Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Stomach Ulcer D013276 75 associated lipids
Hyperlipidemias D006949 73 associated lipids
Carcinoma, Non-Small-Cell Lung D002289 72 associated lipids
Coronary Disease D003327 70 associated lipids
Colitis D003092 69 associated lipids
Mammary Neoplasms, Experimental D008325 67 associated lipids
Liver Cirrhosis D008103 67 associated lipids
Reperfusion Injury D015427 65 associated lipids
Pain D010146 64 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Weight Loss D015431 56 associated lipids
Leukemia, Myeloid D007951 52 associated lipids
Asthma D001249 52 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Thrombosis D013927 49 associated lipids
Fatty Liver D005234 48 associated lipids
Coronary Artery Disease D003324 47 associated lipids
Metabolic Syndrome D024821 44 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Ischemic Attack, Transient D002546 42 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

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Authors Title Published Journal PubMed Link
DeFilippis AP et al. Fatty acids and TxA(2) generation, in the absence of platelet-COX-1 activity. 2014 Nutr Metab Cardiovasc Dis pmid:24370448
Wang Y et al. DanQi Pill protects against heart failure through the arachidonic acid metabolism pathway by attenuating different cyclooxygenases and leukotrienes B4. 2014 BMC Complement Altern Med pmid:24555740
van den Elsen LW et al. Dietary fish oil improves endothelial function and lowers blood pressure via suppression of sphingolipid-mediated contractions in spontaneously hypertensive rats. 2014 J. Hypertens. pmid:24569415
John F et al. Elevated levels of leukotriene B4 and thromboxane B2 distinguish chest pain of cardiac and non cardiac origin. 2013 May-Jun Indian Heart J pmid:23809385
Dudley A et al. Cyclooxygenase expression and platelet function in healthy dogs receiving low-dose aspirin. 2013 Jan-Feb J. Vet. Intern. Med. pmid:23278865
Maenthaisong R et al. Clinical pharmacology of cyclooxygenase inhibition and pharmacodynamic interaction with aspirin by floctafenine in Thai healthy subjects. 2013 Apr-Jun Int J Immunopathol Pharmacol pmid:23755755
Postula M et al. Association of plasma concentrations of salicylic acid and high on ASA platelet reactivity in type 2 diabetes patients. 2013 Cardiol J pmid:23558875
Honma S et al. Amelioration of cisplatin-induced mouse renal lesions by a cyclooxygenase (COX)-2 selective inhibitor. 2013 Eur. J. Pharmacol. pmid:23747596
Lee JJ et al. Antithrombotic and antiplatelet activities of Soshiho-tang extract. 2013 BMC Complement Altern Med pmid:23773779
Kim YJ Rhamnetin attenuates melanogenesis by suppressing oxidative stress and pro-inflammatory mediators. 2013 Biol. Pharm. Bull. pmid:23739488
Vazzana N et al. Enhanced lipid peroxidation and platelet activation as potential contributors to increased cardiovascular risk in the low-HDL phenotype. 2013 J Am Heart Assoc pmid:23557750
Dave M and Amin AR Yin-Yang regulation of prostaglandins and nitric oxide by PGD2 in human arthritis: reversal by celecoxib. 2013 Immunol. Lett. pmid:23603366
Hau CS et al. Suppressive effects of antimycotics on thymic stromal lymphopoietin production in human keratinocytes. 2013 J. Dermatol. Sci. pmid:23688403
Drew RC et al. Aspirin augments carotid-cardiac baroreflex sensitivity during muscle mechanoreflex and metaboreflex activation in humans. 2013 J. Appl. Physiol. pmid:23970529
An J et al. Blocking of thromboxane Aâ‚‚ receptor attenuates airway mucus hyperproduction induced by cigarette smoke. 2013 Eur. J. Pharmacol. pmid:23399768
Brose SA and Golovko MY Eicosanoid post-mortem induction in kidney tissue is prevented by microwave irradiation. 2013 Prostaglandins Leukot. Essent. Fatty Acids pmid:24113545
Matsunobu T et al. Thromboxane A synthase-independent production of 12-hydroxyheptadecatrienoic acid, a BLT2 ligand. 2013 J. Lipid Res. pmid:24009185
Barillà F et al. Clopidogrel plus indobufen in acute coronary syndrome patients with hypersensitivity to aspirin undergoing percutaneous coronary intervention. 2013 Platelets pmid:22646157
Lino-dos-Santos-Franco A et al. Formaldehyde inhalation reduces respiratory mechanics in a rat model with allergic lung inflammation by altering the nitric oxide/cyclooxygenase-derived products relationship. 2013 Food Chem. Toxicol. pmid:23871789
Kovarik JJ et al. Eicosanoid modulation by the short-chain fatty acid n-butyrate in human monocytes. 2013 Immunology pmid:23398566