Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Xing X and Xia S | Injury of liver sinusoidal endothelial cells in isolated liver perfusion model for regional chemotherapy in rats. | 1998 | Chin. Med. J. | pmid:10374437 |
Mao E et al. | [Pancreatic ischemia: a continuous injury factor in acute necrotic pancreatitis]. | 1997 | Zhonghua Wai Ke Za Zhi | pmid:10374521 |
Ren YJ et al. | Inhibitory effects of nimodipine on platelet aggregation and thrombosis. | 1998 | Zhongguo Yao Li Xue Bao | pmid:10374642 |
Shan CW et al. | Inhibitory effects of procainamide on rabbit platelet aggregation and thromboxane B2 production in vitro. | 1998 | Zhongguo Yao Li Xue Bao | pmid:10374644 |
Tong H et al. | Prostaglandin endoperoxide synthase-2 abundance is increased in brain tissues of late-gestation fetal sheep in response to cerebral hypoperfusion. | 1999 May-Jun | J. Soc. Gynecol. Investig. | pmid:10376268 |
Praticó D et al. | Iron-dependent human platelet activation and hydroxyl radical formation: involvement of protein kinase C. | 1999 | Circulation | pmid:10377074 |
Carvalho C et al. | A rat model presenting eosinophilia in the airways, lung eosinophil activation, and pulmonary hyperreactivity. | 1999 | Exp. Lung Res. | pmid:10378102 |
Tanaka H et al. | Leukotriene (LT)-receptor antagonist is more effective in asthmatic patients with a low baseline ratio of urinary LTE4 to 2,3-dinor-6-keto-prostaglandin (PG)F1alpha. | 1999 | Allergy | pmid:10380781 |
Walsh SW et al. | AA-2414, an antioxidant and thromboxane receptor blocker, completely inhibits peroxide-induced vasoconstriction in the human placenta. | 1999 | J. Pharmacol. Exp. Ther. | pmid:10381779 |
Panara MR et al. | Dose-dependent inhibition of platelet cyclooxygenase-1 and monocyte cyclooxygenase-2 by meloxicam in healthy subjects. | 1999 | J. Pharmacol. Exp. Ther. | pmid:10381787 |