Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Leiomyosarcoma D007890 4 associated lipids
Thromboangiitis Obliterans D013919 4 associated lipids
Embolism, Fat D004620 4 associated lipids
Bronchopulmonary Dysplasia D001997 4 associated lipids
Thrombasthenia D013915 4 associated lipids
Menorrhagia D008595 4 associated lipids
Systemic Inflammatory Response Syndrome D018746 4 associated lipids
Diseases in Twins D004200 4 associated lipids
Glomerulosclerosis, Focal Segmental D005923 4 associated lipids
Hyperaldosteronism D006929 4 associated lipids
Chediak-Higashi Syndrome D002609 4 associated lipids
Chest Pain D002637 4 associated lipids
Platelet Storage Pool Deficiency D010981 3 associated lipids
Takayasu Arteritis D013625 3 associated lipids
Tachycardia, Supraventricular D013617 3 associated lipids
Pneumonia, Aspiration D011015 3 associated lipids
Infertility D007246 3 associated lipids
Macular Edema D008269 3 associated lipids
Hydatidiform Mole D006828 3 associated lipids
Yang Deficiency D016711 3 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

Download all related citations
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Authors Title Published Journal PubMed Link
Honma S et al. Amelioration of cisplatin-induced mouse renal lesions by a cyclooxygenase (COX)-2 selective inhibitor. 2013 Eur. J. Pharmacol. pmid:23747596
Lee JJ et al. Antithrombotic and antiplatelet activities of Soshiho-tang extract. 2013 BMC Complement Altern Med pmid:23773779
Hau CS et al. Suppressive effects of antimycotics on thymic stromal lymphopoietin production in human keratinocytes. 2013 J. Dermatol. Sci. pmid:23688403
An J et al. Blocking of thromboxane Aâ‚‚ receptor attenuates airway mucus hyperproduction induced by cigarette smoke. 2013 Eur. J. Pharmacol. pmid:23399768
Brose SA and Golovko MY Eicosanoid post-mortem induction in kidney tissue is prevented by microwave irradiation. 2013 Prostaglandins Leukot. Essent. Fatty Acids pmid:24113545
Matsunobu T et al. Thromboxane A synthase-independent production of 12-hydroxyheptadecatrienoic acid, a BLT2 ligand. 2013 J. Lipid Res. pmid:24009185
Reese EA et al. Gabapentin's minimal action on markers of rat brain arachidonic acid metabolism agrees with its inefficacy against bipolar disorder. 2012 Aug-Sep Prostaglandins Leukot. Essent. Fatty Acids pmid:22841517
Chen CY et al. Functional analysis of human thromboxane synthase polymorphic variants. 2012 Pharmacogenet. Genomics pmid:22735388
Pelligand L et al. Pharmacokinetic/pharmacodynamic modelling of robenacoxib in a feline tissue cage model of inflammation. 2012 J. Vet. Pharmacol. Ther. pmid:21767277
Wenzel F et al. Determination of thromboxane formation, soluble CD40L release and thrombopoietin clearance in apheresis platelet concentrates. 2012 Platelets pmid:21806498
Tong Z et al. Influence of ShuJinHuoXue tablets on ischemia reperfusion injury of animals' skeletal muscle. 2012 Molecules pmid:22801363
Dragani A et al. Oxidative stress and platelet activation in subjects with moderate hyperhomocysteinaemia due to MTHFR 677 C→T polymorphism. 2012 Thromb. Haemost. pmid:22782530
Saito Y et al. Disruption of group IVA cytosolic phospholipase A(2) attenuates myocardial ischemia-reperfusion injury partly through inhibition of TNF-α-mediated pathway. 2012 Am. J. Physiol. Heart Circ. Physiol. pmid:22427514
Smith JP et al. Suboptimal inhibition of platelet cyclooxygenase-1 by aspirin in metabolic syndrome. 2012 Hypertension pmid:22311905
Brivio I et al. The pulmonary pharmacology of [4-methoxy-N1-(4-trans-nitrooxycyclohexyl)-N3-(3-pyridinylmethyl)-1,3-benzenedicarboxamide] (2NTX-99), an anti-atherotrombotic compound with therapeutic potential in pathological conditions that target lung vasculature. 2012 Prostaglandins Other Lipid Mediat. pmid:22342851
Lemkes BA et al. The influence of aspirin dose and glycemic control on platelet inhibition in patients with type 2 diabetes mellitus. 2012 J. Thromb. Haemost. pmid:22252020
Matsuzawa S et al. Ibudilast, a phosphodiesterase inhibitor, in combination with low-dose aspirin potently inhibits guinea pig carotid artery thrombosis without extending bleeding time and causing gastric mucosal injury. 2012 Arzneimittelforschung pmid:22945770
Sadilkova L et al. The purification step is not crucial in EIA measurements of thromboxane B2 and 11-dehydrothromboxane B2 in human plasma. 2012 Clin. Lab. pmid:22372363
Ju HK et al. Metabolomic investigation of the anti-platelet aggregation activity of ginsenoside Rk₁ reveals attenuated 12-HETE production. 2012 J. Proteome Res. pmid:22873173
Chandrasekaran CV et al. In vitro comparative evaluation of non-leaves and leaves extracts of Andrographis paniculata on modulation of inflammatory mediators. 2012 Antiinflamm Antiallergy Agents Med Chem pmid:22882083