Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Hypoxia-Ischemia, Brain D020925 22 associated lipids
Stroke D020521 32 associated lipids
Latex Hypersensitivity D020315 1 associated lipids
Intracranial Hemorrhage, Hypertensive D020299 1 associated lipids
Ventricular Remodeling D020257 28 associated lipids
Venous Thrombosis D020246 11 associated lipids
Infarction, Middle Cerebral Artery D020244 35 associated lipids
Carotid Artery Injuries D020212 8 associated lipids
Sleep Apnea, Obstructive D020181 9 associated lipids
Basal Ganglia Hemorrhage D020145 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

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Authors Title Published Journal PubMed Link
Gross GJ and Moore J Effect of COX-1/COX-2 inhibition versus selective COX-2 inhibition on coronary vasodilator responses to arachidonic acid and acetylcholine. 2004 Pharmacology pmid:15161995
Dey A et al. Altered kidney CYP2C and cyclooxygenase-2 levels are associated with obesity-related albuminuria. 2004 Obes. Res. pmid:15340111
Sheu JR et al. Expression of matrix metalloproteinase-9 in human platelets: regulation of platelet activation in in vitro and in vivo studies. 2004 Br. J. Pharmacol. pmid:15289295
Toth B et al. Insights into the role of interleukin-6 in the induction of hepatic injury after trauma-hemorrhagic shock. 2004 J. Appl. Physiol. pmid:15298985
Craft JA et al. Increased platelet-derived microparticles in the coronary circulation of percutaneous transluminal coronary angioplasty patients. 2004 Blood Coagul. Fibrinolysis pmid:15311156
Ferroni P et al. Platelet activation in type 2 diabetes mellitus. 2004 J. Thromb. Haemost. pmid:15304032
Torsney E et al. Thrombosis and neointima formation in vein grafts are inhibited by locally applied aspirin through endothelial protection. 2004 Circ. Res. pmid:15117816
Wang YY et al. Inhibition of platelet aggregation by polyaspartoyl L-arginine and its mechanism. 2004 Acta Pharmacol. Sin. pmid:15066215
Park HS et al. Dietary conjugated linoleic acid increases the mRNA ratio of Bax/Bcl-2 in the colonic mucosa of rats. 2004 J. Nutr. Biochem. pmid:15068816
Zhang C et al. Inhibition of inflammation contributes to organ protection of atenolol in sinoaortic-denervated rats. 2004 J. Cardiovasc. Pharmacol. pmid:15071353
Bruno A et al. Serial urinary 11-dehydrothromboxane B2, aspirin dose, and vascular events in blacks after recent cerebral infarction. 2004 Stroke pmid:14963281
Kwak SH et al. Effects of propofol on endotoxin-induced acute lung injury in rabbit. 2004 J. Korean Med. Sci. pmid:14966342
Scott G et al. Lumiracoxib: pharmacokinetic and pharmacodynamic profile when coadministered with fluconazole in healthy subjects. 2004 J Clin Pharmacol pmid:14747429
Park WH et al. Anti-inflammatory effects of a traditional Korean herbal formulation, Silsosangami, consisting of seven medicinal herbs: effect on hemolysis, neutrophil function, and gene expressions of iNOS and COX-2. 2004 Vascul. Pharmacol. pmid:15664882
Vainio M et al. Prostacyclin, thromboxane A and the effect of low-dose ASA in pregnancies at high risk for hypertensive disorders. 2004 Acta Obstet Gynecol Scand pmid:15548142
Tsai CY et al. Proinflammatory cytokines enhance COX-1 gene expression in cultured rat glomerular mesangial cells. 2004 Int. Immunopharmacol. pmid:14975359
Smalling WE et al. Protective effect of pentoxifylline on volume-induced lung injury in newborn piglets. 2004 Biol. Neonate pmid:14981352
Tanigawa T et al. Anti-inflammatory effect of two isoforms of COX in H. pylori-induced gastritis in mice: possible involvement of PGE2. 2004 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:12958020
Park WH et al. Inhibitory effect of GBH on platelet aggregation through inhibition of intracellular Ca2+ mobilization in activated human platelets. 2004 Life Sci. pmid:15474558
Chen BN et al. [Characteristic changes of vascular tension factors in diabetic arterial occlusion of lower extremities]. 2004 Zhongguo Zhong Xi Yi Jie He Za Zhi pmid:15495823
Horani MH et al. Cyclooxygenase inhibition is associated with downregulation of apolipoprotein AI promoter activity in cultured hepatoma cell line HepG2. 2004 Metab. Clin. Exp. pmid:14767868
Peck OM et al. Staphylococcus aureus and lipopolysaccharide induce homologous tolerance but heterologous priming: role of interferon-gamma. 2004 Shock pmid:14770039
Kawata K et al. The effects of a selective cyclooxygenase-2 inhibitor on small bowel ischemia-reperfusion injury. 2003 Nov-Dec Hepatogastroenterology pmid:14696445
