Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Bluetongue D001819 1 associated lipids
Atrial Premature Complexes D018880 1 associated lipids
Gastric Dilatation D013271 1 associated lipids
Latex Hypersensitivity D020315 1 associated lipids
Stomach Volvulus D013277 1 associated lipids
Foot Rot D005535 1 associated lipids
Aortic Arch Syndromes D001015 2 associated lipids
Mixed Connective Tissue Disease D008947 2 associated lipids
Tachycardia, Paroxysmal D013614 2 associated lipids
Fibromuscular Dysplasia D005352 2 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

Download all related citations
Per page 10 20 50 100 | Total 6367
Authors Title Published Journal PubMed Link
Chignard M et al. Arachidonate-mediated bronchoconstriction and platelet activation are inhibited by microgram doses of compound L8027 which are not selective for thromboxane synthetase. 1979 Agents Actions Suppl. pmid:291306
Peskar BA and Holland A Plasma levels of immunoreactive 15-keto-13,14-dihydro-thromboxane B2 in guinea pigs during anaphylaxis and after histamine injection. 1979 Agents Actions Suppl. pmid:294148
Cerletti C et al. Comparison of the effects of oral and intravenous aspirin administration on platelet and peripheral vascular cyclo-oxygenase activity: studies in rats and in man. 1986 Agents Actions Suppl. pmid:3101444
Mihai K et al. Association between total cholesterol and thromboxane B2 levels in offspring of parents suffering from premature coronary artery disease. 1992 Agents Actions Suppl. pmid:1632293
Petö J et al. Association between total cholesterol and plasma thromboxane B2 in human adults. 1992 Agents Actions Suppl. pmid:1632296
Mentz P and Giessler C Biosynthesis of TXB2 and 6-oxo-PGF1 alpha in the heart and other tissues under pathophysiological conditions. 1992 Agents Actions Suppl. pmid:1632315
Fernández-Cruz E et al. Increased synthesis and production of prostaglandin E2 by monocytes from drug addicts with AIDS. 1989 AIDS pmid:2496725
Shalina RI et al. [Synthesis of prostaglandins and lipid peroxidation in pregnant women with gestosis]. 1988 Akush Ginekol (Mosk) pmid:3213902
Bashakin NF et al. [The functional characteristics of the prostacyclin-thromboxane system in newborn infants with a history of acute and chronic intrauterine hypoxia]. 1993 Akush Ginekol (Mosk) pmid:8311150
Siler-Khodr TM et al. Effect of ethanol on thromboxane and prostacyclin production in the human placenta. 2000 Alcohol pmid:10963940
Hillbom M et al. Effects of ethanol on platelet function. 1985 May-Jun Alcohol pmid:4026960
Signore C et al. Markers of oxidative stress and systemic vasoconstriction in pregnant women drinking > or =48 g of alcohol per day. 2008 Alcohol. Clin. Exp. Res. pmid:18715278
Collins CE et al. Picotamide inhibition of excess in vitro thromboxane B2 release by colorectal mucosa in inflammatory bowel disease. 1996 Aliment. Pharmacol. Ther. pmid:8791957
Treiber G et al. The effect of single-dose naproxen on eicosanoid formation in human gastroduodenal mucosa. 2006 Aliment. Pharmacol. Ther. pmid:16393293
Van Hecken A et al. Effects of enteric-coated, low-dose aspirin on parameters of platelet function. 2002 Aliment. Pharmacol. Ther. pmid:12197849
Cole AT et al. Low dose aspirin: selective inhibition of rectal dialysis thromboxane B2 in healthy volunteers. 1994 Aliment. Pharmacol. Ther. pmid:7865644
Carty E et al. Ridogrel, a dual thromboxane synthase inhibitor and receptor antagonist: anti-inflammatory profile in inflammatory bowel disease. 2000 Aliment. Pharmacol. Ther. pmid:10848666
Wannhoff A et al. Cardiac volume overload and pulmonary hypertension in long-term follow-up of patients with a transjugular intrahepatic portosystemic shunt. 2016 Aliment. Pharmacol. Ther. pmid:26919285
Tanaka H et al. Leukotriene (LT)-receptor antagonist is more effective in asthmatic patients with a low baseline ratio of urinary LTE4 to 2,3-dinor-6-keto-prostaglandin (PG)F1alpha. 1999 Allergy pmid:10380781
Mita H et al. Possible involvement of mast-cell activation in aspirin provocation of aspirin-induced asthma. 2001 Allergy pmid:11703219