Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

Cross Reference

Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Angina Pectoris D000787 27 associated lipids
Angina Pectoris, Variant D000788 3 associated lipids
Angina, Unstable D000789 14 associated lipids
Hypoxia D000860 23 associated lipids
Aortic Aneurysm D001014 8 associated lipids
Aortic Arch Syndromes D001015 2 associated lipids
Aortic Rupture D001019 3 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Arterial Occlusive Diseases D001157 12 associated lipids
Arteriosclerosis D001161 86 associated lipids
Per page 10 20 50 100 | Total 293

PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

Download all related citations
Per page 10 20 50 100 | Total 6367
Authors Title Published Journal PubMed Link
Svensson J and Samuelsson K Inhibition of platelet function by low dose acetylsalicylic acid in patients with cerebrovascular disease. 1983 Thromb. Res. pmid:20218005
Drake TS et al. Peritoneal fluid prostanoids in unexplained infertility. 1983 Am. J. Obstet. Gynecol. pmid:6614085
Deckmyn H et al. Manipulation of the local thromboxane and prostacyclin balance in vivo by the antithrombotic compounds dazoxiben, acetylsalicylic acid and nafazatrom. 1983 Biochem. Pharmacol. pmid:6578796
Goetzl EJ et al. Enhancement of human neutrophil adherence by synthetic leukotriene constituents of the slow-reacting substance of anaphylaxis. 1983 Immunology pmid:6193056
McManus LM et al. Thromboxane B2 (TxB2) release following acetyl glyceryl ether phosphorylcholine (AGEPC) infusion in the rabbit. 1983 Immunopharmacology pmid:6832960
Martin JL et al. Effect of atrial pacing on intracoronary thromboxane production in coronary artery disease. 1983 J. Am. Coll. Cardiol. pmid:6833660
Ferraris VA and Swanson E Aspirin usage and perioperative blood loss in patients undergoing unexpected operations. 1983 Surg Gynecol Obstet pmid:6836459
Margotat A et al. A rapid and simple assay for the study of thromboxane B2 synthesis by intact human platelets. 1983 J Pharmacol Methods pmid:6843139
Palmer RM and Salmon JA Release of leukotriene B4 from human neutrophils and its relationship to degranulation induced by N-formyl-methionyl-leucyl-phenylalanine, serum-treated zymosan and the ionophore A23187. 1983 Immunology pmid:6309653
Nordøy A et al. Platelets and coagulation in patients with familial hypercholesterolemia (type IIa). 1983 Acta Med Scand pmid:6188328
Menys VC and Davies JA Inhibitory effects of ZK 36374, a stable prostacyclin analogue, on adhesion of rabbit platelets to damaged aorta and serotonin release by adherent platelets. 1983 Clin. Sci. pmid:6190604
Hartung HP and Toyka KV Activation of macrophages by substance P: induction of oxidative burst and thromboxane release. 1983 Eur. J. Pharmacol. pmid:6191998
Kangasaho M et al. Formation of thromboxane B2 by platelets and concentrations of thromboxane B2 and 6-keto-prostaglandin F1 alpha in plasma after acute ethanol ingestion. 1983 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:6303086
Samuelsson B From studies of biochemical mechanism to novel biological mediators: prostaglandin endoperoxides, thromboxanes, and leukotrienes. Nobel Lecture, 8 December 1982. 1983 Biosci. Rep. pmid:6315101
Gorman RR et al. Inhibition of platelet thromboxane A2 synthase activity by sodium 5-(3'-pyridinylmethyl)benzofuran-2-carboxylate. 1983 Prostaglandins pmid:6316421
Tolman EL and Fuller BL Inhibition of thromboxane synthesis in guinea pig lung and human platelets by clotrimazole and other imidazole antifungals. 1983 Biochem. Pharmacol. pmid:6316985
Stimler NP and O'Flaherty JT Spasmogenic properties of platelet-activating factor: evidence for a direct mechanism in the contractile response of pulmonary tissues. 1983 Am. J. Pathol. pmid:6624879
Bloch MH et al. Prostaglandin production by the pregnant and non-pregnant rabbit uterus. 1983 Prostaglandins pmid:6415760
McDaniel HG et al. Platelet function abnormalities in response to arachidonic acid in the acute phase of myocardial infarction. 1983 Am. J. Cardiol. pmid:6416046
Williams GA et al. Prostacyclin and thromboxane A2 derivatives in rhegmatogenous subretinal fluid. 1983 Arch. Ophthalmol. pmid:6338873
