Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

Cross Reference

Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Angina, Unstable D000789 14 associated lipids
Angina Pectoris, Variant D000788 3 associated lipids
Angina Pectoris D000787 27 associated lipids
Anemia, Sickle Cell D000755 34 associated lipids
Anemia D000740 21 associated lipids
Anaphylaxis D000707 35 associated lipids
Alcoholic Intoxication D000435 15 associated lipids
Albuminuria D000419 18 associated lipids
Airway Obstruction D000402 13 associated lipids
Agranulocytosis D000380 7 associated lipids
Adenocarcinoma D000230 166 associated lipids
Acidosis D000138 13 associated lipids
Abortion, Habitual D000026 5 associated lipids
Per page 10 20 50 100 | Total 293

PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

Download all related citations
Per page 10 20 50 100 | Total 6367
Authors Title Published Journal PubMed Link
Morita I et al. Characterization of thromboxane B2 and 6-ketoprostaglandin F alpha by combined gas chromatography and chemical-ionization mass spectrometry. 1978 J. Chromatogr. pmid:681479
Mitchell MD et al. Production of thromboxane B2 by intra-uterine tissues from pregnant goats in vitro. 1978 J. Endocrinol. pmid:681871
Anderson MW et al. Kinetic studies on the conversion of prostaglandin endoperoxide PGH2 by thromboxane synthase. 1978 Prostaglandins pmid:725086
Roberts LJ et al. Metabolism of thromboxane B2 in the monkey. 1978 J. Biol. Chem. pmid:97291
Hyman AL et al. Prostaglandins and the lung. 1978 Am. Rev. Respir. Dis. pmid:339796
Boura AL and Murphy RD Thromboxane B2 inhibits prostaglandin E2 inactivation by the rat isolated perfused lung. 1978 Jul-Aug Clin. Exp. Pharmacol. Physiol. pmid:699382
Ciabattoni G et al. Characterization of furosemide-induced activation of the renal prostaglandin system. 1979 Eur. J. Pharmacol. pmid:393525
Svensson J Structure and quantitative determination of the major urinary metabolite of thromboxane B2 in the guinea pig. 1979 Prostaglandins pmid:472333
Langs DA et al. Thromboxane molecules do not adopt the prostaglandin hairpin conformation. 1979 Nature pmid:481594
Jonsson CE et al. Prostaglandins and thromboxanes in burn injury in man. 1979 Scand J Plast Reconstr Surg pmid:451477
Bailey JM et al. Anti-inflammatory drugs in experimental atherosclerosis. Part 4. Inhibition of atherosclerosis in vivo and thromboxane synthesis and platelet aggregation in vitro. 1979 Atherosclerosis pmid:454516
Taylor L et al. Prostaglandin production by type II alveolar epithelial cells. 1979 Biochim. Biophys. Acta pmid:435506
Folkert VW and Schlondorff D Prostaglandin synthesis in isolated glomeruli. 1979 Prostaglandins pmid:441427
Parker CW et al. Formation of thromboxane B2 and hydroxyarachidonic acids in purified human lymphocytes in the presence and absence of PHA. 1979 J. Immunol. pmid:448099
Needleman P et al. Platelet and blood vessel arachidonate metabolism and interactions. 1979 J. Clin. Invest. pmid:372240
Morley J et al. Prostaglandin and thromboxane production by human and guinea-pig macrophages and leucocytes. 1979 Prostaglandins pmid:493559
Meyers KM et al. A dominant role of thromboxane formation in secondary aggregation of platelets. 1979 Nature pmid:503210
de Deckere EA et al. Influence of type of dietary fat on the prostaglandin release from isolated rabbit and rat hearts and from rat aortas. 1979 Prostaglandins pmid:504696
Powell WS Metabolism of prostaglandins, prostaglandin analogs and thromboxane B2 by lung and liver microsomes from pregnant rabbits. 1979 Biochim. Biophys. Acta pmid:518891
Spagnuolo C et al. Differential effects of probenecid on the levels of endogenous PGF2 alpha and TXB2 in brain cortex. 1979 Prostaglandins pmid:523683
Bennett A and Sanger GJ Trimethoquinol selectively antagonises longitudinal muscle contractions of rat isolated gastric fundus to thromboxane B2 and epoxymethano analogues of PGH2 [proceedings]. 1979 Br. J. Pharmacol. pmid:526738
Prancan AV et al. L8027 and 1-nonyl-imidazole as non-selective inhibitors of thromboxane synthesis. 1979 Eur. J. Pharmacol. pmid:527664
Makheja AN et al. Effects of onion (Allium cepa) extract on platelet aggregation and thromboxane synthesis. 1979 Prostaglandins Med pmid:552092
Lefer AM et al. Protective effects of a novel thromboxane analog in lethal traumatic shock. 1979 Prostaglandins Med pmid:552102
