Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Escherichia coli Infections D004927 17 associated lipids
Scleroderma, Systemic D012595 16 associated lipids
Atrial Fibrillation D001281 16 associated lipids
Blister D001768 16 associated lipids
Pulmonary Disease, Chronic Obstructive D029424 16 associated lipids
Adenomatous Polyposis Coli D011125 16 associated lipids
Celiac Disease D002446 16 associated lipids
Vascular Diseases D014652 16 associated lipids
Choline Deficiency D002796 16 associated lipids
Ventricular Fibrillation D014693 16 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

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Per page 10 20 50 100 | Total 6367
Authors Title Published Journal PubMed Link
Clark KE et al. Effect of bisenoic prostaglandins and arachidonic acid on the uterine vasculature of pregnant sheep. 1982 Am. J. Obstet. Gynecol. pmid:7065014
Schuette AH et al. Effect of lung thromboxane generation on regional blood flow during sheep bypass. 1982 Am. J. Physiol. pmid:7065206
Han P et al. Inhibition of platelet function of antiarrhythmic drugs, verapamil and disopyramide. 1982 Thromb. Haemost. pmid:7101234
Ylikorkala O and Viinikka L Effect of amnioscopy on concentrations of prostaglandin F2 alpha, prostacyclin and thromboxane in maternal plasma. 1982 Gynecol. Obstet. Invest. pmid:6954125
Fitzpatrick FA A radioimmunoassay for thromboxane B2. 1982 Meth. Enzymol. pmid:7132759
Maas RL et al. Quantitative assay of urinary 2,3-dinor thromboxane B2 by GC-MS. 1982 Meth. Enzymol. pmid:7132771
Pace-Asciak CR and Edwards NS Preparation of 2,3,4,5-tetranor-thromboxane B2, the major urinary catabolite of thromboxane B2 in the rat. 1982 Meth. Enzymol. pmid:7132772
Martin JF et al. Effect of acetylsalicylic acid on platelet aggregation and thromboxane B2 production in flowing aortic blood in the rat studied with a filter loop technique. 1982 Thromb. Res. pmid:6814004
Dorsch W et al. Mediator studies in skin blister fluid from patients with dual skin reactions after intradermal allergen injection. 1982 J. Allergy Clin. Immunol. pmid:6181112
Hadding U et al. Peritoneal macrophages release prostaglandin E and thromboxane B2 in response to C3b. 1982 Adv. Exp. Med. Biol. pmid:7158499
Addonizio VP et al. Inhibition of human platelet function by verapamil. 1982 Thromb. Res. pmid:7164035
Vargaftig BB et al. Adrenaline and PAF-acether synergize to trigger cyclooxygenase-independent activation of plasma-free human platelets. 1982 Thromb. Res. pmid:7164036
Numano F et al. Effects of thromboxane A2 injection on the rabbit coronary artery. II. The production of infarcts in cholesterol-fed animals. 1982 Exp. Mol. Pathol. pmid:6956517
Vlodavsky I et al. Platelet interaction with the extracellular matrix produced by cultured endothelial cells: a model to study the thrombogenicity of isolated subendothelial basal lamina. 1982 Thromb. Res. pmid:7179215
Deby-Dupont G et al. Release of thromboxane B2 during adult respiratory distress syndrome and its inhibition by non steroidal anti-inflammatory substances in man. 1982 Arch Int Pharmacodyn Ther pmid:7181589
Zipser RD and Martin K Urinary excretion of arterial blood prostaglandins and thromboxanes in man. 1982 Am. J. Physiol. pmid:6950668
Shohami E et al. [Thromboxane in rat brain following incomplete ischemia]. 1982 Harefuah pmid:7182317
Hamasaki Y et al. Hypoxia stimulates prostacyclin generation by dog lung in vitro. 1982 Prostaglandins Leukot Med pmid:7051045
Goldsmith JC and Needleman SW A comparative study of thromboxane and prostacyclin release from ex vivo and cultured bovine vascular endothelium. 1982 Prostaglandins pmid:6815717
Blackwell GJ et al. Prostacyclin prolongs viability of washed human platelets. 1982 Biochim. Biophys. Acta pmid:6291622
Karmali RA et al. Prostaglandin regulation of murine mammary tumor virus production: a basis for some of the glucocorticoid and prolactin actions on mammary tumor cell cultures. 1982 Prostaglandins Leukot Med pmid:6296884
Mehta J et al. Severe intracoronary thromboxane release preceding acute coronary artery occlusion. 1982 Prostaglandins Leukot Med pmid:6955814
