scand. J. Clin. Lab. Invest. pmid:17934975
Zhao S et al. Predominant basal directional release of thromboxane, but not prostacyclin, by placental trophoblasts from normal and preeclamptic pregnancies. 2008 Placenta pmid:17936899
Heistein LC et al. Aspirin resistance in children with heart disease at risk for thromboembolism: prevalence and possible mechanisms. 2008 Pediatr Cardiol pmid:17896127
Larson MK et al. Effects of omega-3 acid ethyl esters and aspirin, alone and in combination, on platelet function in healthy subjects. 2008 Thromb. Haemost. pmid:18841286
Lessa A et al. The effect of pentoxifylline on the pulmonary response to high tidal volume ventilation in rats. 2008 Pulm Pharmacol Ther pmid:17251044
Aslam R et al. Lipoproteins inhibit platelet aggregation and arachidonic acid metabolism in experimental hypercholesterolaemia. 2008 Clin. Exp. Pharmacol. Physiol. pmid:18215184
Toscano CD et al. NMDA-induced seizure intensity is enhanced in COX-2 deficient mice. 2008 Neurotoxicology pmid:18834901
Lee CR et al. Cyclooxygenase polymorphisms and risk of cardiovascular events: the Atherosclerosis Risk in Communities (ARIC) study. 2008 Clin. Pharmacol. Ther. pmid:17495879
Awad H et al. Intracellular and extracellular expression of the major inducible 70kDa heat shock protein in experimental ischemia-reperfusion injury of the spinal cord. 2008 Exp. Neurol. pmid:18511046
Basselin M et al. Chronic administration of valproic acid reduces brain NMDA signaling via arachidonic acid in unanesthetized rats. 2008 Neurochem. Res. pmid:18461450
Dobaczewski M et al. Targeting the urine and plasma determinants of thromboxane A2 metabolism in detection of aspirin effectiveness. 2008 Blood Coagul. Fibrinolysis pmid:18600093
Rossoni G et al. Combined simvastatin-manidipine protect against ischemia-reperfusion injury in isolated hearts from normocholesterolemic rats. 2008 Eur. J. Pharmacol. pmid:18442813
Graff J et al. Significant effects of tipranavir on platelet aggregation and thromboxane B2 formation in vitro and in vivo. 2008 J. Antimicrob. Chemother. pmid:18156609
Delgado-Lista J et al. Chronic dietary fat intake modifies the postprandial response of hemostatic markers to a single fatty test meal. 2008 Am. J. Clin. Nutr. pmid:18258620
Tanen DA et al. Comparison of oral aspirin versus topical applied methyl salicylate for platelet inhibition. 2008 Ann Pharmacother pmid:18698012
Nocun M et al. French maritime pine bark extract Pycnogenol reduces thromboxane generation in blood from diabetic male rats. 2008 Biomed. Pharmacother. pmid:17698319
Park MK et al. Antiplatelet and antithrombotic activity of indole-3-carbinol in vitro and in vivo. 2008 Phytother Res pmid:17724769
Rao CV et al. Pharmacokinetic and pharmacodynamic study of NO-donating aspirin in F344 rats. 2008 Int. J. Oncol. pmid:18813794
Rajec J et al. Biochemical evaluation of the antiplatelet effect of aspirin in patients at different levels of cardiovascular risk. 2008 Bratisl Lek Listy pmid:18814431
Helgason CM et al. Platelet aggregation and recruitment with aspirin-clopidogrel therapy. 2008 Cerebrovasc. Dis. pmid:18349532
Momen A et al. Local prostaglandin blockade attenuates muscle mechanoreflex-mediated renal vasoconstriction during muscle stretch in humans. 2008 Am. J. Physiol. Heart Circ. Physiol. pmid:18326807
Skoglund C et al. C-reactive protein and C1q regulate platelet adhesion and activation on adsorbed immunoglobulin G and albumin. 2008 Immunol. Cell Biol. pmid:18332893
Menzies D et al. Effect of aspirin on airway inflammation and pulmonary function in patients with persistent asthma. 2008 J. Allergy Clin. Immunol. pmid:18313127
