Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

Cross Reference

Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Hypoxia-Ischemia, Brain D020925 22 associated lipids
Stroke D020521 32 associated lipids
Latex Hypersensitivity D020315 1 associated lipids
Intracranial Hemorrhage, Hypertensive D020299 1 associated lipids
Ventricular Remodeling D020257 28 associated lipids
Venous Thrombosis D020246 11 associated lipids
Infarction, Middle Cerebral Artery D020244 35 associated lipids
Carotid Artery Injuries D020212 8 associated lipids
Sleep Apnea, Obstructive D020181 9 associated lipids
Basal Ganglia Hemorrhage D020145 1 associated lipids
Per page 10 20 50 100 | Total 293

PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

Download all related citations
Per page 10 20 50 100 | Total 6367
Authors Title Published Journal PubMed Link
Gao XR et al. Efficacy of different doses of aspirin in decreasing blood levels of inflammatory markers in patients with cardiovascular metabolic syndrome. 2009 J. Pharm. Pharmacol. pmid:19903376
Zuo Y et al. Gross-total hematoma removal of hypertensive basal ganglia hemorrhages: a long-term follow-up. 2009 J. Neurol. Sci. pmid:19801153
Frelinger AL et al. Association of cyclooxygenase-1-dependent and -independent platelet function assays with adverse clinical outcomes in aspirin-treated patients presenting for cardiac catheterization. 2009 Circulation pmid:19996015
Kambara T et al. Propofol suppresses prostaglandin E(2) production in human peripheral monocytes. 2009 Immunopharmacol Immunotoxicol pmid:19951072
Hu Y et al. Chinese herbal medicinal ingredients inhibit secretion of IL-6, IL-8, E-selectin and TXB2 in LPS-induced rat intestinal microvascular endothelial cells. 2009 Immunopharmacol Immunotoxicol pmid:19874221
Dietrich-Muszalska A and Olas B Isoprostenes as indicators of oxidative stress in schizophrenia. 2009 World J. Biol. Psychiatry pmid:19673085
Stanke-Labesque F et al. Increased urinary leukotriene E4 excretion in obstructive sleep apnea: effects of obesity and hypoxia. 2009 J. Allergy Clin. Immunol. pmid:19596146
Coates AM et al. Regular consumption of n-3 fatty acid-enriched pork modifies cardiovascular risk factors. 2009 Br. J. Nutr. pmid:18590592
Hynninen VV et al. Oral voriconazole and miconazole oral gel produce comparable effects on the pharmacokinetics and pharmacodynamics of etoricoxib. 2009 Eur. J. Clin. Pharmacol. pmid:18777173
Muir AR et al. Assessment of aspirin resistance varies on a temporal basis in patients with ischaemic heart disease. 2009 Heart pmid:18697805
Foudi N et al. Selective cyclooxygenase-2 inhibition directly increases human vascular reactivity to norepinephrine during acute inflammation. 2009 Cardiovasc. Res. pmid:18952694
Rogers LK et al. Differential responses in the lungs of newborn mouse pups exposed to 85% or >95% oxygen. 2009 Pediatr. Res. pmid:18703992
Fernández-Arche A et al. Long-chain fatty alcohols from pomace olive oil modulate the release of proinflammatory mediators. 2009 J. Nutr. Biochem. pmid:18555679
Shah KB et al. The cardioprotective effects of fish oil during pressure overload are blocked by high fat intake: role of cardiac phospholipid remodeling. 2009 Hypertension pmid:19597033
Zeng HH et al. [Effect of safflower injection on pulmonary hypertension in rat during chronic hypoxia and hypercapnia]. 2009 Zhongguo Ying Yong Sheng Li Xue Za Zhi pmid:21186611
Santilli F et al. Platelet cyclooxygenase inhibition by low-dose aspirin is not reflected consistently by platelet function assays: implications for aspirin "resistance". 2009 J. Am. Coll. Cardiol. pmid:19232899
Lev EI Aspirin resistance transient laboratory finding or important clinical entity? 2009 J. Am. Coll. Cardiol. pmid:19232900
Bernoud-Hubac N et al. Low concentrations of reactive gamma-ketoaldehydes prime thromboxane-dependent human platelet aggregation via p38-MAPK activation. 2009 Biochim. Biophys. Acta pmid:19233311
Giraudel JM et al. Differential inhibition of cyclooxygenase isoenzymes in the cat by the NSAID robenacoxib. 2009 J. Vet. Pharmacol. Ther. pmid:19161453
Jespersen B et al. Differential effects of immunosuppressive drugs on COX-2 activity in vitro and in kidney transplant patients in vivo. 2009 Nephrol. Dial. Transplant. pmid:19193738
Chen SS et al. Elevated plasma prostaglandins and acetylated histone in monocytes in Type 1 diabetes patients. 2009 Diabet. Med. pmid:19236624
Kanazawa S et al. Effect of low-dose aspirin for skin rash associated with erlotinib therapy in patients with lung cancer. 2009 Platelets pmid:19172526
Calapai G et al. Cardiovascular biomarkers in groups of established smokers after a decade of smoking. 2009 Basic Clin. Pharmacol. Toxicol. pmid:19175368
