Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Basal Ganglia Hemorrhage D020145 1 associated lipids
Osteoblastoma D018215 1 associated lipids
Edema, Cardiac D004489 1 associated lipids
Radiculopathy D011843 1 associated lipids
Erythromelalgia D004916 1 associated lipids
Oligomenorrhea D009839 1 associated lipids
Fibromuscular Dysplasia D005352 2 associated lipids
Heart Septal Defects D006343 2 associated lipids
Retinal Vein Occlusion D012170 2 associated lipids
Weil Disease D014895 2 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

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Authors Title Published Journal PubMed Link
González-Correa JA et al. Gender differences in the effect of aspirin on retinal ischemia, prostanoid synthesis and nitric oxide production in experimental type 1-like diabetes. 2007 Aug-Sep Vascul. Pharmacol. pmid:17581795
Sinzinger H et al. 20 mg aspirin daily--evidence for a clinical future of this extremely low-dose in arterial disease? 1988 VASA pmid:3369232
Strobl-Jäger E et al. Platelet half-life in comparison to other in-vivo platelet function parameters such as thromboxane B2, beta-thromboglobulin and platelet factor 4 in patients with atherosclerotic lesions with and without hyperlipoproteinemia. 1986 VASA pmid:2948337
Ditter H and Matthias FR Changes in thromboxane formation by platelets during and after a continuous endotoxin infusion into rabbits. 1984 VASA pmid:6516562
Fitscha P et al. Follow-up of in-vivo platelet function (platelet half-life, thromboxane B2) in patients with coronary heart disease. 1984 VASA pmid:6516563
Rebrov BA [Role of thromboxane A2 (B2) in the pathogenesis of stress proteinuria in healthy persons]. 2001 Mar-Apr Urologiia pmid:11490711
Frøkiaer J et al. Renal blood flow and pelvic pressure after 4 weeks of total upper urinary tract obstruction in the pig. The effect of a TxA2 synthetase inhibitor on active preglomerular vasoconstriction. 1988 Urol. Res. pmid:3413908
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Greenstein A et al. The role of oxygen free radicals and prostaglandins in reperfusion injury to warm ischemic kidneys. 1991 Urol. Res. pmid:1759334
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Jokela R et al. Effect of in vitro stability of dietary fish oil on lipid peroxidation and prostanoids in vivo. 1998 Ups. J. Med. Sci. pmid:10052110
Persico N et al. Transdermal HRT and Doppler findings in normotensive and hypertensive postmenopausal patients. 2005 Ultrasound Obstet Gynecol pmid:16184506
Komarevtseva IA et al. [Change in prostanoid metabolism in cystic kidney lesion]. 1997 Sep-Dec Ukr. Biokhim. Zh. pmid:9606841
Midttun M et al. [Thrombocyte aggregation and serum thromboxane in patients with acute myocardial infarction]. 1990 Ugeskr. Laeg. pmid:2275044
Lyck F et al. [Thrombocyte aggregation and serum thromboxane B2 in patients with unstable angina pectoris treated with diltiazem or verapamil]. 1992 Ugeskr. Laeg. pmid:1462402
Balkhy HH et al. Comparison of Eurocollins and University of Wisconsin solution in single flush preservation of the ischemic reperfused lung: an in vivo rabbit model. 1995 Transplantation pmid:7732552
Khirabadi BS et al. Urine immunoreactive thromboxane B2 in rat cardiac allograft rejection. 1985 Transplantation pmid:3880966
Smith SR et al. Chronic thromboxane synthase inhibition with CGS 12970 in human cyclosporine nephrotoxicity. 1993 Transplantation pmid:8279014
Proppe DG et al. Diagnostic value of urinary thromboxane B2 concentration in detection of initial acute rejection reactions in human renal allografts. 1995 Transplantation pmid:7709445
Santillan-Doherty P et al. Urinary thromboxane B2 as an indicator of acute rejection in lung allotransplantation. 1988 Transplantation pmid:3285529