Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Heart Septal Defects D006343 2 associated lipids
Retinal Vein Occlusion D012170 2 associated lipids
Weil Disease D014895 2 associated lipids
Pulmonary Heart Disease D011660 2 associated lipids
Drowning D004332 2 associated lipids
Angina Pectoris, Variant D000788 3 associated lipids
Pneumonia, Viral D011024 3 associated lipids
Jejunal Diseases D007579 3 associated lipids
Platelet Storage Pool Deficiency D010981 3 associated lipids
Takayasu Arteritis D013625 3 associated lipids
Tachycardia, Supraventricular D013617 3 associated lipids
Pneumonia, Aspiration D011015 3 associated lipids
Infertility D007246 3 associated lipids
Hydatidiform Mole D006828 3 associated lipids
Macular Edema D008269 3 associated lipids
Hemorrhagic Fever with Renal Syndrome D006480 3 associated lipids
Yang Deficiency D016711 3 associated lipids
Aortic Rupture D001019 3 associated lipids
Contusions D003288 3 associated lipids
Bronchopulmonary Sequestration D001998 3 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

Download all related citations
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Authors Title Published Journal PubMed Link
Oosaki R et al. Urinary leukotriene E4 and 11-dehydrothromboxane B2 in patients with aspirin-sensitive asthma. 1997 Allergy pmid:9188934
Elissalde MH and Beier RC Stimulation and release of prostaglandins and thromboxane from macrophages by cotton dust associated lipopolysaccharides. 1990 Am Ind Hyg Assoc J pmid:2270833
Andersson T et al. Evaluation of the pharmacodynamics of acetylsalicylic acid 81 mg with or without esomeprazole 20 mg in healthy volunteers. 2012 Am J Cardiovasc Drugs pmid:22631032
Leese PT et al. Valdecoxib does not impair platelet function. 2002 Am J Emerg Med pmid:12098171
Jung TT and Juhn SK Prostaglandins in human cholesteatoma and granulation tissue. 1988 Am J Otol pmid:3177602
Mehta P et al. Plasma concentrations of thromboxane and prostacyclin metabolites in patients with bone tumors. 1985 Am J Pediatr Hematol Oncol pmid:2994511
Natarajan G et al. Chorioamnionitis and ontogeny of circulating prostaglandin and thromboxane in preterm infants. 2008 Am J Perinatol pmid:18726836
Brown HL et al. Plasma and amniotic fluid prostacyclin and thromboxane in mild pregnancy-induced hypertension. 1987 Am J Perinatol pmid:3566883
Satterfield S et al. Biochemical markers of compliance in the Physicians' Health Study. 1990 Sep-Oct Am J Prev Med pmid:2268456
Ingster LM and Feinleib M Salicylate intake and cardiovascular disease: Ingster and Feinleib respond to Hu and Willett. 1998 Am J Public Health pmid:9702172
Cambria RA et al. Thromboxane synthetase inhibition decreases polymorphonuclear leukocyte activation following hindlimb ischemia. 1991 Am Surg pmid:1847027
Montalescot G et al. Early thromboxane release during pacing-induced myocardial ischemia with angiographically normal coronary arteries. 1990 Am. Heart J. pmid:2248190
Smith EF and Lefer AM Stabilization of cardiac lysosomal and cellular membranes in protection of ischemic myocardium due to coronary occlusion:efficacy of the nonsteroidal anti-inflammatory agent, naproxen. 1981 Am. Heart J. pmid:7211667
Tomoda H Development of an experimental model of acute myocardial infarction and the effects of a thromboxane synthetase inhibitor (OKY-046). 1986 Am. Heart J. pmid:3532743
Walinsky P et al. Thromboxane A2 in acute myocardial infarction. 1984 Am. Heart J. pmid:6485997
De Caterina R et al. Inhibition of platelet function during in vivo infusion of isosorbide mononitrates: relationship between plasma drug concentration and hemodynamic effects. 1990 Am. Heart J. pmid:2321506
Buerke M et al. Aspirin therapy: optimized platelet inhibition with different loading and maintenance doses. 1995 Am. Heart J. pmid:7661062
O'Connor KM et al. The effect of thromboxane inhibition on vulnerability to ventricular fibrillation in the acute and chronic feline infarction models. 1989 Am. Heart J. pmid:2929400
O'Connor KM et al. Effect of thromboxane synthetase inhibition on vulnerability to ventricular arrhythmia following coronary occlusion. 1986 Am. Heart J. pmid:3953390
Austin JC et al. Thromboxane synthetase inhibition reduces ventricular irritability after coronary occlusion and reperfusion. 1988 Am. Heart J. pmid:3344655