Hynninen VV et al. Voriconazole increases while itraconazole decreases plasma meloxicam concentrations. 2009 Antimicrob. Agents Chemother. pmid:19015346
Kerola M et al. Effects of nimesulide, acetylsalicylic acid, ibuprofen and nabumetone on cyclooxygenase-1- and cyclooxygenase-2-mediated prostanoid production in healthy volunteers ex vivo. 2009 Basic Clin. Pharmacol. Toxicol. pmid:19152549
O'Donnell ME et al. The effects of cilostazol on exercise-induced ischaemia-reperfusion injury in patients with peripheral arterial disease. 2009 Eur J Vasc Endovasc Surg pmid:19112032
Bailey SR et al. Plasma concentrations of endotoxin and platelet activation in the developmental stage of oligofructose-induced laminitis. 2009 Vet. Immunol. Immunopathol. pmid:19091426
Dołegowska B et al. Platelets arachidonic acid metabolism in patients with essential hypertension. 2009 Platelets pmid:19440924
Ahmad M et al. Prolonged opportunity for neuroprotection in experimental stroke with selective blockade of cyclooxygenase-2 activity. 2009 Brain Res. pmid:19446533
Schuijt MP et al. The interaction of ibuprofen and diclofenac with aspirin in healthy volunteers. 2009 Br. J. Pharmacol. pmid:19466986
Eriksson AC et al. Static platelet adhesion, flow cytometry and serum TXB2 levels for monitoring platelet inhibiting treatment with ASA and clopidogrel in coronary artery disease: a randomised cross-over study. 2009 J Transl Med pmid:19508722
Cattaneo M Letter by cattaneo regarding article, "incomplete inhibition of thromboxane biosynthesis by acetylsalicylic Acid: determinants and effect on cardiovascular risk". 2009 Circulation pmid:19546394
Li L et al. The anti-inflammatory effects of ZLJ-6, a novel dual cyclooxygenase/5-lipoxygenase inhibitor. 2009 Eur. J. Pharmacol. pmid:19243697
Csányi G et al. Effects of 3-aminopyridine-induced seizures on platelet eicosanoid synthesis. 2008 May-Jun Pharmacol Rep pmid:18622059
Santilli F et al. Circulating endothelial progenitor cells and residual in vivo thromboxane biosynthesis in low-dose aspirin-treated polycythemia vera patients. 2008 Blood pmid:18541722
Yokoyama Y et al. Up-regulated thromboxane production in the rat liver with biliary obstruction does not contribute to promote hepatic injury. 2008 Shock pmid:17885643
Meen O et al. No case of COX-1-related aspirin resistance found in 289 patients with symptoms of stable CHD remitted for coronary angiography. 2008 Scand. J. Clin. Lab. Invest. pmid:17934975
Zhao S et al. Predominant basal directional release of thromboxane, but not prostacyclin, by placental trophoblasts from normal and preeclamptic pregnancies. 2008 Placenta pmid:17936899
Heistein LC et al. Aspirin resistance in children with heart disease at risk for thromboembolism: prevalence and possible mechanisms. 2008 Pediatr Cardiol pmid:17896127
Toscano CD et al. NMDA-induced seizure intensity is enhanced in COX-2 deficient mice. 2008 Neurotoxicology pmid:18834901
Lee CR et al. Cyclooxygenase polymorphisms and risk of cardiovascular events: the Atherosclerosis Risk in Communities (ARIC) study. 2008 Clin. Pharmacol. Ther. pmid:17495879
Awad H et al. Intracellular and extracellular expression of the major inducible 70kDa heat shock protein in experimental ischemia-reperfusion injury of the spinal cord. 2008 Exp. Neurol. pmid:18511046
Momen A et al. Local prostaglandin blockade attenuates muscle mechanoreflex-mediated renal vasoconstriction during muscle stretch in humans. 2008 Am. J. Physiol. Heart Circ. Physiol. pmid:18326807
Skoglund C et al. C-reactive protein and C1q regulate platelet adhesion and activation on adsorbed immunoglobulin G and albumin. 2008 Immunol. Cell Biol. pmid:18332893
Menzies D et al. Effect of aspirin on airway inflammation and pulmonary function in patients with persistent asthma. 2008 J. Allergy Clin. Immunol. pmid:18313127
Geske FJ et al. AspirinWorks: a new immunologic diagnostic test for monitoring aspirin effect. 2008 Mol Diagn Ther pmid:18288882
Selg E et al. Effects of selective and non-selective COX inhibitors on antigen-induced release of prostanoid mediators and bronchoconstriction in the isolated perfused and ventilated guinea pig lung. 2008 Prostaglandins Leukot. Essent. Fatty Acids pmid:18294831
Basselin M et al. Chronic carbamazepine administration attenuates dopamine D2-like receptor-initiated signaling via arachidonic acid in rat brain. 2008 Neurochem. Res. pmid:18302021
Eikelboom JW et al. Incomplete inhibition of thromboxane biosynthesis by acetylsalicylic acid: determinants and effect on cardiovascular risk. 2008 Circulation pmid:18838564
Banting A et al. Efficacy of oral and parenteral ketoprofen in lactating cows with endotoxin-induced acute mastitis. 2008 Vet. Rec. pmid:18953074