Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

Cross Reference

Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Autoimmune Diseases D001327 27 associated lipids
Endotoxemia D019446 27 associated lipids
Gastritis D005756 27 associated lipids
Gastrointestinal Hemorrhage D006471 27 associated lipids
Angina Pectoris D000787 27 associated lipids
Ventricular Remodeling D020257 28 associated lipids
Vitamin E Deficiency D014811 29 associated lipids
Kidney Diseases D007674 29 associated lipids
Endometriosis D004715 29 associated lipids
Proteinuria D011507 30 associated lipids
Stroke D020521 32 associated lipids
Hypothyroidism D007037 32 associated lipids
Hypertension, Pulmonary D006976 32 associated lipids
Uremia D014511 33 associated lipids
Ventricular Dysfunction, Left D018487 33 associated lipids
Burns D002056 34 associated lipids
Acute Kidney Injury D058186 34 associated lipids
Anemia, Sickle Cell D000755 34 associated lipids
Spinal Cord Injuries D013119 34 associated lipids
Glomerulonephritis D005921 35 associated lipids
Per page 10 20 50 100 | Total 293

PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

Download all related citations
Per page 10 20 50 100 | Total 6367
Authors Title Published Journal PubMed Link
Bockman RS Prostaglandin production by human blood monocytes and mouse peritoneal macrophages: synthesis dependent on in vitro culture conditions. 1981 Prostaglandins pmid:6782622
Rittenhouse-Simmons S Differential activation of platelet phospholipases by thrombin and ionophore A23187. 1981 J. Biol. Chem. pmid:6783655
Galli C et al. Differential effects of dietary fatty acids on the accumulation of arachidonic acid and its metabolic conversion through the cyclooxygenase and lipoxygenase in platelets and vascular tissue. 1981 Lipids pmid:6783805
Rao GH et al. Effect of Amrinone, a cardiotonic drug, on hemodynamics and platelet function. 1981 Prostaglandins Med pmid:6784136
Strand JC et al. Effect of imidazole on renal function in unilateral ureteral-obstructed rat kidneys. 1981 Am. J. Physiol. pmid:6787931
Stuart MJ et al. Abnormal platelet function and arachidonate metabolism in chronic idiopathic thrombocytopenic purpura. 1981 Blood pmid:6788109
Kass MA et al. Prostaglandin and thromboxane synthesis by microsomes of inflamed rabbit ciliary body--iris. 1981 Invest. Ophthalmol. Vis. Sci. pmid:7216665
Sakio H et al. [Release of thromboxane A2 during hemorrhagic shock (author's transl)]. 1981 Masui pmid:7218508
Kawaguchi H et al. Thromboxane B2 biosynthesis and phospholipids hydrolysis in platelets from hypercholesterolemic rabbits. 1981 Lipids pmid:7219079
Sirois P et al. Comparative effects of leukotriene B4, prostaglandins I2 and E2, 6-keto-PGF1 alpha thromboxane B2 and histamine on selected smooth muscle preparations. 1981 J. Pharm. Pharmacol. pmid:6115037
Handin RI and Alexander RW Humoral heartache -- do platelets have a role? 1981 N. Engl. J. Med. pmid:7010170
Robertson RM et al. Thromboxane A2 in vasotonic angina pectoris: evidence from direct measurements and inhibitor trials. 1981 N. Engl. J. Med. pmid:7010173
Hladovec J Prostaglandins and endothelial stability. 1981 Arzneimittelforschung pmid:7011332
Sananès N et al. A role for prostaglandins in decidualization of the rat uterus. 1981 J. Endocrinol. pmid:7012263
Coker SJ et al. Aspirin inhibits the early myocardial release of thromboxane B2 and ventricular ectopic activity following acute coronary artery occlusion in dogs. 1981 Br. J. Pharmacol. pmid:7284679
Tyler HM et al. Administration to man of UK-37,248-01, a selective inhibitor of thromboxane synthetase. 1981 Lancet pmid:6110861
Vermylen J et al. Thromboxane synthetase inhibition as antithrombotic strategy. 1981 Lancet pmid:6112447
Feuerstein N et al. 3-deazaadenosine, a transmethylase inhibitor, suppresses the effect of lipopolysaccharide on release of prostacyclin and thromboxane. 1981 J. Pharm. Pharmacol. pmid:6115021
Fasce L et al. [Effects of glucocorticoids on the gastrointestinal tract of normal rats and rats deficient in endogenous prostaglandins]. 1981 Boll. Soc. Ital. Biol. Sper. pmid:7295403
Tada M et al. Elevation of thromboxane B2 levels in patients with classic and variant angina Pectoris. 1981 Circulation pmid:7296786
Foegh ML et al. Urine i-TXB2 in renal allograft rejection. 1981 Lancet pmid:6115199