Watanabe T et al. Characterization of the biosynthetic pathway of prostaglandin D2 in human platelet-rich plasma. 1982 J. Biol. Chem. pmid:6816798
Jaweed MM et al. Changes in thromboxane B2 and 6-keto-PGF1 alpha after direct electrical stimulation of the denervated rat gastrocnemius1,2. 1982 Prostaglandins Leukot Med pmid:6956927
Taube C et al. Enhanced thromboxane production in the aorta of spontaneously hypertensive rats in vitro. 1982 Prostaglandins Leukot Med pmid:6960370
Castaldi PA et al. Evidence for a platelet membrane defect in the myeloproliferative syndromes. 1982 Thromb. Res. pmid:6960545
Rachmilewitz D et al. Prostanoid synthesis by cultured peripheral blood mononuclear cells in inflammatory diseases of the bowel. 1982 Gastroenterology pmid:6949849
Krishnamurthi S et al. Effect of pyridoxal 5'-phosphate (PALP) on human platelet aggregation, dense granule release and thromboxane B2 generation--role of Schiff base formation. 1982 Thromb. Haemost. pmid:6891107
Capitanio A et al. Detection of circulating released platelets after renal transplantation. 1982 Transplantation pmid:6461116
Hall ER et al. The reduction of platelet thrombi on damaged vessel wall by a thromboxane synthetase inhibitor in rabbits. 1982 Thromb. Res. pmid:6891109
White JG and Rao GH Effects of a microtubule stabilizing agent on the response of platelets to vincristine. 1982 Blood pmid:6124288
Davì G et al. [Effects of flurbiprofen on the platelet function in patients with ischemic cardiopathy]. 1982 Cardiologia pmid:6892383
Chong BH et al. Heparin-induced thrombocytopenia: association of thrombotic complications with heparin-dependent IgG antibody that induces thromboxane synthesis in platelet aggregation. 1982 Lancet pmid:6128550
De Caterina R et al. [Effects of isosorbide dinitrate on platelet aggregation and production of thromboxane B2]. 1982 Cardiologia pmid:6892461
Ody C et al. 6-Ketoprostaglandin F1 alpha, prostaglandins E2, F2 alpha and thromboxane B2 production by endothelial cells, smooth muscle cells and fibroblasts cultured from piglet aorta. 1982 Biochim. Biophys. Acta pmid:6214281
Rock JA et al. Cul-de-sac fluid in women with endometriosis: fluid volume and prostanoid concentration during the proliferative phase of the cycle--days 8 to 12. 1982 Fertil. Steril. pmid:6953017
de Boer AC et al. Platelet release and thromboxane synthesis in symptomatic coronary artery disease. 1982 Circulation pmid:6212161
Mari D et al. Coagulation and platelet activation after retinal vein occlusions. 1982 Haemostasis pmid:6215293
Casey LC et al. Prevention of endotoxin-induced pulmonary hypertension in primates by the use of a selective thromboxane synthetase inhibitor, OKY 1581. 1982 J. Pharmacol. Exp. Ther. pmid:6896528
de Clerck F et al. Inhibition of 5-hydroxytryptamine-induced and -amplified human platelet aggregation by ketanserin (R 41 468), a selective 5-HT2-receptor antagonist. 1982 Agents Actions pmid:6215842
Chen LS et al. Changes of plasma 6-keto-PGF1 alpha and thromboxane B2 levels and platelet aggregation after tourniquet ischemia on the upper limb in normal subjects and patients with ischemic heart disease. 1982 Jpn. Circ. J. pmid:6896534
Mehta J and Mehta P Effects of propranolol therapy on platelet release and prostaglandin generation in patients with coronary heart disease. 1982 Circulation pmid:6216027
Stuart MJ and Allen JB Arachidonic acid metabolism in the neonatal platelet. 1982 Pediatrics pmid:6804924
Evans CA et al. Gestational changes in prostanoid concentrations in intrauterine tissues and fetal fluids from pregnant sheep, and the relation to prostanoid output in vitro. 1982 Biol. Reprod. pmid:6896829
Koyama I et al. Release of 6-keto-prostaglandin F1 alpha and thromboxane B2 from mouse peritoneal macrophages during their adhesion and spreading on a glass surface. 1982 Prostaglandins pmid:6896924
Uderman HD et al. Attenuation of the development of hypertension in spontaneously hypertensive rats by the thromboxane synthetase inhibitor, 4'-(imidazol-1-yl) acetophenone. 1982 Prostaglandins pmid:6897296
Katsumata M et al. Diphenylhydantoin: an alternative ligand of a glucocorticoid receptor affecting prostaglandin generation in A/J mice. 1982 Science pmid:6897299
