Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Angina Pectoris D000787 27 associated lipids
Angina Pectoris, Variant D000788 3 associated lipids
Angina, Unstable D000789 14 associated lipids
Hypoxia D000860 23 associated lipids
Aortic Aneurysm D001014 8 associated lipids
Aortic Arch Syndromes D001015 2 associated lipids
Aortic Rupture D001019 3 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Arterial Occlusive Diseases D001157 12 associated lipids
Arteriosclerosis D001161 86 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

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Per page 10 20 50 100 | Total 6367
Authors Title Published Journal PubMed Link
Goldberg RN et al. Effects of a leukotriene antagonist on the early hemodynamic manifestations of group B streptococcal sepsis in piglets. 1986 Pediatr. Res. pmid:3534778
Kirschenbaum MA Prostanoids and renal failure. A hypothetical role for prostanoids in progressive renal disease. 1986 Contrib Nephrol pmid:3802815
Westlund P et al. Identification of 11-dehydro-TXB2 as a suitable parameter for monitoring thromboxane production in the human. 1986 Prostaglandins pmid:3755250
Granström E Methodology in prostaglandin and thromboxane assay. 1986 Prog. Lipid Res. pmid:3321087
Shohami E and Feuerstein G T-2 toxemia and brain prostaglandins. 1986 Prostaglandins pmid:3457405
Noonan TC and Malik AB Pulmonary vascular response to leukotriene D4 in unanesthetized sheep: role of thromboxane. 1986 J. Appl. Physiol. pmid:3957828
Kiviniemi H and Rämo OJ The behaviour of prostanoids during the course of acute experimental pancreatitis in rats. 1986 Res Exp Med (Berl) pmid:3823620
Altman R et al. Synergistic actions of PAF-acether and sodium arachidonate in human platelet aggregation. 1. Studies in normal human platelet rich plasma. 1986 Thromb. Res. pmid:3014677
Friesinger GC and Robertson RM Vasospastic angina: a continuing search for mechanism(s). 1986 J. Am. Coll. Cardiol. pmid:3510238
Emms H and Lewis GP The roles of prostaglandin endoperoxides, thromboxane A2 and adenosine diphosphate in collagen-induced aggregation in man and the rat. 1986 Br. J. Pharmacol. pmid:3082399
Nagatsuka K et al. A new approach to antithrombotic therapy--evaluation of combined therapy of thromboxane synthetase inhibitor and very low dose of aspirin. 1985 Sep-Oct Stroke pmid:3931302
Codde JP et al. Changes in prostanoid synthesis in response to diet and hypertension in one-kidney, one clip rats. 1985 Nov-Dec Hypertension pmid:3908314
Lamy M et al. Biochemical pathways of acute lung injury. 1985 May-Jun Bull Eur Physiopathol Respir pmid:3873973
Jolly SR et al. Platelet depletion in experimental myocardial infarction. 1985 May-Jun Basic Res. Cardiol. pmid:4026785
Hillbom M et al. Effects of ethanol on platelet function. 1985 May-Jun Alcohol pmid:4026960
Uyama O et al. The effect of a thromboxane synthetase inhibitor, OKY-046, on urinary excretion of immunoreactive thromboxane B2 and 6-keto-prostaglandin F1 alpha in patients with ischemic cerebrovascular disease. 1985 Mar-Apr Stroke pmid:3883580
Fujimoto T et al. Cerebrovascular injuries induced by activation of platelets in vivo. 1985 Mar-Apr Stroke pmid:3975962
Mullane KM and McGiff JC Platelet depletion and infarct size in an occlusion-reperfusion model of myocardial ischemia in anesthetized dogs. 1985 Jul-Aug J. Cardiovasc. Pharmacol. pmid:2410715
Miura K et al. Effect of SA-446, an angiotensin-converting enzyme inhibitor, on renal function in anesthetized dogs: special reference to arachidonic acid metabolites. 1985 Jan-Feb J. Cardiovasc. Pharmacol. pmid:2580127
Olanoff LS et al. Protective effects of trans-13-APT, a thromboxane receptor antagonist, in endotoxemia. 1985 Jan-Feb J. Cardiovasc. Pharmacol. pmid:2580129
Hook BG et al. Experimental coronary artery thrombosis in the absence of thromboxane A2 synthesis: evidence for alternate pathways for coronary thrombosis. 1985 Jan-Feb J. Cardiovasc. Pharmacol. pmid:2580139
Fisher M and Zipser R Increased excretion of immunoreactive thromboxane B2 in cerebral ischemia. 1985 Jan-Feb Stroke pmid:3966251