McManus LM et al. Acetyl glyceryl ether phosphorylcholine. Intravascular alterations following intravenous infusion into the baboon. 1981 Lab. Invest. pmid:7300244
Uyama O et al. Plasma concentrations of thromboxane B2 in patients with hypertension or cerebrovascular disease. 1981 Prostaglandins Med pmid:7302001
Rifkin BR and Tai HH Elevated thromboxane B2 levels in periodontal disease. 1981 J. Periodont. Res. pmid:6453981
Mehta J and Mehta P Significance of platelet function and thromboxane B2 levels across the human myocardial vascular bed. 1981 Acta Med. Scand. Suppl. pmid:6948499
Stenson WF et al. Metabolism of exogenous arachidonic acid by murine macrophage-like tumor cell lines. 1981 Prostaglandins pmid:6803301
Rubenstein MD et al. Platelet activation in clinical coronary artery disease and spasm. 1981 Am. Heart J. pmid:6455912
Walker ID et al. A double blind study of prostacyclin in cardiopulmonary bypass surgery. 1981 Br. J. Haematol. pmid:6457624
Capitanio A et al. Platelet abnormalities in renal transplantation. 1981 Proc Eur Dial Transplant Assoc pmid:6460244
Kelly KL and Laychock SG Prostaglandin synthesis and metabolism in isolated pancreatic islets of the rat. 1981 Prostaglandins pmid:6803305
Ylikorkala O and Viinikka L Prostacyclin, thromboxane, and prostaglandin F2 alpha in maternal plasma during breast-feeding. 1981 Am. J. Obstet. Gynecol. pmid:7011034
Harms BA et al. Prostaglandin release and altered microvascular integrity after burn injury. 1981 J. Surg. Res. pmid:6895238
Ylikorkala O et al. Amniotic fluid prostacyclin and thromboxane in normal, preeclamptic, and some other complicated pregnancies. 1981 Am. J. Obstet. Gynecol. pmid:6895277
Ishihara Y et al. [Effect of hypoxemia and pulmonary thromboembolism on plasma levels of 6-keto PGF 1 alpha, TxB, histamine and serotonin in anesthetized dogs (author's transl)]. 1981 Nihon Kyobu Shikkan Gakkai Zasshi pmid:6895531
Kinney EL and Demers LM Plasma 6 keto PGE1 alpha concentration in Raynaud's phenomenon. 1981 Prostaglandins Med pmid:6895673
Barnett AH et al. Circulating prostanoid levels, both basal and during the chlorpropamide alcohol flush, in non-insulin dependent diabetes. 1981 Clin. Endocrinol. (Oxf) pmid:6895721
She HS et al. Metabolism of prostaglandin endoperoxide by microsomes from cat lung. 1981 Prostaglandins pmid:6894797
Agradi E et al. In vitro effects of synthetic antioxidants and vitamin E on arachidonic acid metabolism and thromboxane formation in human platelets and on platelet aggregation. 1981 Prostaglandins pmid:6794104
Russell NH et al. Platelet adenine nucleotides and arachidonic acid metabolism in the myeloproliferative disorders. 1981 Thromb. Res. pmid:6794179
Beck N and Shaw JO Thromboxane B2 and prostaglandin E2 in the K+-depleted rat kidney. 1981 Am. J. Physiol. pmid:7468800
Hwang DH et al. In vitro and in vivo effects of ethanol on the formation of endoperoxide metabolites in rat platelets. 1981 Lipids pmid:6792442
Shaw JO Effects of extracellular Ca2+ and the intracellular Ca2+ antagonist 8-(n,n-diethylamino)octyl-3,4,5-trimethoxybenzoate on rabbit platelet conversion of arachidonic acid into thromboxane. 1981 Prostaglandins pmid:6789402
Tulenko TN The actions of prostaglandins and cyclo-oxygenase inhibition on the resistance vessels supplying the human fetal placenta. 1981 Prostaglandins pmid:6794096
Ingerman-Wojenski C et al. Prostacyclin production in rabbit arteries in situ: inhibition by arachidonic acid-induced endothelial cell damage or by low-dose aspirin. 1981 Prostaglandins pmid:6789404
Williamson EM et al. Studies on the mechanism of action of 12-deoxyphorbolphenylacetate, a potent platelet aggregating tigliane ester. 1981 Biochem. Pharmacol. pmid:6794576
Ylikorkala O et al. Prostacyclin and thromboxane in diabetes. 1981 Br Med J (Clin Res Ed) pmid:6794795
Lee SH et al. Prostacyclin and thromboxane A2 in thrombotic thrombocytopenic purpura. 1981 Br Med J (Clin Res Ed) pmid:6797537
Feuerstein N and Ramwell PW OKY-1581, a potential selective thromboxane synthetase inhibitor. 1981 Eur. J. Pharmacol. pmid:7195815
Satoh H et al. Influence of angiotensins (I, II & III) on prostaglandin production by minced rat renal medulla. 1981 Prostaglandins pmid:7197382
Steinhauer HB and Hertting G Lowering of the convulsive threshold by non-steroidal anti-inflammatory drugs. 1981 Eur. J. Pharmacol. pmid:7202518