Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

Cross Reference

Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Hyperlipoproteinemias D006951 15 associated lipids
Coronary Vasospasm D003329 9 associated lipids
Scleroderma, Systemic D012595 16 associated lipids
Keratitis D007634 7 associated lipids
Mastitis, Bovine D008414 8 associated lipids
Celiac Disease D002446 16 associated lipids
Rhinitis, Allergic, Seasonal D006255 7 associated lipids
Placenta Diseases D010922 5 associated lipids
Salmonella Infections, Animal D012481 9 associated lipids
Raynaud Disease D011928 7 associated lipids
Per page 10 20 50 100 | Total 293

PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

Download all related citations
Per page 10 20 50 100 | Total 6367
Authors Title Published Journal PubMed Link
Mäkilä UM et al. Regulation of prostacyclin and thromboxane production by human umbilical vessels: the effect of estradiol and progesterone in a superfusion model. 1982 Prostaglandins Leukot Med pmid:7043492
Krausz MM et al. Adverse effects of prostacyclin used to perfuse isolated lung lobes. 1982 Am. J. Physiol. pmid:7044149
Hirsh PD et al. Influence of blood sampling site and technique on thromboxane concentrations in patients with ischemic heart disease. 1982 Am. Heart J. pmid:7102506
Siess W et al. Plasma catecholamines, platelet aggregation and associated thromboxane formation after physical exercise, smoking or norepinephrine infusion. 1982 Circulation pmid:7044612
Chierchia S et al. Failure of thromboxane A2 blockade to prevent attacks of vasospastic angina. 1982 Circulation pmid:7116586
Sasagawa S et al. Effects of thromboxane A2 injection on the rabbit coronary artery. I. Physiologic effects in healthy animals. 1982 Exp. Mol. Pathol. pmid:7117494
Socini A et al. Effects of the coumarin derivative AD6 on platelet aggregation, platelet vessel wall interactions and 6 keto PGF1 alpha production in perfused aortas, in experimentally hypercholesterolaemic rabbits. 1982 Pharmacol Res Commun pmid:7048340
Simpson RM et al. Generation of thromboxane A2 and aorta-contracting activity from platelets stimulated with modified C-reactive protein. 1982 Immunology pmid:7118160
Leach CM and Thorburn GD A comparative study of collagen induced thromboxane release from platelets of different species: implications for human atherosclerosis models. 1982 Prostaglandins pmid:7122912
Bottoms GD et al. Thromboxane, prostaglandin I2 (epoprostenol), and the hemodynamic changes in equine endotoxin shock. 1982 Am. J. Vet. Res. pmid:7049018
Poubelle P et al. [Mononucleated phagocytes from rheumatoid synovial fluid. Synthesis of prostanoids and first pharmacological applications]. 1982 Rev Rhum Mal Osteoartic pmid:7123126
Homma T and Malik KU Effect of prostaglandins on pancreatic circulation in anesthetized dogs. 1982 J. Pharmacol. Exp. Ther. pmid:7050343
Bradlow BA and Chetty N Dosage frequency for suppression of platelet function by low dose aspirin therapy. 1982 Thromb. Res. pmid:7123514
Buchanan MR et al. Aspirin inhibits platelet function independent of the acetylation of cyclo-oxygenase. 1982 Thromb. Res. pmid:7071811
Tremoli E et al. Metformin reduces platelet hypersensitivity in hypercholesterolemic rabbits. 1982 Atherosclerosis pmid:7073794
Martin JF et al. Effect of acetylsalicylic acid on platelet aggregation and thromboxane B2 production in flowing aortic blood in the rat studied with a filter loop technique. 1982 Thromb. Res. pmid:6814004