Mehta P et al. Thromboxane and prostacyclin generation by intact human vessels in response to balloon catheter trauma. 1982 Prostaglandins Leukot Med pmid:6217465
Koyama I et al. [Production of 6-keto-prostaglandin F1 alpha and thromboxane B2 in mouse peritoneal macrophages during preparation of the cells]. 1982 Yakugaku Zasshi pmid:6897423
Wilson L et al. Alterations in reproductive tissue prostaglandins E and F, 6-keto-prostaglandin F1 alpha and thromboxane B2 with gestational age in the rat. 1982 Biol. Reprod. pmid:6897617
Randall MJ and Wilding RI Acute arterial thrombosis in rabbits: reduced platelet accumulation after treatment with thromboxane synthetase inhibitor dazoxiben hydrochloride, (UK-37, 248-01). 1982 Thromb. Res. pmid:6897751
De Caterina R et al. [Effect of isosorbide dinitrate on platelet aggregation and production of thromboxane B2]. 1982 Cardiologia pmid:6927441
Davì G et al. [Effects of flurbiprofen on platelet function in patients with ischemic cardiomyopathy]. 1982 Cardiologia pmid:6927457
Hwang DH and Donovan J In vitro and in vivo effects of vitamin E on arachidonic acid metabolism in rat platelets. 1982 J. Nutr. pmid:6806455
Lecompte T et al. Interference of transmethylation inhibitors with thromboxane synthesis in rat platelets. 1982 Biochem. Biophys. Res. Commun. pmid:6809005
Meydani SN and Dupont J Effect of zinc deficiency on prostaglandin synthesis in different organs of the rat. 1982 J. Nutr. pmid:7045297
Srivastava KC and Awasthi KK A comparative study on the effect of cis (oleic, linoleic) and trans (elaidic, linoelaidic) fatty acids on the in vitro prostaglandin biosynthesis in human blood platelets from (1-14C) arachidonic acid. 1982 Prostaglandins Leukot Med pmid:6818563
Watkins WD et al. Thromboxane and pulmonary hypertension following E. coli endotoxin infusion in sheep: effect of an imidazole derivative. 1982 Prostaglandins pmid:7048422
Kelley VE et al. Effect of ibuprofen, a fatty acid cyclooxygenase inhibitor, on murine lupus. 1982 Clin. Immunol. Immunopathol. pmid:6819912
Miller OV et al. Acetyl glycerylphosphorylcholine inhibition of prostaglandin I2-stimulated adenosine 3',5'-cyclic monophosphate levels in human platelets. Evidence for thromboxane A2 dependence. 1982 Biochim. Biophys. Acta pmid:6285985
Jackson CA et al. Relationship between platelet aggregation, thromboxane synthesis and albumin concentration in nephrotic syndrome. 1982 Br. J. Haematol. pmid:6810912
Cerletti C et al. Non-steroidal anti-inflammatory drugs react with two sites on platelet cyclo-oxygenase. Evidence from "in vivo" drug interaction studies in rats. 1982 Biochim. Biophys. Acta pmid:6799004
Levy-Toledano S et al. Human platelet activation in the absence of aggregation: a calcium-dependent phenomenon independent of thromboxane formation. 1982 Blood pmid:6803854
Rettkowski W et al. Studies of the influence of nitroglycerin on the synthesis of prostaglandins and thromboxane A2 and on platelet aggregation. 1982 Arzneimittelforschung pmid:6805480
Panossian A et al. On the mechanism of biosynthesis of leukotrienes and related compounds. 1982 FEBS Lett. pmid:6297982
Michelassi F et al. Leukotriene D4: a potent coronary artery vasoconstrictor associated with impaired ventricular contraction. 1982 Science pmid:6808665
Landgraf-Leurs MM et al. Aggregation and thromboxane formation by platelets and vascular prostacyclin production from BB rats. An animal model for type I diabetes. 1982 Prostaglandins pmid:6812171
Bodzenta A et al. Platelet malondialdehyde and plasma thromboxane B2 formation in patients with obliterative arteriosclerosis of the lower limbs. 1982 Folia Haematol. Int. Mag. Klin. Morphol. Blutforsch. pmid:6188668
Nugent WC et al. Prostaglandin response to intravenous nitroglycerin. 1982 J. Surg. Res. pmid:6810023
Harada Y et al. Changes in the levels of prostaglandins and thromboxane and their roles in the accumulation of exudate in rat carrageenin-induced pleurisy--a profile analysis using gas chromatography-mass spectrometry. 1982 Prostaglandins pmid:6889754
Yoshimoto T and Yamamoto S Partial purification and assay of thromboxane A synthase from bovine platelets. 1982 Meth. Enzymol. pmid:6890138