Papanicolaou N et al. Selective inhibition of renal thromboxane biosynthesis increased sodium excretion rate in normal and saline-loaded rats. 1985 Clin. Sci. pmid:3880524
Brown EM and Swartz SL Production of prostaglandins by dispersed cells and fragments from bovine parathyroid glands. 1985 Prostaglandins pmid:3883430
Ding YA et al. Angiotensin II effects on platelet function. 1985 J Hypertens Suppl pmid:2856711
Boraschi D et al. Regulation of arachidonic acid metabolism in macrophages by immune and nonimmune interferons. 1985 J. Immunol. pmid:3923110
Ment LR et al. Randomized indomethacin trial for prevention of intraventricular hemorrhage in very low birth weight infants. 1985 J. Pediatr. pmid:3906073
Slotman GJ et al. Thromboxane, prostacyclin, and the hemodynamic effects of graded bacteremic shock. 1985 Circ. Shock pmid:3915237
De Caterina R et al. Nitrates and endothelial prostacyclin production: studies in vitro. 1985 Circulation pmid:3917245
Walenga RW et al. Megakaryocyte thromboxane production induced by platelet stimuli during in vitro culture. 1985 Exp. Hematol. pmid:3918879
Walsh SW Preeclampsia: an imbalance in placental prostacyclin and thromboxane production. 1985 Am. J. Obstet. Gynecol. pmid:3923838
Nitz RE and Martorana PA The activity of molsidomine in experimental models of ischemic cardiac disease. 1985 Am. Heart J. pmid:3919549
Bowers GJ et al. Prostanoid production by lipopolysaccharide-stimulated Kupffer cells. 1985 J. Surg. Res. pmid:3887037
Kiyomiya K and Oh-ishi S Involvement of arachidonic acid metabolites in acute inflammation: detection of 6-keto-PGF1 alpha, thromboxane B2 and PGD2 in rat pleurisy induced by phorbol myristate acetate. 1985 Jpn. J. Pharmacol. pmid:3936958
Bottoms GD et al. Endotoxin-induced eicosanoid production by equine vascular endothelial cells and neutrophils. 1985 Circ. Shock pmid:3919961
Stenmark KR et al. Alveolar inflammation and arachidonate metabolism in monocrotaline-induced pulmonary hypertension. 1985 Am. J. Physiol. pmid:3923843
McKechnie K et al. Metabolic and cardiovascular effects of endotoxin infusion in conscious unrestrained rats: effects of methylprednisolone and BW755C. 1985 Circ. Shock pmid:3919962
Toivanen J et al. Differential inhibition of platelet thromboxane and lung prostacyclin production by sulphinpyrazone, acetylsalicylic acid and indomethacin by human tissues in vitro. 1985 Thromb. Res. pmid:3920778
Quilley J and McGiff JC Arachidonic acid metabolism and urinary excretion of prostaglandins and thromboxane in rats with experimental diabetes mellitus. 1985 J. Pharmacol. Exp. Ther. pmid:3925127
Yamaguchi M and Mori N 6-Keto prostaglandin F1 alpha, thromboxane B2, and 13,14-dihydro-15-keto prostaglandin F concentrations of normotensive and preeclamptic patients during pregnancy, delivery, and the postpartum period. 1985 Am. J. Obstet. Gynecol. pmid:3838119
O'Keefe EH et al. Effects of a thromboxane synthetase inhibitor and a thromboxane antagonist on release and activity of thromboxane A2 and prostacyclin in vitro. 1985 Prostaglandins pmid:3925501
Numano F et al. Prostacyclin and variant angina. 1985 Ann. N. Y. Acad. Sci. pmid:3865605
Strano A et al. [Formation of platelet thromboxane in a patient with type I glycogenosis]. 1985 Recenti Prog Med pmid:3868788
Jensen W et al. Hemodynamic measurements in a sheep model with a hollow fiber artificial kidney containing modified cellulose. 1985 Life Support Syst pmid:3870598
Kopp KJ et al. Template bleeding time and thromboxane generation in the horse: effects of three non-steroidal anti-inflammatory drugs. 1985 Equine Vet. J. pmid:3878280
Conti P et al. Enhanced thromboxane synthesis and vacuolization in human polymorphonuclear leucocytes induced by human lymphokine containing supernatants. 1985 Clin. Rheumatol. pmid:3879473
Mahiout A et al. Ex vivo model for pre-clinical evaluation of dialyzers containing new membranes. 1985 Life Support Syst pmid:3879954
Wang JP et al. Antiplatelet effect of hsien-ho-t'sao (Agrimonia pilosa). 1985 Am. J. Chin. Med. pmid:3927704