Dorsch W et al. Mediator studies in skin blister fluid from patients with dual skin reactions after intradermal allergen injection. 1982 J. Allergy Clin. Immunol. pmid:6181112
Numano F et al. Effects of thromboxane A2 injection on the rabbit coronary artery. II. The production of infarcts in cholesterol-fed animals. 1982 Exp. Mol. Pathol. pmid:6956517
Ylikorkala O et al. Production of prostacyclin and thromboxane during cesarean section. 1982 Obstet Gynecol pmid:6755324
Utsunomiya T et al. Modification of inflammatory response to aspiration with ibuprofen. 1982 Am. J. Physiol. pmid:6756172
Goldsmith JC and Needleman SW A comparative study of thromboxane and prostacyclin release from ex vivo and cultured bovine vascular endothelium. 1982 Prostaglandins pmid:6815717
Chong BH et al. Heparin-induced thrombocytopenia: association of thrombotic complications with heparin-dependent IgG antibody that induces thromboxane synthesis in platelet aggregation. 1982 Lancet pmid:6128550
Ody C et al. 6-Ketoprostaglandin F1 alpha, prostaglandins E2, F2 alpha and thromboxane B2 production by endothelial cells, smooth muscle cells and fibroblasts cultured from piglet aorta. 1982 Biochim. Biophys. Acta pmid:6214281
Rock JA et al. Cul-de-sac fluid in women with endometriosis: fluid volume and prostanoid concentration during the proliferative phase of the cycle--days 8 to 12. 1982 Fertil. Steril. pmid:6953017
Whinnery MA et al. Thromboxane B2 and prostaglandin E2 in the rat kidney with unilateral ureteral obstruction. 1982 Am. J. Physiol. pmid:6950670
Meydani SN and Dupont J Effect of zinc deficiency on prostaglandin synthesis in different organs of the rat. 1982 J. Nutr. pmid:7045297
Srivastava KC and Awasthi KK A comparative study on the effect of cis (oleic, linoleic) and trans (elaidic, linoelaidic) fatty acids on the in vitro prostaglandin biosynthesis in human blood platelets from (1-14C) arachidonic acid. 1982 Prostaglandins Leukot Med pmid:6818563
Dore-Duffy P Differential effect of prostaglandins and other products of arachidonic acid metabolism on measles virus replication in Vero cells. 1982 Prostaglandins Leukot Med pmid:6281810
Kelley VE et al. Effect of ibuprofen, a fatty acid cyclooxygenase inhibitor, on murine lupus. 1982 Clin. Immunol. Immunopathol. pmid:6819912
Miller OV et al. Acetyl glycerylphosphorylcholine inhibition of prostaglandin I2-stimulated adenosine 3',5'-cyclic monophosphate levels in human platelets. Evidence for thromboxane A2 dependence. 1982 Biochim. Biophys. Acta pmid:6285985
Landgraf-Leurs MM et al. Aggregation and thromboxane formation by platelets and vascular prostacyclin production from BB rats. An animal model for type I diabetes. 1982 Prostaglandins pmid:6812171
Miller JL et al. Arachidonic acid metabolism in guinea pig megakaryocytes. 1982 Biochem. Biophys. Res. Commun. pmid:6812584
Rothberg KG and Hitchcock M In vitro biosynthesis of cyclooxygenase metabolites in ovalbumin-sensitized and control lungs of guinea pigs. 1982 Biochem. Pharmacol. pmid:6812589
Ylikorkala O et al. The effect of oral contraceptives on antiaggregatory prostacyclin and proaggregatory thromboxane A2 in humans. 1982 Am. J. Obstet. Gynecol. pmid:7036746
Uyama O et al. Plasma concentrations of 6-keto-prostaglandin F1 alpha in patients with hypertension, cerebrovascular disease or Takayasu's arteritis. 1982 Jan 1-15 Thromb. Res. pmid:6121391
