Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Kawai VK et al. | Suboptimal inhibition of platelet cyclooxygenase 1 by aspirin in systemic lupus erythematosus: association with metabolic syndrome. | 2014 | Arthritis Care Res (Hoboken) | pmid:24022862 |
Elsheikh W et al. | Enhanced chemopreventive effects of a hydrogen sulfide-releasing anti-inflammatory drug (ATB-346) in experimental colorectal cancer. | 2014 | Nitric Oxide | pmid:24747869 |
Suarez-Kurtz G | Impact of CYP2C9*3/*3 genotype on the pharmacokinetics and pharmacodynamics of oxicam NSAIDs. | 2014 | Pharmacogenet. Genomics | pmid:25003537 |
Lee HI et al. | Response to Suarez-Kurtz's comments on strongly increased exposure of meloxicam in CYP2C9*3/*3 individuals. | 2014 | Pharmacogenet. Genomics | pmid:25003538 |
Zhu Y et al. | Effects and mechanisms of Fenofibrate on the secretion of vascular endothelial contraction factors in hypertensive rats. | 2014 | Genet. Mol. Res. | pmid:25078582 |
Hayashi G et al. | Frataxin deficiency increases cyclooxygenase 2 and prostaglandins in cell and animal models of Friedreich's ataxia. | 2014 | Hum. Mol. Genet. | pmid:25104852 |
Floyd CN et al. | Increased platelet expression of glycoprotein IIIa following aspirin treatment in aspirin-resistant but not aspirin-sensitive subjects. | 2014 | Br J Clin Pharmacol | pmid:25099258 |
Zhu SH et al. | Protective effect of indomethacin in renal ischemia-reperfusion injury in mice. | 2014 | J Zhejiang Univ Sci B | pmid:25091992 |
Basili S et al. | Aspirin reload before elective percutaneous coronary intervention: impact on serum thromboxane b2 and myocardial reperfusion indexes. | 2014 | Circ Cardiovasc Interv | pmid:25074252 |
Lattanzio S et al. | Circulating dickkopf-1 in diabetes mellitus: association with platelet activation and effects of improved metabolic control and low-dose aspirin. | 2014 | J Am Heart Assoc | pmid:25037197 |