Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

Cross Reference

Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Vitamin E Deficiency D014811 29 associated lipids
Hypertension, Renal D006977 9 associated lipids
Tachycardia D013610 7 associated lipids
Leukemia, Lymphoid D007945 18 associated lipids
Carbon Monoxide Poisoning D002249 9 associated lipids
Neutropenia D009503 15 associated lipids
Meningioma D008579 11 associated lipids
Lung Diseases, Obstructive D008173 10 associated lipids
Retinal Diseases D012164 4 associated lipids
Arthritis, Juvenile D001171 8 associated lipids
Per page 10 20 50 100 | Total 293

PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

Download all related citations
Per page 10 20 50 100 | Total 6367
Authors Title Published Journal PubMed Link
Clark KE et al. Effect of bisenoic prostaglandins and arachidonic acid on the uterine vasculature of pregnant sheep. 1982 Am. J. Obstet. Gynecol. pmid:7065014
Schuette AH et al. Effect of lung thromboxane generation on regional blood flow during sheep bypass. 1982 Am. J. Physiol. pmid:7065206
Mäkilä UM et al. Regulation of prostacyclin and thromboxane production by human umbilical vessels: the effect of estradiol and progesterone in a superfusion model. 1982 Prostaglandins Leukot Med pmid:7043492
Han P et al. Inhibition of platelet function of antiarrhythmic drugs, verapamil and disopyramide. 1982 Thromb. Haemost. pmid:7101234
Krausz MM et al. Adverse effects of prostacyclin used to perfuse isolated lung lobes. 1982 Am. J. Physiol. pmid:7044149
Hirsh PD et al. Influence of blood sampling site and technique on thromboxane concentrations in patients with ischemic heart disease. 1982 Am. Heart J. pmid:7102506
Siess W et al. Plasma catecholamines, platelet aggregation and associated thromboxane formation after physical exercise, smoking or norepinephrine infusion. 1982 Circulation pmid:7044612
Chierchia S et al. Failure of thromboxane A2 blockade to prevent attacks of vasospastic angina. 1982 Circulation pmid:7116586
Sasagawa S et al. Effects of thromboxane A2 injection on the rabbit coronary artery. I. Physiologic effects in healthy animals. 1982 Exp. Mol. Pathol. pmid:7117494
Socini A et al. Effects of the coumarin derivative AD6 on platelet aggregation, platelet vessel wall interactions and 6 keto PGF1 alpha production in perfused aortas, in experimentally hypercholesterolaemic rabbits. 1982 Pharmacol Res Commun pmid:7048340
Fantone JC et al. Inhibition of vascular permeability changes in rats by captopril. 1982 J. Clin. Invest. pmid:6282931
Ylikorkala O and Viinikka L Effect of amnioscopy on concentrations of prostaglandin F2 alpha, prostacyclin and thromboxane in maternal plasma. 1982 Gynecol. Obstet. Invest. pmid:6954125
Simpson RM et al. Generation of thromboxane A2 and aorta-contracting activity from platelets stimulated with modified C-reactive protein. 1982 Immunology pmid:7118160
Leach CM and Thorburn GD A comparative study of collagen induced thromboxane release from platelets of different species: implications for human atherosclerosis models. 1982 Prostaglandins pmid:7122912
Fletcher MS et al. Endotoxin, prostaglandins and renal fibrin deposition in obstructive jaundice. 1982 Br J Surg pmid:6751458
Shaw JO and Lyons RM Requirement for different Ca2+ pools in the activation of rabbit platelets II. Phospholipase activity. 1982 Biochim. Biophys. Acta pmid:6800410
Dejana E et al. Bleeding time in rats: a comparison of different experimental conditions. 1982 Thromb. Haemost. pmid:6753230
Addonizio VP et al. Inhibition of human platelet function by verapamil. 1982 Thromb. Res. pmid:7164035
Strano A et al. Platelet sensitivity to prostacyclin and thromboxane production in hyperlipidemic patients. 1982 Thromb. Haemost. pmid:6753232
Vargaftig BB et al. Adrenaline and PAF-acether synergize to trigger cyclooxygenase-independent activation of plasma-free human platelets. 1982 Thromb. Res. pmid:7164036
Flynn JT and Demling RH Inhibition of endogenous thromboxane synthesis by exogenous prostacyclin during endotoxemia in conscious sheep. 1982 Adv Shock Res pmid:6753534