Sakai K et al. Roles of endogenous prostacyclin and thromboxane A2 in the ischemic canine heart. 1982 Jan-Feb J. Cardiovasc. Pharmacol. pmid:6176788
Giannessi D et al. Methodological assessment and applications of a radioimmunoassay for thromboxane (TxB2) to measurement of TxB2 release by platelets. 1982 Jan-Mar J. Nucl. Med. Allied Sci. pmid:7108634
Shohami E et al. The effect of incomplete cerebral ischemia on prostaglandin levels in rat brain. 1982 Jul-Aug Stroke pmid:6896589
Mest HJ et al. [Effect of stress on blood level of prostaglandins in students during exams]. 1982 May-Jun Farmakol Toksikol pmid:7095121
Simmons PM et al. The release of leukotriene B4 during experimental inflammation. 1983 Biochem. Pharmacol. pmid:6305369
Svensson J and Samuelsson K Inhibition of platelet function by low dose acetylsalicylic acid in patients with cerebrovascular disease. 1983 Thromb. Res. pmid:20218005
McManus LM et al. Thromboxane B2 (TxB2) release following acetyl glyceryl ether phosphorylcholine (AGEPC) infusion in the rabbit. 1983 Immunopharmacology pmid:6832960
Martin JL et al. Effect of atrial pacing on intracoronary thromboxane production in coronary artery disease. 1983 J. Am. Coll. Cardiol. pmid:6833660
Ferraris VA and Swanson E Aspirin usage and perioperative blood loss in patients undergoing unexpected operations. 1983 Surg Gynecol Obstet pmid:6836459
Margotat A et al. A rapid and simple assay for the study of thromboxane B2 synthesis by intact human platelets. 1983 J Pharmacol Methods pmid:6843139
Johnsen SA et al. Conversion of arachidonic acid in human maternal and neonatal mononuclear leukocytes. 1983 Immunol. Lett. pmid:6411611
Rotmensch HH et al. Plasma platelet products and exercise-induced myocardial ischemia. 1983 J. Lab. Clin. Med. pmid:6854135
Hamelin SS and Chan AC Modulation of platelet thromboxane and malonaldehyde by dietary vitamin E and linoleate. 1983 Lipids pmid:6855486
Menys VC and Davies JA Inhibitory effects of ZK 36374, a stable prostacyclin analogue, on adhesion of rabbit platelets to damaged aorta and serotonin release by adherent platelets. 1983 Clin. Sci. pmid:6190604
Hartung HP and Toyka KV Activation of macrophages by substance P: induction of oxidative burst and thromboxane release. 1983 Eur. J. Pharmacol. pmid:6191998
Tanganelli I et al. [Thromboxane, beta-thromboglobulin and the degree of blood sugar control in type 1 diabetes mellitus]. 1983 Boll. Soc. Ital. Biol. Sper. pmid:6194801
Capodicasa G et al. Platelet thromboxane formation and BTG levels after intensive charcoal HP in uremics or regular hemodialytic treatment (RHT). 1983 Int J Artif Organs pmid:6195116
Roth DM et al. Protective actions of ibuprofen in arachidonate-induced sudden death. 1983 Pharmacology pmid:6413987
Salmon JA et al. Synthesis of arachidonate cyclo-oxygenase products by rheumatoid and nonrheumatoid synovial lining in nonproliferative organ culture. 1983 Ann. Rheum. Dis. pmid:6402992
Harlan J et al. Selective inhibition of thromboxane synthesis during experimental endotoxemia in the goat: effects on pulmonary haemodynamics and lung lymph flow. 1983 Br J Clin Pharmacol pmid:6337602
Ball HA et al. Effect of dazoxiben, a specific inhibitor of thromboxane synthetase, on acute pulmonary responses to E. coli endotoxin in anaesthetized cats. 1983 Br J Clin Pharmacol pmid:6337603