Miller JL et al. Arachidonic acid metabolism in guinea pig megakaryocytes. 1982 Biochem. Biophys. Res. Commun. pmid:6812584
Tai HH Assay of thromboxane A synthase inhibitors. 1982 Meth. Enzymol. pmid:6890139
Rothberg KG and Hitchcock M In vitro biosynthesis of cyclooxygenase metabolites in ovalbumin-sensitized and control lungs of guinea pigs. 1982 Biochem. Pharmacol. pmid:6812589
Watkins WD et al. Thromboxane and prostacyclin changes during cardiopulmonary bypass with and without pulsatile flow. 1982 J. Thorac. Cardiovasc. Surg. pmid:6980332
Malemud CJ et al. Correlation of the biosynthesis of prostaglandin and cyclic AMP in monolayer cultures of rabbit articular chondrocytes. 1982 Biochim. Biophys. Acta pmid:6280776
Robinson C et al. Thromboxane B2 uptake and metabolism in isolated perfused lung. Identification and comparison with prostaglandin F2 alpha. 1982 Biochim. Biophys. Acta pmid:6751406
Xiu RJ et al. Anisodamine inhibits thromboxane synthesis, granulocyte aggregation, and platelet aggregation. A possible mechanism for its efficacy in bacteremic shock. 1982 JAMA pmid:7057538
Kelton JG et al. Sex related differences in platelet function: the effect of aspirin. 1982 Blood pmid:7059670
Kelton JG et al. Sex-related differences in the efficacy of acetylsalicylic acid (ASA) : the absorption of ASA and its effect on collagen-induced thromboxane B2 generation. 1981 Oct 1-15 Thromb. Res. pmid:7330835
Randall MJ et al. UK-37, 248, a novel, selective thromboxane synthetase inhibitor with platelet anti-aggregatory and anti-thrombotic activity. 1981 Jul 1-15 Thromb. Res. pmid:6795753
Tsuboi T et al. Effect of gliclazide on prostaglandin and thromboxane synthesis in guinea-pig platelets. 1981 Jan 1-15 Thromb. Res. pmid:7233394
Ylikorkala O et al. Increased prostacyclin and thromboxane production in man during cardiopulmonary bypass. 1981 J. Thorac. Cardiovasc. Surg. pmid:7019583
Hales CA et al. Role of thromboxane and prostacyclin in pulmonary vasomotor changes after endotoxin in dogs. 1981 J. Clin. Invest. pmid:7021593
Hyman AL et al. Prostaglandins and the lung. 1981 Med. Clin. North Am. pmid:7024664
Rosenfeld J et al. Extractive alkylation of prostaglandins. 1981 Prostaglandins pmid:7010456
Tanaka M et al. Increased prostacyclin synthesizing activity in human ripening uterine cervix. 1981 Prostaglandins pmid:7010458
Gonzalez-Crussi F et al. Prostaglandins in histiocytosis-X. PG synthesis by histiocytosis-X cells. 1981 Am. J. Clin. Pathol. pmid:6970520
Araki H et al. Mechanism of protection against arachidonate induced sudden death by glucocorticoid. 1981 Prostaglandins pmid:7232764
Tyler HM et al. Administration to man of UK-37,248-01, a selective inhibitor of thromboxane synthetase. 1981 Lancet pmid:6110861
Vermylen J et al. Thromboxane synthetase inhibition as antithrombotic strategy. 1981 Lancet pmid:6112447
Smith MC and Dunn MJ Impaired platelet thromboxane production in renal failure. 1981 Nephron pmid:7329487
Lagarde M et al. Inhibition of thrombin-induced platelet arachidonic acid release by 15-hydroperoxy-arachidonic acid. 1981 Biochem. Biophys. Res. Commun. pmid:7259783
Livio M et al. Differential effects of itanoxone--a new hypolipidemic and hypouricemic drug--on platelet and vascular prostaglandin generation in rats. 1981 Atherosclerosis pmid:7259827
Hirsh PD et al. Release of prostaglandins and thromboxane into the coronary circulation in patients with ischemic heart disease. 1981 N. Engl. J. Med. pmid:6894016
Allan G and Levi R Thromboxane and prostacyclin release during cardiac immediate hypersensitivity reactions in vitro. 1981 J. Pharmacol. Exp. Ther. pmid:6894166
Sobel M et al. Circulating platelet products in unstable angina pectoris. 1981 Circulation pmid:6450001
Taylor L et al. Prostaglandin production and cellular aging. 1981 Mech. Ageing Dev. pmid:6946268
Mezzano D et al. Evidence that platelet buoyant density, but not size, correlates with platelet age in man. 1981 Am. J. Hematol. pmid:7270546
Strano A et al. Thromboxane formation by platelets and platelet sensitivity to prostacyclin in patients with acute myocardial infarction. 1981 Thromb. Haemost. pmid:7036402