Russell NH et al. Thrombocytopathy in preleukaemia: association with a defect of thromboxane A2 activity. 1979 Br. J. Haematol. pmid:570847
Anhut H et al. Prostaglandin D2 is the prevailing prostaglandin in the acute inflammatory exudate of urate arthritis in the chicken. 1979 Br. J. Pharmacol. pmid:570865
Lewy RI et al. Detection of thromboxane B2 in peripheral blood of patients with Prinzmetal's angina. 1979 Prostaglandins Med pmid:575861
Ohuchi K et al. Prostaglandins E2, F2 alpha, 6-keto-F1 alpha and thromboxane B2 levels in carrageenin-induced inflammatory exudates in the rat air-pouch granuloma. 1979 Prostaglandins Med pmid:583576
Daniel EE et al. Prostaglandins and myogenic control of tension in lower esophageal sphincter in vitro. 1979 Prostaglandins pmid:379920
Kanzaki Y et al. Thromboxane as possible trigger of liver regeneration. 1979 Cell Mol Biol Incl Cyto Enzymol pmid:535003
Russell FA and Deykin D The use of high pressure liquid chromatography (HPLC) for the separation of radiolabeled arachidonic acid and its metabolities produced by thrombin-treated human platelets. I. The validation of the technique. 1979 Prostaglandins pmid:523671
Roberts LJ et al. Prostaglandin thromboxane, and 12-hydroxy-5,8,10,14-eicosatetraenoic acid production by ionophore-stimulated rat serosal mast cells. 1979 Biochim. Biophys. Acta pmid:389290
Dutilh CE et al. Study of the two pathways for arachidonate oxygenation in blood platelets. 1979 Lipids pmid:34075
Kelly JP et al. Effect of inhibitors of arachidonic acid metabolism on mitogenesis in human lymphocytes: possible role of thromboxanes and products of the lipoxygenase pathway. 1979 J. Immunol. pmid:109510
Whittle BJ Prostaglandin synthetase inhibitors. Drugs which affect arachidonic acid metabolism. 1979 Acta Obstet Gynecol Scand Suppl pmid:111464
Robinson JS et al. Prostaglandin E, thromboxane B2 and 6-oxo-prostaglandin F1 alpha in amniotic fluid and maternal plasma of rhesus monkeys (Macaca mulatta) during the latter third of gestation. 1979 J. Endocrinol. pmid:112214
Burch RM et al. Vasopressin stimulates thromboxane synthesis in the toad urinary bladder: effects of imidazole. 1979 J. Pharmacol. Exp. Ther. pmid:113526
Patrono C et al. Inhibition of platelet cyclooxygenase by aspirin-like drugs: methods for in vitro and ex vivo assessment. 1979 Agents Actions Suppl. pmid:115255
Wong PY and Cheung WY Calmodulin stimulates human platelet phospholipase A2. 1979 Biochem. Biophys. Res. Commun. pmid:116656
Okuma M and Uchino H Altered arachidonate metabolism by platelets in patients with myeloproliferative disorders. 1979 Blood pmid:116695
Best LC et al. Evidence that extracellular calcium ions inhibit thromboxane B2 biosynthesis by human platelets. 1979 Biochem. Biophys. Res. Commun. pmid:117802
Jarabak J and Fried J Comparison of substrate specificities of the human placental NAD- and NADP-linked 15-hydroxyprostaglandin dehydrogenases. 1979 Prostaglandins pmid:42948
Miura Y and Fukui N Prostaglandins as possible triggers for liver regeneration after partial hepatectomy. A review. 1979 Cell Mol Biol Incl Cyto Enzymol pmid:44483
Ford-Hutchinson AW et al. The aggregation of rat neutrophils by arachidonic acid: a possible bioassay for lipoxygenase activity. 1979 J. Pharm. Pharmacol. pmid:43380
Dembińska-Kièć A et al. Prostacyclin-dependent differences in TXA2 formation by platelets from normal and atherosclerotic rabbits. 1979 Atherosclerosis pmid:224890
Hassid A et al. Prostaglandin synthesis in isolated rat kidney glomeruli. 1979 Proc. Natl. Acad. Sci. U.S.A. pmid:286300
Le Breton GC et al. 13-Azaprostanoic acid: a specific antagonist of the human blood platelet thromboxane/endoperoxide receptor. 1979 Proc. Natl. Acad. Sci. U.S.A. pmid:291066
Chignard M et al. Arachidonate-mediated bronchoconstriction and platelet activation are inhibited by microgram doses of compound L8027 which are not selective for thromboxane synthetase. 1979 Agents Actions Suppl. pmid:291306
Peskar BA and Holland A Plasma levels of immunoreactive 15-keto-13,14-dihydro-thromboxane B2 in guinea pigs during anaphylaxis and after histamine injection. 1979 Agents Actions Suppl. pmid:294148
Kass MA and Holmberg NJ Prostaglandin and thromboxane synthesis by microsomes of rabbit ocular tissues. 1979 Invest. Ophthalmol. Vis. Sci. pmid:761971