| MeSH term | MeSH ID | Detail |
|---|---|---|
| Angina Pectoris | D000787 | 27 associated lipids |
| Angina Pectoris, Variant | D000788 | 3 associated lipids |
| Angina, Unstable | D000789 | 14 associated lipids |
| Hypoxia | D000860 | 23 associated lipids |
| Aortic Aneurysm | D001014 | 8 associated lipids |
| Aortic Arch Syndromes | D001015 | 2 associated lipids |
| Aortic Rupture | D001019 | 3 associated lipids |
| Arrhythmias, Cardiac | D001145 | 42 associated lipids |
| Arterial Occlusive Diseases | D001157 | 12 associated lipids |
| Arteriosclerosis | D001161 | 86 associated lipids |
Thromboxane b2
Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
Cross Reference
Introduction
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Thromboxane b2?
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Thromboxane b2
PubChem Associated disorders and diseases
What pathways are associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Thromboxane b2?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Thromboxane b2?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
What genes are associated with Thromboxane b2?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Thromboxane b2
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Weiss K | [Calcium antagonists: anti-atherosclerotic effect by modification of the prostaglandin system]. | 1988 | Wien. Klin. Wochenschr. | pmid:3071922 |
| Kaliman J et al. | [Venous prostacycline synthesis and plasma thromboxane B2 after low-dose aspirin]. | 1983 | Wien. Klin. Wochenschr. | pmid:6359724 |
| Sinzinger H and Firbas W | [Cells of the vascular wall synthesize thromboxane]. | 1983 | Wien. Klin. Wochenschr. | pmid:6369802 |
| di Minno G et al. | The binding of fibrinogen to platelets in diabetes mellitus. | 1986 | Wien. Klin. Wochenschr. | pmid:3010580 |
| Oettinger W et al. | [Thromboxane A2 and granulocyte elastase after severe trauma--relationship to complications and survival rates]. | 1989 | Wien. Klin. Wochenschr. | pmid:2609665 |
| Gorczynska E et al. | [Effect of various stimulators on cyclooxygenase activity, platelet aggregation and TxB2 synthesis after using a platelet inhibitor (Aspro Clear) in vivo and in vitro]. | 1985 | Wiad. Lek. | pmid:3933184 |
| Glushko LV et al. | [An evaluation of the efficacy of antiatherosclerotic agents based on a study of the peripheral blood monocytes]. | 1990 | Vrach Delo | pmid:2168603 |
| Efimov VV and LadnyÄ AI | [Status of the prostacyclin and thromboxane system, lipid metabolism and lipid peroxidation processes in patients with coronary atherosclerosis]. | 1986 | Vrach Delo | pmid:3754994 |
| Aliavi AL | [Thrombocyte function and the prostacyclin-thromboxane system in patients with acute myocardial infarct]. | 1988 | Vrach Delo | pmid:3293319 |
| Bagdasarian A et al. | IVIG adverse reactions: potential role of cytokines and vasoactive substances. | 1998 | Vox Sang. | pmid:9501404 |
| Jacobi K et al. | Plasma levels of eicosanoids after transfusion of intraoperatively salvaged blood. | 2000 | Vox Sang. | pmid:10729809 |
| Bassalyk LS et al. | [The effect of indomethacin and leukinferon on the thromboxane B2 level in the blood plasma of patients with endometrial cancer in the perioperative period]. | 1992 | Vopr Onkol | pmid:1300754 |
| Malý J et al. | [Changes in platelet function in patients with arterial hypertension]. | 1995 | Vnitr Lek | pmid:7571480 |
| Spinarová L et al. | [Physical training in patients with chornic heart failure: haemodynamics, effects]. | 2001 | Vnitr Lek | pmid:15635849 |
| Margolis JH et al. | The efficacy of dexamethasone and flunixin meglumine in treating endotoxin-induced changes in calves. | 1987 | Vet. Res. Commun. | pmid:3445446 |
| Atroshi F et al. | Inflammation-related changes in cyclic AMP and cyclic GMP in bovine mastitis. | 1989 | Vet. Res. Commun. | pmid:2561035 |
| Cheng Z et al. | Pharmacokinetic and pharmacodynamic studies on phenylbutazone and oxyphenbutazone in goats. | 1997 | Vet. Rec. | pmid:9123796 |
| Friton GM et al. | Clinical and anti-inflammatory effects of treating endotoxin-challenged pigs with meloxicam. | 2006 | Vet. Rec. | pmid:17056651 |
| McKellar QA et al. | Flunixin pharmacokinetics and serum thromboxane inhibition in the dog. | 1989 | Vet. Rec. | pmid:2763429 |
| Galbraith EA and McKellar QA | Pharmacokinetics and pharmacodynamics of piroxicam in dogs. | 1991 | Vet. Rec. | pmid:1887556 |
| Mustonen K et al. | Dose-response investigation of oral ketoprofen in pigs challenged with Escherichia coli endotoxin. | 2012 | Vet. Rec. | pmid:22735989 |
| Banting A et al. | Efficacy of oral and parenteral ketoprofen in lactating cows with endotoxin-induced acute mastitis. | 2008 | Vet. Rec. | pmid:18953074 |
| Taylor PM et al. | Pharmacodynamics and pharmacokinetics of flunixin in the cat: a preliminary study. | 1991 | Vet. Rec. | pmid:2035219 |
| Giri SN et al. | Effects of endotoxin infusion on circulating levels of eicosanoids, progesterone, cortisol, glucose and lactic acid, and abortion in pregnant cows. | 1990 | Vet. Microbiol. | pmid:2407024 |