Ylikorkala O et al. Effect of vacuum curettage on the concentrations of plasma 6-keto-prostaglandin F1 alpha and serum thromboxane B2. 1983 Br J Obstet Gynaecol pmid:6338904
Marcella JJ et al. Exercise-induced myocardial ischemia in patients with coronary artery disease: lack of evidence for platelet activation or fibrin formation in peripheral venous blood. 1983 J. Am. Coll. Cardiol. pmid:6339591
Brox JH et al. Effects of cod liver oil on platelets and coagulation in familial hypercholesterolemia (type IIa). 1983 Acta Med Scand pmid:6340424
Mest HJ et al. The influence of linseed oil diet on fatty acid pattern in phospholipids and thromboxane formation in platelets in man. 1983 Klin. Wochenschr. pmid:6341702
Hartung HP et al. Stimulation of prostaglandin E and thromboxane synthesis in macrophages by purified C3b. 1983 J. Immunol. pmid:6343486
Deckmyn H et al. Prostacyclin production by whole blood from children: impairment in the hemolytic uremic syndrome and excessive formation in chronic renal failure. 1983 Thromb. Res. pmid:6344317
Ylikorkala O and Viinikka L Prostaglandins and endometriosis. 1983 Acta Obstet Gynecol Scand Suppl pmid:6344540
Ylikorkala O Prostacyclin and thromboxane during human pregnancy. 1983 Acta Obstet Gynecol Scand Suppl pmid:6344543
Qvist R and Larkins RG Diminished production of thromboxane B2 and prostaglandin E by stimulated polymorphonuclear leukocytes from insulin-treated diabetic subjects. 1983 Diabetes pmid:6345241
Newman JH et al. Effects of 100% oxygen on lung vascular function in awake sheep. 1983 J Appl Physiol Respir Environ Exerc Physiol pmid:6345493
Eldor A et al. Effects of dipyrone on prostaglandin production by human platelets and cultured bovine aortic endothelial cells. 1983 Thromb. Haemost. pmid:6346571
Sheng WY et al. Kinetic comparison and regulation of the cascade of microsomal enzymes involved in renal arachidonate and endoperoxide metabolism. 1983 J. Biol. Chem. pmid:6401732
Menys VC and Davies JA Selective inhibition of thromboxane synthetase with dazoxiben - basis of its inhibitory effect on platelet adhesion. 1983 Thromb. Haemost. pmid:6346575
Chetty N and Bradlow BA The effects of a vegetarian diet on platelet function and fatty acids. 1983 Thromb. Res. pmid:6612688
Ujiie A et al. [Studies on the inhibitory effect of etafenone hydrochloride on platelet aggregation]. 1983 Nippon Yakurigaku Zasshi pmid:6618341
Kawaguchi H Thromboxane synthesis in hypercholesterolemic platelets--on the mechanism of increased thromboxane synthesis. 1983 Hokkaido Igaku Zasshi pmid:6618425
Dubin NH et al. Thromboxane production in the pregnant rat: differential recovery by platelets and uterus following aspirin administration. 1983 Biol. Reprod. pmid:6626652
Nuotto E et al. Effect of acetylsalicylic acid on plasma thromboxane B2 and platelet aggregation in man. 1983 Eur. J. Clin. Pharmacol. pmid:6628518
Kiff PS et al. Haemodynamic and metabolic effects of dazoxiben at rest and during atrial pacing. 1983 Br J Clin Pharmacol pmid:6681708
Hutton I et al. Effects of dazoxiben on transcardiac thromboxane levels and haemodynamics in coronary heart disease. 1983 Br J Clin Pharmacol pmid:6681709
Feddersen CO et al. Leukotriene E4 causes pulmonary vasoconstriction, not inhibited by meclofenamate. 1983 Prostaglandins pmid:6098932
Socini A et al. Fish oil administration lowers prostacyclin production and the antiaggregatory activity of aortic walls more effectively than platelet aggregation and thromboxane in the rat. 1983 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:6221591
Hornstra G et al. Dietary-fat-induced changes in the formation of prostanoids of the 2 and 3 series in relation to arterial thrombosis (rat) and atherosclerosis (rabbit). 1983 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:6221593
Tremoli E et al. North Karelian study: changes in dietary fat reduce thromboxane B2 formation by platelets only in male subjects--preliminary report. 1983 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:6221594
Basso N et al. Gastric mucosal prostaglandin generation in rats with stress ulcer. 1983 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:6221618
