Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Hypercholesterolemia D006937 91 associated lipids
Hyperlipoproteinemia Type II D006938 22 associated lipids
Hyperemia D006940 25 associated lipids
Hyperlipidemias D006949 73 associated lipids
Hyperlipoproteinemias D006951 15 associated lipids
Hyperlipoproteinemia Type IV D006953 6 associated lipids
Hypersensitivity D006967 22 associated lipids
Hypertension D006973 115 associated lipids
Hypertension, Portal D006975 12 associated lipids
Hypertension, Pulmonary D006976 32 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

Download all related citations
Per page 10 20 50 100 | Total 6367
Authors Title Published Journal PubMed Link
Lumley P et al. Maximal blockade of TxA2 without compromised PGI2 formation; a superior profile of the TxA2 receptor blocking drug GR32191 over aspirin. 1991 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:1825385
Patrono C et al. Thromboxane-dependent platelet activation as a transducer of enhanced risk of coronary and cerebral thrombosis. 1991 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:1825389
Zhao Y et al. Thromboxane and leukotriene generation by mononuclearcytes from cardiac transplant patients. 1991 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:1825392
Vial JH et al. Rebound elevation in urinary thromboxane B2 and 6-keto-PGF1 alpha excretion after aspirin withdrawal. 1991 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:1825534
Koshihara Y and Fukuda M Appearance of metabolic activities for arachidonate during development of mouse embryos. 1989 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:2526512
Fuse I and Tai HH Regulation of arachidonate release by G-proteins and protein kinase C in human platelets. 1989 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:2526540
Houtz P and Tai HH Enzyme immunoassay of thromboxane B2 using immobilized hapten and enzyme amplification. 1989 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:2526560
Hayashi Y et al. Radioimmunoassay of 11-dehydro-thromboxane B2 using monoclonal antibody. 1989 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:2526561
Knospe J et al. Derivatization of prostaglandins to corresponding anilides and analysis by HPLC. 1989 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:2526562
De Caterina R et al. Characteristics of thromboxane production by the isolated-perfused rat heart. 1987 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:2959082
Samhoun MN et al. Differential effect of vasoactive intestinal peptide on contractions induced by leukotriene D4, histamine, and acetylcholine in guinea pig lung parenchyma in vitro. 1987 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:2960144
Granström E and Kumlin M Assay of thromboxane production in biological systems: reliability of TXB2 versus 11-dehydro-TXB2 as targets for measurement. 1987 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:2960161
Lecompte T et al. Radioimmunoassay for 11-dehydro-thromboxane B2 using an iodinated ligand: preliminary applications to human fluids. 1987 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:2960162
Catella F et al. Analysis of multiple thromboxane metabolites in plasma and urine. 1987 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:2960166
Alessandrini P et al. Eicosanoid biosynthesis in human diabetes mellitus. 1987 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:2960175
Miyazaki H et al. Microdetermination of prostaglandins and thromboxane B2 by gas chromatography/high-resolution selected-ion monitoring. 1985 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:2936139
Kobayashi N et al. Effect of changes in prostaglandin synthesis by platelets and vessel wall on the formation of arterial thrombosis in rabbits. 1985 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:2936159
Nishikawa K et al. (E)-7-Phenyl-7-(3-pyridyl)-6-heptenoic acid (CV-4151): a potent, specific thromboxane A2 synthetase inhibitor. 1985 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:2936160
Westwick J et al. Inhibition of thromboxane formation prevents endotoxin-induced renal fibrin deposition in jaundiced rats. 1983 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:6221642
Kangasaho M et al. Formation of thromboxane B2 by platelets and concentrations of thromboxane B2 and 6-keto-prostaglandin F1 alpha in plasma after acute ethanol ingestion. 1983 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:6303086