Hashimoto Y et al. Time-dependent inhibition of the cyclooxygenase pathway by 12-hydroperoxy-5,8,10,14-eicosatetraenoic acid. 1985 Biochem. Biophys. Res. Commun. pmid:3927909
Shephard EG et al. Lung function and plasma levels of thromboxane B2, 6-ketoprostaglandin F1 alpha and beta-thromboglobulin in antigen-induced asthma before and after indomethacin pretreatment. 1985 Br J Clin Pharmacol pmid:2581599
Meyrick B et al. Endothelial prostacyclin production is a late event in granulocyte migration into bovine pulmonary artery intimal explants. 1985 Blood pmid:3904871
Janka HU Platelet and endothelial function tests during metformin treatment in diabetes mellitus (short communication). 1985 Horm. Metab. Res. Suppl. pmid:2934311
Hayashi C [Thromboxane B2 in surgery]. 1985 Nihon Geka Gakkai Zasshi pmid:2935731
Steinhauer HB et al. Thromboxane B2 and beta 2-microglobulin as early indicators of renal allograft rejection. 1985 Proc Eur Dial Transplant Assoc Eur Ren Assoc pmid:3887370
Lenhard V et al. Transfusion-induced enhancement of prostaglandin and thromboxane release in prospective kidney graft recipients. 1985 Proc Eur Dial Transplant Assoc Eur Ren Assoc pmid:3887386
Naesh O et al. Platelet function in surgical stress. 1985 Thromb. Haemost. pmid:2935969
Takahata K et al. [Effect of PSK on prostaglandin metabolism (I)]. 1985 Gan To Kagaku Ryoho pmid:3888117
Miyazaki H et al. Microdetermination of prostaglandins and thromboxane B2 by gas chromatography/high-resolution selected-ion monitoring. 1985 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:2936139
Hutchison AA et al. Effect of endotoxemia on hypoxic pulmonary vasoconstriction in unanesthetized sheep. 1985 J. Appl. Physiol. pmid:3888946
Kobayashi N et al. Effect of changes in prostaglandin synthesis by platelets and vessel wall on the formation of arterial thrombosis in rabbits. 1985 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:2936159
Ogawa K et al. Effects of orally administered glandular kallikrein on urinary kallikrein and prostaglandin excretion, plasma immunoreactive prostanoids and platelet aggregation in essential hypertension. 1985 Klin. Wochenschr. pmid:3889484
Nishikawa K et al. (E)-7-Phenyl-7-(3-pyridyl)-6-heptenoic acid (CV-4151): a potent, specific thromboxane A2 synthetase inhibitor. 1985 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:2936160
Vapaatalo H Prostaglandins and coronary circulation. 1985 Acta Med. Scand. Suppl. pmid:3890471
Takagi S and Den K Prostacyclin and thromboxane A2 in preeclamptic umbilical circulation. 1985 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:2936183
Ylikorkala O and Mäkilä UM Prostacyclin and thromboxane in gynecology and obstetrics. 1985 Am. J. Obstet. Gynecol. pmid:3890549
Greer IA et al. Immunoreactive prostacyclin and thromboxane metabolites in normal pregnancy and the puerperium. 1985 Br J Obstet Gynaecol pmid:3890936
Pedersen AK and FitzGerald GA Cyclooxygenase inhibition, platelet function, and metabolite formation during chronic sulfinpyrazone dosing. 1985 Clin. Pharmacol. Ther. pmid:3917387
Barst RJ et al. Relation of arachidonate metabolites to abnormal control of the pulmonary circulation in a child. 1985 Am. Rev. Respir. Dis. pmid:3917630
Stuart MJ and Dusse J In vitro comparison of the efficacy of cyclooxygenase inhibitors on the adult versus neonatal platelet. 1985 Biol. Neonate pmid:4005330
Amado JA et al. Influence of acetylsalicylic acid on bleeding time and serum thromboxane B2 in diabetes mellitus type I. 1985 Diabete Metab pmid:4007228
De Servi S et al. [Myocardial ischemia during exertion. Correlations between blood levels of thromboxane B2 and changes in coronary flow and resistance]. 1985 G Ital Cardiol pmid:4007353
McGinley S et al. The effect of inhibiting brain thromboxane biosynthesis on pentylenetetrazole-induced seizure threshold. 1985 J. Neurosci. Res. pmid:4009745
Mehta P et al. Decreased platelet aggregation but increased thromboxane A2 generation in polycythemia vera. 1985 Arch. Intern. Med. pmid:4015270
Kelton JG et al. A platelet function defect in preeclampsia. 1985 Obstet Gynecol pmid:3966011