Abiko Y et al. The stimulation of macrophage prostaglandin E2 and thromboxane B2 secretion by Streptococcus mutans insoluble glucans. 1983 FEBS Lett. pmid:6403385
Foegh M et al. Prostacyclin and thromboxane release from human peritoneal macrophages. 1983 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:6221630
Westwick J et al. Inhibition of thromboxane formation prevents endotoxin-induced renal fibrin deposition in jaundiced rats. 1983 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:6221642
Morita I et al. Stimulation of eicosapentaenoic acid metabolism in washed human platelets by 12-hydroperoxyeicosatetraenoic acid. 1983 J. Biol. Chem. pmid:6309794
Sakamoto T [Studies on platelet function in toxemia of pregnancy]. 1983 Nippon Sanka Fujinka Gakkai Zasshi pmid:6223964
Gordon PR et al. Platelet arachidonate metabolism and platelet function in zinc-deficient rats. 1983 J. Nutr. pmid:6403678
Winchester JF et al. Early indicators of renal allograft rejection. 1983 Kidney Int. Suppl. pmid:6224041
Okegawa T et al. Endotoxin induces chronic prostaglandin and thromboxane synthesis from ureter-obstructed kidneys: role of inflammatory cells. 1983 J. Pharmacol. Exp. Ther. pmid:6403696
Westwick J et al. Platelet activation during steady state sickle cell disease. 1983 J Med pmid:6224876
Ellsworth ML et al. Pulmonary prostacyclin production with increased flow and sympathetic stimulation. 1983 J Appl Physiol Respir Environ Exerc Physiol pmid:6415017
Dahl ML et al. Sodium salicylate interferes with the inhibitory effects of aspirin and indomethacin on human platelets. 1983 Prostaglandins Leukot Med pmid:6415666
Han P et al. Verapamil and collagen-induced platelet reactions--evidence for a role for intracellular calcium in platelet activation. 1983 Thromb. Haemost. pmid:6415847
Barnhart MI et al. DDAVP: does the drug have a direct effect on the vessel wall? 1983 Thromb. Res. pmid:6415852
Wallis RB Mechanisms of action of sulphinpyrazone. 1983 Thromb. Res. Suppl. pmid:6415857
Saldeen P and Saldeen T 6-keto-prostaglandin F1 alpha/thromboxane B2 ratio in vascular and lung tissue. 1983 Thromb. Res. pmid:6688484
Di Minno G et al. Monitoring the entry of new platelets into the circulation after ingestion of aspirin. 1983 Blood pmid:6404326
Wilson TW Responses to furosemide in normotensive and hypertensive subjects. 1983 Clin. Pharmacol. Ther. pmid:6688772
Gurtner GH et al. Oxidant- and lipid-induced pulmonary vasoconstriction mediated by arachidonic acid metabolites. 1983 J Appl Physiol Respir Environ Exerc Physiol pmid:6688802
van Rijk GL et al. Long-term myocardial preservation: thromboxane production and coronary resistance. 1983 J. Surg. Res. pmid:6688844
Miller JB et al. Alterations in plasma and tissue prostaglandin levels in rabbits during luteal regression. 1983 Biol. Reprod. pmid:6688954
Hidaka T et al. Thromboxane formation from arachidonic acid and prostaglandin H2 in rabbit spleen. 1983 J. Biochem. pmid:6404897
Davì G et al. The effect of two low doses of aspirin on whole blood thromboxane and prostacyclin generation in healthy subjects. 1983 Thromb. Haemost. pmid:6417815
Muccitelli RM et al. Effect of inhibition of thromboxane production on the leukotriene D4-mediated bronchoconstriction in the guinea pig. 1983 Prostaglandins pmid:6689082
Gerozissis K and Dray F In-vitro prostanoid production by the rat vas deferens. 1983 J. Reprod. Fertil. pmid:6572721
Dale J et al. The effect of a thromboxane synthetase inhibitor, dazoxiben, and acetylsalicylic acid on platelet function and prostaglandin metabolism. 1983 Thromb. Haemost. pmid:6689091
Schleimer RP et al. Effects of dexamethasone on mediator release from human lung fragments and purified human lung mast cells. 1983 J. Clin. Invest. pmid:6134755
Liu J [Effect of Paeonia obovata 801 on metabolism of thromboxane B2 and arachidonic acid and on platelet aggregation in patients with coronary heart disease and cerebral thrombosis]. 1983 Zhonghua Yi Xue Za Zhi pmid:6418338
Aehringhaus U et al. Effect of inhibition of synthesis and receptor antagonism of SRS-A in cardiac anaphylaxis. 1983 Br. J. Pharmacol. pmid:6689134