| Van de Weerdt ML et al. | Ketoprofen and phenylbutazone attenuation of PAF-induced lung inflammation in calves. | 1999 | Vet. J. | pmid:10030127 |
| Lees P et al. | Pharmacodynamics and pharmacokinetics of tolfenamic acid in ruminating calves: evaluation in models of acute inflammation. | 1998 | Vet. J. | pmid:9638074 |
| Maddens BE et al. | Validation of immunoassays for the candidate renal markers C-reactive protein, immunoglobulin G, thromboxane B2 and retinol binding protein in canine urine. | 2010 | Vet. Immunol. Immunopathol. | pmid:19815297 |
| Hall JA et al. | Dietary fish oil alters the lysophospholipid metabolomic profile and decreases urinary 11-dehydro thromboxane Bâ‚‚ concentration in healthy Beagles. | 2011 | Vet. Immunol. Immunopathol. | pmid:21925741 |
| Sigel MM et al. | Phylogenetic studies on lymphokines. Fish lymphocytes respond to human IL-1 and epithelial cells produce an IL-1 like factor. | 1986 | Vet. Immunol. Immunopathol. | pmid:3490047 |
| Peters SM et al. | In vivo characterization of inflammatory biomarkers in swine and the impact of flunixin meglumine administration. | 2012 | Vet. Immunol. Immunopathol. | pmid:22648045 |
| Bailey SR et al. | Plasma concentrations of endotoxin and platelet activation in the developmental stage of oligofructose-induced laminitis. | 2009 | Vet. Immunol. Immunopathol. | pmid:19091426 |
| Moore RM et al. | Effect of platelet-activating factor antagonist L-691,880 on low-flow ischemia-reperfusion injury of the large colon in horses. | 1998 Jan-Feb | Vet Surg | pmid:9449176 |
| Higgins AJ et al. | Actions of BW540C in an equine model of acute inflammation: a preliminary study. | 1987 | Vet Q | pmid:3039716 |
| Dinev D and Andonova M | The effect of general anesthesia and abdominal surgery upon plasma thromboxane B concentrations in horses. | 2004 | Vet Anaesth Analg | pmid:15053753 |
| Mullins KB et al. | Effects of carprofen, meloxicam and deracoxib on platelet function in dogs. | 2012 | Vet Anaesth Analg | pmid:22248445 |
| Brezitskaia ON and Sedov KR | [Status of the thrombocytic-vascular component of the hemostasis system in the population of the Far North]. | 1991 | Vestn. Akad. Med. Nauk SSSR | pmid:1801462 |
| Polkanov VS and Vinogradov AI | [The content of thromboxane B2 and 6-ketoprostaglandin F1 alpha of the blood plasma in patients with psoriasis and children with allergic dermatoses]. | 1989 | Vestn Dermatol Venerol | pmid:2718610 |
| Zhou Z et al. | Mechanisms underlying uridine adenosine tetraphosphate-induced vascular contraction in mouse aorta: Role of thromboxane and purinergic receptors. | 2015 | Vascul. Pharmacol. | pmid:25921923 |
| Miyamoto A et al. | Ibuprofen or ozagrel increases NO release and l-nitro arginine induces TXA(2) release from cultured porcine basilar arterial endothelial cells. | 2007 | Vascul. Pharmacol. | pmid:17113355 |
| González-Correa JA et al. | Gender differences in the effect of aspirin on retinal ischemia, prostanoid synthesis and nitric oxide production in experimental type 1-like diabetes. | 2007 Aug-Sep | Vascul. Pharmacol. | pmid:17581795 |
| Park WH et al. | Anti-inflammatory effects of a traditional Korean herbal formulation, Silsosangami, consisting of seven medicinal herbs: effect on hemolysis, neutrophil function, and gene expressions of iNOS and COX-2. | 2004 | Vascul. Pharmacol. | pmid:15664882 |
| Sinzinger H et al. | 20 mg aspirin daily--evidence for a clinical future of this extremely low-dose in arterial disease? | 1988 | VASA | pmid:3369232 |
| Strobl-Jäger E et al. | Platelet half-life in comparison to other in-vivo platelet function parameters such as thromboxane B2, beta-thromboglobulin and platelet factor 4 in patients with atherosclerotic lesions with and without hyperlipoproteinemia. | 1986 | VASA | pmid:2948337 |
| Ditter H and Matthias FR | Changes in thromboxane formation by platelets during and after a continuous endotoxin infusion into rabbits. | 1984 | VASA | pmid:6516562 |
| Fitscha P et al. | Follow-up of in-vivo platelet function (platelet half-life, thromboxane B2) in patients with coronary heart disease. | 1984 | VASA | pmid:6516563 |
| Rebrov BA | [Role of thromboxane A2 (B2) in the pathogenesis of stress proteinuria in healthy persons]. | 2001 Mar-Apr | Urologiia | pmid:11490711 |
| Frøkiaer J et al. | Renal blood flow and pelvic pressure after 4 weeks of total upper urinary tract obstruction in the pig. The effect of a TxA2 synthetase inhibitor on active preglomerular vasoconstriction. | 1988 | Urol. Res. | pmid:3413908 |
| Ali M et al. | Urothelial synthesis of prostanoids in the ovine ureter. | 1998 | Urol. Res. | pmid:9694598 |
| Greenstein A et al. | The role of oxygen free radicals and prostaglandins in reperfusion injury to warm ischemic kidneys. | 1991 | Urol. Res. | pmid:1759334 |
| RogovyÄ IuE | [Beta 2-microglobulin as a criterion of dysfunction in the regulation of proximal tubular activity in mercuric chloride-induced nephropathy]. | 1998 May-Jun | Urol Nefrol (Mosk) | pmid:9644989 |