Dodd NJ et al. Use of a thromboxane synthetase inhibitor, dazoxiben, during haemodialysis. 1983 Br J Clin Pharmacol pmid:6337605
Di Minno G et al. Exposure of platelet fibrinogen-binding sites by collagen, arachidonic acid, and ADP: inhibition by a monoclonal antibody to the glycoprotein IIb-IIIa complex. 1983 Blood pmid:6216929
Ylikorkala O et al. Maternal prostacyclin, thromboxane, and placental blood flow. 1983 Am. J. Obstet. Gynecol. pmid:6338724
Williams GA et al. Prostacyclin and thromboxane A2 derivatives in rhegmatogenous subretinal fluid. 1983 Arch. Ophthalmol. pmid:6338873
Ylikorkala O et al. Effect of vacuum curettage on the concentrations of plasma 6-keto-prostaglandin F1 alpha and serum thromboxane B2. 1983 Br J Obstet Gynaecol pmid:6338904
Marcella JJ et al. Exercise-induced myocardial ischemia in patients with coronary artery disease: lack of evidence for platelet activation or fibrin formation in peripheral venous blood. 1983 J. Am. Coll. Cardiol. pmid:6339591
Vlasses PH et al. Urinary excretion of prostacyclin and thromboxane A2 metabolites after angiotensin converting enzyme inhibition in hypertensive patients. 1983 Prostaglandins Leukot Med pmid:6308685
Huval WV et al. Thromboxane mediation of cardiovascular dysfunction following aspiration. 1983 Surgery pmid:6308843
Hartung HP Acetyl glyceryl ether phosphorylcholine (platelet-activating factor) mediates heightened metabolic activity in macrophages. Studies on PGE, TXB2 and O2- production, spreading, and the influence of calmodulin-inhibitor W-7. 1983 FEBS Lett. pmid:6309563
Sheng WY et al. Kinetic comparison and regulation of the cascade of microsomal enzymes involved in renal arachidonate and endoperoxide metabolism. 1983 J. Biol. Chem. pmid:6401732
Chetty N and Bradlow BA The effects of a vegetarian diet on platelet function and fatty acids. 1983 Thromb. Res. pmid:6612688
Parry MJ Effects of thromboxane synthetase inhibition on arachidonate metabolism and platelet behaviour. 1983 Br J Clin Pharmacol pmid:6401997
Ujiie A et al. [Studies on the inhibitory effect of etafenone hydrochloride on platelet aggregation]. 1983 Nippon Yakurigaku Zasshi pmid:6618341
Kawaguchi H Thromboxane synthesis in hypercholesterolemic platelets--on the mechanism of increased thromboxane synthesis. 1983 Hokkaido Igaku Zasshi pmid:6618425
Jakubowski JA et al. Arachidonic acid metabolism by platelets of differing size. 1983 Br. J. Haematol. pmid:6402003
Dubin NH et al. Thromboxane production in the pregnant rat: differential recovery by platelets and uterus following aspirin administration. 1983 Biol. Reprod. pmid:6626652
Sinzinger H and Firbas W [Cells of the vascular wall synthesize thromboxane]. 1983 Wien. Klin. Wochenschr. pmid:6369802
Mehta P et al. Inhibitory effects of diltiazem on platelet activation caused by ionophore A23187 plus ADP or epinephrine in subthreshold concentrations. 1983 J. Lab. Clin. Med. pmid:6411841
Gordon PR et al. Platelet arachidonate metabolism and platelet function in zinc-deficient rats. 1983 J. Nutr. pmid:6403678
Okegawa T et al. Endotoxin induces chronic prostaglandin and thromboxane synthesis from ureter-obstructed kidneys: role of inflammatory cells. 1983 J. Pharmacol. Exp. Ther. pmid:6403696
Westwick J et al. Platelet activation during steady state sickle cell disease. 1983 J Med pmid:6224876
Ellsworth ML et al. Pulmonary prostacyclin production with increased flow and sympathetic stimulation. 1983 J Appl Physiol Respir Environ Exerc Physiol pmid:6415017