Vlodavsky I et al. Platelet interaction with the extracellular matrix produced by cultured endothelial cells: a model to study the thrombogenicity of isolated subendothelial basal lamina. 1982 Thromb. Res. pmid:7179215
Smith MC et al. Prostacyclin substitution for heparin in long-term hemodialysis. 1982 Am. J. Med. pmid:6753575
Deby-Dupont G et al. Release of thromboxane B2 during adult respiratory distress syndrome and its inhibition by non steroidal anti-inflammatory substances in man. 1982 Arch Int Pharmacodyn Ther pmid:7181589
Zipser RD and Martin K Urinary excretion of arterial blood prostaglandins and thromboxanes in man. 1982 Am. J. Physiol. pmid:6950668
Ylikorkala O et al. Prostacyclin and thromboxane in chronic uremia: effect of hemodialysis. 1982 Clin. Nephrol. pmid:6754193
Shohami E et al. [Thromboxane in rat brain following incomplete ischemia]. 1982 Harefuah pmid:7182317
Hamasaki Y et al. Hypoxia stimulates prostacyclin generation by dog lung in vitro. 1982 Prostaglandins Leukot Med pmid:7051045
Panganamala RV and Cornwell DG The effects of vitamin E on arachidonic acid metabolism. 1982 Ann. N. Y. Acad. Sci. pmid:6816121
Mitrovic D et al. The in vitro production of prostanoids by cultured bovine articular chondrocytes. 1982 Prostaglandins pmid:6801735
Watanabe T et al. Characterization of the biosynthetic pathway of prostaglandin D2 in human platelet-rich plasma. 1982 J. Biol. Chem. pmid:6816798
Krishnamurthi S et al. Effect of pyridoxal 5'-phosphate (PALP) on human platelet aggregation, dense granule release and thromboxane B2 generation--role of Schiff base formation. 1982 Thromb. Haemost. pmid:6891107
Hall ER et al. The reduction of platelet thrombi on damaged vessel wall by a thromboxane synthetase inhibitor in rabbits. 1982 Thromb. Res. pmid:6891109
Davì G et al. [Effects of flurbiprofen on the platelet function in patients with ischemic cardiopathy]. 1982 Cardiologia pmid:6892383
De Caterina R et al. [Effects of isosorbide dinitrate on platelet aggregation and production of thromboxane B2]. 1982 Cardiologia pmid:6892461
Di Minno G et al. Arachidonic acid induces human platelet-fibrin retraction: the role of platelet cyclic endoperoxides. 1982 Thromb. Res. pmid:6803385
Suehiro A et al. The role of platelet hyperfunction in thrombus formation in hyperlipidemia. 1982 Thromb. Res. pmid:6803387
Rock JA et al. Cul-de-sac fluid in women with endometriosis: fluid volume and prostanoid concentration during the proliferative phase of the cycle--days 8 to 12. 1982 Fertil. Steril. pmid:6953017
de Boer AC et al. Platelet release and thromboxane synthesis in symptomatic coronary artery disease. 1982 Circulation pmid:6212161
Mari D et al. Coagulation and platelet activation after retinal vein occlusions. 1982 Haemostasis pmid:6215293
de Clerck F et al. Inhibition of 5-hydroxytryptamine-induced and -amplified human platelet aggregation by ketanserin (R 41 468), a selective 5-HT2-receptor antagonist. 1982 Agents Actions pmid:6215842
Mehta P et al. Comparison of umbilical vein models for measurement of relative prostacyclin and thromboxane production. 1982 Prostaglandins pmid:6820165
Mehta J and Mehta P Effects of propranolol therapy on platelet release and prostaglandin generation in patients with coronary heart disease. 1982 Circulation pmid:6216027
Stuart MJ and Allen JB Arachidonic acid metabolism in the neonatal platelet. 1982 Pediatrics pmid:6804924
Nolan RD et al. The pericardium as a source of prostacyclin in the dog, ox and rat. 1982 Prostaglandins pmid:6820168
Koyama I et al. Release of 6-keto-prostaglandin F1 alpha and thromboxane B2 from mouse peritoneal macrophages during their adhesion and spreading on a glass surface. 1982 Prostaglandins pmid:6896924
Uderman HD et al. Attenuation of the development of hypertension in spontaneously hypertensive rats by the thromboxane synthetase inhibitor, 4'-(imidazol-1-yl) acetophenone. 1982 Prostaglandins pmid:6897296
Katsumata M et al. Diphenylhydantoin: an alternative ligand of a glucocorticoid receptor affecting prostaglandin generation in A/J mice. 1982 Science pmid:6897299
