Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Edema, Cardiac D004489 1 associated lipids
Osteoblastoma D018215 1 associated lipids
Radiculopathy D011843 1 associated lipids
Oligomenorrhea D009839 1 associated lipids
Erythromelalgia D004916 1 associated lipids
Intracranial Hemorrhage, Hypertensive D020299 1 associated lipids
Heart Septal Defects D006343 2 associated lipids
Retinal Vein Occlusion D012170 2 associated lipids
Weil Disease D014895 2 associated lipids
Drowning D004332 2 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

Download all related citations
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Authors Title Published Journal PubMed Link
Foegh ML et al. Eicosanoids, gamma-interferon and inflammatory cells in kidney transplant patients. 1986 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:2949550
Pedrinelli R et al. The influence of selective and nonselective prostaglandin inhibition on renin. 1985 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:3159197
Ezra D et al. Effects of platelet-activating factor on coronary hemodynamics and coronary venous plasma levels of TXB2, 6-keto-PGF1 alpha, and leukotriene C4 immunoreactivity in the intact domestic pig heart. 1985 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:3159202
Gensini GF et al. Effects of dipyridamole infusion on local platelet aggregation and local formation of thromboxane A2 in patients with pulmonary hypertension. 1985 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:3159209
De Caterina R et al. Aspirin after acute myocardial infarction: a systematic approach to compare the hemostatic effects of three different doses. 1985 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:3159210
Trimarco B et al. Indomethacin blunts the late phase of nitroglycerin-induced coronary vasodilatation in dogs. 1985 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:3159220
Yamamoto S et al. Enzyme immunoassay of thromboxane B2 and 6-keto-prostaglandin F1 alpha as a substitute for radioimmunoassay. 1983 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:6221523
Weerasekera DA et al. Chemiluminescence immunoassay of thromboxane B2. 1983 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:6221524
Ito T et al. Effects of a selective inhibitor of thromboxane synthetase (OKY-1581) in humans. 1983 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:6221531
FitzGerald GA et al. Aspirin inhibits endogenous prostacyclin and thromboxane biosynthesis in man. 1983 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:6221534
van der Giessen WJ et al. Acute effect of cigarette smoking on cardiac prostaglandin synthesis and platelet behavior in patients with coronary heart disease. 1983 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:6221546
Bach MK et al. In vivo and in vitro actions of a new selective inhibitor of leukotriene C and D synthesis. 1983 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:6221551
Grose JH et al. Imbalanced prostacyclin and thromboxane A2 production in essential hypertension. 1983 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:6221555
Hornych A et al. Thromboxane B2 in borderline and essential hypertension. 1983 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:6221556
MacIntyre DE et al. Role of endogenous arachidonate metabolites in phospholipid-induced human platelet activation. 1983 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:6221557
Krishnamurthi S et al. Paradoxical effects of indomethacin and trifluoperazine on Ca2+ ionophore A23187-induced human platelet aggregation, thromboxane B2 production, and dense granule release. 1983 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:6221559
Lecompte T et al. Interference of transmethylation inhibitors with thromboxane synthesis in rat platelets: evidence for the requirement of a methyl transfer reaction in platelet activation. 1983 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:6221560
Patrono C et al. Evidence for a renal origin of urinary thromboxane B2 in health and disease. 1983 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:6221569
Patrignani P et al. Characterization of the cyclooxygenase activity of human blood prostaglandin endoperoxide synthases. 1995 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:7732817
Foegh ML et al. Urinary thromboxane has diagnostic value in myocardial infarction. 1995 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:7732879