Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Dyslipidemias D050171 7 associated lipids
Pregnancy Complications D011248 19 associated lipids
Angina Pectoris, Variant D000788 3 associated lipids
Cat Diseases D002371 12 associated lipids
Ductus Arteriosus, Patent D004374 5 associated lipids
Biliary Tract Neoplasms D001661 7 associated lipids
Weight Loss D015431 56 associated lipids
Endotoxemia D019446 27 associated lipids
Tooth, Impacted D014095 9 associated lipids
Blister D001768 16 associated lipids
Adenomatous Polyposis Coli D011125 16 associated lipids
Death, Sudden, Cardiac D016757 12 associated lipids
Granulomatosis with Polyangiitis D014890 5 associated lipids
Lupus Nephritis D008181 8 associated lipids
Pancreatitis, Acute Necrotizing D019283 18 associated lipids
Obesity, Morbid D009767 8 associated lipids
Ventricular Remodeling D020257 28 associated lipids
Weil Disease D014895 2 associated lipids
Hypoxia-Ischemia, Brain D020925 22 associated lipids
Sneezing D012912 6 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

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Authors Title Published Journal PubMed Link
Steib CJ et al. Functional relevance of the cannabinoid receptor 2 - heme oxygenase pathway: a novel target for the attenuation of portal hypertension. 2013 Life Sci. pmid:24007798
DeFilippis AP et al. Thromboxane A(2) generation, in the absence of platelet COX-1 activity, in patients with and without atherothrombotic myocardial infarction. 2013 Circ. J. pmid:23985963
Siennicka A et al. Haemostatic factors and intraluminal thrombus thickness in abdominal aortic aneurysm. Is secondary fibrinolysis relevant? 2013 J. Physiol. Pharmacol. pmid:23959729
Kleinbongard P et al. Aspirate from human stented native coronary arteries vs. saphenous vein grafts: more endothelin but less particulate debris. 2013 Am. J. Physiol. Heart Circ. Physiol. pmid:23934849
Chen LB et al. [Coagulation and prothrombotic state parameters: clinical analysis in early pregnancy]. 2013 Zhonghua Yi Xue Za Zhi pmid:24284247
Santilli F et al. Effects of high-amount-high-intensity exercise on in vivo platelet activation: modulation by lipid peroxidation and AGE/RAGE axis. 2013 Thromb. Haemost. pmid:24030807
Kapłon-Cieślicka A et al. Predictors of high platelet reactivity during aspirin treatment in patients with type 2 diabetes. 2013 Kardiol Pol pmid:24065375
Jastrzębska M et al. Factors influencing multiplate whole blood impedance platelet aggregometry measurements, during aspirin treatment in acute ischemic stroke: a pilot study. 2013 Blood Coagul. Fibrinolysis pmid:24071649
Sun Y et al. Yeast exposure in the preparation of steamed rehmannia root improving its effects on alloxan-induced diabetic rats. 2013 J Ethnopharmacol pmid:24041459
d'Emmanuele di Villa Bianca R et al. Hydrogen sulphide pathway contributes to the enhanced human platelet aggregation in hyperhomocysteinemia. 2013 Proc. Natl. Acad. Sci. U.S.A. pmid:24019484
Reyes JJ et al. Antiplatelet effect of new lipophilic hydroxytyrosol alkyl ether derivatives in human blood. 2013 Eur J Nutr pmid:22584413
McMahon GS et al. Transient heparin-induced platelet activation linked to generation of platelet 12-lipoxygenase. Findings from a randomised controlled trial. 2013 Thromb. Haemost. pmid:23494053
Dharmasaroja PA et al. Aspirin nonresponders in patients with ischaemic stroke. 2013 Blood Coagul. Fibrinolysis pmid:23429255
Shiraishi M et al. Cholesterol enrichment of rabbit platelets enhances the Ca(2+) entry pathway induced by platelet-derived secondary feedback agonists. 2013 Life Sci. pmid:23499558
Larsen SB et al. Reduced antiplatelet effect of aspirin is associated with low-grade inflammation in patients with coronary artery disease. 2013 Thromb. Haemost. pmid:23407706
Fox T et al. Dysregulated heme oxygenase-ferritin system in pterygium pathogenesis. 2013 Cornea pmid:23792437
Borst O et al. Skepinone-L, a novel potent and highly selective inhibitor of p38 MAP kinase, effectively impairs platelet activation and thrombus formation. 2013 Cell. Physiol. Biochem. pmid:23817201
Zhang J et al. Effects of an aqueous extract of Crataegus pinnatifida Bge. var. major N.E.Br. fruit on experimental atherosclerosis in rats. 2013 J Ethnopharmacol pmid:23685195
Wei XJ et al. Effects of carboxymethylpachymaran on signal molecules in chicken immunocytes. 2013 Int. J. Biol. Macromol. pmid:23664932
Kang JW et al. Anti-platelet activity of erythro-(7S,8R)-7-acetoxy-3,4,3',5'-tetramethoxy-8-O-4'-neolignan from Myristica fragrans. 2013 Phytother Res pmid:23296979