Halenda SP et al. Phorbol esters and oleoyl acetoyl glycerol enhance release of arachidonic acid in platelets stimulated by Ca2+ ionophore A23187. 1985 J. Biol. Chem. pmid:3930496
Mundie TG et al. Byssinosis: Release of prostaglandins, thromboxane, and 5-hydroxytryptamine in bronchopulmonary lavage fluid after inhalation of cotton dust extracts. 1985 Am. J. Pathol. pmid:3966532
Mendieta CF et al. Biosynthesis of prostaglandins in gingiva of patients with chronic periodontitis. 1985 J. Periodontol. pmid:3919173
Seitz M and Hunstein W Enhanced prostanoid release from monocytes of patients with rheumatoid arthritis and active systemic lupus erythematosus. 1985 Ann. Rheum. Dis. pmid:4026405
Freund HR et al. Muscle prostaglandin production in the rat. Effect of abdominal sepsis and different amino acid formulations. 1985 Arch Surg pmid:4026556
Haurand M and Ullrich V Isolation and characterization of thromboxane synthase from human platelets as a cytochrome P-450 enzyme. 1985 J. Biol. Chem. pmid:2999104
Prosdocimi M et al. Inhibition by AD6 (8-monochloro-3-beta-diethylaminoethyl-4-methyl-7-ethoxycarbonyl methoxy coumarin) of platelet aggregation in dog stenosed coronary artery. 1985 Thromb. Res. pmid:3840290
Lelcuk S et al. Thromboxane A2 moderates permeability after limb ischemia. 1985 Ann. Surg. pmid:3840349
Morris HG et al. Effects of salsalate (nonacetylated salicylate) and aspirin on serum prostaglandins in humans. 1985 Ther Drug Monit pmid:3866409
Wilson L and Huang LS Contributions of the fetoplacental unit to augmented uterine prostaglandin levels periparturition in the rat. 1985 Biol. Reprod. pmid:3840391
Levine RF et al. Megakaryocyte interaction with subendothelial extracellular matrix is associated with adhesion, platelet-like shape change, and thromboxane A2 production. 1985 Blood pmid:4027379
Templeton CB et al. Effects of repeated endotoxin injections on prostanoids, hemodynamics, endothelial cells, and survival in ponies. 1985 Circ. Shock pmid:3840414
Roberts DG et al. Sulindac is not renal sparing in man. 1985 Clin. Pharmacol. Ther. pmid:4028619
Fink MP et al. Plasma levels of 6-keto PGF1 alpha but not TxB2 increase in rats with peritonitis due to cecal ligation. 1985 Circ. Shock pmid:3840415
Codde JP et al. Study of diet and drug interactions on prostanoid metabolism. 1985 Prostaglandins pmid:4034991
Wise WC et al. Ibuprofen, methylprednisolone, and gentamicin as conjoint therapy in septic shock. 1985 Circ. Shock pmid:3840416
Brace LD and Fareed J An objective assessment of the interaction of heparin and its fractions with human platelets. 1985 Semin. Thromb. Hemost. pmid:4035366
Demling RH et al. Role of subcutaneous tissue endotoxin in the production of prostanoid-induced lung injury: comparison with intravenous endotoxin response. 1985 Circ. Shock pmid:3840417
Takeda H et al. [Early changes of vasoactive prostanoids in patients with mitral valve replacement]. 1985 Nihon Kyobu Geka Gakkai Zasshi pmid:3840511
Chang J et al. Modulation by hydroxyeicosatetraenoic acids (HETEs) of arachidonic acid metabolism in mouse resident peritoneal macrophages. 1985 Eur. J. Pharmacol. pmid:3920057
Shohami E and Gross J An ex vivo method for evaluating prostaglandin synthetase activity in cortical slices of mouse brain. 1985 J. Neurochem. pmid:3923156
Gay SW and Kosher RA Prostaglandin synthesis during the course of limb cartilage differentiation in vitro. 1985 J Embryol Exp Morphol pmid:3867724
Fukushima M et al. [Role of thromboxane A2 in pulmonary air embolism in conscious sheep]. 1985 Kokyu To Junkan pmid:4023449
Conti P et al. Effect of supernatants from PHA-stimulated and non-stimulated lymphocyte cultures on thromboxane B2 release by polymorphonuclear leukocytes in vitro. 1985 Agents Actions pmid:4003201
Carter AJ and Hanley SP The effect of platelet number and haematocrit on whole blood thromboxane synthesis. 1985 Thromb. Haemost. pmid:4024033
Kawaguchi A et al. Increase in urinary thromboxane B2 in rats caused by cyclosporine. 1985 Transplantation pmid:4024243