Mehta P et al. Thromboxane and prostacyclin generation by intact human vessels in response to balloon catheter trauma. 1982 Prostaglandins Leukot Med pmid:6217465
Koyama I et al. [Production of 6-keto-prostaglandin F1 alpha and thromboxane B2 in mouse peritoneal macrophages during preparation of the cells]. 1982 Yakugaku Zasshi pmid:6897423
Wilson L et al. Alterations in reproductive tissue prostaglandins E and F, 6-keto-prostaglandin F1 alpha and thromboxane B2 with gestational age in the rat. 1982 Biol. Reprod. pmid:6897617
Randall MJ and Wilding RI Acute arterial thrombosis in rabbits: reduced platelet accumulation after treatment with thromboxane synthetase inhibitor dazoxiben hydrochloride, (UK-37, 248-01). 1982 Thromb. Res. pmid:6897751
De Caterina R et al. [Effect of isosorbide dinitrate on platelet aggregation and production of thromboxane B2]. 1982 Cardiologia pmid:6927441
Davì G et al. [Effects of flurbiprofen on platelet function in patients with ischemic cardiomyopathy]. 1982 Cardiologia pmid:6927457
Whinnery MA et al. Thromboxane B2 and prostaglandin E2 in the rat kidney with unilateral ureteral obstruction. 1982 Am. J. Physiol. pmid:6950670
Hwang DH and Donovan J In vitro and in vivo effects of vitamin E on arachidonic acid metabolism in rat platelets. 1982 J. Nutr. pmid:6806455
McNamara DB et al. Prostaglandin endoperoxide metabolism by microsomes of whole kidneys from normal, congenital unilateral hydronephrotic and unilateral ureteral obstructed rats. 1982 Prostaglandins pmid:6962465
Lecompte T et al. Interference of transmethylation inhibitors with thromboxane synthesis in rat platelets. 1982 Biochem. Biophys. Res. Commun. pmid:6809005
Patrignani P et al. Selective cumulative inhibition of platelet thromboxane production by low-dose aspirin in healthy subjects. 1982 J. Clin. Invest. pmid:7045161
Bakhle YS and Zakrzewski JT Effects of the oestrous cycle on the metabolism of arachidonic acid in rat isolated lung. 1982 J. Physiol. (Lond.) pmid:6809935
Watkins WD et al. Thromboxane and pulmonary hypertension following E. coli endotoxin infusion in sheep: effect of an imidazole derivative. 1982 Prostaglandins pmid:7048422
Hüttemeier PC et al. Acute pulmonary hypertension and lung thromboxane release after endotoxin infusion in normal and leukopenic sheep. 1982 Circ. Res. pmid:7042108
Cerletti C et al. Non-steroidal anti-inflammatory drugs react with two sites on platelet cyclo-oxygenase. Evidence from "in vivo" drug interaction studies in rats. 1982 Biochim. Biophys. Acta pmid:6799004
Kunkel SL et al. Production of cyclooxygenase products and superoxide anion by macrophages in response to chemotactic factors. 1982 Prostaglandins pmid:6300969
Levy-Toledano S et al. Human platelet activation in the absence of aggregation: a calcium-dependent phenomenon independent of thromboxane formation. 1982 Blood pmid:6803854
Rettkowski W et al. Studies of the influence of nitroglycerin on the synthesis of prostaglandins and thromboxane A2 and on platelet aggregation. 1982 Arzneimittelforschung pmid:6805480
Panossian A et al. On the mechanism of biosynthesis of leukotrienes and related compounds. 1982 FEBS Lett. pmid:6297982
Michelassi F et al. Leukotriene D4: a potent coronary artery vasoconstrictor associated with impaired ventricular contraction. 1982 Science pmid:6808665
Pawlowski NA et al. Uptake and metabolism of monohydroxy-eicosatetraenoic acids by macrophages. 1982 J. Exp. Med. pmid:6951919
Nugent WC et al. Prostaglandin response to intravenous nitroglycerin. 1982 J. Surg. Res. pmid:6810023
Harada Y et al. Changes in the levels of prostaglandins and thromboxane and their roles in the accumulation of exudate in rat carrageenin-induced pleurisy--a profile analysis using gas chromatography-mass spectrometry. 1982 Prostaglandins pmid:6889754
Yoshimoto T and Yamamoto S Partial purification and assay of thromboxane A synthase from bovine platelets. 1982 Meth. Enzymol. pmid:6890138
Tai HH Assay of thromboxane A synthase inhibitors. 1982 Meth. Enzymol. pmid:6890139
