Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

Cross Reference

Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Periapical Periodontitis D010485 6 associated lipids
Placenta Diseases D010922 5 associated lipids
Platelet Storage Pool Deficiency D010981 3 associated lipids
Pleurisy D010998 20 associated lipids
Pneumonia D011014 10 associated lipids
Pneumonia, Aspiration D011015 3 associated lipids
Pneumonia, Viral D011024 3 associated lipids
Polycythemia Vera D011087 13 associated lipids
Adenomatous Polyposis Coli D011125 16 associated lipids
Pregnancy Complications D011248 19 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

Download all related citations
Per page 10 20 50 100 | Total 6367
Authors Title Published Journal PubMed Link
Nath KA et al. Regulatory role of prostanoids in glomerular microcirculation of remnant nephrons. 1987 Am. J. Physiol. pmid:3578532
Schuette AH et al. Effect of lung thromboxane generation on regional blood flow during sheep bypass. 1982 Am. J. Physiol. pmid:7065206
Yamamoto S et al. Endothelin causes portal and pulmonary hypertension in porcine endotoxemic shock. 1997 Am. J. Physiol. pmid:9087598
Düsing R et al. Dietary linoleic acid deprivation: effects on blood pressure and PGI2 synthesis. 1983 Am. J. Physiol. pmid:6337507
Wilkes BM and Mento PF Bradykinin-induced vasoconstriction and thromboxane release in perfused human placenta. 1988 Am. J. Physiol. pmid:3377072
Strand JC et al. Effect of imidazole on renal function in unilateral ureteral-obstructed rat kidneys. 1981 Am. J. Physiol. pmid:6787931
Katusić ZS et al. Endothelium-dependent contractions to oxygen-derived free radicals in the canine basilar artery. 1993 Am. J. Physiol. pmid:8456988
Simonson MS et al. Identification and transmembrane signaling of leukotriene D4 receptors in human mesangial cells. 1988 Am. J. Physiol. pmid:2849305
Olson NC et al. Pertussis toxin attenuates platelet-activating factor-induced pulmonary hemodynamic alterations in pigs. 1993 Am. J. Physiol. pmid:8460710
Chang SW and Ohara N Increased pulmonary vascular permeability in rats with biliary cirrhosis: role of thromboxane A2. 1993 Am. J. Physiol. pmid:8460713
Toyofuku T et al. Pulmonary vascular response to platelet-activating factor in conscious sheep. 1988 Am. J. Physiol. pmid:3414811
Zipser RD and Martin K Urinary excretion of arterial blood prostaglandins and thromboxanes in man. 1982 Am. J. Physiol. pmid:6950668
Amsterdam EA et al. Contractile actions of C5a on isolated porcine myocardium. 1992 Am. J. Physiol. pmid:1357981
Del Maschio A et al. Platelet activation by polymorphonuclear leukocytes exposed to chemotactic agents. 1990 Am. J. Physiol. pmid:2156456
Stephenson AH et al. 5,6-Epoxyeicosatrienoic acid reduces increases in pulmonary vascular resistance in the dog. 1998 Am. J. Physiol. pmid:9688901
Kruse-Elliott KT and Olson NC CGS 8515 and indomethacin attenuate cytokine-induced cardiopulmonary dysfunction in pigs. 1993 Am. J. Physiol. pmid:8386479
Schlondorff D and Satriano JA Interactions of vasopressin, cAMP, and prostaglandins in toad urinary bladder. 1985 Am. J. Physiol. pmid:2579584
Stenmark KR et al. Alveolar inflammation and arachidonate metabolism in monocrotaline-induced pulmonary hypertension. 1985 Am. J. Physiol. pmid:3923843
Scharschmidt LA et al. Angiotensin II and eicosanoids in the control of glomerular size in the rat and human. 1986 Am. J. Physiol. pmid:2936254
Cudd TA and Wood CE Thromboxane A2 receptor antagonism prevents hormonal and cardiovascular responses to mineral acid infusion. 1994 Am. J. Physiol. pmid:7977850
Wagerle LC et al. Effect of dexamethasone on cerebral prostanoid formation and pial arteriolar reactivity to CO2 in newborn pigs. 1991 Am. J. Physiol. pmid:1901460
Del Balzo U et al. Complement C5a-mediated myocardial ischemia and neutrophil sequestration: two independent phenomena. 1993 Am. J. Physiol. pmid:8447449