Geske FJ et al. AspirinWorks: a new immunologic diagnostic test for monitoring aspirin effect. 2008 Mol Diagn Ther pmid:18288882
Selg E et al. Effects of selective and non-selective COX inhibitors on antigen-induced release of prostanoid mediators and bronchoconstriction in the isolated perfused and ventilated guinea pig lung. 2008 Prostaglandins Leukot. Essent. Fatty Acids pmid:18294831
Basselin M et al. Chronic carbamazepine administration attenuates dopamine D2-like receptor-initiated signaling via arachidonic acid in rat brain. 2008 Neurochem. Res. pmid:18302021
Signore C et al. Markers of oxidative stress and systemic vasoconstriction in pregnant women drinking > or =48 g of alcohol per day. 2008 Alcohol. Clin. Exp. Res. pmid:18715278
Roethig HJ et al. A 12-month, randomized, controlled study to evaluate exposure and cardiovascular risk factors in adult smokers switching from conventional cigarettes to a second-generation electrically heated cigarette smoking system. 2008 J Clin Pharmacol pmid:18319361
Al-Salam Z et al. The effect of dobutamine on platelet aggregatory function in newborn piglets with hypoxia and reoxygenation. 2008 Shock pmid:18323735
Park JW et al. 15,16-dihydrotanshinone I, a major component from Salvia miltiorrhiza Bunge (Dansham), inhibits rabbit platelet aggregation by suppressing intracellular calcium mobilization. 2008 Arch. Pharm. Res. pmid:18277607
Schwartz JI et al. Comparative inhibitory activity of etoricoxib, celecoxib, and diclofenac on COX-2 versus COX-1 in healthy subjects. 2008 J Clin Pharmacol pmid:18434566
Hasan J et al. Early postnatal ibuprofen and indomethacin effects in suckling and weanling rat kidneys. 2008 Prostaglandins Other Lipid Mediat. pmid:18096423
Ruan KH et al. An active triple-catalytic hybrid enzyme engineered by linking cyclo-oxygenase isoform-1 to prostacyclin synthase that can constantly biosynthesize prostacyclin, the vascular protector. 2008 FEBS J. pmid:19021758
Jiang H et al. The midnight-noon ebb-flow point selection for 30 cases of acute ischemic cerebrovascular diseases. 2008 J Tradit Chin Med pmid:19004202
Otani Y et al. Effects of the COX-2 inhibitor FK3311 on ischemia - reperfusion injury in the rat lung. 2007 May-Jun J Invest Surg pmid:17613692
Jiang J et al. Endothelin-1 blockade prevents COX2 induction and TXA2 production in the fructose hypertensive rat. 2007 Mar-Apr Can. J. Physiol. Pharmacol. pmid:17612651
Csanyi G et al. Lack of endothelium-derived hyperpolarizing factor (EDHF) up-regulation in endothelial dysfunction in aorta in diabetic rats. 2007 Jul-Aug Pharmacol Rep pmid:17901574
Komers R et al. Cyclo-oxygenase-2 inhibition attenuates the progression of nephropathy in uninephrectomized diabetic rats. 2007 Jan-Feb Clin. Exp. Pharmacol. Physiol. pmid:17201733
González-Correa JA et al. Gender differences in the effect of aspirin on retinal ischemia, prostanoid synthesis and nitric oxide production in experimental type 1-like diabetes. 2007 Aug-Sep Vascul. Pharmacol. pmid:17581795
Sood BG et al. PGE2/TXB2 imbalance in neonatal hypoxemic respiratory failure. 2007 Acta Paediatr. pmid:17376184
Li XM et al. [Physiological effects of cold and cool Chinese herbal medicine of channel tropism of stomach on rats with stomach-heat syndrome]. 2007 Zhongguo Zhong Yao Za Zhi pmid:17672345
Bogani P et al. Postprandial anti-inflammatory and antioxidant effects of extra virgin olive oil. 2007 Atherosclerosis pmid:16488419
Sekine S et al. Lowering systolic blood pressure and increases in vasodilator levels in SHR with oral alpha-linolenic acid administration. 2007 J Oleo Sci pmid:17898500