Scherhag R et al. Dietary administration of eicosapentaenoic and linolenic acid increases arterial blood pressure and suppresses vascular prostacyclin synthesis in the rat. 1982 Prostaglandins pmid:6285420
Watkins WD et al. Thromboxane and prostacyclin changes during cardiopulmonary bypass with and without pulsatile flow. 1982 J. Thorac. Cardiovasc. Surg. pmid:6980332
Malemud CJ et al. Correlation of the biosynthesis of prostaglandin and cyclic AMP in monolayer cultures of rabbit articular chondrocytes. 1982 Biochim. Biophys. Acta pmid:6280776
Xiu RJ et al. Anisodamine inhibits thromboxane synthesis, granulocyte aggregation, and platelet aggregation. A possible mechanism for its efficacy in bacteremic shock. 1982 JAMA pmid:7057538
Kelton JG et al. Sex related differences in platelet function: the effect of aspirin. 1982 Blood pmid:7059670
Ylikorkala O et al. The effect of oral contraceptives on antiaggregatory prostacyclin and proaggregatory thromboxane A2 in humans. 1982 Am. J. Obstet. Gynecol. pmid:7036746
Kelton JG et al. Sex-related differences in the efficacy of acetylsalicylic acid (ASA) : the absorption of ASA and its effect on collagen-induced thromboxane B2 generation. 1981 Oct 1-15 Thromb. Res. pmid:7330835
Randall MJ et al. UK-37, 248, a novel, selective thromboxane synthetase inhibitor with platelet anti-aggregatory and anti-thrombotic activity. 1981 Jul 1-15 Thromb. Res. pmid:6795753
Tsuboi T et al. Effect of gliclazide on prostaglandin and thromboxane synthesis in guinea-pig platelets. 1981 Jan 1-15 Thromb. Res. pmid:7233394
Webb PJ et al. Do prostacyclin and thromboxane play a role in endotoxic shock? 1981 Br J Surg pmid:7025959
Parks WM et al. Comparative effect of ibuprofen on endothelial and platelet prostaglandin synthesis. 1981 J. Pharmacol. Exp. Ther. pmid:7026767
Roy AC et al. Effect of intravenous infusion of OKY-1581 (sodium-(E)-3-[4-(3-pyridylmethyl)phenyl] -2-methylacrylate) on circulatory thromboxane A2 and prostacyclin levels in anaesthetized baboon. 1981 Prostaglandins Med pmid:7029585
Dembélé-Duchesne MJ et al. Some new prospects in the mechanism of control of arachidonate metabolism in human placenta and amnion. 1981 Prostaglandins pmid:6801732
Cook JA et al. Sensitization of essential fatty acid-deficient rats to endotoxin by arachidonate pretreatment: role of thromboxane A2. 1981 Circ. Shock pmid:7237685
Lorenz R et al. Effects of very low versus standard dose acetyl salicylic acid, dipyridamole and sulfinpyrazone on platelet function and thromboxane formation in man. 1981 Eur. J. Pharmacol. pmid:7238575
Polley MJ et al. Human complement in the arachidonic acid transformation pathway in platelets. 1981 J. Exp. Med. pmid:7241047
Mahoney DA et al. Urinary thromboxane B2 on allograft rejection. 1981 Lancet pmid:6118500
Allen JB et al. Irradiation decreases vascular prostacyclin formation with no concomitant effect on platelet thromboxane production. 1981 Lancet pmid:6118629
Gilani SH and Persaud TV Embryopathic effects of thromboxane B2 in the chick. 1981 Prostaglandins Med pmid:7267828
Anderson CB et al. Thromboxane-B2 and renovascular resistance during hypothermic pulsatile perfusion. 1981 Transplant. Proc. pmid:7268892
Coker SJ et al. Thromboxane and prostacyclin release from ischaemic myocardium in relation to arrhythmias. 1981 Nature pmid:6894485
Bishai I and Coceani F Transformations of prostaglandin H2 in the cat brain. 1981 Biochim. Biophys. Acta pmid:6894549
Seitz M et al. The influence of synovial fluid from patients with rheumatoid arthritis on the proliferation of peripheral blood lymphocytes and the prostanoid release from monocytes. 1981 Agents Actions pmid:7340450
Prancan A et al. Platelet thromboxane production during endotoxin shock. 1981 Agents Actions pmid:7340458
Hwang DH Characteristics of the aggregation of platelets and the formation of prostaglandins (PGs) in rat. 1981 Prog. Lipid Res. pmid:7342108
Worthington RE and Nakeff A Thromboxane synthesis in megakaryocytes isolated by centrifugal elutriation. 1981 Blood pmid:6786393
Igarashi K et al. Effect of polyamines on prostaglandin synthesis in various cell-free systems. 1981 Biochem. Biophys. Res. Commun. pmid:6800368