Titos E et al. Hepatocytes are a rich source of novel aspirin-triggered 15-epi-lipoxin A(4). 1999 Am. J. Physiol. pmid:10564079
Takashio T et al. Inhibitory effect of pindolol on hypoxic pulmonary vasoconstriction. 1992 Am. J. Physiol. pmid:1310232
Schrör K et al. Preservation of ischemic myocardium by pinane thromboxane A2. 1980 Am. J. Physiol. pmid:7356037
Sata T et al. Paraquat-induced lung injury: prevention by N-tert-butyl-alpha-phenylnitrone, a free-radical spin-trapping agent. 1992 Am. J. Physiol. pmid:1311515
Garfield RE et al. Gap junction formation in myometrium: control by estrogens, progesterone, and prostaglandins. 1980 Am. J. Physiol. pmid:7369350
Lampugnani MG and de Gaetano G Effects of metabolized and unmetabolized arachidonate on rat platelet shape change. 1984 Am. J. Physiol. pmid:6433724
Ahlquist DA et al. Factors influencing metabolism of arachidonic acid in guinea pig gastric mucosa. 1983 Am. J. Physiol. pmid:6401937
Murray MJ et al. Select dietary fatty acids attenuate cardiopulmonary dysfunction during acute lung injury in pigs. 1995 Am. J. Physiol. pmid:8594921
Wilkes BM et al. Characterization of glomerular thromboxane receptor sites in the rat. 1989 Am. J. Physiol. pmid:2525345
Kalichman MW et al. Effects of cocaine on blood flow and prostaglandin metabolites in rat sciatic nerve. 1994 Am. J. Physiol. pmid:8024013
Reyes AA and Klahr S Bladder contributes to eicosanoids excreted in urine. 1990 Am. J. Physiol. pmid:2240235
Klotman PE et al. Thromboxane synthetase inhibition improves function of hydronephrotic rat kidneys. 1986 Am. J. Physiol. pmid:3456211
Chen L et al. Cyclooxygenase inhibition decreases nitric oxide synthase activity in human platelets. 1997 Am. J. Physiol. pmid:9362253
Wilkes BM et al. Endothelin receptors in human placenta: relationship to vascular resistance and thromboxane release. 1990 Am. J. Physiol. pmid:2159236
Beck N and Shaw JO Thromboxane B2 and prostaglandin E2 in the K+-depleted rat kidney. 1981 Am. J. Physiol. pmid:7468800
Reinke M Monitoring thromboxane in body fluids: a specific ELISA for 11-dehydrothromboxane B2 using a monoclonal antibody. 1992 Am. J. Physiol. pmid:1590375
Addonizio VP et al. Effects of verapamil and diltiazem on human platelet function. 1986 Am. J. Physiol. pmid:3006516
Gyenes M and De Groot H Prostanoid release by Kupffer cells upon hypoxia-reoxygenation: role of pHi and Cai2+. 1993 Am. J. Physiol. pmid:8384798
Brown GP and Venuto RC In vitro renal eicosanoid production during pregnancy in rabbits. 1988 Am. J. Physiol. pmid:3287949
Burch RM and Halushka PV Vasopressin stimulates prostaglandin and thromboxane synthesis in toad bladder epithelial cells. 1982 Am. J. Physiol. pmid:6816073
Bradley LM et al. Circulatory effects of PAF-acether in newborn piglets. 1989 Am. J. Physiol. pmid:2912183
Zipser RD Effects of selective inhibition of thromboxane synthesis on renal function in humans. 1985 Am. J. Physiol. pmid:3839111
Fletcher MP et al. C5a-induced myocardial ischemia: role for CD18-dependent PMN localization and PMN-platelet interactions. 1993 Am. J. Physiol. pmid:7902015
Kauser K and Rubanyi GM Gender difference in bioassayable endothelium-derived nitric oxide from isolated rat aortae. 1994 Am. J. Physiol. pmid:7810731
Stahl RA et al. High protein intake stimulates glomerular prostaglandin formation in remnant kidneys. 1987 Am. J. Physiol. pmid:3473940
Sirko S et al. Prostaglandin formation in the hypothalamus in vivo: effect of pyrogens. 1989 Am. J. Physiol. pmid:2784289
Farman N et al. PGE2, PGF2 alpha, 6-keto-PGF1 alpha, and TxB2 synthesis along the rabbit nephron. 1987 Am. J. Physiol. pmid:3101513
Miyazaki Y et al. Selective turnover of sarcolemmal phospholipids with lethal cardiac myocyte injury. 1990 Am. J. Physiol. pmid:2382705