Tuleja E et al. Effects of cyclooxygenases inhibitors on vasoactive prostanoids and thrombin generation at the site of microvascular injury in healthy men. 2003 Arterioscler. Thromb. Vasc. Biol. pmid:12730088
Leese PT et al. The COX-2 selective inhibitor, valdecoxib, does not impair platelet function in the elderly: results of a randomized controlled trial. 2003 J Clin Pharmacol pmid:12751271
Lang I et al. Heterogeneity of microvascular endothelial cells isolated from human term placenta and macrovascular umbilical vein endothelial cells. 2003 Eur. J. Cell Biol. pmid:12751902
Molina V et al. Synergistic effect of D-003 and aspirin on experimental thrombosis models. 2003 Prostaglandins Leukot. Essent. Fatty Acids pmid:12711246
Chavarría ME et al. Prostacyclin/thromboxane early changes in pregnancies that are complicated by preeclampsia. 2003 Am. J. Obstet. Gynecol. pmid:12712098
Dogné JM et al. Pharmacological evaluation of the novel thromboxane modulator BM-567 (I/II). Effects of BM-567 on platelet function. 2003 Prostaglandins Leukot. Essent. Fatty Acids pmid:12538090
Tanaka S et al. High dose of inhaled fluticasone reduces high levels of urinary leukotriene E4 in the early morning in mild and moderate nocturnal asthma. 2003 Chest pmid:14605047
Reid G et al. The human multidrug resistance protein MRP4 functions as a prostaglandin efflux transporter and is inhibited by nonsteroidal antiinflammatory drugs. 2003 Proc. Natl. Acad. Sci. U.S.A. pmid:12835412
Vass G et al. Comparison of nasal and oral inhalation during exhaled breath condensate collection. 2003 Am. J. Respir. Crit. Care Med. pmid:12493648
Sidhu P et al. Tissue chamber model of acute inflammation in farm animal species. 2003 Res. Vet. Sci. pmid:12507568
Xia Z et al. Antioxidant therapy with Salvia miltiorrhiza decreases plasma endothelin-1 and thromboxane B2 after cardiopulmonary bypass in patients with congenital heart disease. 2003 J. Thorac. Cardiovasc. Surg. pmid:14666012
Rossoni G et al. Nitric oxide-releasing aspirin inhibits vasoconstriction in perfused tail artery of normotensive and spontaneously hypertensive rats. 2003 Eur. J. Pharmacol. pmid:14512099
Yokoyama Y et al. Role of thromboxane in producing portal hypertension following trauma-hemorrhage. 2003 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:14613921
Yi H et al. [Protective effect of selective cyclooxygenase-2 inhibitor on alcohol-induced liver injury in rats]. 2003 Zhonghua Gan Zang Bing Za Zhi pmid:14636441
Sánchez-Muniz FJ et al. Platelet aggregation, thromboxane production and thrombogenic ratio in postmenopausal women consuming high oleic acid-sunflower oil or palmolein. 2003 Eur J Nutr pmid:14673602
Gu L et al. [Advances in the study on molecular mechanism of diabetic nephropathy treated with Rheum officinale]. 2003 Zhongguo Zhong Yao Za Zhi pmid:15224660
De Cristofaro R et al. Lipid and protein oxidation contribute to a prothrombotic state in patients with type 2 diabetes mellitus. 2003 J. Thromb. Haemost. pmid:12871497
Al-Madaney MM et al. Effects of lipid-esterified conjugated linoleic acid isomers on platelet function: evidence for stimulation of platelet phospholipase activity. 2003 Biochim. Biophys. Acta pmid:14729070
Fujii S et al. L-arginine reverses p47phox and gp91phox expression induced by high salt in Dahl rats. 2003 Hypertension pmid:14504257
De León EJ et al. A new chloroquinolinyl chalcone derivative as inhibitor of inflammatory and immune response in mice and rats. 2003 J. Pharm. Pharmacol. pmid:14604476
Dong WG et al. Ameliorative effects of sodium ferulate on experimental colitis and their mechanisms in rats. 2003 World J. Gastroenterol. pmid:14606091
Wolfram RM et al. Narghile (water pipe) smoking influences platelet function and (iso-)eicosanoids. 2003 Life Sci. pmid:14575812
Seebacher F and Franklin CE Prostaglandins are important in thermoregulation of a reptile (Pogona vitticeps). 2003 Proc. Biol. Sci. pmid:12952634
Yokoyama Y et al. Role of thromboxane A2 in early BDL-induced portal hypertension. 2003 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:12431905
Tsipas G and Morphake P Beneficial effects of a diet rich in a mixture of n - 6/n - 3 essential fatty acids and of their metabolites on cyclosporine - nephrotoxicity. 2003 J. Nutr. Biochem. pmid:14629893
Arifah AK et al. Pharmacodynamics, chiral pharmacokinetics and PK-PD modelling of ketoprofen in the goat. 2003 J. Vet. Pharmacol. Ther. pmid:12667184
Ji Y et al. Thrombosis and its significance after experimental pulmonary thromboembolism. 2003 Chin. Med. J. pmid:12667387