Kurata M [Relation between mouse peritoneal macrophage functions and prostaglandins]. 1983 Rinsho Byori pmid:6689184
Maguire ED and Wallis RB In vivo redirection of prostaglandin endoperoxides into 6-keto PGF1 alpha formation by thromboxane synthetase inhibitors in the rat. 1983 Thromb. Res. pmid:6689221
McDonald JW and Ali M Recovery of cyclooxygenase activity after aspirin in populations of platelets separated on stractan density gradients. 1983 Prostaglandins Leukot Med pmid:6419234
Zijlstra FJ and Vincent JE Comparison of the determination of thromboxane A2 by bioassay on the rabbit mesenteric artery and in the form of TxB2 by radioimmunoassay. 1983 J Pharmacol Methods pmid:6632924
Bryant RW and Hwang DH Development of a radioimmunoassay for 15-HETE and its application to 15-HETE production by reticulocytes. 1983 Prostaglandins pmid:6419285
Wilson L Effects of estradiol and progesterone on uterine prostaglandin levels in the pregnant rat. 1983 Prostaglandins pmid:6635211
Chong KP et al. Vasopressin stimulates thromboxane synthesis in isolated hamster hepatocytes: relation to hepatocyte calcium content. 1983 Prostaglandins pmid:6419286
Karmali RA et al. Prostaglandins in breast cancer: relationship to disease stage and hormone status. 1983 Br. J. Cancer pmid:6416285
Hartung HP et al. Induction of thromboxane release from macrophages by anaphylatoxic peptide C3a of complement and synthetic hexapeptide C3a 72-77. 1983 J. Immunol. pmid:6600482
Sautebin L et al. Preferential utilization of endogenous arachidonate by cyclo-oxygenase in incubations of human platelets. 1983 FEBS Lett. pmid:6407867
Zipser RD et al. Urinary thromboxane B2 and prostaglandin E2 in the hepatorenal syndrome: evidence for increased vasoconstrictor and decreased vasodilator factors. 1983 Gastroenterology pmid:6572162
Schenkelaars EJ and Bonta IL Effect of leukotriene C4 on the release of secretory products by elicited populations of rat peritoneal macrophages. 1983 Eur. J. Pharmacol. pmid:6572592
Rocklin RE et al. Augmentation of prostaglandin and thromboxane production in vitro by monocytes exposed to histamine-induced suppressor factor (HSF). 1983 Cell. Immunol. pmid:6573232
Ouwendijk RJ et al. Raised plasma thromboxane B2 levels in alcoholic liver disease. 1983 Prostaglandins Leukot Med pmid:6573682
Hornych A et al. Thromboxane B2 in borderline and essential hypertensive patients. 1983 Prostaglandins Leukot Med pmid:6573683
Flynn JT et al. Effects of anesthesia and surgery on prostanoid concentrations in plasma and pulmonary lymph. 1983 Prostaglandins Leukot Med pmid:6573688
Patel K and Bakhle YS Thromboxane B2 (TxB2) metabolism in rat isolated lung and its inhibition by drugs. 1983 Prostaglandins Leukot Med pmid:6573689
Hoult JR and Robinson C Selective inhibition of thromboxane B2 accumulation and metabolism in perfused guinea-pig lung. 1983 Br. J. Pharmacol. pmid:6824820
Hirsh PD et al. Effects of provocation on transcardiac thromboxane in patients with coronary artery disease. 1983 Am. J. Cardiol. pmid:6829431
Walinsky P et al. Beneficial effects of ibuprofen in pacing-induced myocardial ischemia. 1983 Am. J. Cardiol. pmid:6829434
Gimenez T et al. Fetal-maternal secretion of prostaglandins in the cow. 1983 Prostaglandins pmid:6576447
Lewy RI Role of thromboxanes in vasotonic versus vaso-occlusive angina. 1983 Arch Mal Coeur Vaiss pmid:6407435
Hayashi Y et al. Enzyme immunoassay of thromboxane B2. 1983 Biochim. Biophys. Acta pmid:6407530
Poyser NL and Brydon LJ Prostaglandin release from the guinea-pig uterus superfused in vitro. Effect of stage of estrous cycle, progesterone, estradiol, oxytocin and A23187. 1983 Prostaglandins pmid:6408712
Laitinen O et al. Plasma levels and urinary excretion of prostaglandins in patients with rheumatoid arthritis. 1983 Clin. Rheumatol. pmid:6589104
Ouwendijk RJ et al. Raised plasma levels of thromboxane B2 in systemic mastocytosis. 1983 Eur. J. Clin. Invest. pmid:6409646
Snapper JR et al. Effects of cyclooxygenase inhibitors on the alterations in lung mechanics caused by endotoxemia in the unanesthetized sheep. 1983 J. Clin. Invest. pmid:6409930