Dahl ML et al. Sodium salicylate interferes with the inhibitory effects of aspirin and indomethacin on human platelets. 1983 Prostaglandins Leukot Med pmid:6415666
Han P et al. Verapamil and collagen-induced platelet reactions--evidence for a role for intracellular calcium in platelet activation. 1983 Thromb. Haemost. pmid:6415847
Fischer S et al. In vivo and in vitro effects of nafazatrom (Bay g 6575), an antithrombotic compound, on arachidonic acid metabolism in platelets and vascular tissue. 1983 Biochem. Pharmacol. pmid:6688182
Bailey IA et al. Effects of vascular trauma and transient myocardial ischaemia on coronary venous prostaglandin levels in the dog. 1983 Cardiovasc. Res. pmid:6688202
Srivastava KC and Awasthi KK Separation and quantitative determination of radiolabeled prostaglandins, thromboxanes, 6-keto-prostaglandin F1 alpha and other arachidonic acid metabolites produced in biological material. 1983 J. Chromatogr. pmid:6688256
Wilson L and Huang LS Effects of the fetal-placental unit on uterine prostaglandin levels at term in the pregnant rat. 1983 Prostaglandins pmid:6688474
Saldeen P and Saldeen T 6-keto-prostaglandin F1 alpha/thromboxane B2 ratio in vascular and lung tissue. 1983 Thromb. Res. pmid:6688484
Wilson TW Responses to furosemide in normotensive and hypertensive subjects. 1983 Clin. Pharmacol. Ther. pmid:6688772
Gurtner GH et al. Oxidant- and lipid-induced pulmonary vasoconstriction mediated by arachidonic acid metabolites. 1983 J Appl Physiol Respir Environ Exerc Physiol pmid:6688802
Hidaka T et al. Thromboxane formation from arachidonic acid and prostaglandin H2 in rabbit spleen. 1983 J. Biochem. pmid:6404897
Gerozissis K and Dray F In-vitro prostanoid production by the rat vas deferens. 1983 J. Reprod. Fertil. pmid:6572721
Okahara T et al. Zonal heterogeneity of prostaglandin and thromboxane release in the dog kidney. 1983 Prostaglandins pmid:6575405
Rojas J et al. Effects of cyclooxygenase inhibition on the response to group B streptococcal toxin in sheep. 1983 Pediatr. Res. pmid:6402752
Förster W and Pönicke K Influence of sympathomimetic drugs (1-phenyl-2-amino-ethan-1-ol derivatives) on the biosynthesis of prostaglandins and thromboxane B2. 1983 Br. J. Pharmacol. pmid:6403094
Nenci GG et al. Platelet malondialdehyde production kinetics after cyclooxygenase block. A study performed with a modified high sensitivity assay. 1983 Haemostasis pmid:6404715
Lewy RI Role of thromboxanes in vasotonic versus vaso-occlusive angina. 1983 Arch Mal Coeur Vaiss pmid:6407435
Hayashi Y et al. Enzyme immunoassay of thromboxane B2. 1983 Biochim. Biophys. Acta pmid:6407530
Poyser NL and Brydon LJ Prostaglandin release from the guinea-pig uterus superfused in vitro. Effect of stage of estrous cycle, progesterone, estradiol, oxytocin and A23187. 1983 Prostaglandins pmid:6408712
Butler RR et al. Gentamicin and indomethacin in the treatment of septic shock: effects on prostacyclin and thromboxane A2 production. 1983 J. Pharmacol. Exp. Ther. pmid:6339712
Laitinen O et al. Plasma levels and urinary excretion of prostaglandins in patients with rheumatoid arthritis. 1983 Clin. Rheumatol. pmid:6589104
Ouwendijk RJ et al. Raised plasma levels of thromboxane B2 in systemic mastocytosis. 1983 Eur. J. Clin. Invest. pmid:6409646
Asbóth G et al. Conversion of arachidonic acid to prostanoids in the avian uterus. 1983 Biochim. Biophys. Acta pmid:6402032