Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Drowning D004332 2 associated lipids
Pulmonary Heart Disease D011660 2 associated lipids
Aortic Arch Syndromes D001015 2 associated lipids
Tachycardia, Paroxysmal D013614 2 associated lipids
Mixed Connective Tissue Disease D008947 2 associated lipids
Platelet Storage Pool Deficiency D010981 3 associated lipids
Takayasu Arteritis D013625 3 associated lipids
Tachycardia, Supraventricular D013617 3 associated lipids
Pneumonia, Aspiration D011015 3 associated lipids
Infertility D007246 3 associated lipids
Macular Edema D008269 3 associated lipids
Hydatidiform Mole D006828 3 associated lipids
Yang Deficiency D016711 3 associated lipids
Aortic Rupture D001019 3 associated lipids
Hemorrhagic Fever with Renal Syndrome D006480 3 associated lipids
Bronchopulmonary Sequestration D001998 3 associated lipids
Airway Remodeling D056151 3 associated lipids
Contusions D003288 3 associated lipids
Angina Pectoris, Variant D000788 3 associated lipids
Jejunal Diseases D007579 3 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

Download all related citations
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Authors Title Published Journal PubMed Link
Lumley P et al. Maximal blockade of TxA2 without compromised PGI2 formation; a superior profile of the TxA2 receptor blocking drug GR32191 over aspirin. 1991 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:1825385
Patrono C et al. Thromboxane-dependent platelet activation as a transducer of enhanced risk of coronary and cerebral thrombosis. 1991 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:1825389
Zhao Y et al. Thromboxane and leukotriene generation by mononuclearcytes from cardiac transplant patients. 1991 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:1825392
Vial JH et al. Rebound elevation in urinary thromboxane B2 and 6-keto-PGF1 alpha excretion after aspirin withdrawal. 1991 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:1825534
Ritter JM et al. On the mechanism of the prolonged action in man of GR32191, a thromboxane receptor antagonist. 1991 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:1825568
Foegh ML et al. Eicosanoids, gamma-interferon and inflammatory cells in kidney transplant patients. 1986 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:2949550
Pedrinelli R et al. The influence of selective and nonselective prostaglandin inhibition on renin. 1985 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:3159197
Ezra D et al. Effects of platelet-activating factor on coronary hemodynamics and coronary venous plasma levels of TXB2, 6-keto-PGF1 alpha, and leukotriene C4 immunoreactivity in the intact domestic pig heart. 1985 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:3159202
Gensini GF et al. Effects of dipyridamole infusion on local platelet aggregation and local formation of thromboxane A2 in patients with pulmonary hypertension. 1985 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:3159209
De Caterina R et al. Aspirin after acute myocardial infarction: a systematic approach to compare the hemostatic effects of three different doses. 1985 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:3159210
Yamamoto S et al. Enzyme immunoassay of thromboxane B2 and 6-keto-prostaglandin F1 alpha as a substitute for radioimmunoassay. 1983 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:6221523
Weerasekera DA et al. Chemiluminescence immunoassay of thromboxane B2. 1983 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:6221524
Ito T et al. Effects of a selective inhibitor of thromboxane synthetase (OKY-1581) in humans. 1983 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:6221531
FitzGerald GA et al. Aspirin inhibits endogenous prostacyclin and thromboxane biosynthesis in man. 1983 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:6221534
van der Giessen WJ et al. Acute effect of cigarette smoking on cardiac prostaglandin synthesis and platelet behavior in patients with coronary heart disease. 1983 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:6221546
Bach MK et al. In vivo and in vitro actions of a new selective inhibitor of leukotriene C and D synthesis. 1983 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:6221551
Grose JH et al. Imbalanced prostacyclin and thromboxane A2 production in essential hypertension. 1983 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:6221555
Hornych A et al. Thromboxane B2 in borderline and essential hypertension. 1983 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:6221556
MacIntyre DE et al. Role of endogenous arachidonate metabolites in phospholipid-induced human platelet activation. 1983 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:6221557
Krishnamurthi S et al. Paradoxical effects of indomethacin and trifluoperazine on Ca2+ ionophore A23187-induced human platelet aggregation, thromboxane B2 production, and dense granule release. 1983 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:6221559