Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Pulmonary Embolism D011655 5 associated lipids
Ductus Arteriosus, Patent D004374 5 associated lipids
beta-Thalassemia D017086 5 associated lipids
Granulomatosis with Polyangiitis D014890 5 associated lipids
Placenta Diseases D010922 5 associated lipids
Intracranial Embolism and Thrombosis D002542 5 associated lipids
Hypoalphalipoproteinemias D052456 5 associated lipids
Facial Pain D005157 5 associated lipids
Bartter Syndrome D001477 5 associated lipids
Abortion, Habitual D000026 5 associated lipids
Mastocytosis D008415 5 associated lipids
Hypercapnia D006935 5 associated lipids
Aortic Aneurysm, Abdominal D017544 5 associated lipids
Respiration Disorders D012120 5 associated lipids
Asthenia D001247 5 associated lipids
Purpura, Schoenlein-Henoch D011695 5 associated lipids
Sclerosis D012598 5 associated lipids
Heart Valve Diseases D006349 4 associated lipids
Streptococcal Infections D013290 4 associated lipids
Retinal Diseases D012164 4 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

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Authors Title Published Journal PubMed Link
Zhou Z et al. Mechanisms underlying uridine adenosine tetraphosphate-induced vascular contraction in mouse aorta: Role of thromboxane and purinergic receptors. 2015 Vascul. Pharmacol. pmid:25921923
Al-Husseini A et al. Increased eicosanoid levels in the Sugen/chronic hypoxia model of severe pulmonary hypertension. 2015 PLoS ONE pmid:25785937
Mateu A et al. Cross-talk between TLR4 and PPARγ pathways in the arachidonic acid-induced inflammatory response in pancreatic acini. 2015 Int. J. Biochem. Cell Biol. pmid:26510582
Lourenço AL et al. Synthesis and antiplatelet activity of antithrombotic thiourea compounds: biological and structure-activity relationship studies. 2015 Molecules pmid:25903367
Sahota T et al. Model-based prediction of the acute and long-term safety profile of naproxen in rats. 2015 Br. J. Pharmacol. pmid:25884765
Violi F et al. Reply: platelet activation and pneumonia: is soluble p-selectin the right marker? 2015 J. Am. Coll. Cardiol. pmid:25857924
Gurbel PA et al. Platelet activation and pneumonia: is soluble p-selectin the right marker? 2015 J. Am. Coll. Cardiol. pmid:25857923
Violi F et al. Reply: myocardial infarction in patients with pneumonia. 2015 J. Am. Coll. Cardiol. pmid:25857922
Savas G and Kalay N Myocardial infarction in patients with pneumonia. 2015 J. Am. Coll. Cardiol. pmid:25857921
Santos-Gallego CG and Badimon J Reply: platelets interplay between pneumonia and cardiovascular events: establishing a link? 2015 J. Am. Coll. Cardiol. pmid:25857920
Violi F et al. Reply: platelets interplay between pneumonia and cardiovascular events: establishing a link? 2015 J. Am. Coll. Cardiol. pmid:25857919
Khan AR et al. Platelet activation and myocardial infarction in patients with pneumonia: are statins the answer? 2015 J. Am. Coll. Cardiol. pmid:25857918
Gavriilaki E et al. Platelets interplay between pneumonia and cardiovascular events: establishing a link? 2015 J. Am. Coll. Cardiol. pmid:25857917
Véricel E et al. Moderate oral supplementation with docosahexaenoic acid improves platelet function and oxidative stress in type 2 diabetic patients. 2015 Thromb. Haemost. pmid:25832443
Khanna V et al. Does the response to aspirin and clopidogrel vary over 6 months in patients with ischemic heart disease? 2015 J. Thromb. Haemost. pmid:25809653
Voon PT et al. Virgin olive oil, palm olein and coconut oil diets do not raise cell adhesion molecules and thrombogenicity indices in healthy Malaysian adults. 2015 Eur J Clin Nutr pmid:25804278
Karamouzis I et al. Enhanced oxidative stress and platelet activation in patients with Cushing's syndrome. 2015 Clin. Endocrinol. (Oxf) pmid:24923553
Willenberg I et al. Determining cyclooxygenase-2 activity in three different test systems utilizing online-solid phase extraction-liquid chromatography-mass spectrometry for parallel quantification of prostaglandin E(2), D(2) and thromboxane B(2). 2015 J Chromatogr A pmid:25777050
Wang J et al. Prevention of atherosclerosis by Yindan Xinnaotong capsule combined with swimming in rats. 2015 BMC Complement Altern Med pmid:25886942
Hill TL et al. The effect of tramadol and indomethacin coadministration on gastric barrier function in dogs. 2014 May-Jun J. Vet. Intern. Med. pmid:24684670